메뉴 건너뛰기




Volumn 42, Issue , 2017, Pages 194-202

Assessing glycolytic flux alterations resulting from genetic perturbations in E. coli using a biosensor

Author keywords

Biosensor; Cra; Escherichia coli; Genome wide screening; Glycolytic flux; Transcription factor

Indexed keywords

BIOSENSORS; BIOSYNTHESIS; TRANSCRIPTION; TRANSCRIPTION FACTORS; CARBON; GENES;

EID: 85024100516     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2017.07.002     Document Type: Article
Times cited : (18)

References (70)
  • 3
    • 84881512097 scopus 로고    scopus 로고
    • Metabolic engineering of Escherichia coli to minimize byproduct formate and improving succinate productivity through increasing NADH availability by heterologous expression of NAD(+)-dependent formate dehydrogenase
    • Balzer, G.J., Thaker, C., Bennett, G.N., San, K.Y., Metabolic engineering of Escherichia coli to minimize byproduct formate and improving succinate productivity through increasing NADH availability by heterologous expression of NAD(+)-dependent formate dehydrogenase. Metab. Eng. 20 (2013), 1–8.
    • (2013) Metab. Eng. , vol.20 , pp. 1-8
    • Balzer, G.J.1    Thaker, C.2    Bennett, G.N.3    San, K.Y.4
  • 4
    • 84861434998 scopus 로고    scopus 로고
    • A high-throughput approach to identify genomic variants of bacterial metabolite producers at the single-cell level
    • Binder, S., Schendzielorz, G., Stäbler, N., Krumbach, K., Hoffmann, K., Bott, M., Eggeling, L., A high-throughput approach to identify genomic variants of bacterial metabolite producers at the single-cell level. Genome Biol., 13, 2012, R40.
    • (2012) Genome Biol. , vol.13 , pp. R40
    • Binder, S.1    Schendzielorz, G.2    Stäbler, N.3    Krumbach, K.4    Hoffmann, K.5    Bott, M.6    Eggeling, L.7
  • 5
    • 84880200801 scopus 로고    scopus 로고
    • Recombineering in Corynebacterium glutamicum combined with optical nanosensors: a general strategy for fast producer strain generation
    • Binder, S., Siedler, S., Marienhagen, J., Bott, M., Eggeling, L., Recombineering in Corynebacterium glutamicum combined with optical nanosensors: a general strategy for fast producer strain generation. Nucleic Acids Res. 41 (2013), 6360–6369.
    • (2013) Nucleic Acids Res. , vol.41 , pp. 6360-6369
    • Binder, S.1    Siedler, S.2    Marienhagen, J.3    Bott, M.4    Eggeling, L.5
  • 6
    • 0030029512 scopus 로고    scopus 로고
    • FruR mediates catabolite activation of pyruvate kinase (pykF) gene expression in Escherichia coli
    • Bledig, S.A., Ramseier, T.M., Saier, M.H., FruR mediates catabolite activation of pyruvate kinase (pykF) gene expression in Escherichia coli. J. Bacteriol. 178 (1996), 280–283.
    • (1996) J. Bacteriol. , vol.178 , pp. 280-283
    • Bledig, S.A.1    Ramseier, T.M.2    Saier, M.H.3
  • 9
    • 84978767428 scopus 로고    scopus 로고
    • Broad-host-range ProUSER vectors enable fast characterization of inducible promoters and optimization of p-coumaric acid production in Pseudomonas putida KT2440
    • Calero, P., Jensen, S.I., Nielsen, A.T., Broad-host-range ProUSER vectors enable fast characterization of inducible promoters and optimization of p-coumaric acid production in Pseudomonas putida KT2440. ACS Synth. Biol. 5 (2016), 741–753.
    • (2016) ACS Synth. Biol. , vol.5 , pp. 741-753
    • Calero, P.1    Jensen, S.I.2    Nielsen, A.T.3
  • 10
    • 84905974513 scopus 로고    scopus 로고
    • Variation in the fitness effects of mutations with population density and size in Escherichia coli
    • Cao, H., Butler, K., Hossain, M., Lewis, J.D., Variation in the fitness effects of mutations with population density and size in Escherichia coli. PLoS One, 9, 2014, e105369.
    • (2014) PLoS One , vol.9 , pp. e105369
    • Cao, H.1    Butler, K.2    Hossain, M.3    Lewis, J.D.4
  • 11
    • 84942045165 scopus 로고    scopus 로고
    • Accurate DNA assembly and genome engineering with optimized uracil excision cloning
    • Cavaleiro, A.M., Kim, S.H., Seppälä, S., Nielsen, M.T., Nørholm, M.H.H., Accurate DNA assembly and genome engineering with optimized uracil excision cloning. ACS Synth. Biol. 4 (2015), 1042–1046.
    • (2015) ACS Synth. Biol. , vol.4 , pp. 1042-1046
    • Cavaleiro, A.M.1    Kim, S.H.2    Seppälä, S.3    Nielsen, M.T.4    Nørholm, M.H.H.5
  • 14
    • 0023750782 scopus 로고
    • Nucleotide sequence and expression of the aceK gene coding for isocitrate dehydrogenase kinase/phosphatase in Escherichia coli
    • Cortay, J.C., Bleicher, F., Rieul, C., Reeves, H.C., Cozzone, A.J., Nucleotide sequence and expression of the aceK gene coding for isocitrate dehydrogenase kinase/phosphatase in Escherichia coli. J. Bacteriol. 170 (1988), 89–97.
    • (1988) J. Bacteriol. , vol.170 , pp. 89-97
    • Cortay, J.C.1    Bleicher, F.2    Rieul, C.3    Reeves, H.C.4    Cozzone, A.J.5
  • 15
    • 84875515904 scopus 로고    scopus 로고
    • Transcription factor-based screens and synthetic selections for microbial small-molecule biosynthesis
    • Dietrich, J.A., Shis, D.L., Alikhani, A., Keasling, J.D., Transcription factor-based screens and synthetic selections for microbial small-molecule biosynthesis. ACS Synth. Biol. 2 (2013), 47–58.
    • (2013) ACS Synth. Biol. , vol.2 , pp. 47-58
    • Dietrich, J.A.1    Shis, D.L.2    Alikhani, A.3    Keasling, J.D.4
  • 16
    • 85010842085 scopus 로고    scopus 로고
    • Genomewide landscape of gene-metabolome associations in Escherichia coli
    • Fuhrer, T., Zampieri, M., Sévin, D., Sauer, U., Zamboni, N., Genomewide landscape of gene-metabolome associations in Escherichia coli. Mol. Syst. Biol., 13(1), 2017, 907.
    • (2017) Mol. Syst. Biol. , vol.13 , Issue.1 , pp. 907
    • Fuhrer, T.1    Zampieri, M.2    Sévin, D.3    Sauer, U.4    Zamboni, N.5
  • 18
    • 84899698094 scopus 로고    scopus 로고
    • Programming biological operating systems: genome design, assembly and activation
    • Gibson, D.G., Programming biological operating systems: genome design, assembly and activation. Nat. Methods 11 (2014), 521–526.
    • (2014) Nat. Methods , vol.11 , pp. 521-526
    • Gibson, D.G.1
  • 19
    • 84886302057 scopus 로고    scopus 로고
    • Causes and effects of N-terminal codon bias in bacterial genes
    • Goodman, D.B., Church, G.M., Kosuri, S., Causes and effects of N-terminal codon bias in bacterial genes. Sci. (80-.) 342 (2013), 475–479.
    • (2013) Sci. (80-.) , vol.342 , pp. 475-479
    • Goodman, D.B.1    Church, G.M.2    Kosuri, S.3
  • 20
    • 67349267351 scopus 로고    scopus 로고
    • A genetic analysis of in vivo selenate reduction by Salmonella enterica serovar Typhimurium LT2 and Escherichia coli K12
    • Guymer, D., Maillard, J., Sargent, F., A genetic analysis of in vivo selenate reduction by Salmonella enterica serovar Typhimurium LT2 and Escherichia coli K12. Arch. Microbiol. 191 (2009), 519–528.
    • (2009) Arch. Microbiol. , vol.191 , pp. 519-528
    • Guymer, D.1    Maillard, J.2    Sargent, F.3
  • 21
    • 79953317811 scopus 로고    scopus 로고
    • Large-scale 13C-flux analysis reveals distinct transcriptional control of respiratory and fermentative metabolism in Escherichia coli
    • Haverkorn van Rijsewijk, B.R.B., Nanchen, A., Nallet, S., Kleijn, R.J., Sauer, U., Large-scale 13C-flux analysis reveals distinct transcriptional control of respiratory and fermentative metabolism in Escherichia coli. Mol. Syst. Biol., 7, 2011, 477.
    • (2011) Mol. Syst. Biol. , vol.7 , pp. 477
    • Haverkorn van Rijsewijk, B.R.B.1    Nanchen, A.2    Nallet, S.3    Kleijn, R.J.4    Sauer, U.5
  • 22
    • 84885398805 scopus 로고    scopus 로고
    • High variation of fluorescence protein maturation times in closely related Escherichia coli strains
    • Hebisch, E., Knebel, J., Landsberg, J., Frey, E., Leisner, M., High variation of fluorescence protein maturation times in closely related Escherichia coli strains. PLoS One, 8, 2013, e75991.
    • (2013) PLoS One , vol.8 , pp. e75991
    • Hebisch, E.1    Knebel, J.2    Landsberg, J.3    Frey, E.4    Leisner, M.5
  • 23
    • 0019479046 scopus 로고
    • Selectivity of the Escherichia coli outer membrane porins ompC and ompF
    • Heller, K.B., Wilson, T.H., Selectivity of the Escherichia coli outer membrane porins ompC and ompF. FEBS Lett. 129 (1981), 253–255.
    • (1981) FEBS Lett. , vol.129 , pp. 253-255
    • Heller, K.B.1    Wilson, T.H.2
  • 25
    • 84874608929 scopus 로고    scopus 로고
    • RNA-guided editing of bacterial genomes using CRISPR-Cas systems
    • Jiang, W., Bikard, D., Cox, D., Zhang, F., Marraffini, L.A., RNA-guided editing of bacterial genomes using CRISPR-Cas systems. Nat. Biotechnol. 31 (2013), 233–239.
    • (2013) Nat. Biotechnol. , vol.31 , pp. 233-239
    • Jiang, W.1    Bikard, D.2    Cox, D.3    Zhang, F.4    Marraffini, L.A.5
  • 27
    • 0347761177 scopus 로고    scopus 로고
    • Comparative metabolic flux analysis of lysine-producing Corynebacterium glutamicum cultured on glucose or fructose
    • Kiefer, P., Heinzle, E., Zelder, O., Wittmann, C., Comparative metabolic flux analysis of lysine-producing Corynebacterium glutamicum cultured on glucose or fructose. Appl. Environ. Microbiol. 70 (2004), 229–239.
    • (2004) Appl. Environ. Microbiol. , vol.70 , pp. 229-239
    • Kiefer, P.1    Heinzle, E.2    Zelder, O.3    Wittmann, C.4
  • 28
    • 84866539049 scopus 로고    scopus 로고
    • RELATCH: relative optimality in metabolic networks explains robust metabolic and regulatory responses to perturbations
    • Kim, J., Reed, J.L., RELATCH: relative optimality in metabolic networks explains robust metabolic and regulatory responses to perturbations. Genome Biol., 13, 2012, R78.
    • (2012) Genome Biol. , vol.13 , pp. R78
    • Kim, J.1    Reed, J.L.2
  • 29
    • 72249097352 scopus 로고    scopus 로고
    • Growth rate-dependent global effects on gene expression in bacteria
    • Klumpp, S., Zhang, Z., Hwa, T., Growth rate-dependent global effects on gene expression in bacteria. Cell 139 (2009), 1366–1375.
    • (2009) Cell , vol.139 , pp. 1366-1375
    • Klumpp, S.1    Zhang, Z.2    Hwa, T.3
  • 31
    • 84899696363 scopus 로고    scopus 로고
    • Large-scale de novo DNA synthesis: technologies and applications
    • Kosuri, S., Church, G.M., Large-scale de novo DNA synthesis: technologies and applications. Nat. Methods 11 (2014), 499–507.
    • (2014) Nat. Methods , vol.11 , pp. 499-507
    • Kosuri, S.1    Church, G.M.2
  • 33
    • 0020355238 scopus 로고
    • A protein with kinase and phosphatase activities involved in regulation of tricarboxylic acid cycle
    • LaPorte, D.C., Koshland, D.E., A protein with kinase and phosphatase activities involved in regulation of tricarboxylic acid cycle. Nature 300 (1982), 458–460.
    • (1982) Nature , vol.300 , pp. 458-460
    • LaPorte, D.C.1    Koshland, D.E.2
  • 34
    • 84907020111 scopus 로고    scopus 로고
    • Combinatorial strategies for improving multiple-stress resistance in industrially relevant Escherichia coli strains
    • Lennen, R.M., Herrgård, M.J., Combinatorial strategies for improving multiple-stress resistance in industrially relevant Escherichia coli strains. Appl. Environ. Microbiol. 80 (2014), 6223–6242.
    • (2014) Appl. Environ. Microbiol. , vol.80 , pp. 6223-6242
    • Lennen, R.M.1    Herrgård, M.J.2
  • 35
    • 84861144335 scopus 로고    scopus 로고
    • Loss of outer membrane protein C in Escherichia coli contributes to both antibiotic resistance and escaping antibody-dependent bactericidal activity
    • Liu, Y.-F., Yan, J.-J., Lei, H.-Y., Teng, C.-H., Wang, M.-C., Tseng, C.-C., Wu, J.-J., Loss of outer membrane protein C in Escherichia coli contributes to both antibiotic resistance and escaping antibody-dependent bactericidal activity. Infect. Immun. 80 (2012), 1815–1822.
    • (2012) Infect. Immun. , vol.80 , pp. 1815-1822
    • Liu, Y.-F.1    Yan, J.-J.2    Lei, H.-Y.3    Teng, C.-H.4    Wang, M.-C.5    Tseng, C.-C.6    Wu, J.-J.7
  • 36
    • 0030861452 scopus 로고    scopus 로고
    • Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elements
    • Lutz, R., Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elements. Nucleic Acids Res. 25 (1997), 1203–1210.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 1203-1210
    • Lutz, R.1
  • 37
    • 84945388093 scopus 로고    scopus 로고
    • Biosensor-driven adaptive laboratory evolution of L-valine production in Corynebacterium glutamicum
    • Mahr, R., Gätgens, C., Gätgens, J., Polen, T., Kalinowski, J., Frunzke, J., Biosensor-driven adaptive laboratory evolution of L-valine production in Corynebacterium glutamicum. Metab. Eng. 32 (2015), 184–194.
    • (2015) Metab. Eng. , vol.32 , pp. 184-194
    • Mahr, R.1    Gätgens, C.2    Gätgens, J.3    Polen, T.4    Kalinowski, J.5    Frunzke, J.6
  • 38
  • 39
    • 84872767064 scopus 로고    scopus 로고
    • Efficient synthesis of L-lactic acid from glycerol by metabolically engineered Escherichia coli
    • Mazumdar, S., Blankschien, M.D., Clomburg, J.M., Gonzalez, R., Efficient synthesis of L-lactic acid from glycerol by metabolically engineered Escherichia coli. Microb. Cell Fact., 12, 2013, 7.
    • (2013) Microb. Cell Fact. , vol.12 , pp. 7
    • Mazumdar, S.1    Blankschien, M.D.2    Clomburg, J.M.3    Gonzalez, R.4
  • 40
    • 84857050180 scopus 로고    scopus 로고
    • Applications of genetically-encoded biosensors for the construction and control of biosynthetic pathways
    • Michener, J.K., Thodey, K., Liang, J.C., Smolke, C.D., Applications of genetically-encoded biosensors for the construction and control of biosynthetic pathways. Metab. Eng. 14 (2012), 212–222.
    • (2012) Metab. Eng. , vol.14 , pp. 212-222
    • Michener, J.K.1    Thodey, K.2    Liang, J.C.3    Smolke, C.D.4
  • 41
    • 84991740197 scopus 로고    scopus 로고
    • Multi-omics quantification of species variation of Escherichia coli links molecular features with strain phenotypes
    • (e12)
    • Monk, J.M., Koza, A., Campodonico, M.A., Machado, D., Seoane, J.M., Palsson, B.O., Herrgård, M.J., Feist, A.M., Multi-omics quantification of species variation of Escherichia coli links molecular features with strain phenotypes. Cell Syst. 3 (2016), 238–251 (e12).
    • (2016) Cell Syst. , vol.3 , pp. 238-251
    • Monk, J.M.1    Koza, A.2    Campodonico, M.A.3    Machado, D.4    Seoane, J.M.5    Palsson, B.O.6    Herrgård, M.J.7    Feist, A.M.8
  • 42
    • 84862193202 scopus 로고    scopus 로고
    • The development and application of a single-cell biosensor for the detection of L-methionine and branched-chain amino acids
    • Mustafi, N., Grünberger, A., Kohlheyer, D., Bott, M., Frunzke, J., The development and application of a single-cell biosensor for the detection of L-methionine and branched-chain amino acids. Metab. Eng. 14 (2012), 449–457.
    • (2012) Metab. Eng. , vol.14 , pp. 449-457
    • Mustafi, N.1    Grünberger, A.2    Kohlheyer, D.3    Bott, M.4    Frunzke, J.5
  • 44
    • 68949163858 scopus 로고    scopus 로고
    • Metabolic flux analysis of Escherichia coli creB and arcA mutants reveals shared control of carbon catabolism under microaerobic growth conditions
    • Nikel, P.I., Zhu, J., San, K.-Y., Méndez, B.S., Bennett, G.N., Metabolic flux analysis of Escherichia coli creB and arcA mutants reveals shared control of carbon catabolism under microaerobic growth conditions. J. Bacteriol. 191 (2009), 5538–5548.
    • (2009) J. Bacteriol. , vol.191 , pp. 5538-5548
    • Nikel, P.I.1    Zhu, J.2    San, K.-Y.3    Méndez, B.S.4    Bennett, G.N.5
  • 45
    • 77950603940 scopus 로고    scopus 로고
    • A mutant Pfu DNA polymerase designed for advanced uracil-excision DNA engineering
    • Nørholm, M.H.H., A mutant Pfu DNA polymerase designed for advanced uracil-excision DNA engineering. BMC Biotechnol., 10, 2010, 21.
    • (2010) BMC Biotechnol. , vol.10 , pp. 21
    • Nørholm, M.H.H.1
  • 48
    • 0029835391 scopus 로고    scopus 로고
    • Cra and the control of carbon flux via metabolic pathways
    • Ramseier, T.M., Cra and the control of carbon flux via metabolic pathways. Res. Microbiol. 147 (1996), 489–493.
    • (1996) Res. Microbiol. , vol.147 , pp. 489-493
    • Ramseier, T.M.1
  • 49
    • 0029147255 scopus 로고
    • The global regulatory protein FruR modulates the direction of carbon flow in Escherichia coli
    • Ramseier, T.W.M., Bledig, S., Michotey, V., Feghali, R., Saier, M.H.J., Saier, M.H., The global regulatory protein FruR modulates the direction of carbon flow in Escherichia coli. Mol. Microbiol. 16 (1995), 1157–1169.
    • (1995) Mol. Microbiol. , vol.16 , pp. 1157-1169
    • Ramseier, T.W.M.1    Bledig, S.2    Michotey, V.3    Feghali, R.4    Saier, M.H.J.5    Saier, M.H.6
  • 50
    • 84992028912 scopus 로고    scopus 로고
    • Genome-wide Escherichia coli stress response and improved tolerance towards industrially relevant chemicals
    • Rau, M.H., Calero, P., Lennen, R.M., Long, K.S., Nielsen, A.T., Genome-wide Escherichia coli stress response and improved tolerance towards industrially relevant chemicals. Microb. Cell Fact., 15, 2016, 176.
    • (2016) Microb. Cell Fact. , vol.15 , pp. 176
    • Rau, M.H.1    Calero, P.2    Lennen, R.M.3    Long, K.S.4    Nielsen, A.T.5
  • 52
    • 34447341173 scopus 로고    scopus 로고
    • Signal integration in the galactose network of Escherichia coli
    • Semsey, S., Krishna, S., Sneppen, K., Adhya, S., Signal integration in the galactose network of Escherichia coli. Mol. Microbiol. 65 (2007), 465–476.
    • (2007) Mol. Microbiol. , vol.65 , pp. 465-476
    • Semsey, S.1    Krishna, S.2    Sneppen, K.3    Adhya, S.4
  • 53
    • 78751473491 scopus 로고    scopus 로고
    • Novel members of the Cra regulon involved in carbon metabolism in Escherichia coli
    • Shimada, T., Yamamoto, K., Ishihama, A., Novel members of the Cra regulon involved in carbon metabolism in Escherichia coli. J. Bacteriol. 193 (2011), 649–659.
    • (2011) J. Bacteriol. , vol.193 , pp. 649-659
    • Shimada, T.1    Yamamoto, K.2    Ishihama, A.3
  • 54
    • 84857912495 scopus 로고    scopus 로고
    • Engineering yield and rate of reductive biotransformation in Escherichia coli by partial cyclization of the pentose phosphate pathway and PTS-independent glucose transport
    • Siedler, S., Bringer, S., Blank, L.M., Bott, M., Engineering yield and rate of reductive biotransformation in Escherichia coli by partial cyclization of the pentose phosphate pathway and PTS-independent glucose transport. Appl. Microbiol. Biotechnol. 93 (2012), 1459–1467.
    • (2012) Appl. Microbiol. Biotechnol. , vol.93 , pp. 1459-1467
    • Siedler, S.1    Bringer, S.2    Blank, L.M.3    Bott, M.4
  • 56
    • 84887778351 scopus 로고    scopus 로고
    • Novel biosensors based on flavonoid-responsive transcriptional regulators introduced into Escherichia coli
    • Siedler, S., Stahlhut, S.G., Malla, S., Maury, J., Neves, A.R., Novel biosensors based on flavonoid-responsive transcriptional regulators introduced into Escherichia coli. Metab. Eng. 21 (2014), 2–8.
    • (2014) Metab. Eng. , vol.21 , pp. 2-8
    • Siedler, S.1    Stahlhut, S.G.2    Malla, S.3    Maury, J.4    Neves, A.R.5
  • 58
    • 49649156182 scopus 로고
    • The regulation of ribose-5-phosphate isomerisation in Escherichia coli K12
    • Skinner, A.J., Cooper, R.A., The regulation of ribose-5-phosphate isomerisation in Escherichia coli K12. FEBS Lett. 12 (1971), 293–296.
    • (1971) FEBS Lett. , vol.12 , pp. 293-296
    • Skinner, A.J.1    Cooper, R.A.2
  • 59
    • 0030060223 scopus 로고    scopus 로고
    • Ribose catabolism of Escherichia coli: characterization of the rpiB gene encoding ribose phosphate isomerase B and of the rpiR gene, which is involved in regulation of rpiB expression
    • Sørensen, K.I., Hove-Jensen, B., Ribose catabolism of Escherichia coli: characterization of the rpiB gene encoding ribose phosphate isomerase B and of the rpiR gene, which is involved in regulation of rpiB expression. J. Bacteriol. 178 (1996), 1003–1011.
    • (1996) J. Bacteriol. , vol.178 , pp. 1003-1011
    • Sørensen, K.I.1    Hove-Jensen, B.2
  • 60
    • 79251580632 scopus 로고    scopus 로고
    • Design and application of a mevalonate-responsive regulatory protein
    • Tang, S.-Y., Cirino, P.C., Design and application of a mevalonate-responsive regulatory protein. Angew. Chemie Int. Ed, 50, 2011, 1084–1086.
    • (2011) Angew. Chemie Int. Ed , vol.50 , pp. 1084-1086
    • Tang, S.-Y.1    Cirino, P.C.2
  • 61
    • 84879999713 scopus 로고    scopus 로고
    • Screening for enhanced triacetic acid lactone production by recombinant Escherichia coli expressing a designed triacetic acid lactone reporter
    • Tang, S.-Y., Qian, S., Akinterinwa, O., Frei, C.S., Gredell, J.A., Cirino, P.C., Screening for enhanced triacetic acid lactone production by recombinant Escherichia coli expressing a designed triacetic acid lactone reporter. J. Am. Chem. Soc. 135 (2013), 10099–10103.
    • (2013) J. Am. Chem. Soc. , vol.135 , pp. 10099-10103
    • Tang, S.-Y.1    Qian, S.2    Akinterinwa, O.3    Frei, C.S.4    Gredell, J.A.5    Cirino, P.C.6
  • 63
    • 84946735654 scopus 로고    scopus 로고
    • Gene Ontology Consortium: going forward
    • The Gene Ontology Consortium, Gene Ontology Consortium: going forward. Nucleic Acids Res. 43 (2015), D1049–D1056.
    • (2015) Nucleic Acids Res. , vol.43 , pp. D1049-D1056
    • The Gene Ontology Consortium1
  • 64
    • 79952116643 scopus 로고    scopus 로고
    • Substrate-induced gene expression screening: a method for high-throughput screening of metagenome libraries
    • In
    • Uchiyama T., Miyazaki K., 2010. Substrate-induced gene expression screening: a method for high-throughput screening of metagenome libraries. In pp. 153–168.
    • (2010) , pp. 153-168
    • Uchiyama, T.1    Miyazaki, K.2
  • 65
    • 33646578756 scopus 로고    scopus 로고
    • Overflow metabolism in Escherichia coli during steady-state grwoth: transcriptional regulation and effect of the redox ratio
    • Vermuri, G.N., Altman, E., Sangurdekar, D.P., Khodursky, A.B., Eiteman, Overflow metabolism in Escherichia coli during steady-state grwoth: transcriptional regulation and effect of the redox ratio. Appl. Environ. Microbiol. 72:5 (2006), 3653–3661.
    • (2006) Appl. Environ. Microbiol. , vol.72 , Issue.5 , pp. 3653-3661
    • Vermuri, G.N.1    Altman, E.2    Sangurdekar, D.P.3    Khodursky, A.B.4    Eiteman5
  • 67
    • 68949161807 scopus 로고    scopus 로고
    • Programming cells by multiplex genome engineering and accelerated evolution
    • Wang, H.H., Isaacs, F.J., Carr, P.A., Sun, Z.Z., Xu, G., Forest, C.R., Church, G.M., Programming cells by multiplex genome engineering and accelerated evolution. Nature 460 (2009), 894–898.
    • (2009) Nature , vol.460 , pp. 894-898
    • Wang, H.H.1    Isaacs, F.J.2    Carr, P.A.3    Sun, Z.Z.4    Xu, G.5    Forest, C.R.6    Church, G.M.7
  • 68
    • 0026682712 scopus 로고
    • Isorepressor of the gal regulon in Escherichia coli
    • Weickert, M.J., Adhya, S., Isorepressor of the gal regulon in Escherichia coli. J. Mol. Biol. 226 (1992), 69–83.
    • (1992) J. Mol. Biol. , vol.226 , pp. 69-83
    • Weickert, M.J.1    Adhya, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.