A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death

Nature Medicine

Volumn 20, Issue 12, 2014, Pages 1452-1457

  Wetzel Smith, Monica K ^a   Hunkapiller, Julie ^a   Bhangale, Tushar R ^a   Srinivasan, Karpagam ^a   Maloney, Janice A ^a   Atwal, Jasvinder K ^a   Sa, Susan M ^a   Yaylaoglu, Murat B ^a   Foreman, Oded ^a   Ortmann, Ward ^a   Rathore, Nisha ^a   Hansen, David V ^a   Tessier Lavigne, Marc ^b   Mayeux, Richard ^c,d   Pericak Vance, Margaret ^e   Haines, Jonathan ^f   Farrer, Lindsay A ^g,h   Schellenberg, Gerard D ^g,i   Goate, Alison ^j   Behrens, Timothy W ^a   Cruchaga, Carlos ^j   Watts, Ryan J ^a   Graham, Robert R ^a   more..

^a GENENTECH INC   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Gertrude H Sergievsky Center   (United States)

^e UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^f CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g BOSTON UNIVERSITY   (United States)

^h BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁱ UNIVERSITY OF PENNSYLVANIA   (United States)

^j WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; CELL SURFACE RECEPTOR; GLUTAMIC ACID; NERVE GROWTH FACTOR RECEPTOR; NETRIN RECEPTORS; STAUROSPORINE; UNC5C PROTEIN, HUMAN; UNC5C PROTEIN, MOUSE; UNC5C PROTEIN, RAT;

AGED; ALZHEIMER DISEASE; ANIMAL; CELL DEATH; CYTOLOGY; FEMALE; GENETIC PREDISPOSITION; GENETICS; HEK293 CELL LINE; HIPPOCAMPAL CA3 REGION; HUMAN; MALE; METABOLISM; MOUSE; NERVE CELL; RAT; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; CA3 REGION, HIPPOCAMPAL; CELL DEATH; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GLUTAMIC ACID; HEK293 CELLS; HUMANS; MALE; MICE; NEURONS; RATS; RECEPTORS, CELL SURFACE; RECEPTORS, NERVE GROWTH FACTOR; STAUROSPORINE;

EID: 84937526426     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3736     Document Type: Article

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