Metabolic engineering of Escherichia coli to minimize byproduct formate and improving succinate productivity through increasing NADH availability by heterologous expression of NAD+-dependent formate dehydrogenase

Metabolic Engineering

Volumn 20, Issue , 2013, Pages 1-8

  Balzer, Grant J ^a   Thakker, Chandresh ^b   Bennett, George N ^b   San, Ka Yiu ^a  

^a Rice University   (United States)

^b RICE UNIVERSITY   (United States)

Author keywords

Byproduct; E. coli; Formate; Formate dehydrogenase; NADH; Succinate

Indexed keywords

CARBON DIOXIDE; ESCHERICHIA COLI; FERMENTATION; GLUCOSE; PRODUCTIVITY; PURIFICATION; VOLATILE FATTY ACIDS; WASTE DISPOSAL;

E. COLI; FORMATE; FORMATE DEHYDROGENASE; NADH; SUCCINATE;

BYPRODUCTS;

FORMATE DEHYDROGENASE; FORMIC ACID; GLUCOSE; NICOTINAMIDE ADENINE DINUCLEOTIDE; PYRUVATE CARBOXYLASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SUCCINIC ACID;

ARTICLE; BACTERIAL STRAIN; BACTERIUM CULTURE; BATCH REACTOR; BINDING SITE; BIOAVAILABILITY; CANDIDA BOIDINII; CELL DENSITY; CULTURE MEDIUM; DOWNSTREAM PROCESSING; ESCHERICHIA COLI; FERMENTATION; GLUCOSE INTAKE; HETEROLOGOUS EXPRESSION; LACTOCOCCUS LACTIS; METABOLIC ENGINEERING; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; WASTE DISPOSAL;

CANDIDA BOIDINII; ESCHERICHIA COLI; LACTOCOCCUS LACTIS;

BYPRODUCT; E. COLI; FORMATE; FORMATE DEHYDROGENASE; NADH; SUCCINATE;

BACTERIAL PROTEINS; CANDIDA; ESCHERICHIA COLI; FORMATE DEHYDROGENASES; FORMATES; FUNGAL PROTEINS; GENE EXPRESSION; LACTOCOCCUS LACTIS; METABOLIC ENGINEERING; NAD; PYRUVATE CARBOXYLASE; SUCCINIC ACID;

EID: 84881512097     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2013.07.005     Document Type: Article

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