Loss of outer membrane protein C in Escherichia coli contributes to both antibiotic resistance and escaping antibody-dependent bactericidal activity

Infection and Immunity

Volumn 80, Issue 5, 2012, Pages 1815-1822

  Liu, Yi Fang ^a   Yan, Jing Jou ^d   Lei, Huan Yao ^e   Teng, Ching Hao ^c   Wang, Ming Cheng ^b,g   Tseng, Chin Chung ^g   Wu, Jiunn Jong ^f,h,i  

^a Institute of Basic Medical Sciences   (Taiwan)

^b Clinical Pharmacy   (Taiwan)

^c Molecular Medicine   (Taiwan)

^d Departments of Pathology   (Taiwan)

^e Department of Pathology Microbiology and Immunology   (Taiwan)

^f Medical Laboratory Science and Biotechnology   (Taiwan)

^g NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^h Department of Internal Medicine ^*  (Taiwan)

ⁱ NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CARBAPENEM; CEFEPIME; COMPLEMENT COMPONENT C1Q; OUTER MEMBRANE PROTEIN C;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL SURVIVAL; BACTERIAL VIRULENCE; BACTERICIDAL ACTIVITY; BACTERIUM MUTANT; ESCHERICHIA COLI; GENE SILENCING; NATURAL SELECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN INTERACTION; WILD TYPE;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIBODIES, BACTERIAL; ANTIBODY SPECIFICITY; ANTIGENS, BACTERIAL; COMPLEMENT C1Q; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; GENOTYPE; HUMANS; MICE; MICE, INBRED BALB C; MUTATION; PORINS; RECOMBINANT PROTEINS;

EID: 84861144335     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.06395-11     Document Type: Article

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