Reactive oxygen species hydrogen peroxide mediates Kaposi's sarcoma-associated herpesvirus reactivation from latency

PLoS Pathogens

Volumn 7, Issue 5, 2011, Pages

  Ye, Fengchun ^a   Zhou, Fuchun ^a   Bedolla, Roble G ^a   Jones, Tiffany ^a   Lei, Xiufen ^a   Kang, Tao ^a   Guadalupe, Moraima ^a   Gao, Shou Jiang ^a,b  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b University of Texas Health Science Center at San Antonio   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; CATALASE; GLUTATHIONE; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; REACTIVE OXYGEN METABOLITE; SYNAPTOPHYSIN; 1,3 BUTADIENE DERIVATIVE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; IMIDAZOLE DERIVATIVE; MAPK1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRILE; PYRIDINE DERIVATIVE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL MODEL; ARTICLE; AUTOCRINE EFFECT; CONTROLLED STUDY; HUMAN HERPESVIRUS 8; HYPOXIA; LIFESPAN; LYMPHOMA; LYSIS; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PARACRINE SIGNALING; VIRUS LATENCY; VIRUS REACTIVATION; VIRUS REPLICATION; ANIMAL; CELL LINE; CELL STRAIN HEK293; DRUG ANTAGONISM; FLUORESCENT ANTIBODY TECHNIQUE; HERPES VIRUS INFECTION; HUMAN; KAPOSI SARCOMA; METABOLISM; MOUSE MUTANT; NONOBESE DIABETIC MOUSE; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; VIROLOGY; VIRUS ACTIVATION; WESTERN BLOTTING;

HUMAN HERPESVIRUS 8; MUS;

ACETYLCYSTEINE; ANIMALS; BLOTTING, WESTERN; BUTADIENES; CATALASE; CELL LINE; FLUORESCENT ANTIBODY TECHNIQUE; GLUTATHIONE; HEK293 CELLS; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 8, HUMAN; HUMANS; HYDROGEN PEROXIDE; IMIDAZOLES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MICE; MICE, INBRED NOD; MICE, SCID; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NITRILES; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIDINES; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SARCOMA, KAPOSI; SIGNAL TRANSDUCTION; VIRUS ACTIVATION; VIRUS LATENCY; VIRUS REPLICATION;

EID: 79958065575     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002054     Document Type: Article

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