A rare functional cardioprotective APOC3 variant has risen in frequency in distinct population isolates

Nature Communications

Volumn 4, Issue , 2013, Pages

  Tachmazidou, Ioanna ^a   Dedoussis, George ^b   Southam, Lorraine ^a,c   Farmaki, Aliki Eleni ^b   Ritchie, Graham R S ^a,d   Xifara, Dionysia K ^c,e   Matchan, Angela ^a   Hatzikotoulas, Konstantinos ^a   Rayner, Nigel W ^a,c   Chen, Yuan ^a   Pollin, Toni I ^f   O'Connell, Jeffrey R ^f   Yerges Armstrong, Laura M ^f   Kiagiadaki, Chrysoula ^g   Panoutsopoulou, Kalliope ^a   Schwartzentruber, Jeremy ^a   Moutsianas, Loukas ^c   Tsafantakis, Emmanouil ^g   Tyler Smith, Chris ^a   McVean, Gil ^c   Xue, Yali ^a   Zeggini, Eleftheria ^a   more..

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b HAROKOPIO UNIVERSITY   (Greece)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Italy)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^g Anogia Health Center   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

CARDIOVASCULAR SYSTEM; GENOME; HOMINID; ISOLATED POPULATION; LIPID;

ADULT; AGED; AMISH; ARTICLE; CONTROLLED STUDY; EXOME; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC CODE; GENETIC VARIABILITY; GENOTYPE; GREECE; HAPLOTYPE; HEART PROTECTION; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; POPULATION RESEARCH;

ADULT; AGED; AGED, 80 AND OVER; APOLIPOPROTEIN C-III; CARDIOVASCULAR DISEASES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE FREQUENCY; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; GREECE; HAPLOTYPES; HUMANS; LIPOPROTEINS, HDL; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; TRIGLYCERIDES;

EID: 84890690821     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms3872     Document Type: Article

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