Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Escott Price, Valentina ^a   Bellenguez, Céline ^b,c,d   Wang, Li San ^e   Choi, Seung Hoan ^f   Harold, Denise ^a   Jones, Lesley ^a   Holmans, Peter ^a   Gerrish, Amy ^a   Vedernikov, Alexey ^a   Richards, Alexander ^a   DeStefano, Anita L ^f   Lambert, Jean Charles ^b,c,d   Ibrahim Verbaas, Carla A ^g   Naj, Adam C ^e   Sims, Rebecca ^a   Jun, Gyungah ^f,h   Bis, Joshua C ⁱ   Beecham, Gary W ^j   Grenier Boley, Benjamin ^b,c,d   Russo, Giancarlo ^k   Thornton Wells, Tricia A ^l   Denning, Nicola ^a   Smith, Albert V ^m,n   Chouraki, Vincent ^b,c,d,h   Thomas, Charlene ^a   Arfan Ikram, M ^g,o   Zelenika, Diana ^p   Vardarajan, Badri N ^h,v,w   Kamatani, Yoichiro ^q   Lin, Chiao Feng ^e   Schmidt, Helena ^r   Kunkle, Brian ^j   Dunstan, Melanie L ^a   Vronskaya, Maria ^a   Johnson, Andrew D ^t   Ruiz, Agustin ^u   Bihoreau, Marie Thérèse ^p   Reitz, Christiane ^v,w   Pasquier, Florence ^c,s   Hollingworth, Paul ^a   Hanon, Olivier ^x   Fitzpatrick, Annette L ^i,y   Buxbaum, Joseph D ^z   Campion, Dominique ^aa   Crane, Paul K ^y   Becker, Clinton Baldwin Tim ^h,ab,bm   Gudnason, Vilmundur ^m,n   Cruchaga, Carlos ^ac   Craig, David ^ad   Amin, Najaf ^g   Berr, Claudine ^ae   Lopez, Oscar L ^af   De Jager, Philip L ^ag,ah   Deramecourt, Vincent ^c,s   Johnston, Janet A ^ad   Evans, Denis ^ai   Lovestone, Simon ^aj   Letenneur, Luc ^b   Hernández, Isabel ^u   Rubinsztein, David C ^ak   Eiriksdottir, Gudny ⁿ   Sleegers, Kristel ^al,am   Goate, Alison M ^ac   Fiévet, Nathalie ^b,d   Huentelman, Matthew J ^an   Gill, Michael ^ao   Brown, Kristelle ^ap   Kamboh, M Ilyas ^af,aq   Keller, Lina ^ar   Barberger Gateau, Pascale ^aj   McGuinness, Bernadette ^ad   Larson, Eric B ^y,as   Myers, Amanda J ^j   Dufouil, Carole ^b   Todd, Stephen ^ad   Wallon, David ^aa   Love, Seth ^at   Rogaeva, Ekaterina ^au   Gallacher, John ^a   St George Hyslop, Peter ^ak,au   Clarimon, Jordi ^av,aw   Lleo, Alberto ^av,aw   Bayer, Anthony ^a   Tsuang, Debby W ⁱ   Yu, Lei ^ax   Tsolaki, Magda ^ay   Bossù, Paola ^az   Spalletta, Gianfranco ^az   Proitsi, Petra ^aj   Collinge, John ^ba   Sorbi, Sandro ^bb   Sanchez Garcia, Florentino ^bc   Fox, Nick C ^ba   Hardy, John ^bd   Naranjo, Maria Candida Deniz ^bc   Bosco, Paolo ^be   Clarke, Robert ^bf   Brayne, Carol ^bg   Galimberti, Daniela ^bh   Scarpini, Elio ^bh   Bonuccelli, Ubaldo ^bi   Mancuso, Michelangelo ^bi   Siciliano, Gabriele ^bi   Moebus, Susanne ^bj   Mecocci, Patrizia ^bk   Del Zompo, Maria ^bl   Maier, Wolfgang ^ab,bm   Hampel, Harald ^bn,bo   Pilotto, Alberto ^bp   Frank García, Ana ^aw,bq,br   Panza, Francesco ^bs   Solfrizzi, Vincenzo ^bs   Caffarra, Paolo ^bt,bu   Nacmias, Benedetta ^bb   Perry, William ^j   Mayhaus, Manuel ^bv   Lannfelt, Lars ^bw   Hakonarson, Hakon ^bx   Pichler, Sabrina ^bv   Carrasquillo, Minerva M ^by   Ingelsson, Martin ^bw   Beekly, Duane ^y   Alvarez, Victoria ^bz   Zou, Fanggeng ^by   Valladares, Otto ^e   Younkin, Steven G ^by   Coto, Eliecer ^bz   Hamilton Nelson, Kara L ^j   Gu, Wei ^bv   Razquin, Cristina ^ca   Pastor, Pau ^ca,cb   Mateo, Ignacio ^cc   Owen, Michael J ^a   Faber, Kelley M ^cd   Jonsson, Palmi V ^m,ce   Combarros, Onofre ^cc   O'Donovan, Michael C ^a   Cantwell, Laura B ^e   Soininen, Hilkka ^cf,cg   Blacker, Deborah ^ag,ch   Mead, Simon ^ba   Mosley Jr , Thomas H ^ci   Bennett, David A ^ax,cj   Harris, Tamara B ^ck   Fratiglioni, Laura ^ar,cl   Holmes, Clive ^cm   De Bruijn, Renee F A G ^g   Passmore, Peter ^ad   Montine, Thomas J ^y   Bettens, Karolien ^al,am   Rotter, Jerome I ^cn   Brice, Alexis ^co,cp   Morgan, Kevin ^ap   Foroud, Tatiana M ^cd   Kukull, Walter A ^y   Hannequin, Didier ^aa   Powell, John F ^aj   Nalls, Michael A ^cq   Ritchie, Karen ^ae,cr   Lunetta, Kathryn L ^f   Kauwe, John S K ^cs   Boerwinkle, Eric ^cs,ct,cu   Riemenschneider, Matthias ^ab   Boada, Mercè ^u,cv   Hiltunen, Mikko ^cf,cg   Martin, Eden R ^j   Schmidt, Reinhold ^r   Rujescu, Dan ^bo   Dartigues, Jean François ^b,cw   Mayeux, Richard ^v,w   Tzourio, Christophe ^b   Hofman, Albert ^g,o   Nöthen, Markus M ^bm   Graff, Caroline ^cl,cx   Psaty, Bruce M ^i,cy   Haines, Jonathan L ^cz,da   Lathrop, Mark ^h,q,db   Pericak Vance, Margaret A ^j   Launer, Lenore J ^ck   Van Broeckhoven, Christine ^al,am   Farrer, Lindsay A ^f,h   Van Duijn, Cornelia M ^g,o,dc   Ramirez, Alfredo ^bm   Seshadri, Sudha ^h,t   Schellenberg, Gerard D ^e   Amouyel, Philippe ^b,c,d,s   Williams, Julie ^a   more..

^a CARDIFF UNIVERSITY   (United Kingdom)

^b INSERM   (France)

^c UNIV LILLE   (France)

^d INSTITUT PASTEUR DE LILLE   (France)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

^f BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^g ERASMUS MEDICAL CENTER   (Netherlands)

^h BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁱ UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^j UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^k UNIVERSITY OF ZURICH   (Switzerland)

^l VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^m UNIVERSITY OF ICELAND   (Iceland)

ⁿ ICELANDIC HEART ASSOCIATION   (Iceland)

^o Netherlands Consortium for Healthy Ageing   (Netherlands)

^p CENTRE NATIONAL DE GÉNOTYPAGE   (France)

^q FONDATION JEAN DAUSSET CEPH   (France)

^r MEDICAL UNIVERSITY OF GRAZ   (Austria)

^s LILLE UNIVERSITY HOSPITAL   (France)

^t FRAMINGHAM HEART STUDY   (United States)

^u Institut Catala de Neurociencies Aplicades   (Spain)

^v Och Spine at New York Presbyterian Hospitals   (United States)

^w Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Gertrude H Sergievsky Center   (United States)

^x UNIVERSITÉ PARIS DESCARTES   (France)

^y UNIVERSITY OF WASHINGTON   (United States)

^z MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^aa ROUEN UNIVERSITY HOSPITAL   (France)

^ab GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^ac WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^ad QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^ae Montpellier 1 University   (France)

^af UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^ag MASSACHUSETTS GENERAL HOSPITAL   (United States)

^ah BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^ai RUSH UNIVERSITY MEDICAL CENTER   (United States)

^aj KING'S COLLEGE LONDON   (United Kingdom)

^ak UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^al DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^am UNIVERSITY OF ANTWERP   (Belgium)

^an TRANSLATIONAL GENOMICS RESEARCH INSTITUTE   (United States)

^ao TRINITY COLLEGE DUBLIN   (Ireland)

^ap UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^aq UNIVERSITY OF PITTSBURGH   (United States)

^ar STOCKHOLM UNIVERSITY   (Sweden)

^as GROUP HEALTH RESEARCH INSTITUTE   (United States)

^at UNIVERSITY OF BRISTOL   (United Kingdom)

^au UNIVERSITY OF TORONTO   (Canada)

^av UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^aw CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

^ax RUSH UNIVERSITY MEDICAL CENTER   (United States)

^ay ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^az IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^ba UNIVERSITY COLLEGE LONDON   (United Kingdom)

^bb UNIVERSITY OF FLORENCE   (Italy)

^bc HOSPITAL UNIVERSITARIO DE GRAN CANARIA DR NEGRÍN   (Spain)

^bd UNIVERSITY COLLEGE LONDON   (United Kingdom)

^be OASI RESEARCH INSTITUTE IRCCS   (Italy)

^bf UNIVERSITY OF OXFORD   (United Kingdom)

^bg UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^bh UNIVERSITY OF MILAN   (Italy)

^bi UNIVERSITY OF PISA   (Italy)

^bj UNIVERSITY HOSPITAL ESSEN   (Germany)

^bk UNIVERSITY OF PERUGIA   (Italy)

^bl UNIVERSITY OF CAGLIARI   (Italy)

^bm UNIVERSITY OF BONN   (Germany)

^bn GOETHE UNIVERSITY   (Germany)

^bo UNIVERSITY OF MUNICH   (Germany)

^bp CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

^bq CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

^br HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^bs UNIVERSITY OF BARI   (Italy)

^bt UNIVERSITY OF PARMA   (Italy)

^bu Center for Cognitive Disorders AUSL   (Italy)

^bv University Hospital   (Germany)

^bw UPPSALA UNIVERSITY   (Sweden)

^bx CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^by MAYO GRADUATE SCHOOL   (United States)

^bz Genetica Molecular Huca Oviedo   (Spain)

^ca UNIVERSITY OF NAVARRA   (Spain)

^cb INSTITUTO DE SALUD CARLOS III   (Spain)

^cc UNIVERSITY OF CANTABRIA   (Spain)

^cd INDIANA UNIVERSITY   (United States)

^ce LANDSPITALI UNIVERSITY HOSPITAL   (Iceland)

^cf UNIVERSITY OF EASTERN FINLAND   (Finland)

^cg KUOPIO UNIVERSITY HOSPITAL   (Finland)

^ch HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^ci UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^cj RUSH UNIVERSITY MEDICAL CENTER   (United States)

^ck NATIONAL INSTITUTES OF HEALTH   (United States)

^cl KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^cm UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^cn LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE   (United States)

^co SORBONNE UNIVERSITÉ   (France)

^cp PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^cq NATIONAL INSTITUTE ON AGING   (United States)

^cr IMPERIAL COLLEGE LONDON   (United Kingdom)

^cs BRIGHAM YOUNG UNIVERSITY   (United States)

^ct BAYLOR COLLEGE OF MEDICINE   (United States)

^cu UNIVERSITY OF TEXAS   (United States)

^cv HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^cw BORDEAUX UNIVERSITY HOSPITAL   (France)

^cx KAROLINSKA INSTITUTE   (Sweden)

^cy CENTER FOR HEALTH STUDIES   (United States)

^cz VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^da CASE WESTERN RESERVE UNIVERSITY   (United States)

^db MCGILL UNIVERSITY   (Canada)

^dc Center for Medical Systems Biology   (Netherlands)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; ARTICLE; CHROMOSOME 8; CONTROLLED STUDY; ENERGY METABOLISM; GENE; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCUS; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; IGHV1 67 GENE; IMMUNE SYSTEM; MTCH2 GENE; NDUFS3 GENE; PATHOGENESIS; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; TP53INP1 GENE; ZNF3 GENE; CASE CONTROL STUDY; GENETICS; GENOME-WIDE ASSOCIATION STUDY; SINGLE NUCLEOTIDE POLYMORPHISM;

CARRIER PROTEIN; HEAT SHOCK PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; TP53INP1 PROTEIN, HUMAN;

ALZHEIMER DISEASE; CARRIER PROTEINS; CASE-CONTROL STUDIES; GENOME-WIDE ASSOCIATION STUDY; HEAT-SHOCK PROTEINS; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, ANTIGEN, B-CELL;

EID: 84903520463     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0094661     Document Type: Article

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