The extremely slow and variable activity of dihydrofolate reductase in human liver and its implications for high folic acid intake

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 36, 2009, Pages 15424-15429

  Bailey, Steven W ^a   Ayling, June E ^a  

^a UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

Author keywords

Folate; Nutrition; Provitamin utilization; Unmetabolized folic acid; Vitamin supplements

Indexed keywords

DIHYDROFOLATE REDUCTASE; FOLIC ACID; TETRAHYDROFOLIC ACID;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; HUMAN VERSUS ANIMAL COMPARISON; LIVER; NONHUMAN; ORGAN DONOR; PH; PRIORITY JOURNAL; RAT;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FOLIC ACID; HUMANS; LIVER; MOLECULAR STRUCTURE; RATS; SPECIES SPECIFICITY; TETRAHYDROFOLATE DEHYDROGENASE; TETRAHYDROFOLATES;

RATTUS;

EID: 70349324816     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0902072106     Document Type: Article

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