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Volumn 14, Issue 9, 2016, Pages 2154-2165

Fatty Acid Oxidation-Driven Src Links Mitochondrial Energy Reprogramming and Oncogenic Properties in Triple-Negative Breast Cancer

(25)  Park, Jun Hyoung a   Vithayathil, Sajna a   Kumar, Santosh a   Sung, Pi Lin a,b   Dobrolecki, Lacey Elizabeth a   Putluri, Vasanta a   Bhat, Vadiraja B c   Bhowmik, Salil Kumar a   Gupta, Vineet a   Arora, Kavisha a   Wu, Danli d   Tsouko, Efrosini e   Zhang, Yiqun a   Maity, Suman a   Donti, Taraka R a   Graham, Brett H a   Frigo, Daniel E e,f   Coarfa, Cristian a   Yotnda, Patricia d   Putluri, Nagireddy a   more..


Author keywords

[No Author keywords available]

Indexed keywords

CARNITINE PALMITOYLTRANSFERASE; CARNITINE PALMITOYLTRANSFERASE 1A; CARNITINE PALMITOYLTRANSFERASE 2; MITOCHONDRIAL DNA; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG; FATTY ACID;

EID: 84960423377     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.02.004     Document Type: Article
Times cited : (224)

References (66)
  • 1
    • 77953567491 scopus 로고    scopus 로고
    • Modulation of mitochondrial protein phosphorylation by soluble adenylyl cyclase ameliorates cytochrome oxidase defects
    • Acín-Perez R., Salazar E., Brosel S., Yang H., Schon E.A., Manfredi G. Modulation of mitochondrial protein phosphorylation by soluble adenylyl cyclase ameliorates cytochrome oxidase defects. EMBO Mol. Med. 2009, 1:392-406.
    • (2009) EMBO Mol. Med. , vol.1 , pp. 392-406
    • Acín-Perez, R.1    Salazar, E.2    Brosel, S.3    Yang, H.4    Schon, E.A.5    Manfredi, G.6
  • 3
    • 77956042544 scopus 로고    scopus 로고
    • SRC: a century of science brought to the clinic
    • Aleshin A., Finn R.S. SRC: a century of science brought to the clinic. Neoplasia 2010, 12:599-607.
    • (2010) Neoplasia , vol.12 , pp. 599-607
    • Aleshin, A.1    Finn, R.S.2
  • 4
    • 84858741454 scopus 로고    scopus 로고
    • Subcellular localization of total and activated Src kinase in African American and Caucasian breast cancer
    • Anbalagan M., Moroz K., Ali A., Carrier L., Glodowski S., Rowan B.G. Subcellular localization of total and activated Src kinase in African American and Caucasian breast cancer. PLoS ONE 2012, 7:e33017.
    • (2012) PLoS ONE , vol.7 , pp. e33017
    • Anbalagan, M.1    Moroz, K.2    Ali, A.3    Carrier, L.4    Glodowski, S.5    Rowan, B.G.6
  • 5
    • 84926432140 scopus 로고    scopus 로고
    • Obesity and cancer progression: is there a role of fatty acid metabolism?
    • Balaban S., Lee L.S., Schreuder M., Hoy A.J. Obesity and cancer progression: is there a role of fatty acid metabolism?. BioMed Res. Int. 2015, 2015:274585.
    • (2015) BioMed Res. Int. , vol.2015 , pp. 274585
    • Balaban, S.1    Lee, L.S.2    Schreuder, M.3    Hoy, A.J.4
  • 6
    • 84922373212 scopus 로고    scopus 로고
    • Mitochondrial dependency in progression of acute myeloid leukemia
    • Basak N.P., Banerjee S. Mitochondrial dependency in progression of acute myeloid leukemia. Mitochondrion 2015, 21:41-48.
    • (2015) Mitochondrion , vol.21 , pp. 41-48
    • Basak, N.P.1    Banerjee, S.2
  • 7
    • 84868000180 scopus 로고    scopus 로고
    • Non-glucose metabolism in cancer cells--is it all in the fat?
    • Biswas S., Lunec J., Bartlett K. Non-glucose metabolism in cancer cells--is it all in the fat?. Cancer Metastasis Rev. 2012, 31:689-698.
    • (2012) Cancer Metastasis Rev. , vol.31 , pp. 689-698
    • Biswas, S.1    Lunec, J.2    Bartlett, K.3
  • 9
    • 84868019043 scopus 로고    scopus 로고
    • Cancer cell metabolism: one hallmark, many faces
    • Cantor J.R., Sabatini D.M. Cancer cell metabolism: one hallmark, many faces. Cancer Discov. 2012, 2:881-898.
    • (2012) Cancer Discov. , vol.2 , pp. 881-898
    • Cantor, J.R.1    Sabatini, D.M.2
  • 10
    • 84875465199 scopus 로고    scopus 로고
    • Cancer metabolism: fatty acid oxidation in the limelight
    • Carracedo A., Cantley L.C., Pandolfi P.P. Cancer metabolism: fatty acid oxidation in the limelight. Nat. Rev. Cancer 2013, 13:227-232.
    • (2013) Nat. Rev. Cancer , vol.13 , pp. 227-232
    • Carracedo, A.1    Cantley, L.C.2    Pandolfi, P.P.3
  • 11
    • 85019795469 scopus 로고    scopus 로고
    • Abstract S5-08: Final survival analysis from the randomized Women's Intervention Nutrition Study (WINS) evaluating dietary intervention as adjuvant breast cancer therapy
    • Chlebowski R.T., Blackburn G.L. Abstract S5-08: Final survival analysis from the randomized Women's Intervention Nutrition Study (WINS) evaluating dietary intervention as adjuvant breast cancer therapy. Cancer Res. 2015, 75:S5-S08.
    • (2015) Cancer Res. , vol.75 , pp. S5-S08
    • Chlebowski, R.T.1    Blackburn, G.L.2
  • 12
    • 84865510296 scopus 로고    scopus 로고
    • Targeting malignant mitochondria with therapeutic peptides
    • Constance J.E., Lim C.S. Targeting malignant mitochondria with therapeutic peptides. Ther. Deliv. 2012, 3:961-979.
    • (2012) Ther. Deliv. , vol.3 , pp. 961-979
    • Constance, J.E.1    Lim, C.S.2
  • 14
    • 46349084468 scopus 로고    scopus 로고
    • Multiple oncogenic pathway signatures show coordinate expression patterns in human prostate tumors
    • Creighton C.J. Multiple oncogenic pathway signatures show coordinate expression patterns in human prostate tumors. PLoS ONE 2008, 3:e1816.
    • (2008) PLoS ONE , vol.3 , pp. e1816
    • Creighton, C.J.1
  • 15
    • 21844479862 scopus 로고    scopus 로고
    • Retrograde regulation due to mitochondrial dysfunction may be an important mechanism for carcinogenesis
    • Erol A. Retrograde regulation due to mitochondrial dysfunction may be an important mechanism for carcinogenesis. Med. Hypotheses 2005, 65:525-529.
    • (2005) Med. Hypotheses , vol.65 , pp. 525-529
    • Erol, A.1
  • 16
    • 48749118203 scopus 로고    scopus 로고
    • Targeting Src in breast cancer
    • Finn R.S. Targeting Src in breast cancer. Ann. Oncol. 2008, 19:1379-1386.
    • (2008) Ann. Oncol. , vol.19 , pp. 1379-1386
    • Finn, R.S.1
  • 20
    • 23944478449 scopus 로고    scopus 로고
    • Mitochondria: A novel target for the chemoprevention of cancer
    • Hail N. Mitochondria: A novel target for the chemoprevention of cancer. Apoptosis 2005, 10:687-705.
    • (2005) Apoptosis , vol.10 , pp. 687-705
    • Hail, N.1
  • 21
    • 84951796601 scopus 로고    scopus 로고
    • Targeting fatty acid metabolism in cancer and endothelial cells
    • Harjes U., Kalucka J., Carmeliet P. Targeting fatty acid metabolism in cancer and endothelial cells. Crit. Rev. Oncol. Hematol. 2016, 97:15-21.
    • (2016) Crit. Rev. Oncol. Hematol. , vol.97 , pp. 15-21
    • Harjes, U.1    Kalucka, J.2    Carmeliet, P.3
  • 22
    • 84870695545 scopus 로고    scopus 로고
    • Src kinases are important regulators of mitochondrial functions
    • Hebert-Chatelain E. Src kinases are important regulators of mitochondrial functions. Int. J. Biochem. Cell Biol. 2013, 45:90-98.
    • (2013) Int. J. Biochem. Cell Biol. , vol.45 , pp. 90-98
    • Hebert-Chatelain, E.1
  • 26
    • 77955299384 scopus 로고    scopus 로고
    • Functional effects of cancer mitochondria on energy metabolism and tumorigenesis: utility of transmitochondrial cybrids
    • Kaipparettu B.A., Ma Y., Wong L.J. Functional effects of cancer mitochondria on energy metabolism and tumorigenesis: utility of transmitochondrial cybrids. Ann. N Y Acad. Sci. 2010, 1201:137-146.
    • (2010) Ann. N Y Acad. Sci. , vol.1201 , pp. 137-146
    • Kaipparettu, B.A.1    Ma, Y.2    Wong, L.J.3
  • 27
    • 84877317238 scopus 로고    scopus 로고
    • Crosstalk from non-cancerous mitochondria can inhibit tumor properties of metastatic cells by suppressing oncogenic pathways
    • Kaipparettu B.A., Ma Y., Park J.H., Lee T.L., Zhang Y., Yotnda P., Creighton C.J., Chan W.Y., Wong L.J. Crosstalk from non-cancerous mitochondria can inhibit tumor properties of metastatic cells by suppressing oncogenic pathways. PLoS ONE 2013, 8:e61747.
    • (2013) PLoS ONE , vol.8 , pp. e61747
    • Kaipparettu, B.A.1    Ma, Y.2    Park, J.H.3    Lee, T.L.4    Zhang, Y.5    Yotnda, P.6    Creighton, C.J.7    Chan, W.Y.8    Wong, L.J.9
  • 29
    • 0024448458 scopus 로고
    • Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation
    • King M.P., Attardi G. Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation. Science 1989, 246:500-503.
    • (1989) Science , vol.246 , pp. 500-503
    • King, M.P.1    Attardi, G.2
  • 31
    • 84862817269 scopus 로고    scopus 로고
    • Effects of L-carnitine against oxidative stress in human hepatocytes: involvement of peroxisome proliferator-activated receptor alpha
    • Li J.L., Wang Q.Y., Luan H.Y., Kang Z.C., Wang C.B. Effects of L-carnitine against oxidative stress in human hepatocytes: involvement of peroxisome proliferator-activated receptor alpha. J. Biomed. Sci. 2012, 19:32.
    • (2012) J. Biomed. Sci. , vol.19 , pp. 32
    • Li, J.L.1    Wang, Q.Y.2    Luan, H.Y.3    Kang, Z.C.4    Wang, C.B.5
  • 32
    • 84924530354 scopus 로고    scopus 로고
    • ErbB2 pathway activation upon smad4 loss promotes lung tumor growth and metastasis
    • S2211-1247(15)00142-4
    • Liu J., Cho S.N., Akkanti B., Jin N., Mao J., Long W., Chen T., Zhang Y., Tang X., Wistub I.I., et al. ErbB2 pathway activation upon smad4 loss promotes lung tumor growth and metastasis. Cell Rep. 2015, S2211-1247(15)00142-4. 10.1016/j.celrep.2015.02.014.
    • (2015) Cell Rep.
    • Liu, J.1    Cho, S.N.2    Akkanti, B.3    Jin, N.4    Mao, J.5    Long, W.6    Chen, T.7    Zhang, Y.8    Tang, X.9    Wistub, I.I.10
  • 33
    • 33745106287 scopus 로고    scopus 로고
    • Molecular links between obesity and breast cancer
    • Lorincz A.M., Sukumar S. Molecular links between obesity and breast cancer. Endocr. Relat. Cancer 2006, 13:279-292.
    • (2006) Endocr. Relat. Cancer , vol.13 , pp. 279-292
    • Lorincz, A.M.1    Sukumar, S.2
  • 34
    • 84961288714 scopus 로고    scopus 로고
    • Tumor cells switch to mitochondrial oxidative phosphorylation under radiation via mTOR-mediated hexokinase II inhibition--a Warburg-reversing effect
    • Lu C.L., Qin L., Liu H.C., Candas D., Fan M., Li J.J. Tumor cells switch to mitochondrial oxidative phosphorylation under radiation via mTOR-mediated hexokinase II inhibition--a Warburg-reversing effect. PLoS ONE 2015, 10:e0121046.
    • (2015) PLoS ONE , vol.10 , pp. e0121046
    • Lu, C.L.1    Qin, L.2    Liu, H.C.3    Candas, D.4    Fan, M.5    Li, J.J.6
  • 35
    • 84920563297 scopus 로고    scopus 로고
    • Essential role for oxidative phosphorylation in cancer progression
    • Maiuri M.C., Kroemer G. Essential role for oxidative phosphorylation in cancer progression. Cell Metab. 2015, 21:11-12.
    • (2015) Cell Metab. , vol.21 , pp. 11-12
    • Maiuri, M.C.1    Kroemer, G.2
  • 36
    • 77954690732 scopus 로고    scopus 로고
    • Advances in targeting SRC in the treatment of breast cancer and other solid malignancies
    • Mayer E.L., Krop I.E. Advances in targeting SRC in the treatment of breast cancer and other solid malignancies. Clin. Cancer Res. 2010, 16:3526-3532.
    • (2010) Clin. Cancer Res. , vol.16 , pp. 3526-3532
    • Mayer, E.L.1    Krop, I.E.2
  • 38
    • 0037416134 scopus 로고    scopus 로고
    • Regulation of cytochrome c oxidase activity by c-Src in osteoclasts
    • Miyazaki T., Neff L., Tanaka S., Horne W.C., Baron R. Regulation of cytochrome c oxidase activity by c-Src in osteoclasts. J. Cell Biol. 2003, 160:709-718.
    • (2003) J. Cell Biol. , vol.160 , pp. 709-718
    • Miyazaki, T.1    Neff, L.2    Tanaka, S.3    Horne, W.C.4    Baron, R.5
  • 39
    • 84883814194 scopus 로고    scopus 로고
    • Classification of mitocans, anti-cancer drugs acting on mitochondria
    • Neuzil J., Dong L.F., Rohlena J., Truksa J., Ralph S.J. Classification of mitocans, anti-cancer drugs acting on mitochondria. Mitochondrion 2013, 13:199-208.
    • (2013) Mitochondrion , vol.13 , pp. 199-208
    • Neuzil, J.1    Dong, L.F.2    Rohlena, J.3    Truksa, J.4    Ralph, S.J.5
  • 41
    • 81955165133 scopus 로고    scopus 로고
    • Mitochondrial protein phosphorylation as a regulatory modality: implications for mitochondrial dysfunction in heart failure
    • O'Rourke B., Van Eyk J.E., Foster D.B. Mitochondrial protein phosphorylation as a regulatory modality: implications for mitochondrial dysfunction in heart failure. Congest. Heart Fail. 2011, 17:269-282.
    • (2011) Congest. Heart Fail. , vol.17 , pp. 269-282
    • O'Rourke, B.1    Van Eyk, J.E.2    Foster, D.B.3
  • 42
    • 84866880855 scopus 로고    scopus 로고
    • Mitochondrial c-Src regulates cell survival through phosphorylation of respiratory chain components
    • Ogura M., Yamaki J., Homma M.K., Homma Y. Mitochondrial c-Src regulates cell survival through phosphorylation of respiratory chain components. Biochem. J. 2012, 447:281-289.
    • (2012) Biochem. J. , vol.447 , pp. 281-289
    • Ogura, M.1    Yamaki, J.2    Homma, M.K.3    Homma, Y.4
  • 43
    • 84907821817 scopus 로고    scopus 로고
    • Phosphorylation of flotillin-1 by mitochondrial c-Src is required to prevent the production of reactive oxygen species
    • Ogura M., Yamaki J., Homma M.K., Homma Y. Phosphorylation of flotillin-1 by mitochondrial c-Src is required to prevent the production of reactive oxygen species. FEBS Lett. 2014, 588:2837-2843.
    • (2014) FEBS Lett. , vol.588 , pp. 2837-2843
    • Ogura, M.1    Yamaki, J.2    Homma, M.K.3    Homma, Y.4
  • 44
    • 84867853849 scopus 로고    scopus 로고
    • Mitochondrial defect drives non-autonomous tumour progression through Hippo signalling in Drosophila
    • Ohsawa S., Sato Y., Enomoto M., Nakamura M., Betsumiya A., Igaki T. Mitochondrial defect drives non-autonomous tumour progression through Hippo signalling in Drosophila. Nature 2012, 490:547-551.
    • (2012) Nature , vol.490 , pp. 547-551
    • Ohsawa, S.1    Sato, Y.2    Enomoto, M.3    Nakamura, M.4    Betsumiya, A.5    Igaki, T.6
  • 45
    • 84943767095 scopus 로고    scopus 로고
    • MicroRNAs as the fine-tuners of Src oncogenic signalling
    • Oneyama C., Okada M. MicroRNAs as the fine-tuners of Src oncogenic signalling. J. Biochem. 2015, 157:431-438.
    • (2015) J. Biochem. , vol.157 , pp. 431-438
    • Oneyama, C.1    Okada, M.2
  • 46
    • 68149100794 scopus 로고    scopus 로고
    • Triple-negative breast cancer: novel therapies and new directions
    • Pal S.K., Mortimer J. Triple-negative breast cancer: novel therapies and new directions. Maturitas 2009, 63:269-274.
    • (2009) Maturitas , vol.63 , pp. 269-274
    • Pal, S.K.1    Mortimer, J.2
  • 47
    • 84871783047 scopus 로고    scopus 로고
    • Obesity as a risk factor for triple-negative breast cancers: a systematic review and meta-analysis
    • Pierobon M., Frankenfeld C.L. Obesity as a risk factor for triple-negative breast cancers: a systematic review and meta-analysis. Breast Cancer Res. Treat. 2013, 137:307-314.
    • (2013) Breast Cancer Res. Treat. , vol.137 , pp. 307-314
    • Pierobon, M.1    Frankenfeld, C.L.2
  • 48
    • 84887615195 scopus 로고    scopus 로고
    • L-carnitine supplementation as a potential antioxidant therapy for inherited neurometabolic disorders
    • Ribas G.S., Vargas C.R., Wajner M. L-carnitine supplementation as a potential antioxidant therapy for inherited neurometabolic disorders. Gene 2014, 533:469-476.
    • (2014) Gene , vol.533 , pp. 469-476
    • Ribas, G.S.1    Vargas, C.R.2    Wajner, M.3
  • 49
    • 75949102926 scopus 로고    scopus 로고
    • Biological mechanisms linking obesity and cancer risk: new perspectives
    • Roberts D.L., Dive C., Renehan A.G. Biological mechanisms linking obesity and cancer risk: new perspectives. Annu. Rev. Med. 2010, 61:301-316.
    • (2010) Annu. Rev. Med. , vol.61 , pp. 301-316
    • Roberts, D.L.1    Dive, C.2    Renehan, A.G.3
  • 50
    • 84923102615 scopus 로고    scopus 로고
    • Src protein-tyrosine kinase structure, mechanism, and small molecule inhibitors
    • Roskoski R. Src protein-tyrosine kinase structure, mechanism, and small molecule inhibitors. Pharmacol. Res. 2015, 94:9-25.
    • (2015) Pharmacol. Res. , vol.94 , pp. 9-25
    • Roskoski, R.1
  • 51
    • 0037012576 scopus 로고    scopus 로고
    • Characterization and location of Src-dependent tyrosine phosphorylation in rat brain mitochondria
    • Salvi M., Brunati A.M., Bordin L., La Rocca N., Clari G., Toninello A. Characterization and location of Src-dependent tyrosine phosphorylation in rat brain mitochondria. Biochim. Biophys. Acta 2002, 1589:181-195.
    • (2002) Biochim. Biophys. Acta , vol.1589 , pp. 181-195
    • Salvi, M.1    Brunati, A.M.2    Bordin, L.3    La Rocca, N.4    Clari, G.5    Toninello, A.6
  • 53
    • 84888377791 scopus 로고    scopus 로고
    • Metabolomics reveals that carnitine palmitoyltransferase-1 is a novel target for oxidative inactivation in human cells
    • Setoyama D., Fujimura Y., Miura D. Metabolomics reveals that carnitine palmitoyltransferase-1 is a novel target for oxidative inactivation in human cells. Genes Cells 2013, 18:1107-1119.
    • (2013) Genes Cells , vol.18 , pp. 1107-1119
    • Setoyama, D.1    Fujimura, Y.2    Miura, D.3
  • 54
    • 84921293145 scopus 로고    scopus 로고
    • Contribution of phosphoproteomics in understanding SRC signaling in normal and tumor cells
    • Sirvent A., Urbach S., Roche S. Contribution of phosphoproteomics in understanding SRC signaling in normal and tumor cells. Proteomics 2015, 15:232-244.
    • (2015) Proteomics , vol.15 , pp. 232-244
    • Sirvent, A.1    Urbach, S.2    Roche, S.3
  • 59
    • 84937779724 scopus 로고    scopus 로고
    • Lymphocyte-specific protein tyrosine kinase (Lck) interacts with CR6-interacting factor 1 (CRIF1) in mitochondria to repress oxidative phosphorylation
    • Vahedi S., Chueh F.Y., Chandran B., Yu C.L. Lymphocyte-specific protein tyrosine kinase (Lck) interacts with CR6-interacting factor 1 (CRIF1) in mitochondria to repress oxidative phosphorylation. BMC Cancer 2015, 15:551.
    • (2015) BMC Cancer , vol.15 , pp. 551
    • Vahedi, S.1    Chueh, F.Y.2    Chandran, B.3    Yu, C.L.4
  • 60
    • 84942872148 scopus 로고    scopus 로고
    • Tumors and mitochondrial respiration: a neglected connection
    • Viale A., Corti D., Draetta G.F. Tumors and mitochondrial respiration: a neglected connection. Cancer Res. 2015, 75:3685-3686.
    • (2015) Cancer Res. , vol.75 , pp. 3685-3686
    • Viale, A.1    Corti, D.2    Draetta, G.F.3
  • 61
    • 84923070289 scopus 로고    scopus 로고
    • Metabolism: the mitochondria thief
    • Villanueva M.T. Metabolism: the mitochondria thief. Nat. Rev. Cancer 2015, 15:70-71.
    • (2015) Nat. Rev. Cancer , vol.15 , pp. 70-71
    • Villanueva, M.T.1
  • 62
    • 84863011496 scopus 로고    scopus 로고
    • Transmitochondrial cybrids: tools for functional studies of mutant mitochondria
    • Vithayathil S.A., Ma Y., Kaipparettu B.A. Transmitochondrial cybrids: tools for functional studies of mutant mitochondria. Methods Mol. Biol. 2012, 837:219-230.
    • (2012) Methods Mol. Biol. , vol.837 , pp. 219-230
    • Vithayathil, S.A.1    Ma, Y.2    Kaipparettu, B.A.3
  • 63
    • 84858604270 scopus 로고    scopus 로고
    • Metabolic reprogramming: a cancer hallmark even warburg did not anticipate
    • Ward P.S., Thompson C.B. Metabolic reprogramming: a cancer hallmark even warburg did not anticipate. Cancer Cell 2012, 21:297-308.
    • (2012) Cancer Cell , vol.21 , pp. 297-308
    • Ward, P.S.1    Thompson, C.B.2
  • 64
    • 84925486756 scopus 로고    scopus 로고
    • Targeting metabolic plasticity in breast cancer cells via mitochondrial complex I modulation
    • Xu Q., Biener-Ramanujan E., Yang W., Ramanujan V.K. Targeting metabolic plasticity in breast cancer cells via mitochondrial complex I modulation. Breast Cancer Res. Treat. 2015, 150:43-56.
    • (2015) Breast Cancer Res. Treat. , vol.150 , pp. 43-56
    • Xu, Q.1    Biener-Ramanujan, E.2    Yang, W.3    Ramanujan, V.K.4
  • 65
    • 84857916018 scopus 로고    scopus 로고
    • Targeting Src family kinases in anti-cancer therapies: turning promise into triumph
    • Zhang S., Yu D. Targeting Src family kinases in anti-cancer therapies: turning promise into triumph. Trends Pharmacol. Sci. 2012, 33:122-128.
    • (2012) Trends Pharmacol. Sci. , vol.33 , pp. 122-128
    • Zhang, S.1    Yu, D.2
  • 66
    • 84881415504 scopus 로고    scopus 로고
    • A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models
    • Zhang X., Claerhout S., Prat A., Dobrolecki L.E., Petrovic I., Lai Q., Landis M.D., Wiechmann L., Schiff R., Giuliano M., et al. A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models. Cancer Res. 2013, 73:4885-4897.
    • (2013) Cancer Res. , vol.73 , pp. 4885-4897
    • Zhang, X.1    Claerhout, S.2    Prat, A.3    Dobrolecki, L.E.4    Petrovic, I.5    Lai, Q.6    Landis, M.D.7    Wiechmann, L.8    Schiff, R.9    Giuliano, M.10


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