-
1
-
-
84958012755
-
Comparative circadian metabolomics reveal differential effects of nutritional challenge in the Serum and Liver
-
Abbondante, S., Eckel-Mahan, K. L., Ceglia, N. J., Baldi, P., and Sassone-Corsi, P. (2016). Comparative circadian metabolomics reveal differential effects of nutritional challenge in the Serum and Liver. J. Biol. Chem. 291, 2812-2828. doi: 10.1074/jbc. M115.681130
-
(2016)
J. Biol. Chem
, vol.291
, pp. 2812-2828
-
-
Abbondante, S.1
Eckel-Mahan, K.L.2
Ceglia, N.J.3
Baldi, P.4
Sassone-Corsi, P.5
-
2
-
-
0035970805
-
Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2
-
Abu-Elheiga, L., Matzuk, M. M., Abo-Hashema, K. A., and Wakil, S. J. (2001). Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2. Science 291, 2613-2616. doi: 10.1126/science.1056843
-
(2001)
Science
, vol.291
, pp. 2613-2616
-
-
Abu-Elheiga, L.1
Matzuk, M.M.2
Abo-Hashema, K.A.3
Wakil, S.J.4
-
3
-
-
79952764531
-
Interaction between MYC and MCL1 in the genesis and outcome of non-small-cell lung cancer
-
Allen, T. D., Zhu, C. Q., Jones, K. D., Yanagawa, N., Tsao, M. S., and Bishop, J. M. (2011). Interaction between MYC and MCL1 in the genesis and outcome of non-small-cell lung cancer. Cancer Res. 71, 2212-2221. doi: 10.1158/0008-5472.CAN-10-3590
-
(2011)
Cancer Res
, vol.71
, pp. 2212-2221
-
-
Allen, T.D.1
Zhu, C.Q.2
Jones, K.D.3
Yanagawa, N.4
Tsao, M.S.5
Bishop, J.M.6
-
4
-
-
84941773651
-
MYC disrupts the circadian clock and metabolism in cancer cells
-
Altman, B. J., Hsieh, A. L., Sengupta, A., Krishnanaiah, S. Y., Stine, Z. E., Walton, Z. E., et al. (2015). MYC disrupts the circadian clock and metabolism in cancer cells. Cell Metab. 22, 1009-1019. doi: 10.1016/j.cmet.2015.09.003
-
(2015)
Cell Metab
, vol.22
, pp. 1009-1019
-
-
Altman, B.J.1
Hsieh, A.L.2
Sengupta, A.3
Krishnanaiah, S.Y.4
Stine, Z.E.5
Walton, Z.E.6
-
5
-
-
84982993825
-
From Krebs to clinic: glutamine metabolism to cancer therapy
-
Altman, B. J., Stine, Z. E., and Dang, C. V. (2016). From Krebs to clinic: glutamine metabolism to cancer therapy. Nat. Rev. Cancer 16, 619-634. doi: 10.1038/nrc.2016.71
-
(2016)
Nat. Rev. Cancer
, vol.16
, pp. 619-634
-
-
Altman, B.J.1
Stine, Z.E.2
Dang, C.V.3
-
6
-
-
85013478389
-
-
EMBO Rep
-
Anderton, B., Camarda, R., Balakrishnan, S., Balakrishnan, A., Kohnz, R. A., Lim, L., et al. (2017). MYC-driven inhibition of the glutamate-cysteine ligase promotes glutathione depletion in liver cancer. EMBO Rep. doi: 10.15252/embr.201643068. Available online at: http://embor.embopress.org/content/early/2017/02/20/embr.201643068.long
-
(2017)
MYC-driven inhibition of the glutamate-cysteine ligase promotes glutathione depletion in liver cancer
-
-
Anderton, B.1
Camarda, R.2
Balakrishnan, S.3
Balakrishnan, A.4
Kohnz, R.A.5
Lim, L.6
-
7
-
-
84949207578
-
Systematic pan-cancer analysis of tumour purity
-
Aran, D., Sirota, M., and Butte, A. J. (2015). Systematic pan-cancer analysis of tumour purity. Nat. Commun. 6, 8971. doi: 10.1038/ncomms9971
-
(2015)
Nat. Commun
, vol.6
, pp. 8971
-
-
Aran, D.1
Sirota, M.2
Butte, A.J.3
-
8
-
-
57749187631
-
Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency
-
Barna, M., Pusic, A., Zollo, O., Costa, M., Kondrashov, N., Rego, E., et al. (2008). Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency. Nature 456, 971-975. doi: 10.1038/nature07449
-
(2008)
Nature
, vol.456
, pp. 971-975
-
-
Barna, M.1
Pusic, A.2
Zollo, O.3
Costa, M.4
Kondrashov, N.5
Rego, E.6
-
9
-
-
79952271999
-
The Pim protein kinases regulate energy metabolism and cell growth
-
Beharry, Z., Mahajan, S., Zemskova, M., Lin, Y.-W., Tholanikunnel, B. G., Xia, Z., et al. (2011). The Pim protein kinases regulate energy metabolism and cell growth. Proc. Natl. Acad. Sci. U.S.A. 108, 528-533. doi: 10.1073/pnas.1013214108
-
(2011)
Proc. Natl. Acad. Sci. U.S.A
, vol.108
, pp. 528-533
-
-
Beharry, Z.1
Mahajan, S.2
Zemskova, M.3
Lin, Y.-W.4
Tholanikunnel, B.G.5
Xia, Z.6
-
10
-
-
84951070852
-
Oncogenic Myc induces expression of glutamine synthetase through promoter demethylation
-
Bott, A. J., Peng, I. C., Fan, Y., Faubert, B., Zhao, L., Li, J., et al. (2015). Oncogenic Myc induces expression of glutamine synthetase through promoter demethylation. Cell Metab. 22, 1068-1077. doi: 10.1016/j.cmet.2015.09.025
-
(2015)
Cell Metab
, vol.22
, pp. 1068-1077
-
-
Bott, A.J.1
Peng, I.C.2
Fan, Y.3
Faubert, B.4
Zhao, L.5
Li, J.6
-
11
-
-
84992416469
-
PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer
-
Brasó-Maristany, F., Filosto, S., Catchpole, S., Marlow, R., Quist, J., Francesch-Domenech, E., et al. (2016). PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer. Nat. Med. 22, 1303-1313. doi: 10.1038/nm.4198
-
(2016)
Nat. Med
, vol.22
, pp. 1303-1313
-
-
Brasó-Maristany, F.1
Filosto, S.2
Catchpole, S.3
Marlow, R.4
Quist, J.5
Francesch-Domenech, E.6
-
12
-
-
84923596826
-
A roadmap for interpreting 13C metabolite labeling patterns from cells
-
Buescher, J. M., Antoniewicz, M. R., Boros, L. G., Burgess, S. C., Brunengraber, H., Clish, C. B., et al. (2015). A roadmap for interpreting 13C metabolite labeling patterns from cells. Curr. Opin. Biotechnol. 34, 189-201. doi: 10.1016/j.copbio.2015.02.003
-
(2015)
Curr. Opin. Biotechnol
, vol.34
, pp. 189-201
-
-
Buescher, J.M.1
Antoniewicz, M.R.2
Boros, L.G.3
Burgess, S.C.4
Brunengraber, H.5
Clish, C.B.6
-
13
-
-
84989968256
-
Regulation of OGT by URI in response to glucose confers c-MYC-dependent survival mechanisms
-
Burén, S., Gomes, A. L., Teijeiro, A., Fawal, M.-A., Yilmaz, M., Tummala, K. S., et al. (2016). Regulation of OGT by URI in response to glucose confers c-MYC-dependent survival mechanisms. Cancer Cell 30, 290-307. doi: 10.1016/j.ccell.2016.06.023
-
(2016)
Cancer Cell
, vol.30
, pp. 290-307
-
-
Burén, S.1
Gomes, A.L.2
Teijeiro, A.3
Fawal, M.-A.4
Yilmaz, M.5
Tummala, K.S.6
-
14
-
-
84988569125
-
The current state of cancer metabolism
-
Cairns, R. A., and Mak, T. W. (2016). The current state of cancer metabolism. Nat. Rev. Cancer 16, 613-614. doi: 10.1038/nrc.2016.100
-
(2016)
Nat. Rev. Cancer
, vol.16
, pp. 613-614
-
-
Cairns, R.A.1
Mak, T.W.2
-
15
-
-
57049182539
-
Hepatic stem-like phenotype and interplay of Wnt/β-catenin and Myc signaling in aggressive childhood liver cancer
-
Cairo, S., Armengol, C., De Reyniès, A., Wei, Y., Thomas, E., Renard, C.-A., et al. (2008). Hepatic stem-like phenotype and interplay of Wnt/β-catenin and Myc signaling in aggressive childhood liver cancer. Cancer Cell 14, 471-484. doi: 10.1016/j.ccr.2008.11.002
-
(2008)
Cancer Cell
, vol.14
, pp. 471-484
-
-
Cairo, S.1
Armengol, C.2
De Reyniès, A.3
Wei, Y.4
Thomas, E.5
Renard, C.-A.6
-
16
-
-
13444292555
-
Molecular mechanisms of hepatocarcinogenesis in transgenic mouse models of liver cancer
-
Calvisi, D. F., and Thorgeirsson, S. S. (2005). Molecular mechanisms of hepatocarcinogenesis in transgenic mouse models of liver cancer. Toxicol. Pathol. 33, 181-184. doi: 10.1080/01926230590522095
-
(2005)
Toxicol. Pathol
, vol.33
, pp. 181-184
-
-
Calvisi, D.F.1
Thorgeirsson, S.S.2
-
17
-
-
84960172342
-
Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer
-
Camarda, R., Zhou, A. Y., Kohnz, R. A., Balakrishnan, S., Mahieu, C., Anderton, B., et al. (2016). Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer. Nat. Med. 22, 427-432. doi: 10.1038/nm.4055
-
(2016)
Nat. Med
, vol.22
, pp. 427-432
-
-
Camarda, R.1
Zhou, A.Y.2
Kohnz, R.A.3
Balakrishnan, S.4
Mahieu, C.5
Anderton, B.6
-
18
-
-
84964312498
-
Metabolic characterization of triple negative breast cancer
-
Cao, M. D., Lamichhane, S., Lundgren, S., Bofin, A., Fjøsne, H., Giskeødegård, G. F., et al. (2014). Metabolic characterization of triple negative breast cancer. BMC Cancer 14:941. doi: 10.1186/1471-2407-14-941
-
(2014)
BMC Cancer
, vol.14
, pp. 941
-
-
Cao, M.D.1
Lamichhane, S.2
Lundgren, S.3
Bofin, A.4
Fjøsne, H.5
Giskeødegård, G.F.6
-
19
-
-
79952764351
-
MYC phosphorylation, activation, and tumorigenic potential in hepatocellular carcinoma are regulated by HMG-CoA reductase
-
Cao, Z., Fan-Minogue, H., Bellovin, D. I., Yevtodiyenko, A., Arzeno, J., Yang, Q., et al. (2011). MYC phosphorylation, activation, and tumorigenic potential in hepatocellular carcinoma are regulated by HMG-CoA reductase. Cancer Res. 71, 2286-2297. doi: 10.1158/0008-5472.CAN-10-3367
-
(2011)
Cancer Res
, vol.71
, pp. 2286-2297
-
-
Cao, Z.1
Fan-Minogue, H.2
Bellovin, D.I.3
Yevtodiyenko, A.4
Arzeno, J.5
Yang, Q.6
-
20
-
-
84961219169
-
Glutathione biosynthesis is upregulated at the initiation of MYCN-driven neuroblastoma tumorigenesis
-
Carter, D. R., Sutton, S. K., Pajic, M., Murray, J., Sekyere, E. O., Fletcher, J., et al. (2016). Glutathione biosynthesis is upregulated at the initiation of MYCN-driven neuroblastoma tumorigenesis. Mol. Oncol. 10, 866-878. doi: 10.1016/j.molonc.2016.02.004
-
(2016)
Mol. Oncol
, vol.10
, pp. 866-878
-
-
Carter, D.R.1
Sutton, S.K.2
Pajic, M.3
Murray, J.4
Sekyere, E.O.5
Fletcher, J.6
-
21
-
-
84941344937
-
Metabolic competition in the tumor microenvironment is a driver of cancer progression
-
Chang, C. H., Qiu, J., O'Sullivan, D., Buck, M. D., Noguchi, T., Curtis, J. D., et al. (2015). Metabolic competition in the tumor microenvironment is a driver of cancer progression. Cell 162, 1229-1241. doi: 10.1016/j.cell.2015.08.016
-
(2015)
Cell
, vol.162
, pp. 1229-1241
-
-
Chang, C.H.1
Qiu, J.2
O'Sullivan, D.3
Buck, M.D.4
Noguchi, T.5
Curtis, J.D.6
-
22
-
-
0029049198
-
c-Myc is glycosylated at threonine 58, a known phosphorylation site and a mutational hot spot in lymphomas
-
Chou, T. Y., Hart, G. W., and Dang, C. V. (1995). c-Myc is glycosylated at threonine 58, a known phosphorylation site and a mutational hot spot in lymphomas. J. Biol. Chem. 270, 18961-18965
-
(1995)
J. Biol. Chem
, vol.270
, pp. 18961-18965
-
-
Chou, T.Y.1
Hart, G.W.2
Dang, C.V.3
-
23
-
-
84994092307
-
c-Myc targeted regulators of cell metabolism in a transgenic mouse model of papillary lung adenocarcinoma
-
Ciribilli, Y., Singh, P., Inga, A., and Borlak, J. (2016). c-Myc targeted regulators of cell metabolism in a transgenic mouse model of papillary lung adenocarcinoma. Oncotarget 7, 65514-65539. doi: 10.18632/oncotarget.11804
-
(2016)
Oncotarget
, vol.7
, pp. 65514-65539
-
-
Ciribilli, Y.1
Singh, P.2
Inga, A.3
Borlak, J.4
-
24
-
-
84919936304
-
Acetate dependence of tumors
-
Comerford, S. A., Huang, Z., Du, X., Wang, Y., Cai, L., Witkiewicz, A. K., et al. (2014). Acetate dependence of tumors. Cell 159, 1591-1602. doi: 10.1016/j.cell.2014.11.020
-
(2014)
Cell
, vol.159
, pp. 1591-1602
-
-
Comerford, S.A.1
Huang, Z.2
Du, X.3
Wang, Y.4
Cai, L.5
Witkiewicz, A.K.6
-
25
-
-
84952638835
-
Serum metabolomics analysis reveals changes in signaling lipids in breast cancer patients
-
Cui, M., Wang, Q., and Chen, G. (2016). Serum metabolomics analysis reveals changes in signaling lipids in breast cancer patients. Biomed. Chromatogr. 30, 42-47. doi: 10.1002/bmc.3556
-
(2016)
Biomed. Chromatogr
, vol.30
, pp. 42-47
-
-
Cui, M.1
Wang, Q.2
Chen, G.3
-
26
-
-
84901353547
-
Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer
-
Cunningham, J. T., Moreno, M. V., Lodi, A., Ronen, S. M., and Ruggero, D. (2014). Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer. Cell 157, 1088-1103. doi: 10.1016/j.cell.2014.03.052
-
(2014)
Cell
, vol.157
, pp. 1088-1103
-
-
Cunningham, J.T.1
Moreno, M.V.2
Lodi, A.3
Ronen, S.M.4
Ruggero, D.5
-
27
-
-
84867424108
-
Therapeutic targeting of Myc-reprogrammed cancer cell metabolism
-
Dang, C. V. (2011). Therapeutic targeting of Myc-reprogrammed cancer cell metabolism. Cold Spring Harb. Symp. Quant. Biol. 76, 369-374. doi: 10.1101/sqb.2011.76.011296
-
(2011)
Cold Spring Harb. Symp. Quant. Biol
, vol.76
, pp. 369-374
-
-
Dang, C.V.1
-
28
-
-
84958138936
-
Environment impacts the metabolic dependencies of ras-driven non-small cell lung cancer
-
Davidson, S. M., Papagiannakopoulos, T., Olenchock, B. A., Heyman, J. E., Keibler, M. A., Luengo, A., et al. (2016). Environment impacts the metabolic dependencies of ras-driven non-small cell lung cancer. Cell Metab. 23, 517-528. doi: 10.1016/j.cmet.2016.01.007
-
(2016)
Cell Metab
, vol.23
, pp. 517-528
-
-
Davidson, S.M.1
Papagiannakopoulos, T.2
Olenchock, B.A.3
Heyman, J.E.4
Keibler, M.A.5
Luengo, A.6
-
29
-
-
0035126052
-
c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations
-
D'Cruz, C. M., Gunther, E. J., Boxer, R. B., Hartman, J. L., Sintasath, L., Moody, S. E., et al. (2001). c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations. Nat. Med. 7, 235-239. doi: 10.1038/84691
-
(2001)
Nat. Med
, vol.7
, pp. 235-239
-
-
D'Cruz, C.M.1
Gunther, E.J.2
Boxer, R.B.3
Hartman, J.L.4
Sintasath, L.5
Moody, S.E.6
-
30
-
-
37449024702
-
The biology of cancer: metabolic reprogramming fuels cell growth and proliferation
-
DeBerardinis, R. J., Lum, J. J., Hatzivassiliou, G., and Thompson, C. B. (2008). The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metab. 7, 11-20. doi: 10.1016/j.cmet.2007.10.002
-
(2008)
Cell Metab
, vol.7
, pp. 11-20
-
-
DeBerardinis, R.J.1
Lum, J.J.2
Hatzivassiliou, G.3
Thompson, C.B.4
-
31
-
-
81255135837
-
Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes
-
DeRose, Y. S., Wang, G., Lin, Y., Bernard, P. S., Buys, S. S., Ebbert, M. T., et al. (2011). Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes. Nat. Med. 17, 1514-1520. doi: 10.1038/nm.2454
-
(2011)
Nat. Med
, vol.17
, pp. 1514-1520
-
-
DeRose, Y.S.1
Wang, G.2
Lin, Y.3
Bernard, P.S.4
Buys, S.S.5
Ebbert, M.T.6
-
32
-
-
84943392673
-
PDK1-dependent metabolic reprogramming dictates metastatic potential in breast cancer
-
Dupuy, F., Tabariès, S., Andrzejewski, S., Dong, Z., Blagih, J., Annis, M. G., et al. (2015). PDK1-dependent metabolic reprogramming dictates metastatic potential in breast cancer. Cell Metab. 22, 577-589. doi: 10.1016/j.cmet.2015.08.007
-
(2015)
Cell Metab
, vol.22
, pp. 577-589
-
-
Dupuy, F.1
Tabariès, S.2
Andrzejewski, S.3
Dong, Z.4
Blagih, J.5
Annis, M.G.6
-
33
-
-
84904612313
-
Alteration of the lipid profile in lymphomas induced by MYC overexpression
-
Eberlin, L. S., Gabay, M., Fan, A. C., Gouw, A. M., Tibshirani, R. J., Felsher, D. W., et al. (2014). Alteration of the lipid profile in lymphomas induced by MYC overexpression. Proc. Natl. Acad. Sci. U.S.A. 111, 10450-10455. doi: 10.1073/pnas.1409778111
-
(2014)
Proc. Natl. Acad. Sci. U.S.A
, vol.111
, pp. 10450-10455
-
-
Eberlin, L.S.1
Gabay, M.2
Fan, A.C.3
Gouw, A.M.4
Tibshirani, R.J.5
Felsher, D.W.6
-
34
-
-
0141569009
-
Myc-driven murine prostate cancer shares molecular features with human prostate tumors
-
Ellwood-Yen, K., Graeber, T. G., Wongvipat, J., Iruela-Arispe, M. L., Zhang, J., Matusik, R., et al. (2003). Myc-driven murine prostate cancer shares molecular features with human prostate tumors. Cancer Cell 4, 223-238. doi: 10.1016/S1535-6108(03)00197-1
-
(2003)
Cancer Cell
, vol.4
, pp. 223-238
-
-
Ellwood-Yen, K.1
Graeber, T.G.2
Wongvipat, J.3
Iruela-Arispe, M.L.4
Zhang, J.5
Matusik, R.6
-
35
-
-
0033180211
-
Reversible tumorigenesis by MYC in hematopoietic lineages
-
Felsher, D. W., and Bishop, J. M. (1999). Reversible tumorigenesis by MYC in hematopoietic lineages. Mol. Cell 4, 199-207. doi: 10.1016/S1097-2765(00)80367-6
-
(1999)
Mol. Cell
, vol.4
, pp. 199-207
-
-
Felsher, D.W.1
Bishop, J.M.2
-
36
-
-
40449093361
-
Recommendations on the use of 18F-FDG PET in oncology
-
Fletcher, J. W., Djulbegovic, B., Soares, H. P., Siegel, B. A., Lowe, V. J., Lyman, G. H., et al. (2008). Recommendations on the use of 18F-FDG PET in oncology. J. Nucl. Med. 49, 480-508. doi: 10.2967/jnumed.107.047787
-
(2008)
J. Nucl. Med
, vol.49
, pp. 480-508
-
-
Fletcher, J.W.1
Djulbegovic, B.2
Soares, H.P.3
Siegel, B.A.4
Lowe, V.J.5
Lyman, G.H.6
-
37
-
-
84887045362
-
Metabolic targets for cancer therapy
-
Galluzzi, L., Kepp, O., Vander Heiden, M. G., and Kroemer, G. (2013). Metabolic targets for cancer therapy. Nat. Rev. Drug Discov. 12, 829-846. doi: 10.1038/nrd4145
-
(2013)
Nat. Rev. Drug Discov
, vol.12
, pp. 829-846
-
-
Galluzzi, L.1
Kepp, O.2
Vander Heiden, M.G.3
Kroemer, G.4
-
38
-
-
64749116346
-
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
-
Gao, P., Tchernyshyov, I., Chang, T.-C., Lee, Y.-S., Kita, K., Ochi, T., et al. (2009). c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism. Nature 458, 762-765. doi: 10.1038/nature07823
-
(2009)
Nature
, vol.458
, pp. 762-765
-
-
Gao, P.1
Tchernyshyov, I.2
Chang, T.-C.3
Lee, Y.-S.4
Kita, K.5
Ochi, T.6
-
39
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan, D., and Weinberg, R. A. (2011). Hallmarks of cancer: the next generation. Cell 144, 646-674. doi: 10.1016/j.cell.2011.02.013
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
40
-
-
0023854161
-
The E mu-myc transgenic mouse
-
Harris, A. W., Pinkert, C. A., Crawford, M., Langdon, W. Y., Brinster, R. L., and Adams, J. M. (1988). The E mu-myc transgenic mouse. A model for high-incidence spontaneous lymphoma and leukemia of early B cells. J. Exp. Med. 167, 353-371
-
(1988)
A model for high-incidence spontaneous lymphoma and leukemia of early B cells. J. Exp. Med
, vol.167
, pp. 353-371
-
-
Harris, A.W.1
Pinkert, C.A.2
Crawford, M.3
Langdon, W.Y.4
Brinster, R.L.5
Adams, J.M.6
-
41
-
-
84870546460
-
ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth
-
Hart, L. S., Cunningham, J. T., Datta, T., Dey, S., Tameire, F., Lehman, S. L., et al. (2012). ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth. J. Clin. Invest. 122, 4621-4634. doi: 10.1172/JCI62973
-
(2012)
J. Clin. Invest
, vol.122
, pp. 4621-4634
-
-
Hart, L.S.1
Cunningham, J.T.2
Datta, T.3
Dey, S.4
Tameire, F.5
Lehman, S.L.6
-
42
-
-
84988416810
-
Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?
-
Hay, N. (2016). Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy? Nat. Rev. Cancer 16, 1-15. doi: 10.1038/nrc.2016.77
-
(2016)
Nat. Rev. Cancer
, vol.16
, pp. 1-15
-
-
Hay, N.1
-
43
-
-
84922178023
-
Reduced expression of MYC increases longevity and enhances healthspan
-
Hofmann, J. W., Zhao, X., De Cecco, M., Peterson, A. L., Pagliaroli, L., Manivannan, J., et al. (2015). Reduced expression of MYC increases longevity and enhances healthspan. Cell 160, 477-488. doi: 10.1016/j.cell.2014.12.016
-
(2015)
Cell
, vol.160
, pp. 477-488
-
-
Hofmann, J.W.1
Zhao, X.2
De Cecco, M.3
Peterson, A.L.4
Pagliaroli, L.5
Manivannan, J.6
-
44
-
-
84992376478
-
PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression
-
Horiuchi, D., Camarda, R., Zhou, A. Y., Yau, C., Momcilovic, O., Balakrishnan, S., et al. (2016). PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression. Nat. Med. 22, 1321-1329. doi: 10.1038/nm.4213
-
(2016)
Nat. Med
, vol.22
, pp. 1321-1329
-
-
Horiuchi, D.1
Camarda, R.2
Zhou, A.Y.3
Yau, C.4
Momcilovic, O.5
Balakrishnan, S.6
-
45
-
-
84861735363
-
MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition
-
Horiuchi, D., Kusdra, L., Huskey, N. E., Chandriani, S., Lenburg, M. E., Gonzalez-Angulo, A. M., et al. (2012). MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition. J. Exp. Med. 209, 679-696. doi: 10.1084/jem.20111512
-
(2012)
J. Exp. Med
, vol.209
, pp. 679-696
-
-
Horiuchi, D.1
Kusdra, L.2
Huskey, N.E.3
Chandriani, S.4
Lenburg, M.E.5
Gonzalez-Angulo, A.M.6
-
46
-
-
84955560430
-
Phosphoinositide 3-kinase regulates glycolysis through mobilization of aldolase from the actin cytoskeleton
-
Hu, H., Juvekar, A., Lyssiotis, C. A., Lien, E. C., Albeck, J. G., Oh, D., et al. (2016). Phosphoinositide 3-kinase regulates glycolysis through mobilization of aldolase from the actin cytoskeleton. Cell 164, 433-446. doi: 10.1016/j.cell.2015.12.042
-
(2016)
Cell
, vol.164
, pp. 433-446
-
-
Hu, H.1
Juvekar, A.2
Lyssiotis, C.A.3
Lien, E.C.4
Albeck, J.G.5
Oh, D.6
-
47
-
-
79960006190
-
13C-pyruvate imaging reveals alterations in glycolysis that precede c-Myc-induced tumor formation and regression
-
Hu, S., Balakrishnan, A., Bok, R. A., Anderton, B., Larson, P. E., Nelson, S. J., et al. (2011). 13C-pyruvate imaging reveals alterations in glycolysis that precede c-Myc-induced tumor formation and regression. Cell Metab. 14, 131-142. doi: 10.1016/j.cmet.2011.04.012
-
(2011)
Cell Metab
, vol.14
, pp. 131-142
-
-
Hu, S.1
Balakrishnan, A.2
Bok, R.A.3
Anderton, B.4
Larson, P.E.5
Nelson, S.J.6
-
48
-
-
84882632229
-
Metabolic characterization of hepatocellular carcinoma using nontargeted tissue metabolomics
-
Huang, Q., Tan, Y., Yin, P., Ye, G., Gao, P., Lu, X., et al. (2013). Metabolic characterization of hepatocellular carcinoma using nontargeted tissue metabolomics. Cancer Res. 73, 4992-5002. doi: 10.1158/0008-5472.CAN-13-0308
-
(2013)
Cancer Res
, vol.73
, pp. 4992-5002
-
-
Huang, Q.1
Tan, Y.2
Yin, P.3
Ye, G.4
Gao, P.5
Lu, X.6
-
49
-
-
84938568011
-
Hypoxia Induces Production of L-2-Hydroxyglutarate
-
Intlekofer, A. M., DeMatteo, R. G., Venneti, S., Finley, L. W., Lu, C., Judkins, A. R., et al. (2015). Hypoxia Induces Production of L-2-Hydroxyglutarate. Cell Metab. 22, 304-311. doi: 10.1016/j.cmet.2015.06.023
-
(2015)
Cell Metab
, vol.22
, pp. 304-311
-
-
Intlekofer, A.M.1
DeMatteo, R.G.2
Venneti, S.3
Finley, L.W.4
Lu, C.5
Judkins, A.R.6
-
50
-
-
84912139595
-
Metabolic profile of triple-negative breast cancer in African-American women reveals potential biomarkers of aggressive disease
-
Kanaan, Y. M., Sampey, B. P., Beyene, D., Esnakula, A. K., Naab, T. J., Ricks-Santi, L. J., et al. (2014). Metabolic profile of triple-negative breast cancer in African-American women reveals potential biomarkers of aggressive disease. Cancer Genomics Proteomics 11, 279-294
-
(2014)
Cancer Genomics Proteomics
, vol.11
, pp. 279-294
-
-
Kanaan, Y.M.1
Sampey, B.P.2
Beyene, D.3
Esnakula, A.K.4
Naab, T.J.5
Ricks-Santi, L.J.6
-
51
-
-
66149152693
-
Central role of c-Myc during malignant conversion in human hepatocarcinogenesis
-
Kaposi-Novak, P., Libbrecht, L., Woo, H. G., Lee, Y. H., Sears, N. C., Conner, E. A., et al. (2009). Central role of c-Myc during malignant conversion in human hepatocarcinogenesis. Cancer Res. 69, 2775-2782. doi: 10.1158/0008-5472.CAN-08-3357
-
(2009)
Cancer Res
, vol.69
, pp. 2775-2782
-
-
Kaposi-Novak, P.1
Libbrecht, L.2
Woo, H.G.3
Lee, Y.H.4
Sears, N.C.5
Conner, E.A.6
-
52
-
-
35649014840
-
Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1
-
Kim, J. W., Gao, P., Liu, Y.-C., Semenza, G. L., and Dang, C. V. (2007). Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1. Mol. Cell. Biol. 27, 7381-7393. doi: 10.1128/MCB.00440-07
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 7381-7393
-
-
Kim, J.W.1
Gao, P.2
Liu, Y.-C.3
Semenza, G.L.4
Dang, C.V.5
-
53
-
-
84877028141
-
Comprehensive molecular portraits of human breast tumours
-
Koboldt, D. C., Fulton, R. S., McLellan, M. D., Schmidt, H., Kalicki-Veizer, J., McMichael, J. F., et al. (2012). Comprehensive molecular portraits of human breast tumours. Nature 490, 61-70. doi: 10.1038/nature11412
-
(2012)
Nature
, vol.490
, pp. 61-70
-
-
Koboldt, D.C.1
Fulton, R.S.2
McLellan, M.D.3
Schmidt, H.4
Kalicki-Veizer, J.5
McMichael, J.F.6
-
54
-
-
66449136951
-
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model
-
Kota, J., Chivukula, R. R., O'Donnell, K. A., Wentzel, E. A., Montgomery, C. L., Hwang, H. W., et al. (2009). Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 137, 1005-1017. doi: 10.1016/j.cell.2009.04.021
-
(2009)
Cell
, vol.137
, pp. 1005-1017
-
-
Kota, J.1
Chivukula, R.R.2
O'Donnell, K.A.3
Wentzel, E.A.4
Montgomery, C.L.5
Hwang, H.W.6
-
55
-
-
84942370919
-
MYC: connecting selective transcriptional control to global RNA production
-
Kress, T. R., Sabò, A., and Amati, B. (2015). MYC: connecting selective transcriptional control to global RNA production. Nat. Rev. Cancer 15, 593-607. doi: 10.1038/nrc3984
-
(2015)
Nat. Rev. Cancer
, vol.15
, pp. 593-607
-
-
Kress, T.R.1
Sabò, A.2
Amati, B.3
-
56
-
-
79951507755
-
Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research
-
Kurhanewicz, J., Vigneron, D. B., Brindle, K., Chekmenev, E. Y., Comment, A., Cunningham, C. H., et al. (2011). Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research. Neoplasia 13, 81-97. doi: 10.1593/neo.101102
-
(2011)
Neoplasia
, vol.13
, pp. 81-97
-
-
Kurhanewicz, J.1
Vigneron, D.B.2
Brindle, K.3
Chekmenev, E.Y.4
Comment, A.5
Cunningham, C.H.6
-
57
-
-
84943143136
-
Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells
-
Lawson, D. A., Bhakta, N. R., Kessenbrock, K., Prummel, K. D., Yu, Y., Takai, K., et al. (2015). Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells. Nature 526, 131-135. doi: 10.1038/nature15260
-
(2015)
Nature
, vol.526
, pp. 131-135
-
-
Lawson, D.A.1
Bhakta, N.R.2
Kessenbrock, K.3
Prummel, K.D.4
Yu, Y.5
Takai, K.6
-
58
-
-
84994131487
-
Systematic functional characterization of resistance to PI3K inhibition in breast cancer
-
Le, X., Antony, R., Razavi, P., Treacy, D. J., Luo, F., Ghandi, M., et al. (2016). Systematic functional characterization of resistance to PI3K inhibition in breast cancer. Cancer Discov. 6, 1134-1147. doi: 10.1158/2159-8290.CD-16-0305
-
(2016)
Cancer Discov
, vol.6
, pp. 1134-1147
-
-
Le, X.1
Antony, R.2
Razavi, P.3
Treacy, D.J.4
Luo, F.5
Ghandi, M.6
-
59
-
-
84920616812
-
PGC-1a mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasi
-
(1003)
-
LeBleu, V. S., O'Connell, J. T., Gonzalez Herrera, K. N., Wikman, H., Pantel, K., Haigis, M. C., et al. (2014). PGC-1a mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis. Nat. Cell Biol. 16, 992-1003, 1-15. doi: 10.1038/ncb3039
-
(2014)
Nat. Cell Biol
, vol.16
, Issue.992
, pp. 1-15
-
-
LeBleu, V.S.1
O'Connell, J.T.2
Gonzalez Herrera, K.N.3
Wikman, H.4
Pantel, K.5
Haigis, M.C.6
-
60
-
-
21744442902
-
Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis
-
Li, F., Wang, Y., Zeller, K. I., Potter, J. J., Wonsey, D. R., O'Donnell, K., et al. (2005). Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis. Mol. Cell. Biol. 25, 6225-6234. doi: 10.1128/MCB.25.14.6225-6234.2005
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 6225-6234
-
-
Li, F.1
Wang, Y.2
Zeller, K.I.3
Potter, J.J.4
Wonsey, D.R.5
O'Donnell, K.6
-
61
-
-
83755168277
-
PET imaging of glutaminolysis in tumors by 18F-(2S, 4R)4-fluoroglutamine
-
Lieberman, B. P., Ploessl, K., Wang, L., Qu, W., Zha, Z., Wise, D. R., et al. (2011). PET imaging of glutaminolysis in tumors by 18F-(2S, 4R)4-fluoroglutamine. J. Nucl. Med. 52, 1947-1955. doi: 10.2967/jnumed.111.093815
-
(2011)
J. Nucl. Med
, vol.52
, pp. 1947-1955
-
-
Lieberman, B.P.1
Ploessl, K.2
Wang, L.3
Qu, W.4
Zha, Z.5
Wise, D.R.6
-
62
-
-
84894728095
-
MicroRNA-494 within an oncogenic microRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of mutated in colorectal cancer
-
Lim, L., Balakrishnan, A., Huskey, N., Jones, K. D., Jodari, M., Ng, R., et al. (2014). MicroRNA-494 within an oncogenic microRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of mutated in colorectal cancer. Hepatology 59, 202-215. doi: 10.1002/hep.26662
-
(2014)
Hepatology
, vol.59
, pp. 202-215
-
-
Lim, L.1
Balakrishnan, A.2
Huskey, N.3
Jones, K.D.4
Jodari, M.5
Ng, R.6
-
63
-
-
79952772664
-
Association of FABP5 expression with poor survival in triple-negative breast cancer: implication for retinoic acid therapy
-
Liu, R. Z., Graham, K., Glubrecht, D. D., Germain, D. R., Mackey, J. R., and Godbout, R. (2011). Association of FABP5 expression with poor survival in triple-negative breast cancer: implication for retinoic acid therapy. Am. J. Pathol. 178, 997-1008. doi: 10.1016/j.ajpath.2010.11.075
-
(2011)
Am. J. Pathol
, vol.178
, pp. 997-1008
-
-
Liu, R.Z.1
Graham, K.2
Glubrecht, D.D.3
Germain, D.R.4
Mackey, J.R.5
Godbout, R.6
-
64
-
-
84901027155
-
NMR and LC/MS-based global metabolomics to identify serum biomarkers differentiating hepatocellular carcinoma from liver cirrhosis
-
Liu, Y., Hong, Z., Tan, G., Dong, X., Yang, G., Zhao, L., et al. (2014). NMR and LC/MS-based global metabolomics to identify serum biomarkers differentiating hepatocellular carcinoma from liver cirrhosis. Int. J. Cancer 135, 658-668. doi: 10.1002/ijc.28706
-
(2014)
Int. J. Cancer
, vol.135
, pp. 658-668
-
-
Liu, Y.1
Hong, Z.2
Tan, G.3
Dong, X.4
Yang, G.5
Zhao, L.6
-
65
-
-
84869753078
-
Sensitivity of human lung adenocarcinoma cell lines to targeted inhibition of BET epigenetic signaling proteins
-
Lockwood, W. W., Zejnullahu, K., Bradner, J. E., and Varmus, H. (2012). Sensitivity of human lung adenocarcinoma cell lines to targeted inhibition of BET epigenetic signaling proteins. Proc. Natl. Acad. Sci. U.S.A. 109, 19408-19413. doi: 10.1073/pnas.1216363109
-
(2012)
Proc. Natl. Acad. Sci. U.S.A
, vol.109
, pp. 19408-19413
-
-
Lockwood, W.W.1
Zejnullahu, K.2
Bradner, J.E.3
Varmus, H.4
-
66
-
-
0038271762
-
Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT model
-
Majumder, P. K., Yeh, J. J., George, D. J., Febbo, P. G., Kum, J., Xue, Q., et al. (2003). Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT model. Proc. Natl. Acad. Sci. U.S.A. 100, 7841-7846. doi: 10.1073/pnas.1232229100
-
(2003)
Proc. Natl. Acad. Sci. U.S.A
, vol.100
, pp. 7841-7846
-
-
Majumder, P.K.1
Yeh, J.J.2
George, D.J.3
Febbo, P.G.4
Kum, J.5
Xue, Q.6
-
67
-
-
84919903877
-
Acetate is a bioenergetic substrate for human glioblastoma and brain metastases
-
Mashimo, T., Pichumani, K., Vemireddy, V., Hatanpaa, K. J., Singh, D. K., Sirasanagandla, S., et al. (2014). Acetate is a bioenergetic substrate for human glioblastoma and brain metastases. Cell 159, 1603-1614. doi: 10.1016/j.cell.2014.11.025
-
(2014)
Cell
, vol.159
, pp. 1603-1614
-
-
Mashimo, T.1
Pichumani, K.2
Vemireddy, V.3
Hatanpaa, K.J.4
Singh, D.K.5
Sirasanagandla, S.6
-
68
-
-
84923186422
-
Famine versus feast: understanding the metabolism of tumors in vivo
-
Mayers, J. R., and Vander Heiden, M. G. (2015). Famine versus feast: understanding the metabolism of tumors in vivo. Trends Biochem. Sci. 40, 130-140. doi: 10.1016/j.tibs.2015.01.004
-
(2015)
Trends Biochem. Sci
, vol.40
, pp. 130-140
-
-
Mayers, J.R.1
Vander Heiden, M.G.2
-
70
-
-
84910074157
-
Exploring metabolic pathways and regulation through functional chemoproteomic and metabolomic platforms
-
Medina-Cleghorn, D., and Nomura, D. K. (2014). Exploring metabolic pathways and regulation through functional chemoproteomic and metabolomic platforms. Chem. Biol. 21, 1171-1184. doi: 10.1016/j.chembiol.2014.07.007
-
(2014)
Chem. Biol
, vol.21
, pp. 1171-1184
-
-
Medina-Cleghorn, D.1
Nomura, D.K.2
-
71
-
-
56749184298
-
Reflecting on 25 years with MYC
-
Meyer, N., and Penn, L. Z. (2008). Reflecting on 25 years with MYC. Nat. Rev. Cancer 8, 976-990. doi: 10.1038/nrc2231
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 976-990
-
-
Meyer, N.1
Penn, L.Z.2
-
72
-
-
84883879044
-
Metabolic imaging of patients with prostate cancer using hyperpolarized [1-13C]pyruvate
-
Nelson, S. J., Kurhanewicz, J., Vigneron, D. B., Larson, P. E. Z., Harzstark, A. L., Ferrone, M., et al. (2013). Metabolic imaging of patients with prostate cancer using hyperpolarized [1-13C]pyruvate. Sci. Transl. Med. 5, 198ra108. doi: 10.1126/scitranslmed.3006070
-
(2013)
Sci. Transl. Med
, vol.5
-
-
Nelson, S.J.1
Kurhanewicz, J.2
Vigneron, D.B.3
Larson, P.E.Z.4
Harzstark, A.L.5
Ferrone, M.6
-
73
-
-
81255157465
-
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
-
Nieman, K. M., Kenny, H. A., Penicka, C. V., Ladanyi, A., Buell-Gutbrod, R., Zillhardt, M. R., et al. (2011). Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth. Nat. Med. 17, 1498-1503. doi: 10.1038/nm.2492
-
(2011)
Nat. Med
, vol.17
, pp. 1498-1503
-
-
Nieman, K.M.1
Kenny, H.A.2
Penicka, C.V.3
Ladanyi, A.4
Buell-Gutbrod, R.5
Zillhardt, M.R.6
-
74
-
-
84938599103
-
Hypoxia-mediated increases in l-2-hydroxyglutarate coordinate the metabolic response to reductive stress
-
Oldham, W. M., Clish, C. B., Yang, Y., and Loscalzo, J. (2015). Hypoxia-mediated increases in l-2-hydroxyglutarate coordinate the metabolic response to reductive stress. Cell Metab. 22, 291-303. doi: 10.1016/j.cmet.2015.06.021
-
(2015)
Cell Metab
, vol.22
, pp. 291-303
-
-
Oldham, W.M.1
Clish, C.B.2
Yang, Y.3
Loscalzo, J.4
-
75
-
-
84875995108
-
Carnitine-acyltransferase system inhibition, cancer cell death, and prevention of myc-induced lymphomagenesis
-
Pacilli, A., Calienni, M., Margarucci, S., D'Apolito, M., Petillo, O., Rocchi, L., et al. (2013). Carnitine-acyltransferase system inhibition, cancer cell death, and prevention of myc-induced lymphomagenesis. J. Natl. Cancer Inst. 105, 489-498. doi: 10.1093/jnci/djt030
-
(2013)
J. Natl. Cancer Inst
, vol.105
, pp. 489-498
-
-
Pacilli, A.1
Calienni, M.2
Margarucci, S.3
D'Apolito, M.4
Petillo, O.5
Rocchi, L.6
-
76
-
-
79960954452
-
18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancers
-
Palaskas, N., Larson, S. M., Schultz, N., Komisopoulou, E., Wong, J., Rohle, D., et al. (2011). 18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancers. Cancer Res. 71, 5164-5174. doi: 10.1158/0008-5472.CAN-10-4633
-
(2011)
Cancer Res
, vol.71
, pp. 5164-5174
-
-
Palaskas, N.1
Larson, S.M.2
Schultz, N.3
Komisopoulou, E.4
Wong, J.5
Rohle, D.6
-
77
-
-
84960423377
-
Fatty acid oxidation-driven Src links mitochondrial energy reprogramming and oncogenic properties in triple-negative breast cancer
-
Park, J. H., Vithayathil, S., Kumar, S., Sung, P.-L., Dobrolecki, L. E., Putluri, V., et al. (2016). Fatty acid oxidation-driven Src links mitochondrial energy reprogramming and oncogenic properties in triple-negative breast cancer. Cell Rep. 14, 2154-2165. doi: 10.1016/j.celrep.2016.02.004
-
(2016)
Cell Rep
, vol.14
, pp. 2154-2165
-
-
Park, J.H.1
Vithayathil, S.2
Kumar, S.3
Sung, P.-L.4
Dobrolecki, L.E.5
Putluri, V.6
-
78
-
-
85016165255
-
Targeting metastasis-initiating cells through the fatty acid receptor CD36
-
Pascual, G., Avgustinova, A., Mejetta, S., Martín, M., Castellanos, A., Attolini, C. S.-O., et al. (2016). Targeting metastasis-initiating cells through the fatty acid receptor CD36. Nature 541, 41-45. doi: 10.1038/nature20791
-
(2016)
Nature
, vol.541
, pp. 41-45
-
-
Pascual, G.1
Avgustinova, A.2
Mejetta, S.3
Martín, M.4
Castellanos, A.5
Attolini, C.S.-O.6
-
79
-
-
84877342651
-
Characterization of MYC-induced tumorigenesis by in situ lipid profiling
-
Perry, R. H., Bellovin, D. I., Shroff, E. H., Ismail, A. I., Zabuawala, T., Felsher, D. W., et al. (2013). Characterization of MYC-induced tumorigenesis by in situ lipid profiling. Anal. Chem. 85, 4259-4262. doi: 10.1021/ac400479j
-
(2013)
Anal. Chem
, vol.85
, pp. 4259-4262
-
-
Perry, R.H.1
Bellovin, D.I.2
Shroff, E.H.3
Ismail, A.I.4
Zabuawala, T.5
Felsher, D.W.6
-
80
-
-
84887398348
-
Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts
-
Pfefferle, A. D., Herschkowitz, J. I., Usary, J., Harrell, J. C., Spike, B. T., Adams, J. R., et al. (2013). Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts. Genome Biol. 14:R125. doi: 10.1186/gb-2013-14-11-r125
-
(2013)
Genome Biol
, vol.14
-
-
Pfefferle, A.D.1
Herschkowitz, J.I.2
Usary, J.3
Harrell, J.C.4
Spike, B.T.5
Adams, J.R.6
-
81
-
-
84918573255
-
AKT1 and MYC induce distinctive metabolic fingerprints in human prostate cancer
-
Priolo, C., Pyne, S., Rose, J., Regan, E. R., Zadra, G., Photopoulos, C., et al. (2014). AKT1 and MYC induce distinctive metabolic fingerprints in human prostate cancer. Cancer Res. 74, 7198-7204. doi: 10.1158/0008-5472.CAN-14-1490
-
(2014)
Cancer Res
, vol.74
, pp. 7198-7204
-
-
Priolo, C.1
Pyne, S.2
Rose, J.3
Regan, E.R.4
Zadra, G.5
Photopoulos, C.6
-
82
-
-
7744220635
-
MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer
-
Shachaf, C. M., Kopelman, A. M., Arvanitis, C., Karlsson, A., Beer, S., Mandl, S., et al. (2004). MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer. Nature 431, 1112-1117. doi: 10.1038/nature03043
-
(2004)
Nature
, vol.431
, pp. 1112-1117
-
-
Shachaf, C.M.1
Kopelman, A.M.2
Arvanitis, C.3
Karlsson, A.4
Beer, S.5
Mandl, S.6
-
83
-
-
34948863375
-
Inhibition of HMGcoA reductase by atorvastatin prevents and reverses MYC-induced lymphomagenesis
-
Shachaf, C. M., Perez, O. D., Youssef, S., Fan, A. C., Elchuri, S., Goldstein, M. J., et al. (2007). Inhibition of HMGcoA reductase by atorvastatin prevents and reverses MYC-induced lymphomagenesis. Blood 110, 2674-2684. doi: 10.1182/blood-2006-09-048033
-
(2007)
Blood
, vol.110
, pp. 2674-2684
-
-
Shachaf, C.M.1
Perez, O.D.2
Youssef, S.3
Fan, A.C.4
Elchuri, S.5
Goldstein, M.J.6
-
84
-
-
0030921103
-
c-Myc transactivation of LDH-A: implications for tumor metabolism and growth
-
Shim, H., Dolde, C., Lewis, B. C., Wu, C. S., Dang, G., Jungmann, R. A., et al. (1997). c-Myc transactivation of LDH-A: implications for tumor metabolism and growth. Proc. Natl. Acad. Sci. U.S.A. 94, 6658-6663. doi: 10.1073/pnas.94.13.6658
-
(1997)
Proc. Natl. Acad. Sci. U.S.A
, vol.94
, pp. 6658-6663
-
-
Shim, H.1
Dolde, C.2
Lewis, B.C.3
Wu, C.S.4
Dang, G.5
Jungmann, R.A.6
-
85
-
-
84930216252
-
MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism
-
Shroff, E. H., Eberlin, L. S., Dang, V. M., Gouw, A. M., Gabay, M., Adam, S. J., et al. (2015). MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism. Proc. Natl. Acad. Sci. U.S.A. 112, 6539-6544. doi: 10.1073/pnas.1507228112
-
(2015)
Proc. Natl. Acad. Sci. U.S.A
, vol.112
, pp. 6539-6544
-
-
Shroff, E.H.1
Eberlin, L.S.2
Dang, V.M.3
Gouw, A.M.4
Gabay, M.5
Adam, S.J.6
-
86
-
-
79952851120
-
Myc, mondo, and metabolism
-
Sloan, E. J., and Ayer, D. E. (2010). Myc, mondo, and metabolism. Genes Cancer 1, 587-596. doi: 10.1177/1947601910377489
-
(2010)
Genes Cancer
, vol.1
, pp. 587-596
-
-
Sloan, E.J.1
Ayer, D.E.2
-
87
-
-
84943257841
-
MYC, metabolism, and cancer
-
Stine, Z. E., Walton, Z. E., Altman, B. J., Hsieh, A. L., and Dang, C. V. (2015). MYC, metabolism, and cancer. Cancer Discov. 5, 1024-1039. doi: 10.1158/2159-8290.CD-15-0507
-
(2015)
Cancer Discov
, vol.5
, pp. 1024-1039
-
-
Stine, Z.E.1
Walton, Z.E.2
Altman, B.J.3
Hsieh, A.L.4
Dang, C.V.5
-
88
-
-
84892939615
-
MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis
-
Terunuma, A., Putluri, N., Mishra, P., Mathé, E. A., Dorsey, T. H., Yi, M., et al. (2014). MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis. J. Clin. Invest. 124, 398-412. doi: 10.1172/JCI71180
-
(2014)
J. Clin. Invest
, vol.124
, pp. 398-412
-
-
Terunuma, A.1
Putluri, N.2
Mishra, P.3
Mathé, E.A.4
Dorsey, T.H.5
Yi, M.6
-
89
-
-
33746407121
-
Genomic progression in mouse models for liver tumors
-
Tward, A. D., Jones, K. D., Yant, S., Kay, M. A., Wang, R., and Bishop, J. M. (2005). Genomic progression in mouse models for liver tumors. Cold Spring Harb. Symp. Quant. Biol. 70, 217-224. doi: 10.1101/sqb.2005.70.058
-
(2005)
Cold Spring Harb. Symp. Quant. Biol
, vol.70
, pp. 217-224
-
-
Tward, A.D.1
Jones, K.D.2
Yant, S.3
Kay, M.A.4
Wang, R.5
Bishop, J.M.6
-
90
-
-
66249108601
-
Understanding the Warburg effect: the metabolic requirements of cell proliferation
-
Vander Heiden, M. G., Cantley, L. C., and Thompson, C. B. (2009). Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324, 1029-1033. doi: 10.1126/science.1160809
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
91
-
-
84939881422
-
Impact of MYC in regulation of tumor cell metabolism
-
Wahlström, T., and Henriksson, M. A. (2015). Impact of MYC in regulation of tumor cell metabolism. Biochim. Biophys. Acta. 1849, 563-569. doi: 10.1016/j.bbagrm.2014.07.004
-
(2015)
Biochim. Biophys. Acta
, vol.1849
, pp. 563-569
-
-
Wahlström, T.1
Henriksson, M.A.2
-
92
-
-
85006351483
-
Coordinated activities of multiple Myc-dependent and Myc-independent biosynthetic pathways in hepatoblastoma
-
Wang, H., Lu, J., Edmunds, L. R., Kulkarni, S., Dolezal, J., Tao, J., et al. (2016). Coordinated activities of multiple Myc-dependent and Myc-independent biosynthetic pathways in hepatoblastoma. J. Biol. Chem. 291, 26241-26251. doi: 10.1074/jbc.m116.754218
-
(2016)
J. Biol. Chem
, vol.291
, pp. 26241-26251
-
-
Wang, H.1
Lu, J.2
Edmunds, L.R.3
Kulkarni, S.4
Dolezal, J.5
Tao, J.6
-
93
-
-
0035947770
-
Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice
-
Wang, R., Ferrell, L. D., Faouzi, S., Maher, J. J., and Bishop, J. M. (2001). Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice. J. Cell Biol. 153, 1023-1034. doi: 10.1083/jcb.153.5.1023
-
(2001)
J. Cell Biol
, vol.153
, pp. 1023-1034
-
-
Wang, R.1
Ferrell, L.D.2
Faouzi, S.3
Maher, J.J.4
Bishop, J.M.5
-
94
-
-
0030999641
-
Targeted expression of MYCN causes neuroblastoma in transgenic mice
-
Weiss, W. A., Aldape, K., Mohapatra, G., Feuerstein, B. G., and Bishop, J. M. (1997). Targeted expression of MYCN causes neuroblastoma in transgenic mice. EMBO J. 16, 2985-2995. doi: 10.1093/emboj/16.11.2985
-
(1997)
EMBO J
, vol.16
, pp. 2985-2995
-
-
Weiss, W.A.1
Aldape, K.2
Mohapatra, G.3
Feuerstein, B.G.4
Bishop, J.M.5
-
95
-
-
84938970748
-
Grade-dependent metabolic reprogramming in kidney cancer revealed by combined proteomics and metabolomics analysis
-
Wettersten, H. I., Hakimi, A. A., Morin, D., Bianchi, C., Johnstone, M. E., Donohoe, D. R., et al. (2015). Grade-dependent metabolic reprogramming in kidney cancer revealed by combined proteomics and metabolomics analysis. Cancer Res. 75, 2541-2552. doi: 10.1158/0008-5472.CAN-14-1703
-
(2015)
Cancer Res
, vol.75
, pp. 2541-2552
-
-
Wettersten, H.I.1
Hakimi, A.A.2
Morin, D.3
Bianchi, C.4
Johnstone, M.E.5
Donohoe, D.R.6
-
96
-
-
84930392977
-
Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis
-
Xiang, Y., Stine, Z. E., Xia, J., Lu, Y., O'Connor, R. S., Altman, B. J., et al. (2015). Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis. J. Clin. Invest. 125, 2293-2306. doi: 10.1172/JCI75836
-
(2015)
J. Clin. Invest
, vol.125
, pp. 2293-2306
-
-
Xiang, Y.1
Stine, Z.E.2
Xia, J.3
Lu, Y.4
O'Connor, R.S.5
Altman, B.J.6
-
97
-
-
84863011452
-
The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type
-
Yuneva, M. O., Fan, T. W., Allen, T. D., Higashi, R. M., Ferraris, D. V., Tsukamoto, T., et al. (2012). The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type. Cell Metab. 15, 157-170. doi: 10.1016/j.cmet.2011.12.015
-
(2012)
Cell Metab
, vol.15
, pp. 157-170
-
-
Yuneva, M.O.1
Fan, T.W.2
Allen, T.D.3
Higashi, R.M.4
Ferraris, D.V.5
Tsukamoto, T.6
-
98
-
-
34347402459
-
Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells
-
Yuneva, M., Zamboni, N., Oefner, P., Sachidanandam, R., and Lazebnik, Y. (2007). Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells. J. Cell Biol. 178, 93-105. doi: 10.1083/jcb.200703099
-
(2007)
J. Cell Biol
, vol.178
, pp. 93-105
-
-
Yuneva, M.1
Zamboni, N.2
Oefner, P.3
Sachidanandam, R.4
Lazebnik, Y.5
-
99
-
-
84879289434
-
MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells
-
Zirath, H., Frenzel, A., Oliynyk, G., Segerström, L., Westermark, U. K., Larsson, K., et al. (2013). MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells. Proc. Natl. Acad. Sci. U.S.A. 110, 10258-10263. doi: 10.1073/pnas.1222404110
-
(2013)
Proc. Natl. Acad. Sci. U.S.A
, vol.110
, pp. 10258-10263
-
-
Zirath, H.1
Frenzel, A.2
Oliynyk, G.3
Segerström, L.4
Westermark, U.K.5
Larsson, K.6
|