Folic acid supplementation during high-fat diet feeding restores AMPK activation via an AMP-LKB1-dependent mechanism

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 309, Issue 10, 2015, Pages R1215-R1225

  Sid, Victoria ^a,b   Wu, Nan ^a,b   Sarna, Lindsei K ^a,c   Siow, Yaw L ^a,b,d   House, James D ^c   Karmin, O ^a,b,c  

^a ST BONIFACE GENERAL HOSPITAL   (Canada)

^b Department of Physiology and Pathophysiology ^*  (Canada)

^c UNIVERSITY OF MANITOBA   (Canada)

^d AGRICULTURE AND AGRI FOOD CANADA   (Canada)

Author keywords

AMP; AMP activated protein kinase; Folic acid; Liver kinase B1; Nonalcoholic fatty liver disease

Indexed keywords

5 METHYLTETRAHYDROFOLIC ACID; ADENOSINE PHOSPHATE; CHOLESTEROL; FOLIC ACID; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PALMITIC ACID; PROTEIN KINASE LKB1; FAT INTAKE; PROTEIN SERINE THREONINE KINASE; STK11 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHOLESTEROL LIVER LEVEL; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENZYME ACTIVATION; GLUCOSE BLOOD LEVEL; HEPG2 CELL LINE; HUMAN; HUMAN CELL; HYPERGLYCEMIA; IMMUNOBLOTTING; IN VIVO STUDY; LIPID DIET; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING; ADMINISTRATION AND DOSAGE; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; DIETARY SUPPLEMENT; DRUG EFFECTS; FAT INTAKE; GENE EXPRESSION REGULATION; GENETICS; HEP-G2 CELL LINE; METABOLISM; WEIGHT GAIN;

ADENOSINE MONOPHOSPHATE; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; DIETARY FATS; DIETARY SUPPLEMENTS; ENZYME ACTIVATION; FOLIC ACID; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEP G2 CELLS; HUMANS; MALE; MICE; MICE, INBRED C57BL; PROTEIN-SERINE-THREONINE KINASES; WEIGHT GAIN;

EID: 84947206658     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00260.2015     Document Type: Article

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