Quantitative Imaging Approaches to Study the CAR Immunological Synapse

Molecular Therapy

Volumn 25, Issue 8, 2017, Pages 1757-1768

  Mukherjee, Malini ^a,b   Mace, Emily M ^a,b   Carisey, Alexandre F ^a,b   Ahmed, Nabil ^a   Orange, Jordan S ^a,b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b TEXAS CHILDREN S HOSPITAL   (United States)

Author keywords

CAR; chimeric antigen receptor; confocal microscopy; immune synapse; live imaging microscopy; quantitative image analysis

Indexed keywords

CHIMERIC ANTIGEN RECEPTOR; F ACTIN; ANTIGEN; HYBRID PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR;

CELL BEHAVIOR ASSAY; CONFOCAL MICROSCOPY; CYTOTOXICITY; IMMUNOLOGICAL SYNAPSE; MICROSCOPY; MICROTUBULE ORGANIZING CENTER; NATURAL KILLER CELL; PROCESS OPTIMIZATION; PROTEIN AGGREGATION; PROTEIN POLYMERIZATION; PROTEIN STRUCTURE; QUANTITATIVE ASSAY; REVIEW; T LYMPHOCYTE; VALIDATION PROCESS; ANIMAL; BIOTECHNOLOGY; CHEMISTRY; CYTOTOXIC T LYMPHOCYTE; GENETICS; HUMAN; IMMUNOLOGY; IMMUNOTHERAPY; METABOLISM; MOLECULAR IMAGING; PROCEDURES;

ANIMALS; ANTIGENS; BIOTECHNOLOGY; CYTOTOXICITY, IMMUNOLOGIC; HUMANS; IMMUNOLOGICAL SYNAPSES; IMMUNOTHERAPY; KILLER CELLS, NATURAL; MICROSCOPY; MOLECULAR IMAGING; RECEPTORS, ANTIGEN, T-CELL; RECOMBINANT FUSION PROTEINS; T-LYMPHOCYTES, CYTOTOXIC;

EID: 85021076860     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1016/j.ymthe.2017.06.003     Document Type: Review

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