Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Nature Genetics

Volumn 49, Issue 9, 2017, Pages 1373-1384

  Sims, Rebecca ^a   Van Der Lee, Sven J ^b   Naj, Adam C ^c   Bellenguez, Céline ^d,e,f   Badarinarayan, Nandini ^a   Jakobsdottir, Johanna ^g   Kunkle, Brian W ^h   Boland, Anne ⁱ   Raybould, Rachel ^a   Bis, Joshua C ^j   Martin, Eden R ^h   Grenier Boley, Benjamin ^d,e,f   Heilmann Heimbach, Stefanie ^k   Chouraki, Vincent ^l,m   Kuzma, Amanda B ^c   Sleegers, Kristel ^n,o   Vronskaya, Maria ^a   Ruiz, Agustin ^p   Graham, Robert R ^q   Olaso, Robert ⁱ   Hoffmann, Per ^k,r   Grove, Megan L ^s   Vardarajan, Badri N ^t,u   Hiltunen, Mikko ^v,w   Nöthen, Markus M ^k   White, Charles C ^x   Hamilton Nelson, Kara L ^h   Epelbaum, Jacques ^y   Maier, Wolfgang ^k,z   Choi, Seung Hoan ^l,aa   Beecham, Gary W ^h   Dulary, Cécile ⁱ   Herms, Stefan ^k,r   Smith, Albert V ^g,ab   Funk, Cory C ^ac   Derbois, Céline ⁱ   Forstner, Andreas J ^k   Ahmad, Shahzad ^b   Li, Hongdong ^ac   Bacq, Delphine ⁱ   Harold, Denise ^ad   Satizabal, Claudia L ^l,m   Valladares, Otto ^c   Squassina, Alessio ^ae   Thomas, Rhodri ^a   Brody, Jennifer A ^j   Qu, Liming ^c   Sánchez Juan, Pascual ^af   Morgan, Taniesha ^a   Wolters, Frank J ^b   Zhao, Yi ^c   Garcia, Florentino Sanchez ^ag   Denning, Nicola ^a   Fornage, Myriam ^ah   Malamon, John ^c   Naranjo, Maria Candida Deniz ^ag   Majounie, Elisa ^a   Mosley, Thomas H ^ai   Dombroski, Beth ^c   Wallon, David ^aj,ak   Lupton, Michelle K ^al,am   Dupuis, Josée ^aa   Whitehead, Patrice ^h   Fratiglioni, Laura ^an,ao   Medway, Christopher ^ap   Jian, Xueqiu ^ah   Mukherjee, Shubhabrata ^j   Keller, Lina ^ao   Brown, Kristelle ^ap   Lin, Honghuang ^l   Cantwell, Laura B ^c   Panza, Francesco ^aq   McGuinness, Bernadette ^ar   Moreno Grau, Sonia ^p   Burgess, Jeremy D ^as   Solfrizzi, Vincenzo ^aq   Proitsi, Petra ^al   Adams, Hieab H ^b   Allen, Mariet ^as   Seripa, Davide ^at   Pastor, Pau ^au   Cupples, L Adrienne ^m,aa   Price, Nathan D ^ac   Hannequin, Didier ^ak,av   Frank García, Ana ^aw,ax   Levy, Daniel ^l,m,ay   Chakrabarty, Paramita ^az   Caffarra, Paolo ^ba,bb   Giegling, Ina ^bc   Beiser, Alexa S ^m,aa   Giedraitis, Vilmantas ^bd   Hampel, Harald ^be,bf,bg   Garcia, Melissa E ^bh   Wang, Xue ^as   Lannfelt, Lars ^bd   Mecocci, Patrizia ^au   Eiriksdottir, Gudny ^g   Crane, Paul K ^j   Pasquier, Florence ^bi,bj   Boccardi, Virginia ^au   Henández, Isabel ^p   Barber, Robert C ^bk   Scherer, Martin ^bl   Tarraga, Lluis ^p   Adams, Perrie M ^bm   Leber, Markus ^bn   Chen, Yuning ^aa   Albert, Marilyn S ^bo   Riedel Heller, Steffi ^bp   Emilsson, Valur ^g,bq   Beekly, Duane ^br   Braae, Anne ^ap   Schmidt, Reinhold ^bs   Blacker, Deborah ^bt,bu   Masullo, Carlo ^bv   Schmidt, Helena ^bs   Doody, Rachelle S ^bw   Spalletta, Gianfranco ^bx   Jr, W T Longstreth ^br   Fairchild, Thomas J ^bk   Bossù, Paola ^bx   Lopez, Oscar L ^by   Frosch, Matthew P ^bu   Sacchinelli, Eleonora ^bx   Ghetti, Bernardino ^bz   Yang, Qiong ^aa   Huebinger, Ryan M ^ca   Jessen, Frank ^k,z,bn   Li, Shuo ^aa   Kamboh, M Ilyas ^by,cb   Morris, John C ^cc   Sotolongo Grau, Oscar ^p   Katz, Mindy J ^cd   Corcoran, Chris ^ce   Dunstan, Melanie ^a   Braddel, Amy ^a   Thomas, Charlene ^a   Meggy, Alun ^a   Marshall, Rachel ^a   Gerrish, Amy ^a   Chapman, Jade ^a   Aguilar, Miquel ^cf,cg   Taylor, Sarah ^a   Hill, Matt ^a   Fairén, Mònica Díez ^ax,cf   Hodges, Angela ^al   Vellas, Bruno ^ch   Soininen, Hilkka ^w   Kloszewska, Iwona ^ci   Daniilidou, Makrina ^cj   Uphill, James ^ck   Patel, Yogen ^al   Hughes, Joseph T ^al   Lord, Jenny ^ap   Turton, James ^ap   Hartmann, Annette M ^bc   Cecchetti, Roberta ^au   Fenoglio, Chiara ^cl   Serpente, Maria ^cl   Arcaro, Marina ^cl   Caltagirone, Carlo ^bx   Orfei, Maria Donata ^bx   Ciaramella, Antonio ^bx   Pichler, Sabrina ^cm   Mayhaus, Manuel ^cm   Gu, Wei ^cm   Lleó, Alberto ^ax,cn   Fortea, Juan ^ax,cn   Blesa, Rafael ^ax,cn   Barber, Imelda S ^ap   Brookes, Keeley ^ap   Cupidi, Chiara ^co   Maletta, Raffaele Giovanni ^co   Carrell, David ^j   Sorbi, Sandro ^cp,cq   Moebus, Susanne ^cr   Urbano, Maria ^at   Pilotto, Alberto ^at   Kornhuber, Johannes ^cs   Bosco, Paolo ^ct   Todd, Stephen ^ar   Craig, David ^ar   Johnston, Janet ^ar   Gill, Michael ^cu   Lawlor, Brian ^cu   Lynch, Aoibhinn ^cu   Fox, Nick C ^ck   Hardy, John ^ck   Albin, Roger L ^cv,cw,cx   Apostolova, Liana G ^bz,cx,cy   Arnold, Steven E ^c   Asthana, Sanjay ^cz,da   Atwood, Craig S ^cz,da   Baldwin, Clinton T ^l   Barnes, Lisa L ^db,dc   Barral, Sandra ^t,u   Beach, Thomas G ^dd   Becker, James T ^by   Bigio, Eileen H ^de   Bird, Thomas D ^br,df   Boeve, Bradley F ^dg   Bowen, James D ^dh   Boxer, Adam ^di   Burke, James R ^dj   Burns, Jeffrey M ^dk   Buxbaum, Joseph D ^dl   Cairns, Nigel J ^cc   Cao, Chuanhai ^dm   Carlson, Chris S ^dn   Carlsson, Cynthia M ^da   Carney, Regina M ^h   Carrasquillo, Minerva M ^as   Carroll, Steven L ^do   Diaz, Carolina Ceballos ^az   Chui, Helena C ^dp   Clark, David G ^do,dq   Cribbs, David H ^dr   Crocco, Elizabeth A ^h   Decarli, Charles ^ds   Dick, Malcolm ^dt   Duara, Ranjan ^du   Evans, Denis A ^dv   Faber, Kelley M ^bz   Fallon, Kenneth B ^dw   Fardo, David W ^dx   Farlow, Martin R ^bz   Ferris, Steven ^dy   Foroud, Tatiana M ^bz   Galasko, Douglas R ^dz   Gearing, Marla ^ea,eb   Geschwind, Daniel H ^ec   Gilbert, John R ^h   Graff Radford, Neill R ^as,ed   Green, Robert C ^x   Growdon, John H ^bu   Hamilton, Ronald L ^by   Harrell, Lindy E ^ee   Honig, Lawrence S ^t   Huentelman, Matthew J ^ef   Hulette, Christine M ^dj   Hyman, Bradley T ^bu   Jarvik, Gail P ^br   Abner, Erin ^eg   Jin, Lee Way ^ds   Jun, Gyungah ^l,eh   Karydas, Anna ^di   Kaye, Jeffrey A ^ei,ej   Kim, Ronald ^dr   Kowall, Neil W ^l   Kramer, Joel H ^ek   Laferla, Frank M ^dr   Lah, James J ^ea   Leverenz, James B ^el   Levey, Allan I ^ea   Li, Ge ^j,df   Lieberman, Andrew P ^cv   Lunetta, Kathryn L ^eh   Lyketsos, Constantine G ^bo   Marson, Daniel C ^ee   Martiniuk, Frank ^em   Mash, Deborah C ^h   Masliah, Eliezer ^dz,en   McCormick, Wayne C ^j   McCurry, Susan M ^br   McDavid, Andrew N ^dn   McKee, Ann C ^l   Mesulam, Marsel ^de   Miller, Bruce L ^di   Miller, Carol A ^dp   Miller, Joshua W ^ds   Murrell, Jill R ^bz   Myers, Amanda J ^h   O'Bryant, Sid ^eo   Olichney, John M ^ds   Pankratz, Vernon S ^ep   Parisi, Joseph E ^dg   Paulson, Henry L ^cv,cx   Perry, William ^h   Peskind, Elaine ^j   Pierce, Aimee ^dr   Poon, Wayne W ^dt   Potter, Huntington ^eq   Quinn, Joseph F ^ei,ej   Raj, Ashok ^dm   Raskind, Murray ^j   Reisberg, Barry ^dy,em   Reitz, Christiane ^t,u   Ringman, John M ^er   Roberson, Erik D ^ee   Rogaeva, Ekaterina ^es   Rosen, Howard J ^di   Rosenberg, Roger N ^ca   Sager, Mark A ^da   Saykin, Andrew J ^bz   Schneider, Julie A ^db,dc   Schneider, Lon S ^dp   Seeley, William W ^di   Smith, Amanda G ^dm   Sonnen, Joshua A ^br   Spina, Salvatore ^bz   Stern, Robert A ^l   Swerdlow, Russell H ^dk   Tanzi, Rudolph E ^bu   Thornton Wells, Tricia A ^et   Trojanowski, John Q ^c   Troncoso, Juan C ^bo   Van Deerlin, Vivianna M ^c   Van Eldik, Linda J ^dx   Vinters, Harry V ^er   Vonsattel, Jean Paul ^t   Weintraub, Sandra ^de   Welsh Bohmer, Kathleen A ^dj   Wilhelmsen, Kirk C ^eu   Williamson, Jennifer ^t   Wingo, Thomas S ^ea   Woltjer, Randall L ^ei   Wright, Clinton B ^h   Yu, Chang En ^j   Yu, Lei ^db,dc   Garzia, Fabienne ⁱ   Golamaully, Feroze ⁱ   Septier, Gislain ⁱ   Engelborghs, Sebastien ^o,ev   Vandenberghe, Rik ^ev,ew   De Deyn, Peter P ^o,ev   Fernadez, Carmen Muñoz ^ag   Benito, Yoland Aladro ^ag   Thonberg, Hakan ^an,ao   Forsell, Charlotte ^an,ao   Lilius, Lena ^an,ao   Kinhult Stählbom, Anne ^an,ao   Kilander, Lena ^bd   Brundin, Rosemarie ^bd   Concari, Letizia ^ba,bb   Helisalmi, Seppo ^v,w   Koivisto, Anne Maria ^v,w   Haapasalo, Annakaisa ^v,w   Dermecourt, Vincent ^bi   Fievet, Nathalie ^d,e,f,ex   Hanon, Olivier ^ex   Dufouil, Carole ^y,ey   Brice, Alexis ^bf,bg   Ritchie, Karen ^ez   Dubois, Bruno ^bg,fa   Himali, Jayanadra J ^l   Keene, C Dirk ^br   Tschanz, Joann ^ce   Fitzpatrick, Annette L ^j,br   Kukull, Walter A ^br   Norton, Maria ^ce   Aspelund, Thor ^g,bq   Larson, Eric B ^j,fb   Munger, Ron ^ce   Rotter, Jerome I ^fc   Lipton, Richard B ^cd   Bullido, María J ^aw,ax,fd   Hofman, Albert ^b   Montine, Thomas J ^br   Coto, Eliecer ^fe   Boerwinkle, Eric ^s,bw   Petersen, Ronald C ^dg   Alvarez, Victoria ^fe   Rivadeneira, Fernando ^b,ff   Reiman, Eric M ^ef,fg,fh,fi   Gallo, Maura ^co   O'Donnell, Christopher J ^m   Reisch, Joan S ^bm   Bruni, Amalia Cecilia ^co   Royall, Donald R ^fj   Dichgans, Martin ^z,fk   Sano, Mary ^dl   Galimberti, Daniela ^cl   St George Hyslop, Peter ^es,fl   Scarpini, Elio ^cl   Tsuang, Debby W ^j,df   Mancuso, Michelangelo ^fm   Bonuccelli, Ubaldo ^fm   Winslow, Ashley R ^fn   Daniele, Antonio ^bv   Wu, Chuang Kuo ^fo   Peters, Oliver ^fp   Nacmias, Benedetta ^cp,cq   Riemenschneider, Matthias ^cm   Heun, Reinhard ^k   Brayne, Carol ^fq   Rubinsztein, David C ^fl   Bras, Jose ^ck,fr   Guerreiro, Rita ^ck,fr   Al Chalabi, Ammar ^al   Shaw, Christopher E ^al   Collinge, John ^ck   Tsolaki, Magda ^ft   Clarimón, Jordi ^ax,cn   Sussams, Rebecca ^fu   Lovestone, Simon ^fv   O'Donovan, Michael C ^a   Owen, Michael J ^a   Behrens, Timothy W ^q   Mead, Simon ^ck   Uitterlinden, Andre G ^b,ck,cl   Holmes, Clive ^df   Cruchaga, Carlos ^cc   Ingelsson, Martin ^bd   Bennett, David A ^db,dc   Powell, John ^al   Golde, Todd E ^az,fw   Graff, Caroline ^an,ao   De Jager, Philip L ^fx   Morgan, Kevin ^ap   Ertekin Taner, Nilufer ^as,ed   Combarros, Onofre ^af   Psaty, Bruce M ^j,ax,br   Passmore, Peter ^ar   Younkin, Steven G ^as,ed   Berr, Claudine ^bg,fy,fz   Gudnason, Vilmundur ^g,ab   Rujescu, Dan ^bc   Dickson, Dennis W ^as   Dartigues, Jean François ^ga   Destefano, Anita L ^m,aa   Ortega Cubero, Sara ^ax,gb,gc   Hakonarson, Hakon ^gd   Campion, Dominique ^aj,ak   Boada, Merce ^p   Kauwe, John Keoni ^ge   Farrer, Lindsay A ^l,eh   Van Broeckhoven, Christine ^n,o   Ikram, M Arfan ^b   Jones, Lesley ^a   Haines, Jonathan L ^gf   Tzourio, Christophe ^bf,ey   Escott Price, Valentina ^a   Mayeux, Richard ^t,u   Deleuze, Jean François ⁱ   Amin, Najaf ^b   Goate, Alison M ^dl   Pericak Vance, Margaret A ^h   Amouyel, Philippe ^d,e,f,bi   Van Duijn, Cornelia M ^b   Ramirez, Alfredo ^k,bn   Wang, Li San ^c   Lambert, Jean Charles ^d,e,f   Seshadri, Sudha ^l,m   Williams, Julie ^a   Schellenberg, Gerard D ^c   more..

^a Cardiff University   (United Kingdom)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d Univ Lille   (France)

^e INSTITUT PASTEUR DE LILLE   (France)

^f UNIV LILLE   (France)

^g ICELANDIC HEART ASSOCIATION   (Iceland)

^h UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

ⁱ DIF   (France)

^j UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^k UNIVERSITY OF BONN   (Germany)

^l BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^m FRAMINGHAM HEART STUDY   (United States)

ⁿ DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^o UNIVERSITY OF ANTWERP   (Belgium)

^p Institut Catala de Neurociencies Aplicades   (Spain)

^q GENENTECH INC   (United States)

^r UNIVERSITY HOSPITAL BASEL   (Switzerland)

^s UNIVERSITY OF TEXAS SCHOOL OF PUBLIC HEALTH   (United States)

^t Och Spine at New York Presbyterian Hospitals   (United States)

^u Vagelos College of Physicians and Surgeons   (United States)

^v UNIVERSITY OF EASTERN FINLAND   (Finland)

^w KUOPIO UNIVERSITY HOSPITAL   (Finland)

^x BRIGHAM AND WOMEN S HOSPITAL   (United States)

^y INSERM   (France)

^z GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^aa BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^ab UNIVERSITY OF ICELAND   (Iceland)

^ac INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^ad DUBLIN CITY UNIVERSITY   (Ireland)

^ae UNIVERSITY OF CAGLIARI   (Italy)

^af UNIVERSITY OF CANTABRIA   (Spain)

^ag HOSPITAL UNIVERSITARIO DE GRAN CANARIA DR NEGRÍN   (Spain)

^ah UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^ai UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

^aj CHS du Rouvray   (France)

^ak UNIVERSITY OF ROUEN   (France)

^al KING'S COLLEGE LONDON   (United Kingdom)

^am QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^an KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^ao KAROLINSKA INSTITUTE   (Sweden)

^ap UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^aq UNIVERSITY OF BARI   (Italy)

^ar QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^as MAYO GRADUATE SCHOOL   (United States)

^at CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

^au UNIVERSITY OF PERUGIA   (Italy)

^av ROUEN UNIVERSITY HOSPITAL   (France)

^aw HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^ax CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

^ay NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^az UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^ba UNIVERSITY OF PARMA   (Italy)

^bb Center for Cognitive Disorders AUSL   (Italy)

^bc MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^bd UPPSALA UNIVERSITY   (Sweden)

^be AXA   (France)

^bf SORBONNE UNIVERSITÉ   (France)

^bg PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^bh NATIONAL INSTITUTE ON AGING   (United States)

^bi LILLE UNIVERSITY HOSPITAL   (France)

^bj CHU Lille   (France)

^bk UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

^bl UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^bm UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^bn UNIVERSITY OF COLOGNE   (Germany)

^bo JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^bp UNIVERSITY OF LEIPZIG   (Germany)

^bq UNIVERSITY OF ICELAND   (Iceland)

^br UNIVERSITY OF WASHINGTON   (United States)

^bs MEDICAL UNIVERSITY OF GRAZ   (Austria)

^bt HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^bu MASSACHUSETTS GENERAL HOSPITAL   (United States)

^bv CATHOLIC UNIVERSITY   (Italy)

^bw BAYLOR COLLEGE OF MEDICINE   (United States)

^bx IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^by UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^bz INDIANA UNIVERSITY   (United States)

^ca UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^cb UNIVERSITY OF PITTSBURGH   (United States)

^cc WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^cd ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^ce UTAH STATE UNIVERSITY   (United States)

^cf BST   (Spain)

^cg HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^ch UNIVERSITÉ DE TOULOUSE   (France)

^ci MEDICAL UNIVERSITY OF LODZ   (Poland)

^cj UNIVERSITY OF LEICESTER   (United Kingdom)

^ck UNIVERSITY COLLEGE LONDON   (United Kingdom)

^cl UNIVERSITY OF MILAN   (Italy)

^cm SAARLAND UNIVERSITY   (Germany)

^cn UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^co ASP Catanzaro   (Italy)

^cp UNIVERSITY OF FLORENCE   (Italy)

^cq IRCCS 'Don Carlo Gnocchi'   (Italy)

^cr UNIVERSITY HOSPITAL ESSEN   (Germany)

^cs UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^ct OASI RESEARCH INSTITUTE IRCCS   (Italy)

^cu ST JAMES S HOSPITAL   (Ireland)

^cv UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^cw VA ANN ARBOR HEALTHCARE SYSTEM   (United States)

^cx UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^cy INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^cz UNIVERSITY OF WISCONSIN MADISON   (United States)

^da UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^db RUSH UNIVERSITY MEDICAL CENTER   (United States)

^dc RUSH UNIVERSITY MEDICAL CENTER   (United States)

^dd SUN HEALTH RESEARCH INSTITUTE   (United States)

^de NORTHWESTERN UNIVERSITY   (United States)

^df VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

^dg MAYO CLINIC   (United States)

^dh SWEDISH MEDICAL CENTER   (United States)

^di UNIVERSITY OF CALIFORNIA   (United States)

^dj DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^dk UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^dl MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^dm UNIVERSITY OF SOUTH FLORIDA   (United States)

^dn Fred Hutchinson Cancer Research Center   (United States)

^do MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^dp UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^dq RALPH H JOHNSON VA MEDICAL CENTER   (United States)

^dr UNIVERSITY OF CALIFORNIA   (United States)

^ds UNIVERSITY OF CALIFORNIA   (United States)

^dt UNIVERSITY OF CALIFORNIA   (United States)

^du MOUNT SINAI MEDICAL CENTER   (United States)

^dv RUSH UNIVERSITY MEDICAL CENTER   (United States)

^dw University of Alabama at Birmingham   (United States)

^dx UNIVERSITY OF KENTUCKY   (United States)

^dy NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^dz UNIVERSITY OF CALIFORNIA   (United States)

^ea EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^eb EMORY UNIVERSITY   (United States)

^ec UNIVERSITY OF CALIFORNIA   (United States)

^ed MAYO CLINIC   (United States)

^ee University of Alabama at Birmingham   (United States)

^ef TRANSLATIONAL GENOMICS RESEARCH INSTITUTE   (United States)

^eg UNIVERSITY OF KENTUCKY COLLEGE OF PUBLIC HEALTH   (United States)

^eh BOSTON UNIVERSITY   (United States)

^ei OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^ej PORTLAND VA MEDICAL CENTER   (United States)

^ek UNIVERSITY OF CALIFORNIA   (United States)

^el LERNER RESEARCH INSTITUTE   (United States)

^em NEW YORK UNIVERSITY   (United States)

^en UNIVERSITY OF CALIFORNIA   (United States)

^eo University of North Texas Health Science Center   (United States)

^ep UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

^eq UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^er UNIVERSITY OF CALIFORNIA   (United States)

^es UNIVERSITY OF TORONTO   (Canada)

^et NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^eu UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^ev Hospital Network Antwerp   (Belgium)

^ew UNIVERSITY OF LEUVEN   (Belgium)

^ex Paris Descartes University   (France)

^ey UNIVERSITÉ DE BORDEAUX   (France)

^ez Montpellier 1 University   (France)

^fa INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE   (France)

^fb GROUP HEALTH RESEARCH INSTITUTE   (United States)

^fc LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE   (United States)

^fd CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

^fe Asturias University Hospital   (Spain)

^ff Netherlands Consortium for Health Ageing   (Netherlands)

^fg ARIZONA ALZHEIMER S CONSORTIUM   (United States)

^fh BANNER ALZHEIMER S INSTITUTE   (United States)

^fi UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^fj UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^fk LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^fl UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^fm UNIVERSITY OF PISA   (Italy)

^fn PFIZER INC   (United States)

^fo TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

^fp CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^fq UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^fr UNIVERSITY OF AVEIRO   (Portugal)

^fs UNIVERSITY OF MANCHESTER   (United Kingdom)

^ft ARISTOTLE UNIVERSITY MEDICAL SCHOOL   (Greece)

^fu UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^fv UNIVERSITY OF OXFORD   (United Kingdom)

^fw UNIVERSITY OF FLORIDA HEALTH   (United States)

^fx NewYork Presbyterian Hospital   (United States)

^fy GUI DE CHAULIAC HOSPITAL   (France)

^fz UNIV MONTPELLIER   (France)

^ga CMRR de Bordeaux   (France)

^gb UNIVERSITY OF NAVARRA   (Spain)

^gc Gerencia Regional de Salud de Castilla y León   (Spain)

^gd CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^ge BRIGHAM YOUNG UNIVERSITY   (United States)

^gf CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHOLIPASE C GAMMA2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ABI3; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2; UNCLASSIFIED DRUG; ABI3 PROTEIN, HUMAN; IMMUNOGLOBULIN RECEPTOR; MEMBRANE PROTEIN; PHOSPHOLIPASE C GAMMA; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TREM2 PROTEIN, HUMAN;

ALZHEIMER DISEASE; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; GENE EXPRESSION; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HUMAN; INNATE IMMUNITY; MAJOR CLINICAL STUDY; MICROARRAY ANALYSIS; MICROGLIA; NEUROPATHOLOGY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SINGLE NUCLEOTIDE POLYMORPHISM; WHOLE EXOME SEQUENCING; AMINO ACID SEQUENCE; EXOME; GENE EXPRESSION PROFILING; GENE LINKAGE DISEQUILIBRIUM; GENETIC PREDISPOSITION; GENETICS; METABOLISM; ODDS RATIO; SEQUENCE HOMOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ALZHEIMER DISEASE; AMINO ACID SEQUENCE; CASE-CONTROL STUDIES; EXOME; GENE EXPRESSION PROFILING; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; IMMUNITY, INNATE; LINKAGE DISEQUILIBRIUM; MEMBRANE GLYCOPROTEINS; MICROGLIA; ODDS RATIO; PHOSPHOLIPASE C GAMMA; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN INTERACTION MAPS; RECEPTORS, IMMUNOLOGIC; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 85028725970     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3916     Document Type: Article

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