메뉴 건너뛰기




Volumn 95, Issue 10, 2017, Pages 1141-1148

Role of folate in nonalcoholic fatty liver disease

Author keywords

Folate; Inflammation; Nonalcoholic fatty liver disease; Oxidative stress; Steatosis

Indexed keywords

FOLIC ACID; AUTACOID;

EID: 85030097166     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/cjpp-2016-0681     Document Type: Review
Times cited : (63)

References (115)
  • 1
    • 33644827082 scopus 로고    scopus 로고
    • Overproduction of large VLDL particles is driven by increased liver fat content in man
    • PMID:16463046
    • Adiels, M., Taskinen, M.R., Packard, C., Caslake, M.J., Soro-Paavonen, A., Westerbacka, J., et al. 2006. Overproduction of large VLDL particles is driven by increased liver fat content in man. Diabetologia, 49(4): 755-765. doi:10.1007/s00125-005-0125-z.PMID:16463046.
    • (2006) Diabetologia , vol.49 , Issue.4 , pp. 755-765
    • Adiels, M.1    Taskinen, M.R.2    Packard, C.3    Caslake, M.J.4    Soro-Paavonen, A.5    Westerbacka, J.6
  • 2
    • 84930854845 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease in 2015
    • PMID:26085906
    • Ahmed, M. 2015. Non-alcoholic fatty liver disease in 2015. World J. Hepatol. 7(11): 1450-1459. doi:10.4254/wjh.v7.i11.1450.PMID:26085906.
    • (2015) World J. Hepatol , vol.7 , Issue.11 , pp. 1450-1459
    • Ahmed, M.1
  • 3
    • 67649306197 scopus 로고    scopus 로고
    • Systematic review of risk factors for fibrosis progression in non-alcoholic steatohepatitis
    • PMID:19501928
    • Argo, C.K., Northup, P.G., Al-Osaimi, A.M., and Caldwell, S.H. 2009. Systematic review of risk factors for fibrosis progression in non-alcoholic steatohepatitis. J. Hepatol. 51(2): 371-379. doi:10.1016/j.jhep.2009.03.019.PMID:19501928.
    • (2009) J. Hepatol , vol.51 , Issue.2 , pp. 371-379
    • Argo, C.K.1    Northup, P.G.2    Al-Osaimi, A.M.3    Caldwell, S.H.4
  • 4
    • 33745790096 scopus 로고    scopus 로고
    • Folic acid inhibits homocysteine-induced superoxide anion production and nuclear factor kappa B activation in macrophages
    • PMID:16845898
    • Au-Yeung, K.K., Yip, J.C., Siow, Y.L., and O, K. 2006. Folic acid inhibits homocysteine-induced superoxide anion production and nuclear factor kappa B activation in macrophages. Can. J. Physiol. Pharmacol. 84(1): 141-147. doi:10.1139/Y05-136.PMID:16845898.
    • (2006) Can. J. Physiol. Pharmacol , vol.84 , Issue.1 , pp. 141-147
    • Au-Yeung, K.K.1    Yip, J.C.2    Siow, Y.L.3
  • 5
    • 74049120835 scopus 로고    scopus 로고
    • Total folate and folic acid intake from foods and dietary supplements in the United States: 2003-2006
    • PMID:19923379
    • Bailey, R.L., Dodd, K.W., Gahche, J.J., Dwyer, J.T., McDowell, M.A., Yetley, E.A., et al. 2010. Total folate and folic acid intake from foods and dietary supplements in the United States: 2003-2006. Am. J. Clin. Nutr. 91(1): 231-237. doi:10.3945/ajcn.2009.28427.PMID:19923379.
    • (2010) Am. J. Clin. Nutr , vol.91 , Issue.1 , pp. 231-237
    • Bailey, R.L.1    Dodd, K.W.2    Gahche, J.J.3    Dwyer, J.T.4    McDowell, M.A.5    Yetley, E.A.6
  • 6
    • 70349324816 scopus 로고    scopus 로고
    • The extremely slow and variable activity of dihydrofolate reductase in human liver and its implications for high folic acid intake
    • PMID:19706381
    • Bailey, S.W., and Ayling, J.E. 2009. The extremely slow and variable activity of dihydrofolate reductase in human liver and its implications for high folic acid intake. Proc. Natl. Acad. Sci. U.S.A. 106(36): 15424-15429. doi:10.1073/pnas.0902072106.PMID:19706381.
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , Issue.36 , pp. 15424-15429
    • Bailey, S.W.1    Ayling, J.E.2
  • 7
    • 0023789244 scopus 로고
    • In vitro evidence for the involvement of mitochondrial folate metabolism in the supply of cytoplasmic one-carbon units
    • PMID:2475123
    • Barlowe, C.K., and Appling, D.R. 1988. In vitro evidence for the involvement of mitochondrial folate metabolism in the supply of cytoplasmic one-carbon units. Biofactors, 1(2): 171-176. PMID:2475123.
    • (1988) Biofactors , vol.1 , Issue.2 , pp. 171-176
    • Barlowe, C.K.1    Appling, D.R.2
  • 8
    • 84919754666 scopus 로고    scopus 로고
    • Obesity is associated with increased red blood cell folate despite lower dietary intakes and serum concentrations
    • PMID:25527662
    • Bird, J.K., Ronnenberg, A.G., Choi, S.W., Du, F., Mason, J.B., and Liu, Z. 2015. Obesity is associated with increased red blood cell folate despite lower dietary intakes and serum concentrations. J. Nutr. 145(1): 79-86. doi:10.3945/jn.114.199117.PMID:25527662.
    • (2015) J. Nutr , vol.145 , Issue.1 , pp. 79-86
    • Bird, J.K.1    Ronnenberg, A.G.2    Choi, S.W.3    Du, F.4    Mason, J.B.5    Liu, Z.6
  • 9
    • 84884860377 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease, hepatic insulin resistance, and type 2 diabetes
    • PMID:23929732
    • Birkenfeld, A.L., and Shulman, G.I. 2014. Nonalcoholic fatty liver disease, hepatic insulin resistance, and type 2 diabetes. Hepatology, 59(2): 713-723. doi:10.1002/hep.26672.PMID:23929732.
    • (2014) Hepatology , vol.59 , Issue.2 , pp. 713-723
    • Birkenfeld, A.L.1    Shulman, G.I.2
  • 10
    • 33747588534 scopus 로고    scopus 로고
    • Neural tube defects and folate: Case far from closed
    • PMID:16924261
    • Blom, H.J., Shaw, G.M., den Heijer, M., and Finnell, R.H. 2006. Neural tube defects and folate: case far from closed. Nat. Rev. Neurosci. 7(9): 724-731. doi:10.1038/nrn1986.PMID:16924261.
    • (2006) Nat. Rev. Neurosci , vol.7 , Issue.9 , pp. 724-731
    • Blom, H.J.1    Shaw, G.M.2    Den Heijer, M.3    Finnell, R.H.4
  • 11
    • 0029066299 scopus 로고
    • A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes
    • PMID:7563456
    • Boushey, C.J., Beresford, S.A., Omenn, G.S., and Motulsky, A.G. 1995. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. JAMA, 274(13): 1049-1057. PMID:7563456.
    • (1995) JAMA , vol.274 , Issue.13 , pp. 1049-1057
    • Boushey, C.J.1    Beresford, S.A.2    Omenn, G.S.3    Motulsky, A.G.4
  • 12
    • 0032497941 scopus 로고    scopus 로고
    • Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease: The result of a meta-analysis
    • PMID:9843457
    • Brattström, L., Wilcken, D.E., Ohrvik, J., and Brudin, L. 1998. Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease: the result of a meta-analysis. Circulation, 98(23): 2520-2526. doi:10.1161/01.CIR.98.23.2520.PMID:9843457.
    • (1998) Circulation , vol.98 , Issue.23 , pp. 2520-2526
    • Brattström, L.1    Wilcken, D.E.2    Ohrvik, J.3    Brudin, L.4
  • 13
    • 78649433367 scopus 로고    scopus 로고
    • Histopathology of nonalcoholic fatty liver disease
    • PMID:21072891
    • Brunt, E.M., and Tiniakos, D.G. 2010. Histopathology of nonalcoholic fatty liver disease. World J. Gastroenterol. 16(42): 5286-5296. doi:10.3748/wjg.v16.i42.5286.PMID:21072891.
    • (2010) World J. Gastroenterol , vol.16 , Issue.42 , pp. 5286-5296
    • Brunt, E.M.1    Tiniakos, D.G.2
  • 14
    • 84929515859 scopus 로고    scopus 로고
    • Insights into severe 5,10-methylenetetrahydrofolate reductase deficiency: Molecular genetic and enzymatic characterization of 76 patients
    • PMID:25736335
    • Burda, P., Schäfer, A., Suormala, T., Rummel, T., Bürer, C., Heuberger, D., et al. 2015. Insights into severe 5,10-methylenetetrahydrofolate reductase deficiency: molecular genetic and enzymatic characterization of 76 patients. Hum. Mutat. 36(6): 611-621. doi:10.1002/humu.22779.PMID:25736335.
    • (2015) Hum. Mutat , vol.36 , Issue.6 , pp. 611-621
    • Burda, P.1    Schäfer, A.2    Suormala, T.3    Rummel, T.4    Bürer, C.5    Heuberger, D.6
  • 15
    • 84957812743 scopus 로고    scopus 로고
    • The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)
    • PMID:26823198
    • Buzzetti, E., Pinzani, M., and Tsochatzis, E.A. 2016. The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD). Metabolism, 65(8): 1038-1048. doi:10.1016/j.metabol.2015.12.012.PMID:26823198.
    • (2016) Metabolism , vol.65 , Issue.8 , pp. 1038-1048
    • Buzzetti, E.1    Pinzani, M.2    Tsochatzis, E.A.3
  • 16
    • 0029989191 scopus 로고    scopus 로고
    • Folate synthesized by bacteria in the human upper small intestine is assimilated by the host
    • PMID:8613033
    • Camilo, E., Zimmerman, J., Mason, J.B., Golner, B., Russell, R., Selhub, J., and Rosenberg, I.H. 1996. Folate synthesized by bacteria in the human upper small intestine is assimilated by the host. Gastroenterology, 110(4): 991-998. doi:10.1053/gast.1996.v110.pm8613033.PMID:8613033.
    • (1996) Gastroenterology , vol.110 , Issue.4 , pp. 991-998
    • Camilo, E.1    Zimmerman, J.2    Mason, J.B.3    Golner, B.4    Russell, R.5    Selhub, J.6    Rosenberg, I.H.7
  • 17
    • 79851500161 scopus 로고    scopus 로고
    • Dihydrofolate reductase deficiency due to a homozygous DHFR mutation causes megaloblastic anemia and cerebral folate deficiency leading to severe neurologic disease
    • PMID:21310277
    • Cario, H., Smith, D.E., Blom, H., Blau, N., Bode, H., Holzmann, K., et al. 2011. Dihydrofolate reductase deficiency due to a homozygous DHFR mutation causes megaloblastic anemia and cerebral folate deficiency leading to severe neurologic disease. Am. J. Hum. Genet. 88(2): 226-231. doi:10.1016/j.ajhg.2011.01.007.PMID:21310277.
    • (2011) Am. J. Hum. Genet , vol.88 , Issue.2 , pp. 226-231
    • Cario, H.1    Smith, D.E.2    Blom, H.3    Blau, N.4    Bode, H.5    Holzmann, K.6
  • 18
    • 77955692711 scopus 로고    scopus 로고
    • CDC Grand Rounds: Additional opportunities to prevent neural tube defects with folic acid fortification
    • PMID:20703205
    • CDC. 2010. CDC Grand Rounds: additional opportunities to prevent neural tube defects with folic acid fortification. MMWR Morb. Mortal. Wkly. Rep. 59(31): 980-984. PMID:20703205.
    • (2010) MMWR Morb. Mortal. Wkly. Rep , vol.59 , Issue.31 , pp. 980-984
  • 19
    • 84861543083 scopus 로고    scopus 로고
    • The diagnosis and management of non-alcoholic fatty liver disease: Practice guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association
    • PMID:22488764
    • Chalasani, N., Younossi, Z., Lavine, J.E., Diehl, A.M., Brunt, E.M., Cusi, K., et al. 2012. The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association. Hepatology, 55(6): 2005-2023. doi:10.1002/hep.25762.PMID:22488764.
    • (2012) Hepatology , vol.55 , Issue.6 , pp. 2005-2023
    • Chalasani, N.1    Younossi, Z.2    Lavine, J.E.3    Diehl, A.M.4    Brunt, E.M.5    Cusi, K.6
  • 20
    • 84857124389 scopus 로고    scopus 로고
    • Folate depletion changes gene expression of fatty acid metabolism, DNA synthesis, and circadian cycle in male mice
    • PMID:22348461
    • Champier, J., Claustrat, F., Nazaret, N., Fèvre Montange, M., and Claustrat, B. 2012. Folate depletion changes gene expression of fatty acid metabolism, DNA synthesis, and circadian cycle in male mice. Nutr. Res. 32(2): 124-132. doi:10.1016/j.nutres.2011.12.012.PMID:22348461.
    • (2012) Nutr. Res , vol.32 , Issue.2 , pp. 124-132
    • Champier, J.1    Claustrat, F.2    Nazaret, N.3    Fèvre Montange, M.4    Claustrat, B.5
  • 21
    • 34548463106 scopus 로고    scopus 로고
    • Changes in mitochondrial DNA deletion, content, and biogenesis in folate-deficient tissues of young rats depend on mitochondrial folate and oxidative DNA injuries
    • PMID:17709439
    • Chou, Y.F., Yu, C.C., and Huang, R.F. 2007. Changes in mitochondrial DNA deletion, content, and biogenesis in folate-deficient tissues of young rats depend on mitochondrial folate and oxidative DNA injuries. J. Nutr. 137(9): 2036-2042. PMID:17709439.
    • (2007) J. Nutr , vol.137 , Issue.9 , pp. 2036-2042
    • Chou, Y.F.1    Yu, C.C.2    Huang, R.F.3
  • 22
    • 77958130827 scopus 로고    scopus 로고
    • Steatosis in mice is associated with gender, folate intake, and expression of genes of one-carbon metabolism
    • PMID:20724492
    • Christensen, K.E., Wu, Q., Wang, X., Deng, L., Caudill, M.A., and Rozen, R. 2010. Steatosis in mice is associated with gender, folate intake, and expression of genes of one-carbon metabolism. J. Nutr. 140(10): 1736-1741. doi:10.3945/jn.110.124917.PMID:20724492.
    • (2010) J. Nutr , vol.140 , Issue.10 , pp. 1736-1741
    • Christensen, K.E.1    Wu, Q.2    Wang, X.3    Deng, L.4    Caudill, M.A.5    Rozen, R.6
  • 23
    • 0034329105 scopus 로고    scopus 로고
    • Lowering blood homocysteine with folic acid-based supplements: Meta-analysis of randomised trials
    • PMID: 11339443
    • Clarke, R. 2000. Lowering blood homocysteine with folic acid-based supplements: meta-analysis of randomised trials. Indian Heart J. 52: S59-S64. PMID: 11339443.
    • (2000) Indian Heart J , vol.52 , pp. S59-S64
    • Clarke, R.1
  • 24
    • 79959517565 scopus 로고    scopus 로고
    • Human fatty liver disease: Old questions and new insights
    • PMID:21700865
    • Cohen, J.C., Horton, J.D., and Hobbs, H.H. 2011. Human fatty liver disease: old questions and new insights. Science, 332(6037): 1519-1523. doi:10.1126/science.1204265.PMID:21700865.
    • (2011) Science , vol.332 , Issue.6037 , pp. 1519-1523
    • Cohen, J.C.1    Horton, J.D.2    Hobbs, H.H.3
  • 25
    • 84902544544 scopus 로고    scopus 로고
    • Novel insights on interactions between folate and lipid metabolism
    • PMID:24353111
    • da Silva, R.P., Kelly, K.B., Al Rajabi, A., and Jacobs, R.L. 2014. Novel insights on interactions between folate and lipid metabolism. Biofactors, 40(3): 277-283. doi:10.1002/biof.1154.PMID:24353111.
    • (2014) Biofactors , vol.40 , Issue.3 , pp. 277-283
    • Da Silva, R.P.1    Kelly, K.B.2    Al Rajabi, A.3    Jacobs, R.L.4
  • 26
    • 30044431801 scopus 로고    scopus 로고
    • From fat to inflammation
    • PMID:16401483
    • Day, C.P. 2006. From fat to inflammation. Gastroenterology, 130(1): 207-210. doi:10.1053/j.gastro.2005.11.017.PMID:16401483.
    • (2006) Gastroenterology , vol.130 , Issue.1 , pp. 207-210
    • Day, C.P.1
  • 27
    • 0031947715 scopus 로고    scopus 로고
    • Steatohepatitis: A tale of two “hits”?
    • PMID:9547102
    • Day, C.P., and James, O.F. 1998. Steatohepatitis: a tale of two “hits”? Gastroenterology, 114(4): 842-845. doi:10.1016/S0016-5085(98)70599-2.PMID:9547102.
    • (1998) Gastroenterology , vol.114 , Issue.4 , pp. 842-845
    • Day, C.P.1    James, O.F.2
  • 28
    • 34447342598 scopus 로고    scopus 로고
    • Reduction in neural-tube defects after folic acid fortification in Canada
    • PMID:17625125
    • De Wals, P., Tairou, F., Van Allen, M.I., Uh, S.H., Lowry, R.B., Sibbald, B., et al. 2007. Reduction in neural-tube defects after folic acid fortification in Canada. N. Engl. J. Med. 357(2): 135-142. doi:10.1056/NEJMoa067103.PMID:17625125.
    • (2007) N. Engl. J. Med , vol.357 , Issue.2 , pp. 135-142
    • De Wals, P.1    Tairou, F.2    Van Allen, M.I.3    Uh, S.H.4    Lowry, R.B.5    Sibbald, B.6
  • 29
    • 58149489228 scopus 로고    scopus 로고
    • Dietary intake and status of folate and vitamin B12 and their association with homocysteine and cardiovascular disease in European populations
    • PMID:17851461
    • Dhonukshe-Rutten, R.A., de Vries, J.H., de Bree, A., van der Put, N., van Staveren, W.A., and de Groot, L.C. 2009. Dietary intake and status of folate and vitamin B12 and their association with homocysteine and cardiovascular disease in European populations. Eur. J. Clin. Nutr. 63(1): 18-30. doi:10.1038/sj.ejcn.1602897.PMID:17851461.
    • (2009) Eur. J. Clin. Nutr , vol.63 , Issue.1 , pp. 18-30
    • Dhonukshe-Rutten, R.A.1    De Vries, J.H.2    De Bree, A.3    Van Der Put, N.4    Van Staveren, W.A.5    De Groot, L.C.6
  • 30
    • 18244382304 scopus 로고    scopus 로고
    • Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
    • PMID:15864352
    • Donnelly, K.L., Smith, C.I., Schwarzenberg, S.J., Jessurun, J., Boldt, M.D., and Parks, E.J. 2005. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J. Clin. Invest. 115(5): 1343-1351. doi:10.1172/JCI23621.PMID:15864352.
    • (2005) J. Clin. Invest , vol.115 , Issue.5 , pp. 1343-1351
    • Donnelly, K.L.1    Smith, C.I.2    Schwarzenberg, S.J.3    Jessurun, J.4    Boldt, M.D.5    Parks, E.J.6
  • 31
    • 34548321204 scopus 로고    scopus 로고
    • Nuclear factor-kappaB and the hepatic inflammation-fibrosis-cancer axis
    • PMID:17661407
    • Elsharkawy, A.M., and Mann, D.A. 2007. Nuclear factor-kappaB and the hepatic inflammation-fibrosis-cancer axis. Hepatology, 46(2): 590-597. doi:10.1002/hep.21802.PMID:17661407.
    • (2007) Hepatology , vol.46 , Issue.2 , pp. 590-597
    • Elsharkawy, A.M.1    Mann, D.A.2
  • 32
    • 38649111018 scopus 로고    scopus 로고
    • Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease
    • PMID:18242210
    • Fabbrini, E., Mohammed, B.S., Magkos, F., Korenblat, K.M., Patterson, B.W., and Klein, S. 2008. Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease. Gastroenterology, 134(2): 424-431. doi:10.1053/j.gastro.2007.11.038.PMID:18242210.
    • (2008) Gastroenterology , vol.134 , Issue.2 , pp. 424-431
    • Fabbrini, E.1    Mohammed, B.S.2    Magkos, F.3    Korenblat, K.M.4    Patterson, B.W.5    Klein, S.6
  • 33
    • 75449094816 scopus 로고    scopus 로고
    • Obesity and nonalcoholic fatty liver disease: Biochemical, metabolic, and clinical implications
    • PMID:20041406
    • Fabbrini, E., Sullivan, S., and Klein, S. 2010. Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications. Hepatology, 51(2): 679-689. doi:10.1002/hep.23280.PMID:20041406.
    • (2010) Hepatology , vol.51 , Issue.2 , pp. 679-689
    • Fabbrini, E.1    Sullivan, S.2    Klein, S.3
  • 34
    • 84902332213 scopus 로고    scopus 로고
    • Quantitative flux analysis reveals folate-dependent NADPH production
    • PMID:24805240
    • Fan, J., Ye, J., Kamphorst, J.J., Shlomi, T., Thompson, C.B., and Rabinowitz, J.D. 2014. Quantitative flux analysis reveals folate-dependent NADPH production. Nature, 510(7504): 298-302. doi:10.1038/nature13236.PMID:24805240.
    • (2014) Nature , vol.510 , Issue.7504 , pp. 298-302
    • Fan, J.1    Ye, J.2    Kamphorst, J.J.3    Shlomi, T.4    Thompson, C.B.5    Rabinowitz, J.D.6
  • 35
    • 33644547706 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: From steatosis to cirrhosis
    • PMID:16447287
    • Farrell, G.C., and Larter, C.Z. 2006. Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology, 43: S99-S112. doi:10.1002/hep.20973.PMID:16447287.
    • (2006) Hepatology , vol.43 , pp. SS99-S112
    • Farrell, G.C.1    Larter, C.Z.2
  • 36
    • 0029114541 scopus 로고
    • Nascent VLDL phospholipid composition is altered when phosphatidylcholine biosynthesis is inhibited: Evidence for a novel mechanism that regulates VLDL secretion
    • PMID: 7548179
    • Fast, D.G., and Vance, D.E. 1995. Nascent VLDL phospholipid composition is altered when phosphatidylcholine biosynthesis is inhibited: evidence for a novel mechanism that regulates VLDL secretion. Biochim. Biophys. Acta, Lipids Lipid Metab. 1258(2): 159-168. doi:10.1016/0005-2760(95)00116-T.PMID:7548179.
    • (1995) Biochim. Biophys. Acta, Lipids Lipid Metab , vol.1258 , Issue.2 , pp. 159-168
    • Fast, D.G.1    Vance, D.E.2
  • 37
    • 31044452644 scopus 로고    scopus 로고
    • High prevalence of folic acid and vitamin B12 deficiencies in infants, children, adolescents and pregnant women in Venezuela
    • PMID:16015269
    • García-Casal, M.N., Osorio, C., Landaeta, M., Leets, I., Matus, P., Fazzino, F., and Marcos, E. 2005. High prevalence of folic acid and vitamin B12 deficiencies in infants, children, adolescents and pregnant women in Venezuela. Eur. J. Clin. Nutr. 59(9): 1064-1070. doi:10.1038/sj.ejcn.1602212.PMID:16015269.
    • (2005) Eur. J. Clin. Nutr , vol.59 , Issue.9 , pp. 1064-1070
    • García-Casal, M.N.1    Osorio, C.2    Landaeta, M.3    Leets, I.4    Matus, P.5    Fazzino, F.6    Marcos, E.7
  • 38
    • 38349042194 scopus 로고    scopus 로고
    • PH-Dependent radical scavenging activity of folates
    • PMID:17848080
    • Gliszczyńska-Świgło, A., and Muzolf, M. 2007. pH-Dependent radical scavenging activity of folates. J. Agric. Food Chem. 55(20): 8237-8242. doi:10.1021/jf070986x.PMID:17848080.
    • (2007) J. Agric. Food Chem , vol.55 , Issue.20 , pp. 8237-8242
    • Gliszczyńska-Świgło, A.1    Muzolf, M.2
  • 39
    • 2942572700 scopus 로고    scopus 로고
    • Measuring reactive species and oxidative damage in vivo and in cell culture: How should you do it and what do the results mean
    • PMID:15155533
    • Halliwell, B., and Whiteman, M. 2004. Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean? Br. J. Pharmacol. 142(2): 231-255. doi:10.1038/sj.bjp.0705776.PMID:15155533.
    • (2004) Br. J. Pharmacol , vol.142 , Issue.2 , pp. 231-255
    • Halliwell, B.1    Whiteman, M.2
  • 40
    • 84858782079 scopus 로고    scopus 로고
    • AMPK: A nutrient and energy sensor that maintains energy homeostasis
    • PMID:22436748
    • Hardie, D.G., Ross, F.A., and Hawley, S.A. 2012. AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat. Rev. Mol. Cell Biol. 13(4): 251-262. doi:10.1038/nrm3311.PMID:22436748.
    • (2012) Nat. Rev. Mol. Cell Biol , vol.13 , Issue.4 , pp. 251-262
    • Hardie, D.G.1    Ross, F.A.2    Hawley, S.A.3
  • 41
    • 78649549021 scopus 로고    scopus 로고
    • Diversity in antioxidant response enzymes in progressive stages of human nonalcoholic fatty liver disease
    • PMID:20805291
    • Hardwick, R.N., Fisher, C.D., Canet, M.J., Lake, A.D., and Cherrington, N.J. 2010. Diversity in antioxidant response enzymes in progressive stages of human nonalcoholic fatty liver disease. Drug Metab. Dispos. 38(12): 2293-2301. doi:10.1124/dmd.110.035006.PMID:20805291.
    • (2010) Drug Metab. Dispos , vol.38 , Issue.12 , pp. 2293-2301
    • Hardwick, R.N.1    Fisher, C.D.2    Canet, M.J.3    Lake, A.D.4    Cherrington, N.J.5
  • 42
    • 0030856008 scopus 로고    scopus 로고
    • Vitamins C, E and A and heme oxygenase in rats fed methyl/folate-deficient diets
    • Henning, S.M., Swendseid, M.E., Ivandic, B.T., and Liao, F. 1997. Vitamins C, E and A and heme oxygenase in rats fed methyl/folate-deficient diets. Free Radical Biol. Med. 23(6): 936-942. doi:10.1016/S0891-5849(97)00097-X.
    • (1997) Free Radical Biol. Med. , vol.23 , Issue.6 , pp. 936-942
    • Henning, S.M.1    Swendseid, M.E.2    Ivandic, B.T.3    Liao, F.4
  • 43
    • 0037064008 scopus 로고    scopus 로고
    • Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses
    • PMID:12161434
    • Herbig, K., Chiang, E.P., Lee, L.R., Hills, J., Shane, B., and Stover, P.J. 2002. Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses. J. Biol. Chem. 277(41): 38381-38389. doi:10.1074/jbc.M205000200.PMID:12161434.
    • (2002) J. Biol. Chem , vol.277 , Issue.41 , pp. 38381-38389
    • Herbig, K.1    Chiang, E.P.2    Lee, L.R.3    Hills, J.4    Shane, B.5    Stover, P.J.6
  • 44
    • 13844267785 scopus 로고    scopus 로고
    • Serum folate and homocysteine levels in obese females with nonalcoholic fatty liver
    • PMID:15723740
    • Hirsch, S., Poniachick, J., Avendaño, M., Csendes, A., Burdiles, P., Smok, G., et al. 2005. Serum folate and homocysteine levels in obese females with nonalcoholic fatty liver. Nutrition, 21(2): 137-141. doi:10.1016/j.nut.2004.03.022.PMID:15723740.
    • (2005) Nutrition , vol.21 , Issue.2 , pp. 137-141
    • Hirsch, S.1    Poniachick, J.2    Avendaño, M.3    Csendes, A.4    Burdiles, P.5    Smok, G.6
  • 45
    • 0037164104 scopus 로고    scopus 로고
    • Homocysteine and risk of ischemic heart disease and stroke: A meta-analysis
    • PMID:12387654
    • Homocysteine Studies Collaboration. 2002. Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis. JAMA, 288(16): 2015-2022. doi:10.1001/jama.288.16.2015.PMID:12387654.
    • (2002) JAMA , vol.288 , Issue.16 , pp. 2015-2022
  • 46
    • 0027177342 scopus 로고
    • 5-Methyltetrahydrofolate transport in basolateral membrane vesicles from human liver
    • PMID:8317394
    • Horne, D.W., Reed, K.A., Hoefs, J., and Said, H.M. 1993. 5-Methyltetrahydrofolate transport in basolateral membrane vesicles from human liver. Am. J. Clin. Nutr. 58(1): 80-84. PMID:8317394.
    • (1993) Am. J. Clin. Nutr , vol.58 , Issue.1 , pp. 80-84
    • Horne, D.W.1    Reed, K.A.2    Hoefs, J.3    Said, H.M.4
  • 47
    • 84975126975 scopus 로고    scopus 로고
    • Application of the key events doseresponse framework to folate metabolism
    • PMID:25674817
    • Hu, J., Wang, B., and Sahyoun, N.R. 2016. Application of the key events doseresponse framework to folate metabolism. Crit. Rev. Food Sci. Nutr. 56(8): 1325-1333. doi:10.1080/10408398.2013.807221.PMID:25674817.
    • (2016) Crit. Rev. Food Sci. Nutr , vol.56 , Issue.8 , pp. 1325-1333
    • Hu, J.1    Wang, B.2    Sahyoun, N.R.3
  • 48
    • 0035182406 scopus 로고    scopus 로고
    • Folate depletion and elevated plasma homocysteine promote oxidative stress in rat livers
    • PMID:11208935
    • Huang, R.F., Hsu, Y.C., Lin, H.L., and Yang, F.L. 2001. Folate depletion and elevated plasma homocysteine promote oxidative stress in rat livers. J. Nutr. 131(1): 33-38. PMID:11208935.
    • (2001) J. Nutr , vol.131 , Issue.1 , pp. 33-38
    • Huang, R.F.1    Hsu, Y.C.2    Lin, H.L.3    Yang, F.L.4
  • 49
    • 78651345743 scopus 로고    scopus 로고
    • Folic acid supplementation inhibits NADPH oxidase-mediated superoxide anion production in the kidney
    • O, K, PMID:20980407
    • Hwang, S.Y., Siow, Y.L., Au-Yeung, K.K., House, J., and O, K. 2011. Folic acid supplementation inhibits NADPH oxidase-mediated superoxide anion production in the kidney. Am. J. Physiol. Renal Physiol. 300(1): F189-F198. doi:10.1152/ajprenal.00272.2010.PMID:20980407.
    • (2011) Am. J. Physiol. Renal Physiol , vol.300 , Issue.1 , pp. F189-F198
    • Hwang, S.Y.1    Siow, Y.L.2    Au-Yeung, K.K.3    House, J.4
  • 50
    • 21644456797 scopus 로고    scopus 로고
    • Institute of Medicine (US) Standing Committee on the Scientific Evaluation of Dietary Reference Intakes and its Panel on Folate, Other B Vitamins, and Choline. 1998. Dietary reference intakes for thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin, and choline. The National Academies Press, Washington, D.C
    • IDF. 2005. The IDF consensus worldwide definition of the metabolic syndrome. Institute of Medicine (US) Standing Committee on the Scientific Evaluation of Dietary Reference Intakes and its Panel on Folate, Other B Vitamins, and Choline. 1998. Dietary reference intakes for thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin, and choline. The National Academies Press, Washington, D.C.
    • (2005) The IDF Consensus Worldwide Definition of the Metabolic Syndrome
  • 51
    • 0142169939 scopus 로고    scopus 로고
    • Inflammatory cytokines and cardiovascular disease
    • PMID:14561160
    • Ito, T., and Ikeda, U. 2003. Inflammatory cytokines and cardiovascular disease. Curr. Drug Targets: Inflammation Allergy, 2(3): 257-265. doi:10.2174/1568010033484106.PMID:14561160.
    • (2003) Curr. Drug Targets: Inflammation Allergy , vol.2 , Issue.3 , pp. 257-265
    • Ito, T.1    Ikeda, U.2
  • 52
    • 70449463427 scopus 로고    scopus 로고
    • Folate: A functional food constituent
    • PMID:20492126
    • Iyer, R., and Tomar, S.K. 2009. Folate: a functional food constituent. J. Food Sci. 74(9): R114-R122. doi:10.1111/j.1750-3841.2009.01359.x.PMID:20492126.
    • (2009) J. Food Sci , vol.74 , Issue.9 , pp. R114-R122
    • Iyer, R.1    Tomar, S.K.2
  • 53
    • 0035876883 scopus 로고    scopus 로고
    • Free radical scavenging behavior of folic acid: Evidence for possible antioxidant activity
    • Joshi, R., Adhikari, S., Patro, B.S., Chattopadhyay, S., and Mukherjee, T. 2001. Free radical scavenging behavior of folic acid: evidence for possible antioxidant activity. Free Radical Biol. Med. 30(12): 1390-1399. doi:10.1016/S0891-5849(01)00543-3.
    • (2001) Free Radical Biol. Med , vol.30 , Issue.12 , pp. 1390-1399
    • Joshi, R.1    Adhikari, S.2    Patro, B.S.3    Chattopadhyay, S.4    Mukherjee, T.5
  • 54
    • 84904307366 scopus 로고    scopus 로고
    • Reactive oxygen species and redox compartmentalization
    • PMID:25161621
    • Kaludercic, N., Deshwal, S., and Di Lisa, F. 2014. Reactive oxygen species and redox compartmentalization. Front. Physiol. 5: 285. doi:10.3389/fphys.2014.00285.PMID:25161621.
    • (2014) Front. Physiol. , vol.5 , pp. 285
    • Kaludercic, N.1    Deshwal, S.2    Di Lisa, F.3
  • 55
    • 0028073690 scopus 로고
    • Severe folate deficiency causes secondary depletion of choline and phosphocholine in rat liver
    • PMID:7965204
    • Kim, Y.I., Miller, J.W., da Costa, K.A., Nadeau, M., Smith, D., Selhub, J., et al. 1994. Severe folate deficiency causes secondary depletion of choline and phosphocholine in rat liver. J. Nutr. 124(11): 2197-2203. PMID:7965204.
    • (1994) J. Nutr , vol.124 , Issue.11 , pp. 2197-2203
    • Kim, Y.I.1    Miller, J.W.2    Da Costa, K.A.3    Nadeau, M.4    Smith, D.5    Selhub, J.6
  • 56
    • 20044374023 scopus 로고    scopus 로고
    • Design and validation of a histological scoring system for nonalcoholic fatty liver disease
    • PMID:15915461
    • Kleiner, D.E., Brunt, E.M., Van Natta, M., Behling, C., Contos, M.J., Cummings, O.W., et al. 2005. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology, 41(6): 1313-1321. doi:10.1002/hep.20701.PMID:15915461.
    • (2005) Hepatology , vol.41 , Issue.6 , pp. 1313-1321
    • Kleiner, D.E.1    Brunt, E.M.2    Van Natta, M.3    Behling, C.4    Contos, M.J.5    Cummings, O.W.6
  • 57
    • 35148881190 scopus 로고    scopus 로고
    • Re-evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease
    • PMID:17671740
    • Kohjima, M., Enjoji, M., Higuchi, N., Kato, M., Kotoh, K., Yoshimoto, T., et al. 2007. Re-evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease. Int. J. Mol. Med. 20(3): 351-358. PMID:17671740.
    • (2007) Int. J. Mol. Med , vol.20 , Issue.3 , pp. 351-358
    • Kohjima, M.1    Enjoji, M.2    Higuchi, N.3    Kato, M.4    Kotoh, K.5    Yoshimoto, T.6
  • 58
    • 84871829504 scopus 로고    scopus 로고
    • Folate deficiency enhances the inflammatory response of macrophages
    • PMID:23280395
    • Kolb, A.F., and Petrie, L. 2013. Folate deficiency enhances the inflammatory response of macrophages. Mol. Immunol. 54(2): 164-172. doi:10.1016/j.molimm.2012.11.012.PMID:23280395.
    • (2013) Mol. Immunol , vol.54 , Issue.2 , pp. 164-172
    • Kolb, A.F.1    Petrie, L.2
  • 59
    • 70349094101 scopus 로고    scopus 로고
    • Folic acid supplementation modifies beta-adrenoceptor-mediated in vitro lipolysis of obese/diabetic (+db/+db) mice
    • Lam, T.Y., Seto, S.W., Au, A.L., Poon, C.C., Li, R.W., Lam, H.Y., et al. 2009. Folic acid supplementation modifies beta-adrenoceptor-mediated in vitro lipolysis of obese/diabetic (+db/+db) mice. Exp. Biol. Med. 234(9): 1047-1055. doi:10.3181/0902-RM-44.
    • (2009) Exp. Biol. Med , vol.234 , Issue.9 , pp. 1047-1055
    • Lam, T.Y.1    Seto, S.W.2    Au, A.L.3    Poon, C.C.4    Li, R.W.5    Lam, H.Y.6
  • 60
    • 56549117448 scopus 로고    scopus 로고
    • Animal models of NASH: Getting both pathology and metabolic context right
    • PMID:18752564
    • Larter, C.Z., and Yeh, M.M. 2008. Animal models of NASH: getting both pathology and metabolic context right. J. Gastroenterol. Hepatol. 23(11): 1635-1648. doi:10.1111/j.1440-1746.2008.05543.x.PMID:18752564.
    • (2008) J. Gastroenterol. Hepatol , vol.23 , Issue.11 , pp. 1635-1648
    • Larter, C.Z.1    Yeh, M.M.2
  • 61
    • 43249110882 scopus 로고    scopus 로고
    • Phosphatidylcholine and choline homeostasis
    • PMID:18204095
    • Li, Z., and Vance, D.E. 2008. Phosphatidylcholine and choline homeostasis. J. Lipid Res. 49(6): 1187-1194. doi:10.1194/jlr.R700019-JLR200.PMID:18204095.
    • (2008) J. Lipid Res , vol.49 , Issue.6 , pp. 1187-1194
    • Li, Z.1    Vance, D.E.2
  • 62
    • 85047691331 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease: A multicentre clinical study by the Italian Association for the Study of the Liver
    • PMID:15248380
    • Loguercio, C., De Simone, T., D’Auria, M.V., de Sio, I., Federico, A., Tuccillo, C., et al. 2004. Non-alcoholic fatty liver disease: a multicentre clinical study by the Italian Association for the Study of the Liver. Dig. Liver Dis. 36(6): 398-405. doi:10.1016/S1590-8658(04)00094-5.PMID:15248380.
    • (2004) Dig. Liver Dis , vol.36 , Issue.6 , pp. 398-405
    • Loguercio, C.1    De Simone, T.2    D’Auria, M.V.3    De Sio, I.4    Federico, A.5    Tuccillo, C.6
  • 63
    • 33645753544 scopus 로고    scopus 로고
    • Homocysteine lowering with folic acid and B vitamins in vascular disease
    • PMID:16531613
    • Lonn, E., Yusuf, S., Arnold, M.J., Sheridan, P., Pogue, J., Micks, M., et al. 2006. Homocysteine lowering with folic acid and B vitamins in vascular disease. N. Engl. J. Med. 354(15): 1567-1577. doi:10.1056/NEJMoa060900.PMID:16531613.
    • (2006) N. Engl. J. Med , vol.354 , Issue.15 , pp. 1567-1577
    • Lonn, E.1    Yusuf, S.2    Arnold, M.J.3    Sheridan, P.4    Pogue, J.5    Micks, M.6
  • 64
    • 0033808685 scopus 로고    scopus 로고
    • Folic acid: Nutritional biochemistry, molecular biology, and role in disease processes
    • PMID:11001804
    • Lucock, M. 2000. Folic acid: nutritional biochemistry, molecular biology, and role in disease processes. Mol. Genet. Metab. 71(1-2): 121-138. doi:10.1006/mgme.2000.3027.PMID:11001804.
    • (2000) Mol. Genet. Metab , vol.71 , Issue.1-2 , pp. 121-138
    • Lucock, M.1
  • 65
    • 43449106509 scopus 로고    scopus 로고
    • Measures of adiposity and body fat distribution in relation to serum folate levels in postmenopausal women in a feeding study
    • PMID:17457338
    • Mahabir, S., Ettinger, S., Johnson, L., Baer, D.J., Clevidence, B.A., Hartman, T.J., and Taylor, P.R. 2008. Measures of adiposity and body fat distribution in relation to serum folate levels in postmenopausal women in a feeding study. Eur. J. Clin. Nutr. 62(5): 644-650. doi:10.1038/sj.ejcn.1602771.PMID:17457338.
    • (2008) Eur. J. Clin. Nutr , vol.62 , Issue.5 , pp. 644-650
    • Mahabir, S.1    Ettinger, S.2    Johnson, L.3    Baer, D.J.4    Clevidence, B.A.5    Hartman, T.J.6    Taylor, P.R.7
  • 66
    • 0035431018 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: A feature of the metabolic syndrome
    • PMID:11473047
    • Marchesini, G., Brizi, M., Bianchi, G., Tomassetti, S., Bugianesi, E., Lenzi, M., et al. 2001. Nonalcoholic fatty liver disease: a feature of the metabolic syndrome. Diabetes, 50(8): 1844-1850. doi:10.2337/diabetes.50.8.1844.PMID:11473047.
    • (2001) Diabetes , vol.50 , Issue.8 , pp. 1844-1850
    • Marchesini, G.1    Brizi, M.2    Bianchi, G.3    Tomassetti, S.4    Bugianesi, E.5    Lenzi, M.6
  • 67
    • 79959813724 scopus 로고    scopus 로고
    • Cytokines, macrophage lipid metabolism and foam cells: Implications for cardiovascular disease therapy
    • PMID:21601592
    • McLaren, J.E., Michael, D.R., Ashlin, T.G., and Ramji, D.P. 2011. Cytokines, macrophage lipid metabolism and foam cells: implications for cardiovascular disease therapy. Prog. Lipid Res. 50(4): 331-347. doi:10.1016/j.plipres.2011.04.002.PMID:21601592.
    • (2011) Prog. Lipid Res , vol.50 , Issue.4 , pp. 331-347
    • McLaren, J.E.1    Michael, D.R.2    Ashlin, T.G.3    Ramji, D.P.4
  • 68
    • 38049152517 scopus 로고    scopus 로고
    • Disruption of lipid metabolism in the liver of the pregnant rat fed folate-deficient and methyl donor-deficient diets
    • PMID:17697402
    • McNeil, C.J., Hay, S.M., Rucklidge, G.J., Reid, M., Duncan, G., Maloney, C.A., and Rees, W.D. 2008. Disruption of lipid metabolism in the liver of the pregnant rat fed folate-deficient and methyl donor-deficient diets. Br. J. Nutr. 99(2): 262-271. doi:10.1017/S0007114507798999.PMID:17697402.
    • (2008) Br. J. Nutr , vol.99 , Issue.2 , pp. 262-271
    • McNeil, C.J.1    Hay, S.M.2    Rucklidge, G.J.3    Reid, M.4    Duncan, G.5    Maloney, C.A.6    Rees, W.D.7
  • 69
    • 84875844656 scopus 로고    scopus 로고
    • Folate, alcohol, and liver disease
    • PMID:23136133
    • Medici, V., and Halsted, C.H. 2013. Folate, alcohol, and liver disease. Mol. Nutr. Food Res. 57(4): 596-606. doi:10.1002/mnfr.201200077.PMID:23136133.
    • (2013) Mol. Nutr. Food Res , vol.57 , Issue.4 , pp. 596-606
    • Medici, V.1    Halsted, C.H.2
  • 70
    • 34848911647 scopus 로고    scopus 로고
    • DNA methylation: The nuts and bolts of repression
    • PMID: 17708532
    • Miranda, T.B., and Jones, P.A. 2007. DNA methylation: the nuts and bolts of repression. J. Cell. Physiol. 213(2): 384-390. doi:10.1002/jcp.21224.PMID:17708532.
    • (2007) J. Cell. Physiol , vol.213 , Issue.2 , pp. 384-390
    • Miranda, T.B.1    Jones, P.A.2
  • 71
    • 12444260644 scopus 로고    scopus 로고
    • Body mass index and serum folate in childbearing age women
    • PMID:15648596
    • Mojtabai, R. 2004. Body mass index and serum folate in childbearing age women. Eur. J. Epidemiol. 19(11): 1029-1036. doi:10.1007/s10654-004-2253-z.PMID:15648596.
    • (2004) Eur. J. Epidemiol , vol.19 , Issue.11 , pp. 1029-1036
    • Mojtabai, R.1
  • 72
    • 57649214103 scopus 로고    scopus 로고
    • Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)
    • PMID:18824034
    • Musso, G., Gambino, R., and Cassader, M. 2009. Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD). Prog. Lipid Res. 48(1): 1-26. doi:10.1016/j.plipres.2008.08.001.PMID:18824034.
    • (2009) Prog. Lipid Res , vol.48 , Issue.1 , pp. 1-26
    • Musso, G.1    Gambino, R.2    Cassader, M.3
  • 73
    • 84958673442 scopus 로고    scopus 로고
    • Epigenetic alterations in human liver from subjects with type 2 diabetes in parallel with reduced folate levels
    • PMID:26418287
    • Nilsson, E., Matte, A., Perfilyev, A., de Mello, V.D., Käkelä, P., Pihlajamäki, J., and Ling, C. 2015. Epigenetic alterations in human liver from subjects with type 2 diabetes in parallel with reduced folate levels. J. Clin. Endocrinol. Metab. 100(11): E1491-E1501. doi:10.1210/jc.2015-3204.PMID:26418287.
    • (2015) J. Clin. Endocrinol. Metab , vol.100 , Issue.11 , pp. E1491-E1501
    • Nilsson, E.1    Matte, A.2    Perfilyev, A.3    De Mello, V.D.4    Käkelä, P.5    Pihlajamäki, J.6    Ling, C.7
  • 74
    • 0038159461 scopus 로고    scopus 로고
    • A gender-specific role for phosphatidylethanolamine N-methyltransferase-derived phosphatidylcholine in the regulation of plasma high density and very low density lipoproteins in mice
    • PMID:12668679
    • Noga, A.A., and Vance, D.E. 2003. A gender-specific role for phosphatidylethanolamine N-methyltransferase-derived phosphatidylcholine in the regulation of plasma high density and very low density lipoproteins in mice. J. Biol. Chem. 278(24): 21851-21859. doi:10.1074/jbc.M301982200.PMID:12668679.
    • (2003) J. Biol. Chem , vol.278 , Issue.24 , pp. 21851-21859
    • Noga, A.A.1    Vance, D.E.2
  • 75
    • 84930815604 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: Update on pathogenesis, diagnosis, treatment and the role of S-adenosylmethionine
    • Noureddin, M., Mato, J.M., and Lu, S.C. 2015. Nonalcoholic fatty liver disease: update on pathogenesis, diagnosis, treatment and the role of S-adenosylmethionine. Exp. Biol. Med. 240(6): 809-820. doi:10.1177/1535370215579161.
    • (2015) Exp. Biol. Med , vol.240 , Issue.6 , pp. 809-820
    • Noureddin, M.1    Mato, J.M.2    Lu, S.C.3
  • 76
    • 0015131860 scopus 로고
    • Folate analogues in normal mixed diets
    • PMID:5122667
    • Perry, J. 1971. Folate analogues in normal mixed diets. Br. J. Haematol. 21(4): 435-441. doi:10.1111/j.1365-2141.1971.tb02704.x.PMID:5122667.
    • (1971) Br. J. Haematol , vol.21 , Issue.4 , pp. 435-441
    • Perry, J.1
  • 77
    • 77954516516 scopus 로고    scopus 로고
    • Folic acid and L-5-methyltetrahydrofolate: Comparison of clinical pharmacokinetics and pharmacodynamics
    • PMID:20608755
    • Pietrzik, K., Bailey, L., and Shane, B. 2010. Folic acid and L-5-methyltetrahydrofolate: comparison of clinical pharmacokinetics and pharmacodynamics. Clin. Pharmacokinet. 49(8): 535-548. doi:10.2165/11532990-000000000-00000.PMID:20608755.
    • (2010) Clin. Pharmacokinet , vol.49 , Issue.8 , pp. 535-548
    • Pietrzik, K.1    Bailey, L.2    Shane, B.3
  • 78
    • 77951170478 scopus 로고    scopus 로고
    • Mitochondrial C1-tetrahydrofolate synthase (MTHFD1L) supports the flow of mitochondrial one-carbon units into the methyl cycle in embryos
    • PMID:19948730
    • Pike, S.T., Rajendra, R., Artzt, K., and Appling, D.R. 2010. Mitochondrial C1-tetrahydrofolate synthase (MTHFD1L) supports the flow of mitochondrial one-carbon units into the methyl cycle in embryos. J. Biol. Chem. 285(7): 4612-4620. doi:10.1074/jbc.M109.079855.PMID:19948730.
    • (2010) J. Biol. Chem , vol.285 , Issue.7 , pp. 4612-4620
    • Pike, S.T.1    Rajendra, R.2    Artzt, K.3    Appling, D.R.4
  • 79
    • 84856104213 scopus 로고    scopus 로고
    • Naringin ameliorates metabolic syndrome by activating AMP-activated protein kinase in mice fed a high-fat diet
    • PMID:22198281
    • Pu, P., Gao, D.M., Mohamed, S., Chen, J., Zhang, J., Zhou, X.Y., et al. 2012. Naringin ameliorates metabolic syndrome by activating AMP-activated protein kinase in mice fed a high-fat diet. Arch. Biochem. Biophys. 518(1): 61-70. doi:10.1016/j.abb.2011.11.026.PMID:22198281.
    • (2012) Arch. Biochem. Biophys , vol.518 , Issue.1 , pp. 61-70
    • Pu, P.1    Gao, D.M.2    Mohamed, S.3    Chen, J.4    Zhang, J.5    Zhou, X.Y.6
  • 80
    • 33751244559 scopus 로고    scopus 로고
    • Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption
    • PMID:17129779
    • Qiu, A., Jansen, M., Sakaris, A., Min, S.H., Chattopadhyay, S., Tsai, E., et al. 2006. Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption. Cell, 127(5): 917-928. doi:10.1016/j.cell.2006.09.041.PMID:17129779.
    • (2006) Cell , vol.127 , Issue.5 , pp. 917-928
    • Qiu, A.1    Jansen, M.2    Sakaris, A.3    Min, S.H.4    Chattopadhyay, S.5    Tsai, E.6
  • 82
    • 0030985350 scopus 로고    scopus 로고
    • Disposition of leucovorin and its metabolites in dietary folic acid-deplete mice-comparison between tumor, liver, and plasma
    • PMID:9182833
    • Raghunathan, K., Schmitz, J.C., and Priest, D.G. 1997. Disposition of leucovorin and its metabolites in dietary folic acid-deplete mice-comparison between tumor, liver, and plasma. Cancer Chemother. Pharmacol. 40(2): 126-130. doi:10.1007/s002800050636.PMID:9182833.
    • (1997) Cancer Chemother. Pharmacol , vol.40 , Issue.2 , pp. 126-130
    • Raghunathan, K.1    Schmitz, J.C.2    Priest, D.G.3
  • 83
    • 84655169624 scopus 로고    scopus 로고
    • Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis
    • Rolo, A.P., Teodoro, J.S., and Palmeira, C.M. 2012. Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis. Free Radical Biol. Med. 52(1): 59-69. doi:10.1016/j.freeradbiomed.2011.10.003.
    • (2012) Free Radical Biol. Med , vol.52 , Issue.1 , pp. 59-69
    • Rolo, A.P.1    Teodoro, J.S.2    Palmeira, C.M.3
  • 84
    • 0026356764 scopus 로고
    • Bacterially synthesized folate in rat large intestine is incorporated into host tissue folyl polyglutamates
    • PMID:1941259
    • Rong, N., Selhub, J., Goldin, B.R., and Rosenberg, I.H. 1991. Bacterially synthesized folate in rat large intestine is incorporated into host tissue folyl polyglutamates. J. Nutr. 121(12): 1955-1959. PMID:1941259.
    • (1991) J. Nutr , vol.121 , Issue.12 , pp. 1955-1959
    • Rong, N.1    Selhub, J.2    Goldin, B.R.3    Rosenberg, I.H.4
  • 85
    • 0035856949 scopus 로고    scopus 로고
    • Insulin signalling and the regulation of glucose and lipid metabolism
    • PMID:11742412
    • Saltiel, A.R., and Kahn, C.R. 2001. Insulin signalling and the regulation of glucose and lipid metabolism. Nature, 414(6865): 799-806. doi:10.1038/414799a.PMID:11742412.
    • (2001) Nature , vol.414 , Issue.6865 , pp. 799-806
    • Saltiel, A.R.1    Kahn, C.R.2
  • 86
    • 0035084699 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities
    • PMID:11266382
    • Sanyal, A.J., Campbell-Sargent, C., Mirshahi, F., Rizzo, W.B., Contos, M.J., Sterling, R.K., et al. 2001. Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities. Gastroenterology, 120(5): 1183-1192. doi:10.1053/gast.2001.23256.PMID:11266382.
    • (2001) Gastroenterology , vol.120 , Issue.5 , pp. 1183-1192
    • Sanyal, A.J.1    Campbell-Sargent, C.2    Mirshahi, F.3    Rizzo, W.B.4    Contos, M.J.5    Sterling, R.K.6
  • 87
    • 84863133957 scopus 로고    scopus 로고
    • Folic acid supplementation attenuates high fat diet induced hepatic oxidative stress via regulation of NADPH oxidase
    • PMID:22309437
    • Sarna, L.K., Wu, N., Wang, P., Hwang, S.Y., Siow, Y.L., and O, K. 2012. Folic acid supplementation attenuates high fat diet induced hepatic oxidative stress via regulation of NADPH oxidase. Can. J. Physiol. Pharmacol. 90(2): 155-165. doi:10.1139/y11-124.PMID:22309437.
    • (2012) Can. J. Physiol. Pharmacol , vol.90 , Issue.2 , pp. 155-165
    • Sarna, L.K.1    Wu, N.2    Wang, P.3    Hwang, S.Y.4    Siow, Y.L.5
  • 88
    • 0032813088 scopus 로고    scopus 로고
    • Repair of DNA damage in mitochondria
    • PMID:10486590
    • Sawyer, D.E., and Van Houten, B. 1999. Repair of DNA damage in mitochondria. Mutat. Res. 434(3): 161-176. doi:10.1016/S0921-8777(99)00027-0.PMID:10486590.
    • (1999) Mutat. Res , vol.434 , Issue.3 , pp. 161-176
    • Sawyer, D.E.1    Van Houten, B.2
  • 89
    • 84880419922 scopus 로고    scopus 로고
    • Non-alcoholic steatohepatitis: Pathogenesis and novel therapeutic approaches
    • PMID:23855299
    • Schuppan, D., and Schattenberg, J.M. 2013. Non-alcoholic steatohepatitis: pathogenesis and novel therapeutic approaches. J. Gastroenterol. Hepatol. 28(S1): 68-76. doi:10.1111/jgh.12212.PMID:23855299.
    • (2013) J. Gastroenterol. Hepatol , vol.28 , Issue.S1 , pp. 68-76
    • Schuppan, D.1    Schattenberg, J.M.2
  • 90
    • 12444341903 scopus 로고    scopus 로고
    • Localization of the PE methylation pathway and SR-BI to the canalicular membrane: Evidence for apical PC biosynthesis that may promote biliary excretion of phospholipid and cholesterol
    • PMID:12810817
    • Sehayek, E., Wang, R., Ono, J.G., Zinchuk, V.S., Duncan, E.M., Shefer, S., et al. 2003. Localization of the PE methylation pathway and SR-BI to the canalicular membrane: evidence for apical PC biosynthesis that may promote biliary excretion of phospholipid and cholesterol. J. Lipid Res. 44(9): 1605-1613. doi:10.1194/jlr.M200488-JLR200.PMID:12810817.
    • (2003) J. Lipid Res , vol.44 , Issue.9 , pp. 1605-1613
    • Sehayek, E.1    Wang, R.2    Ono, J.G.3    Zinchuk, V.S.4    Duncan, E.M.5    Shefer, S.6
  • 91
    • 0035991444 scopus 로고    scopus 로고
    • In situ detection of lipid peroxidation and oxidative DNA damage in nonalcoholic fatty liver diseases
    • PMID:12076862
    • Seki, S., Kitada, T., Yamada, T., Sakaguchi, H., Nakatani, K., and Wakasa, K. 2002. In situ detection of lipid peroxidation and oxidative DNA damage in nonalcoholic fatty liver diseases. J. Hepatol. 37(1): 56-62. doi:10.1016/S0168-8278(02)00073-9.PMID:12076862.
    • (2002) J. Hepatol , vol.37 , Issue.1 , pp. 56-62
    • Seki, S.1    Kitada, T.2    Yamada, T.3    Sakaguchi, H.4    Nakatani, K.5    Wakasa, K.6
  • 92
    • 34247860634 scopus 로고    scopus 로고
    • Gamma-Glutamyl hydrolase, not glutamate carboxypeptidase II, hydrolyzes dietary folate in rat small intestine
    • PMID:17449573
    • Shafizadeh, T.B., and Halsted, C.H. 2007. gamma-Glutamyl hydrolase, not glutamate carboxypeptidase II, hydrolyzes dietary folate in rat small intestine. J. Nutr. 137(5): 1149-1153. PMID:17449573.
    • (2007) J. Nutr , vol.137 , Issue.5 , pp. 1149-1153
    • Shafizadeh, T.B.1    Halsted, C.H.2
  • 93
    • 0017104055 scopus 로고
    • Subcellular localization of gamma-glutamyl carboxypeptidase and of folates
    • PMID:186108
    • Shin, Y.S., Chan, C., Vidal, A.J., Brody, T., and Stokstad, E.L. 1976. Subcellular localization of gamma-glutamyl carboxypeptidase and of folates. Biochim. Biophys. Acta, Gen. Subj. 444(3): 794-801. doi:10.1016/0304-4165(76)90326-3.PMID:186108.
    • (1976) Biochim. Biophys. Acta, Gen. Subj , vol.444 , Issue.3 , pp. 794-801
    • Shin, Y.S.1    Chan, C.2    Vidal, A.J.3    Brody, T.4    Stokstad, E.L.5
  • 94
    • 84947206658 scopus 로고    scopus 로고
    • Folic acid supplementation during high-fat diet feeding restores AMPK activation via an AMP-LKB1-dependent mechanism
    • PMID:26400185
    • Sid, V., Wu, N., Sarna, L.K., Siow, Y.L., House, J.D., and O, K. 2015. Folic acid supplementation during high-fat diet feeding restores AMPK activation via an AMP-LKB1-dependent mechanism. Am. J. Physiol. Regul. Integr. Comp. Physiol. 309(10): R1215-R1225. doi:10.1152/ajpregu.00260.2015.PMID:26400185.
    • (2015) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.309 , Issue.10 , pp. R1215-R1225
    • Sid, V.1    Wu, N.2    Sarna, L.K.3    Siow, Y.L.4    House, J.D.5
  • 95
    • 33746476301 scopus 로고    scopus 로고
    • Effect of short-term folic acid supplementation on insulin sensitivity and inflammatory markers in overweight subjects
    • Solini, A., Santini, E., and Ferrannini, E. 2006. Effect of short-term folic acid supplementation on insulin sensitivity and inflammatory markers in overweight subjects. Int. J. Obes. Relat. Metab. Disord. 30(8): 1197-1202. doi:10.1038/sj.ijo.0803265.
    • (2006) Int. J. Obes. Relat. Metab. Disord , vol.30 , Issue.8 , pp. 1197-1202
    • Solini, A.1    Santini, E.2    Ferrannini, E.3
  • 96
    • 0018748110 scopus 로고
    • Kinetics of the normal folate enterohepatic cycle
    • PMID:447863
    • Steinberg, S.E., Campbell, C.L., and Hillman, R.S. 1979. Kinetics of the normal folate enterohepatic cycle. J. Clin. Invest. 64(1): 83-88. doi:10.1172/JCI109467.PMID:447863.
    • (1979) J. Clin. Invest , vol.64 , Issue.1 , pp. 83-88
    • Steinberg, S.E.1    Campbell, C.L.2    Hillman, R.S.3
  • 97
    • 3142774934 scopus 로고    scopus 로고
    • Physiology of folate and vitamin B12 in health and disease
    • Stover, P.J. 2004. Physiology of folate and vitamin B12 in health and disease. Nutr. Rev. 62: S3-S12. doi:10.1111/j.1753-4887.2004.tb00070.x.
    • (2004) Nutr. Rev , vol.62 , pp. SS3-S12
    • Stover, P.J.1
  • 98
    • 83455213193 scopus 로고    scopus 로고
    • Trafficking of intracellular folates
    • PMID:22332074
    • Stover, P.J., and Field, M.S. 2011. Trafficking of intracellular folates. Adv. Nutr. 2(4): 325-331. doi:10.3945/an.111.000596.PMID:22332074.
    • (2011) Adv. Nutr , vol.2 , Issue.4 , pp. 325-331
    • Stover, P.J.1    Field, M.S.2
  • 99
    • 84896722464 scopus 로고    scopus 로고
    • Adaptive immune responses triggered by oxidative stress contribute to hepatic inflammation in NASH
    • PMID:24115128
    • Sutti, S., Jindal, A., Locatelli, I., Vacchiano, M., Gigliotti, L., Bozzola, C., and Albano, E. 2014. Adaptive immune responses triggered by oxidative stress contribute to hepatic inflammation in NASH. Hepatology, 59(3): 886-897. doi:10.1002/hep.26749.PMID:24115128.
    • (2014) Hepatology , vol.59 , Issue.3 , pp. 886-897
    • Sutti, S.1    Jindal, A.2    Locatelli, I.3    Vacchiano, M.4    Gigliotti, L.5    Bozzola, C.6    Albano, E.7
  • 100
    • 84861738395 scopus 로고    scopus 로고
    • Animal models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
    • PMID:22654421
    • Takahashi, Y., Soejima, Y., and Fukusato, T. 2012. Animal models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. World J. Gastroenterol. 18(19): 2300-2308. doi:10.3748/wjg.v18.i19.2300.PMID:22654421.
    • (2012) World J. Gastroenterol , vol.18 , Issue.19 , pp. 2300-2308
    • Takahashi, Y.1    Soejima, Y.2    Fukusato, T.3
  • 101
    • 77955616558 scopus 로고    scopus 로고
    • Compartmentalization of mammalian folate-mediated one-carbon metabolism
    • PMID:20645850
    • Tibbetts, A.S., and Appling, D.R. 2010. Compartmentalization of mammalian folate-mediated one-carbon metabolism. Annu. Rev. Nutr. 30: 57-81. doi:10.1146/annurev.nutr.012809.104810.PMID:20645850.
    • (2010) Annu. Rev. Nutr , vol.30 , pp. 57-81
    • Tibbetts, A.S.1    Appling, D.R.2
  • 102
    • 78049522194 scopus 로고    scopus 로고
    • Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis
    • PMID:21038418
    • Tilg, H., and Moschen, A.R. 2010. Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis. Hepatology, 52(5): 1836-1846. doi:10.1002/hep.24001.PMID:21038418.
    • (2010) Hepatology , vol.52 , Issue.5 , pp. 1836-1846
    • Tilg, H.1    Moschen, A.R.2
  • 103
    • 0019528301 scopus 로고
    • Protein, iron, and folate status of patients prior to and following surgery for morbid obesity
    • PMID:7217567
    • Updegraff, T.A., and Neufeld, N.J. 1981. Protein, iron, and folate status of patients prior to and following surgery for morbid obesity. J. Am. Diet. Assoc. 78(2): 135-140. PMID:7217567.
    • (1981) J. Am. Diet. Assoc , vol.78 , Issue.2 , pp. 135-140
    • Updegraff, T.A.1    Neufeld, N.J.2
  • 104
    • 33845490856 scopus 로고    scopus 로고
    • The role of insulin resistance in nonalcoholic fatty liver disease
    • PMID:16968800
    • Utzschneider, K.M., and Kahn, S.E. 2006. The role of insulin resistance in nonalcoholic fatty liver disease. J. Clin. Endocrinol. Metab. 91(12): 4753-4761. doi:10.1210/jc.2006-0587.PMID:16968800.
    • (2006) J. Clin. Endocrinol. Metab , vol.91 , Issue.12 , pp. 4753-4761
    • Utzschneider, K.M.1    Kahn, S.E.2
  • 105
    • 12144291550 scopus 로고    scopus 로고
    • Oxidative stress-related parameters in the liver of non-alcoholic fatty liver disease patients
    • PMID:14556645
    • Videla, L.A., Rodrigo, R., Orellana, M., Fernandez, V., Tapia, G., Quiñones, L., et al. 2004. Oxidative stress-related parameters in the liver of non-alcoholic fatty liver disease patients. Clin. Sci. 106(3): 261-268. doi:10.1042/CS20030285.PMID:14556645.
    • (2004) Clin. Sci , vol.106 , Issue.3 , pp. 261-268
    • Videla, L.A.1    Rodrigo, R.2    Orellana, M.3    Fernandez, V.4    Tapia, G.5    Quiñones, L.6
  • 106
    • 23044512117 scopus 로고    scopus 로고
    • Endothelial dysfunction and cardiovascular risk profile in nonalcoholic fatty liver disease
    • PMID:15981216
    • Villanova, N., Moscatiello, S., Ramilli, S., Bugianesi, E., Magalotti, D., Vanni, E., et al. 2005. Endothelial dysfunction and cardiovascular risk profile in nonalcoholic fatty liver disease. Hepatology, 42(2): 473-480. doi:10.1002/hep.20781.PMID:15981216.
    • (2005) Hepatology , vol.42 , Issue.2 , pp. 473-480
    • Villanova, N.1    Moscatiello, S.2    Ramilli, S.3    Bugianesi, E.4    Magalotti, D.5    Vanni, E.6
  • 107
    • 84894183663 scopus 로고    scopus 로고
    • The intestinal absorption of folates
    • PMID:24512081
    • Visentin, M., Diop-Bove, N., Zhao, R., and Goldman, I.D. 2014. The intestinal absorption of folates. Annu. Rev. Physiol. 76: 251-274. doi:10.1146/annurevphysiol-020911-153251.PMID:24512081.
    • (2014) Annu. Rev. Physiol , vol.76 , pp. 251-274
    • Visentin, M.1    Diop-Bove, N.2    Zhao, R.3    Goldman, I.D.4
  • 108
    • 0037164375 scopus 로고    scopus 로고
    • Homocysteine and cardiovascular disease: Evidence on causality from a meta-analysis
    • PMID:12446535
    • Wald, D.S., Law, M., and Morris, J.K. 2002. Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. BMJ, 325(7374): 1202. doi:10.1136/bmj.325.7374.1202.PMID:12446535.
    • (2002) BMJ , vol.325 , Issue.7374 , pp. 1202
    • Wald, D.S.1    Law, M.2    Morris, J.K.3
  • 109
    • 14944384253 scopus 로고    scopus 로고
    • Folic acid reverses hyper-responsiveness of LPS-induced chemokine secretion from monocytes in patients with hyperhomocysteinemia
    • PMID:15777559
    • Wang, G., Dai, J., Mao, J., Zeng, X., Yang, X., and Wang, X. 2005. Folic acid reverses hyper-responsiveness of LPS-induced chemokine secretion from monocytes in patients with hyperhomocysteinemia. Atherosclerosis, 179(2): 395-402. doi:10.1016/j.atherosclerosis.2004.10.033.PMID:15777559.
    • (2005) Atherosclerosis , vol.179 , Issue.2 , pp. 395-402
    • Wang, G.1    Dai, J.2    Mao, J.3    Zeng, X.4    Yang, X.5    Wang, X.6
  • 110
    • 85030112429 scopus 로고    scopus 로고
    • WHO. 2016. http://www.who.int/mediacentre/factsheets/fs311/en/.
    • (2016)
  • 111
    • 33746854283 scopus 로고    scopus 로고
    • Hyperhomocysteinemia induces liver injury in rat: Protective effect of folic acid supplementation
    • PMID:16837172
    • Woo, C.W., Prathapasinghe, G.A., Siow, Y.L., and O, K. 2006. Hyperhomocysteinemia induces liver injury in rat: protective effect of folic acid supplementation. Biochim. Biophys. Acta, Mol. Basis Dis. 1762(7): 656-665. doi:10.1016/j.bbadis.2006.05.012.PMID:16837172.
    • (2006) Biochim. Biophys. Acta, Mol. Basis Dis , vol.1762 , Issue.7 , pp. 656-665
    • Woo, C.W.1    Prathapasinghe, G.A.2    Siow, Y.L.3
  • 112
    • 34748912412 scopus 로고    scopus 로고
    • Folic acid metabolism in human subjects revisited: Potential implications for proposed mandatory folic acid fortification in the UK
    • PMID:17617936
    • Wright, A.J., Dainty, J.R., and Finglas, P.M. 2007. Folic acid metabolism in human subjects revisited: potential implications for proposed mandatory folic acid fortification in the UK. Br. J. Nutr. 98(4): 667-675. doi:10.1017/S0007114507777140.PMID:17617936.
    • (2007) Br. J. Nutr , vol.98 , Issue.4 , pp. 667-675
    • Wright, A.J.1    Dainty, J.R.2    Finglas, P.M.3
  • 113
    • 59849093173 scopus 로고    scopus 로고
    • Membrane transporters and folate homeostasis: Intestinal absorption and transport into systemic compartments and tissues
    • PMID:19173758
    • Zhao, R., Matherly, L.H., and Goldman, I.D. 2009. Membrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues. Expert Rev. Mol. Med. 11: e4. doi:10.1017/S1462399409000969.PMID:19173758.
    • (2009) Expert Rev. Mol. Med , vol.11
    • Zhao, R.1    Matherly, L.H.2    Goldman, I.D.3
  • 114
    • 79960481261 scopus 로고    scopus 로고
    • Mechanisms of membrane transport of folates into cells and across epithelia
    • PMID:21568705
    • Zhao, R., Diop-Bove, N., Visentin, M., and Goldman, I.D. 2011. Mechanisms of membrane transport of folates into cells and across epithelia. Annu. Rev. Nutr. 31: 177-201. doi:10.1146/annurev-nutr-072610-145133.PMID:21568705.
    • (2011) Annu. Rev. Nutr , vol.31 , pp. 177-201
    • Zhao, R.1    Diop-Bove, N.2    Visentin, M.3    Goldman, I.D.4
  • 115
    • 69849104511 scopus 로고    scopus 로고
    • Lack of phosphatidylethanolamine N-methyltransferase alters plasma VLDL phospholipids and attenuates atherosclerosis in mice
    • PMID: 19520976
    • Zhao, Y., Su, B., Jacobs, R.L., Kennedy, B., Francis, G.A., Waddington, E., et al. 2009. Lack of phosphatidylethanolamine N-methyltransferase alters plasma VLDL phospholipids and attenuates atherosclerosis in mice. Arterioscler., Thromb., Vasc. Biol. 29(9): 1349-1355. doi:10.1161/ATVBAHA.109.188672.PMID:19520976.
    • (2009) Arterioscler., Thromb., Vasc. Biol , vol.29 , Issue.9 , pp. 1349-1355
    • Zhao, Y.1    Su, B.2    Jacobs, R.L.3    Kennedy, B.4    Francis, G.A.5    Waddington, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.