Association of FABP5 expression with poor survival in triple-negative breast cancer: Implication for retinoic acid therapy

American Journal of Pathology

Volumn 178, Issue 3, 2011, Pages 997-1008

  Liu, Rong Zong ^a   Graham, Kathryn ^a   Glubrecht, Darryl D ^a   Germain, Devon R ^a   Mackey, John R ^a   Godbout, Roseline ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CYTOPLASM PROTEIN; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR; PROTEIN FABP5; RETINOIC ACID; RNA; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER GRADING; CANCER INHIBITION; CELL GROWTH; CONTROLLED STUDY; CYTOPLASM; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; TISSUE MICROARRAY;

EID: 79952772664     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2010.11.075     Document Type: Article

References (51)

1. Dolled-Filhart M, Rydén L, Cregger M, JirströM K, Harigopal M, Camp RL, Rimm DL: Classification of breast cancer using genetic algorithms and tissue microarrays. Clin Cancer Res 2006, 12:6459-6468 (Pubitemid 44799719)
2. Liu R, Wang X, Chen GY, Dalerba P, Gurney A, Hoey T, Sherlock G, Lewicki J, Shedden K, Clarke MF: The prognostic role of a gene signature from tumorigenic breast-cancer cells. N Engl J Med 2007, 356:217-226 (Pubitemid 46143225)
3. Pohlmann PR, Mayer IA, Mernaugh R: Resistance to trastuzumab in breast cancer. Clin Cancer Res 2009, 15:7479-7491
4. Tan AR, Swain SM: Therapeutic strategies for triple-negative breast cancer. Cancer J 2008;14:343-351
5. Bonanni B, Lazzeroni M: Retinoids and breast cancer prevention. Recent Results Cancer Res 2009, 181:77-82
6. Zanardi S, Serrano D, Argusti A, Barile M, Puntoni M, Decensi A: Clinical trials with retinoids for breast cancer chemoprevention. Endocr Relat Cancer 2006, 13:51-68
7. Calviello G, Serini S, Piccioni E, Pessina G: Antineoplastic effects of n-3 polyunsaturated fatty acids in combination with drugs and radiotherapy: preventive and therapeutic strategies. Nutr Cancer 2009, 61:287-301
8. Shen Q, Brown PH: Novel agents for the prevention of breast cancer: targeting transcription factors and signal transduction pathways. J Mammary Gland Biol Neoplasia 2003, 8:45-73 (Pubitemid 38129950)
9. Soprano KJ, Soprano DR: Retinoic acid receptors and cancer. J Nutr 2002, 132:3809S-3813S
10. Garattini E, Gianni M, Terao M: Retinoids as differentiating agents in oncology: a network of interactions with intracellular pathways as the basis for rational therapeutic combinations. Curr Pharm Des 2007, 13:1375-1400 (Pubitemid 46758854)
11. Schug TT, Berry DC, Shaw NS, Travis SN, Noy N: Opposing effects of retinoic acid on cell growth result from alternate activation of two different nuclear receptors. Cell 2007, 129:723-733 (Pubitemid 46802374)
12. Schug TT, Berry DC, Toshkov IA, Cheng L, Nikitin AY, Noy N: Overcoming retinoic acid-resistance of mammary carcinomas by diverting retinoic acid from PPARbeta/delta to RAR. Proc Natl Acad Sci U S A 2008, 105:7546-7551 (Pubitemid 351830055)
13. Cho Y, Tighe AP, Talmage DA: Retinoic acid induced growth arrest of human breast carcinoma cells requires protein kinase C alpha expression and activity. J Cell Physiol 1997, 172:306-313 (Pubitemid 27376196)
14. Lotan R: Retinoids in cancer chemoprevention. FASEB J 1996, 10:1031-1039
15. Li Y, Brown PH: Prevention of ER-negative breast cancer. Recent Results Cancer Res 2009, 181:121-134
16. Conzen SD: Minireview: nuclear receptors and breast cancer. Mol Endocrinol 2008, 22:2215-2228
17. Schroeder F, Petrescu AD, Huang H, Atshaves BP, McIntosh AL, Martin GG, Hostetler HA, Vespa A, Landrock D, Landrock KK, Payne HR, Kier AB: Role of fatty acid binding proteins and long chain fatty acids in modulating nuclear receptors and gene transcription. Lipids 2008, 43:1-17 (Pubitemid 351206956)
18. Liu RZ, Li X, Godbout R: A novel fatty acid-binding protein (FABP) gene resulting from tandem gene duplication in mammals: transcription in rat retina and testis. Genomics 2008, 92:436-445
19. Schaap FG, van der Vusse GJ, Glatz JF: Evolution of the family of intracellular lipid binding proteins in vertebrates. Mol Cell Biochem 2002, 239:69-77 (Pubitemid 35385797)
20. Donato LJ, Noy N: Suppression of mammary carcinoma growth by retinoic acid: proapoptotic genes are targets for retinoic acid receptor and cellular retinoic acid-binding protein II signaling. Cancer Res 2005, 65:8193-8199 (Pubitemid 41334794)
21. Storch J, Corsico B: The emerging functions and mechanisms of mammalian fatty acid-binding proteins. Annu Rev Nutr 2008, 28:73-95
22. Hancke K, Grubeck D, Hauser N, Kreienberg R, Weiss JM: Adipocyte fatty acid-binding protein as a novel prognostic factor in obese breast cancer patients. Breast Cancer Res Treat 2010, 119:367-367
23. Zhang H, Rakha EA, Ball GR, Spiteri I, Aleskandarany M, Paish EC, Powe DG, Macmillan RD, Caldas C, Ellis IO, Green AR: The proteins FABP7 and OATP2 are associated with the basal phenotype and patient outcome in human breast cancer. Breast Cancer Res Treat 2010, 121:41-51
24. Germain DR, Graham K, Glubrecht DD, Hugh JC, Mackey JR, Godbout R: DEAD box 1: a novel and independent prognostic marker for early recurrence in breast cancer. Breast Cancer Res Treat 2010. DOI: 10.1007/s10549-010-0943-7
25. Edgar R, Domrachev M, Lash AE: Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res 2002, 30:207-210 (Pubitemid 34679544)
26. Neve RM, Chin K, Fridlyand J, Yeh J, Baehner FL, Fevr T, Clark L, Bayani N, Coppe JP, Tong F, Speed T, Spellman PT, DeVries S, Lapuk A, Wang NJ, Kuo WL, Stilwell JL, Pinkel D, Albertson DG, Waldman FM, McCormick F, Dickson RB, Johnson MD, Lippman M, Ethier S, Gazdar A, Gray JW: A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 2006, 10:515-527 (Pubitemid 44854747)
27. She QB, Chandarlapaty S, Ye Q, Lobo J, Haskell KM, Leander KR, DeFeo-Jones D, Huber HE, Rosen N: Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling. PLoS One 2008, 3:e3065
28. Richardson AL, Wang ZC, De Nicolo A, Lu X, Brown M, Miron A, Liao X, Iglehart JD, Livingston DM, Ganesan S: X chromosomal abnormalities in basal-like human breast cancer. Cancer Cell 2006, 9:121-132 (Pubitemid 43202662)
29. Farmer P, Bonnefoi H, Becette V, Tubiana-Hulin M, Fumoleau P, Larsimont D, Macgrogan G, Bergh J, Cameron D, Goldstein D, Duss S, Nicoulaz AL, Brisken C, Fiche M, Delorenzi M, Iggo R: Identification of molecular apocrine breast tumours by microarray analysis. Oncogene 2005, 24:4660-4671 (Pubitemid 41032603)
30. Györffy B, Lanczky A, Eklund AC, Denkert C, Budczies J, Li Q, Szallasi Z: An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients. Breast Cancer Res Treat 2010, 123:725-731
31. Madsen P, Rasmussen HH, Leffers H, Honoré B, Celis JE: Molecular cloning and expression of a novel keratinocyte protein (psoriasis-associated fatty acid-binding protein [PA-FABP]) that is highly upregulated in psoriatic skin and that shares similarity to fatty acid-binding proteins. J Invest Dermatol 1992, 99:299-305
32. Haunerland NH, Spener F: Fatty acid-binding proteins - insights from genetic manipulations. Prog Lipid Res 2004, 43:328-349 (Pubitemid 38952618)
33. Siegenthaler G, Hotz R, Chatellard-Gruaz D, Didierjean L, Hellman U, Saurat JH: Purification and characterization of the human epidermal fatty acid-binding protein: localization during epidermal cell differentiation in vivo and in vitro. Biochem J 1994, 302:363-371 (Pubitemid 24280086)
34. Adamson J, Morgan EA, Beesley C, Mei Y, Foster CS, Fujii H, Rudland PS, Smith PH, Ke Y: High-level expression of cutaneous fatty acid-binding protein in prostatic carcinomas and its effect on tumorigenicity. Oncogene 2003, 22:2739-2749 (Pubitemid 36612036)
35. Jing C, Beesley C, Foster CS, Rudland PS, Fujii H, Ono T, Chen H, Smith PH, Ke Y: Identification of the messenger RNA for human cutaneous fatty acid-binding protein as a metastasis inducer. Cancer Res 2000, 60:2390-2398 (Pubitemid 30262428)
36. Jing C, Beesley C, Foster CS, Chen H, Rudland PS, West DC, Fujii H, Smith PH, Ke Y: Human cutaneous fatty acid-binding protein induces metastasis by up-regulating the expression of vascular endothelial growth factor gene in rat Rama 37 model cells. Cancer Res 2001, 61:4357-4364 (Pubitemid 32685759)
37. Munz M, Zeidler R, Gires O: The tumour-associated antigen EpCAM upregulates the fatty acid binding protein E-FABP. Cancer Lett 2005, 225:151-157 (Pubitemid 40732778)
38. Gastl G, Spizzo G, Obrist P, Dunser M, Mikuz G: Ep-CAM overexpression in breast cancer as a predictor of survival. Lancet 2000, 356:1981-1982
39. Spizzo G, Went P, Dirnhofer S, Obrist P, Simon R, Spichtin H, Maurer R, Metzger U, von Castelberg B, Bart R, Stopatschinskaya S, Köchli OR, Haas P, Mross F, Zuber M, Dietrich H, Bischoff S, Mirlacher M, Sauter G, Gastl G: High Ep-CAM expression is associated with poor prognosis in node-positive breast cancer. Breast Cancer Res Treat 2004, 86:207-213 (Pubitemid 39070963)
40. Coller HA, Grandori C, Tamayo P, Colbert T, Lander ES, Eisenman RN, Golub TR: Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion. Proc Natl Acad Sci U S A 2000, 97:3260-3265 (Pubitemid 30183289)
41. Münz M, Kieu C, Mack B, Schmitt B, Zeidler R, Gires O: The carcinoma-associated antigen EpCAM upregulates c-myc and induces cell proliferation. Oncogene 2004, 23:5748-5758 (Pubitemid 39093020)
42. Liao DJ, Dickson RB: c-Myc in breast cancer. Endocr Relat Cancer 2000, 7:143-164
43. Dong D, Ruuska SE, Levinthal DJ, Noy N: Distinct roles for cellular retinoic acid-binding proteins I and II in regulating signaling by retinoic acid. J Biol Chem 1999, 274:23695-23698
44. Sussman F, de Lera AR: Ligand recognition by RAR and RXR receptors: binding and selectivity. J Med Chem 2005, 48:6212-6219 (Pubitemid 41428976)
45. Tan NS, Shaw NS, Vinckenbosch N, Liu P, Yasmin R, Desvergne B, Wahli W, Noy N: Selective cooperation between fatty acid binding proteins and peroxisome proliferator-activated receptors in regulating transcription [Erratum appeared in Mol Cell Biol 2002;22:6318]. Mol Cell Biol 2002, 22:5114-5127
46. Ahn EH, Chang CC, Talmage DA: Loss of anti-proliferative effect of all-trans retinoic acid in advanced stage of breast carcinogenesis. Anticancer Res 2009, 29:2899-2904
47. Morgan EA, Forootan SS, Adamson J, Foster CS, Fujii H, Igarashi M, Beesley C, Smith PH, Ke Y: Expression of cutaneous fatty acidbinding protein (C-FABP) in prostate cancer: potential prognostic marker and target for tumourigenicity-suppression. Int J Oncol 2008, 32:767-775 (Pubitemid 351780587)
48. Forootan SS, Bao ZZ, Forootan FS, Kamalian L, Zhang Y, Bee A, Foster CS, Ke Y: Atelocollagen-delivered siRNA targeting the FABP5 gene as an experimental therapy for prostate cancer in mouse xenografts. Int J Oncol 2010, 36:69-76
49. Huynh HT, Larsson C, Narod S, Pollak M: Tumor suppressor activity of the gene encoding mammary-derived growth inhibitor. Cancer Res 1995, 55:2225-2231
50. Shi YE, Ni J, Xiao G, Liu YE, Fuchs A, Yu G, Su J, Cosgrove JM, Xing L, Zhang M, Li J, Aggarwal BB, Meager A, Gentz R: Antitumor activity of the novel human breast cancer growth inhibitor, mammary-derived growth inhibitor-related gene, MRG. Cancer Res 1997, 57:3084-3091 (Pubitemid 27351715)
51. Tang XY, Umemura S, Tsukamoto H, Kumaki N, Tokuda Y, Osamura RY: Overexpression of fatty acid binding protein-7 correlates with basal-like subtype of breast cancer. Pathol Res Pract 2010, 206:98-101