-
1
-
-
79952730699
-
2011 Alzheimer's disease facts and figures
-
Thies W, Bleiler L. 2011 Alzheimer's disease facts and figures. Alzheimers Dement 2011;7:208-244.
-
(2011)
Alzheimers Dement
, vol.7
, pp. 208-244
-
-
Thies, W.1
Bleiler, L.2
-
2
-
-
0002687033
-
Genetics and the dementia patient
-
Farrer LA. Genetics and the dementia patient. Neurologist 1997;3:13-30.
-
(1997)
Neurologist
, vol.3
, pp. 13-30
-
-
Farrer, L.A.1
-
3
-
-
0030823158
-
Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis
-
APOE and Alzheimer Disease Meta Analysis Consortium
-
Farrer LA, Cupples LA, Haines JL, et al. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. JAMA 1997;278:1349-1356.
-
(1997)
JAMA
, vol.278
, pp. 1349-1356
-
-
Farrer, L.A.1
Cupples, L.A.2
Haines, J.L.3
-
4
-
-
84888317489
-
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
-
Lambert JC, Ibrahim-Verbaas CA, Harold D, et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet 2013;45:1452-1458.
-
(2013)
Nat Genet
, vol.45
, pp. 1452-1458
-
-
Lambert, J.C.1
Ibrahim-Verbaas, C.A.2
Harold, D.3
-
5
-
-
84856200093
-
Towards unveiling the genetics of neurodegenerative diseases
-
Lill CM, Bertram L. Towards unveiling the genetics of neurodegenerative diseases. Semin Neurol 2012;31:531-541.
-
(2012)
Semin Neurol
, vol.31
, pp. 531-541
-
-
Lill, C.M.1
Bertram, L.2
-
6
-
-
84856145841
-
Genetics of dementia
-
Paulson HL, Igo I. Genetics of dementia. Semin Neurol 2012;31:449-460.
-
(2012)
Semin Neurol
, vol.31
, pp. 449-460
-
-
Paulson, H.L.1
Igo, I.2
-
7
-
-
79955464911
-
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with lateonset Alzheimer's disease
-
Naj AC, Jun G, Beecham GW, et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with lateonset Alzheimer's disease. Nat Genet 2011;43:436-441.
-
(2011)
Nat Genet
, vol.43
, pp. 436-441
-
-
Naj, A.C.1
Jun, G.2
Beecham, G.W.3
-
8
-
-
79955841697
-
Evaluating the heritability explained by known susceptibility variants: A survey of ten complex diseases
-
So HC, Gui AH, Cherny SS, Sham PC. Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases. Genet Epidemiol 2011;35:310-317.
-
(2011)
Genet Epidemiol
, vol.35
, pp. 310-317
-
-
So, H.C.1
Gui, A.H.2
Cherny, S.S.3
Sham, P.C.4
-
9
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio TA, Collins FS, Cox NJ, et al. Finding the missing heritability of complex diseases. Nature 2009;461:747-753.
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
Collins, F.S.2
Cox, N.J.3
-
10
-
-
79955906475
-
Power and pitfalls of the genome-wide association study approach to identify genes for Alzheimer's disease
-
Sherva R, Farrer LA. Power and pitfalls of the genome-wide association study approach to identify genes for Alzheimer's disease. Curr Psychiatry Rep 2011;13:138-146.
-
(2011)
Curr Psychiatry Rep
, vol.13
, pp. 138-146
-
-
Sherva, R.1
Farrer, L.A.2
-
11
-
-
82455170451
-
Using linkage analysis of large pedigrees to guide association analyses
-
Choi SH, Liu C, Dupuis J, et al. Using linkage analysis of large pedigrees to guide association analyses. BMC Proc 2011;5(suppl 9):S79.
-
(2011)
BMC Proc
, vol.5
, pp. S79
-
-
Choi, S.H.1
Liu, C.2
Dupuis, J.3
-
12
-
-
0028864636
-
The effect of education on the incidence of dementia and Alzheimer's disease in the Framingham Study
-
Cobb JL, Wolf PA, Au R, et al. The effect of education on the incidence of dementia and Alzheimer's disease in the Framingham Study. Neurology 1995;45:1707-1712.
-
(1995)
Neurology
, vol.45
, pp. 1707-1712
-
-
Cobb, J.L.1
Wolf, P.A.2
Au, R.3
-
13
-
-
79952256613
-
Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE
-
Wijsman EM, Pankratz ND, Choi Y, et al. Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE. PLoS Genet 2011;7:e1001308.
-
(2011)
PLoS Genet
, vol.7
, pp. e1001308
-
-
Wijsman, E.M.1
Pankratz, N.D.2
Choi, Y.3
-
14
-
-
84898739139
-
SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians
-
Miyashita A, Koike A, Jun G, et al. SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians. PLoS One 2013;8:e58618.
-
(2013)
PLoS One
, vol.8
, pp. e58618
-
-
Miyashita, A.1
Koike, A.2
Jun, G.3
-
15
-
-
84875922261
-
Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E 4,and the risk of late-onset Alzheimer disease in African Americans
-
Reitz C, Jun G, Naj A, et al. Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E 4,and the risk of late-onset Alzheimer disease in African Americans. JAMA 2013;309:1483-1492.
-
(2013)
JAMA
, vol.309
, pp. 1483-1492
-
-
Reitz, C.1
Jun, G.2
Naj, A.3
-
16
-
-
77952307991
-
Genome-wide analysis of genetic loci associated with Alzheimer disease
-
Seshadri S, Fitzpatrick AL, Ikram MA, et al. Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA 2010;303:1832-1840.
-
(2010)
JAMA
, vol.303
, pp. 1832-1840
-
-
Seshadri, S.1
Fitzpatrick, A.L.2
Ikram, M.A.3
-
17
-
-
77957909886
-
Meta-analysis confirms CR1, CLU, and PICALM as Alzheimer disease risk loci and reveals interactions with APOE genotypes
-
Jun G, Naj AC, Beecham GW, et al. Meta-analysis confirms CR1, CLU, and PICALM as Alzheimer disease risk loci and reveals interactions with APOE genotypes. Arch Neurol 2010;67:1473-1484.
-
(2010)
Arch Neurol
, vol.67
, pp. 1473-1484
-
-
Jun, G.1
Naj, A.C.2
Beecham, G.W.3
-
18
-
-
37549064336
-
Mach 1.0: Rapid haplotype reconstruction and missing genotype inference
-
Li Y, Abecasis GR. Mach 1.0: rapid haplotype reconstruction and missing genotype inference. Am J Hum Genet 2006;S79:2290.
-
(2006)
Am J Hum Genet
, vol.S79
, pp. 2290
-
-
Li, Y.1
Abecasis, G.R.2
-
19
-
-
84866274928
-
Delta-catenin is genetically and biologically associated with cortical cataract and future Alzheimer-related structural and functional brain changes
-
Jun G, Moncaster JA, Koutras C, et al. Delta-catenin is genetically and biologically associated with cortical cataract and future Alzheimer-related structural and functional brain changes. PLoS One 2012;7:e43728.
-
(2012)
PLoS One
, vol.7
, pp. e43728
-
-
Jun, G.1
Moncaster, J.A.2
Koutras, C.3
-
20
-
-
0031923684
-
Analytic strategies to detect linkage to a common disorder with genetically determined age of onset: Diabetes mellitus in Pima Indians
-
Hanson RL, Knowler WC. Analytic strategies to detect linkage to a common disorder with genetically determined age of onset: diabetes mellitus in Pima Indians. Genet Epidemiol 1998;15:299-315.
-
(1998)
Genet Epidemiol
, vol.15
, pp. 299-315
-
-
Hanson, R.L.1
Knowler, W.C.2
-
21
-
-
78751547278
-
Propensity score-based nonparametric test revealing genetic variants underlying bipolar disorder
-
Jiang Y, Zhang H. Propensity score-based nonparametric test revealing genetic variants underlying bipolar disorder. Genet Epidemiol 2011;35:125-132.
-
(2011)
Genet Epidemiol
, vol.35
, pp. 125-132
-
-
Jiang, Y.1
Zhang, H.2
-
22
-
-
84055184759
-
Some capabilities for model-based and model-free linkage analysis using the program package S.A.G.E. (Statistical Analysis for Genetic Epidemiology)
-
Schnell AH, Sun X, Igo RP Jr, Elston RC. Some capabilities for model-based and model-free linkage analysis using the program package S.A.G.E. (Statistical Analysis for Genetic Epidemiology). Hum Hered 2011;72:237-246.
-
(2011)
Hum Hered
, vol.72
, pp. 237-246
-
-
Schnell, A.H.1
Sun, X.2
Igo, R.P.3
Elston, R.C.4
-
23
-
-
68249120153
-
EPHA2 is associated with age-related cortical cataract in mice and humans
-
Jun G, Guo H, Klein BE, et al. EPHA2 is associated with age-related cortical cataract in mice and humans. PLoS Genet 2009;5:e1000584.
-
(2009)
PLoS Genet
, vol.5
, pp. e1000584
-
-
Jun, G.1
Guo, H.2
Klein, B.E.3
-
24
-
-
70350454030
-
Calculating asymptotic significance levels of the constrained likelihood ratio test with application to multivariate genetic linkage analysis
-
Morris NJ, Elston R, Stein CM. Calculating asymptotic significance levels of the constrained likelihood ratio test with application to multivariate genetic linkage analysis. Stat Appl Genet Mol Biol 2009;8:Article 39.
-
(2009)
Stat Appl Genet Mol Biol
, vol.8
-
-
Morris, N.J.1
Elston, R.2
Stein, C.M.3
-
25
-
-
21344445009
-
Two-level Haseman-Elston regression for general pedigree data analysis
-
Wang T, Elston RC. Two-level Haseman-Elston regression for general pedigree data analysis. Genet Epidemiol 2005;29:12-22.
-
(2005)
Genet Epidemiol
, vol.29
, pp. 12-22
-
-
Wang, T.1
Elston, R.C.2
-
26
-
-
77955064853
-
A versatile gene-based test for genome-wide association studies
-
Liu JZ, McRae AF, Nyholt DR, et al. A versatile gene-based test for genome-wide association studies. AmJ Hum Genet 2010;87:139-145.
-
(2010)
AmJ Hum Genet
, vol.87
, pp. 139-145
-
-
Liu, J.Z.1
McRae, A.F.2
Nyholt, D.R.3
-
27
-
-
77955894071
-
METAL: Fast and efficient meta-analysis of genomewide association scans
-
Willer CJ, Li Y, Abecasis GR. METAL: fast and efficient meta-analysis of genomewide association scans. Bioinformatics 2010;26:2190-2191.
-
(2010)
Bioinformatics
, vol.26
, pp. 2190-2191
-
-
Willer, C.J.1
Li, Y.2
Abecasis, G.R.3
-
28
-
-
84980053106
-
Lowering of amyloid beta peptide production with a small molecule inhibitor of amyloid-beta precursor protein dimerization
-
So PP, Zeldich E, Seyb KI, et al. Lowering of amyloid beta peptide production with a small molecule inhibitor of amyloid-beta precursor protein dimerization. Am J Neurodegener Dis 2012;1:75-87.
-
(2012)
Am J Neurodegener Dis
, vol.1
, pp. 75-87
-
-
So, P.P.1
Zeldich, E.2
Seyb, K.I.3
-
29
-
-
58149379158
-
Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1
-
Sato S, Xu J, Okuyama S, et al. Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1. J Neurosci 2008;28:14511-14521.
-
(2008)
J Neurosci
, vol.28
, pp. 14511-14521
-
-
Sato, S.1
Xu, J.2
Okuyama, S.3
-
30
-
-
0031781988
-
Regional distribution of neuritic plaques in the nondemented elderly and subjects with very mild Alzheimer disease
-
Haroutunian V, Perl DP, Purohit DP, et al. Regional distribution of neuritic plaques in the nondemented elderly and subjects with very mild Alzheimer disease. Arch Neurol 1998;55:1185-1191.
-
(1998)
Arch Neurol
, vol.55
, pp. 1185-1191
-
-
Haroutunian, V.1
Perl, D.P.2
Purohit, D.P.3
-
31
-
-
20244364929
-
Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates
-
Tamagnone L, Artigiani S, Chen H, et al. Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates. Cell 1999;99:71-80.
-
(1999)
Cell
, vol.99
, pp. 71-80
-
-
Tamagnone, L.1
Artigiani, S.2
Chen, H.3
-
32
-
-
20144389584
-
Plexin-a4 mediates axon-repulsive activities of both secreted and transmembrane semaphorins and plays roles in nerve fiber guidance
-
Suto F, Ito K, Uemura M, et al. Plexin-a4 mediates axon-repulsive activities of both secreted and transmembrane semaphorins and plays roles in nerve fiber guidance. J Neurosci 2005;25:3628-3637.
-
(2005)
J Neurosci
, vol.25
, pp. 3628-3637
-
-
Suto, F.1
Ito, K.2
Uemura, M.3
-
33
-
-
7244221869
-
A role for semaphorin 3A signaling in the degeneration of hippocampal neurons during Alzheimer's disease
-
Good PF, Alapat D, Hsu A, et al. A role for semaphorin 3A signaling in the degeneration of hippocampal neurons during Alzheimer's disease. J Neurochem 2004;91:716-736.
-
(2004)
J Neurochem
, vol.91
, pp. 716-736
-
-
Good, P.F.1
Alapat, D.2
Hsu, A.3
-
34
-
-
9644276856
-
GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins regulates axon elongation in primary neurons
-
Cole AR, Knebel A, Morrice NA, et al. GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins regulates axon elongation in primary neurons. J Biol Chem 2004;279:50176-50180.
-
(2004)
J Biol Chem
, vol.279
, pp. 50176-50180
-
-
Cole, A.R.1
Knebel, A.2
Morrice, N.A.3
-
35
-
-
0033608823
-
Distribution of semaphorin IV in adult human brain
-
Hirsch E, Hu LJ, Prigent A, et al. Distribution of semaphorin IV in adult human brain. Brain Res 1999;823:67-79.
-
(1999)
Brain Res
, vol.823
, pp. 67-79
-
-
Hirsch, E.1
Hu, L.J.2
Prigent, A.3
-
36
-
-
45849100884
-
Plexin signaling selectively regulates the stereotyped pruning of corticospinal axons from visual cortex
-
Low LK, Liu XB, Faulkner RL, et al. Plexin signaling selectively regulates the stereotyped pruning of corticospinal axons from visual cortex. Proc Natl Acad Sci U S A 2008;105:8136-8141.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 8136-8141
-
-
Low, L.K.1
Liu, X.B.2
Faulkner, R.L.3
-
37
-
-
18644374595
-
Fyn and Cdk5 mediate semaphorin-3A signaling, which is involved in regulation of dendrite orientation in cerebral cortex
-
Sasaki Y, Cheng C, Uchida Y, et al. Fyn and Cdk5 mediate semaphorin-3A signaling, which is involved in regulation of dendrite orientation in cerebral cortex. Neuron 2002;35:907-920.
-
(2002)
Neuron
, vol.35
, pp. 907-920
-
-
Sasaki, Y.1
Cheng, C.2
Uchida, Y.3
-
38
-
-
40149111677
-
Plexin-A3 and plexin-A4 restrict the migration of sympathetic neurons but not their neural crest precursors
-
Waimey KE, Huang PH, Chen M, Cheng HJ. Plexin-A3 and plexin-A4 restrict the migration of sympathetic neurons but not their neural crest precursors. Dev Biol 2008;315:448-458.
-
(2008)
Dev Biol
, vol.315
, pp. 448-458
-
-
Waimey, K.E.1
Huang, P.H.2
Chen, M.3
Cheng, H.J.4
-
39
-
-
0033214312
-
Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors
-
Takahashi T, Fournier A, Nakamura F, et al. Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors. Cell 1999;99:59-69.
-
(1999)
Cell
, vol.99
, pp. 59-69
-
-
Takahashi, T.1
Fournier, A.2
Nakamura, F.3
-
40
-
-
84893020365
-
Rare variants in PLXNA4 and Parkinson's disease
-
Schulte EC, Stahl I, Czamara D, et al. Rare variants in PLXNA4 and Parkinson's disease. PLoS One 2013;8:e79145.
-
(2013)
PLoS One
, vol.8
, pp. e79145
-
-
Schulte, E.C.1
Stahl, I.2
Czamara, D.3
-
41
-
-
79955484414
-
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
-
Hollingworth P, Harold D, Sims R, et al. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet 2011;43:429-435.
-
(2011)
Nat Genet
, vol.43
, pp. 429-435
-
-
Hollingworth, P.1
Harold, D.2
Sims, R.3
-
42
-
-
33846613222
-
The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease
-
Rogaeva E, Meng Y, Lee JH, et al. The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease. Nat Genet 2007;39:168-177.
-
(2007)
Nat Genet
, vol.39
, pp. 168-177
-
-
Rogaeva, E.1
Meng, Y.2
Lee, J.H.3
-
43
-
-
67349153674
-
Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder
-
Schulze TG, Detera-Wadleigh SD, Akula N, et al. Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder. Mol Psychiatry 2009;14:487-491.
-
(2009)
Mol Psychiatry
, vol.14
, pp. 487-491
-
-
Schulze, T.G.1
Detera-Wadleigh, S.D.2
Akula, N.3
-
44
-
-
77954143522
-
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
-
Voight BF, Scott LJ, Steinthorsdottir V, et al. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet 2010;42:579-589.
-
(2010)
Nat Genet
, vol.42
, pp. 579-589
-
-
Voight, B.F.1
Scott, L.J.2
Steinthorsdottir, V.3
-
45
-
-
27644447928
-
Phosphorylation by Rho kinase regulates CRMP-2 activity in growth cones
-
Arimura N, Menager C, Kawano Y, et al. Phosphorylation by Rho kinase regulates CRMP-2 activity in growth cones. Mol Cell Biol 2005;25:9973-9984.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 9973-9984
-
-
Arimura, N.1
Menager, C.2
Kawano, Y.3
-
46
-
-
5644276320
-
Alpha2-chimaerin, cyclin-dependent Kinase 5/p35, and its target collapsin response mediator protein-2 are essential components in semaphorin 3A-induced growth-cone collapse
-
Brown M, Jacobs T, Eickholt B, et al. Alpha2-chimaerin, cyclin-dependent Kinase 5/p35, and its target collapsin response mediator protein-2 are essential components in semaphorin 3A-induced growth-cone collapse. J Neurosci 2004;24:8994-9004.
-
(2004)
J Neurosci
, vol.24
, pp. 8994-9004
-
-
Brown, M.1
Jacobs, T.2
Eickholt, B.3
-
47
-
-
20044370438
-
Semaphorin3A signalling is mediated via sequential Cdk5 and GSK3beta phosphorylation of CRMP2: Implication of common phosphorylating mechanism underlying axon guidance and Alzheimer's disease
-
Uchida Y, Ohshima T, Sasaki Y, et al. Semaphorin3A signalling is mediated via sequential Cdk5 and GSK3beta phosphorylation of CRMP2: implication of common phosphorylating mechanism underlying axon guidance and Alzheimer's disease. Genes Cells 2005;10:165-179.
-
(2005)
Genes Cells
, vol.10
, pp. 165-179
-
-
Uchida, Y.1
Ohshima, T.2
Sasaki, Y.3
|