-
1
-
-
84861122295
-
The future is now: Chimeric antigen receptors as new targeted therapies for childhood cancer
-
Lee, D.W. et al. The future is now: chimeric antigen receptors as new targeted therapies for childhood cancer. Clin. Cancer Res. 18, 2780-2790 (2012).
-
(2012)
Clin. Cancer Res
, vol.18
, pp. 2780-2790
-
-
Lee, D.W.1
-
2
-
-
84877669593
-
The basic principles of chimeric antigen receptor design
-
Sadelain, M., Brentjens, R. & Rivière, I. The basic principles of chimeric antigen receptor design. Cancer Discovery 3, 388-398 (2013).
-
(2013)
Cancer Discovery
, vol.3
, pp. 388-398
-
-
Sadelain, M.1
Brentjens, R.2
Rivière, I.3
-
3
-
-
84923019006
-
T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: A phase 1 dose-escalation trial
-
Lee, D.W. et al. T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial. Lancet 385, 517-528 (2015).
-
(2015)
Lancet
, vol.385
, pp. 517-528
-
-
Lee, D.W.1
-
4
-
-
84908073316
-
Chimeric antigen receptor T cells for sustained remissions in leukemia
-
Maude, S.L. et al. Chimeric antigen receptor T cells for sustained remissions in leukemia. N. Engl. J. Med. 371, 1507-1517 (2014).
-
(2014)
N. Engl. J. Med
, vol.371
, pp. 1507-1517
-
-
Maude, S.L.1
-
5
-
-
84863337890
-
B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells
-
Kochenderfer, J.N. et al. B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells. Blood 119, 2709-2720 (2012).
-
(2012)
Blood
, vol.119
, pp. 2709-2720
-
-
Kochenderfer, J.N.1
-
6
-
-
80051720194
-
Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
-
Porter, D.L. et al. Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. N. Engl. J. Med. 365, 725-733 (2011).
-
(2011)
N. Engl. J. Med
, vol.365
, pp. 725-733
-
-
Porter, D.L.1
-
7
-
-
84876325876
-
Chimeric antigen receptor-modified T cells for acute lymphoid leukemia
-
Grupp, S.A. et al. Chimeric antigen receptor-modified T cells for acute lymphoid leukemia. N. Engl. J. Med. 368, 1509-1518 (2013).
-
(2013)
N. Engl. J. Med
, vol.368
, pp. 1509-1518
-
-
Grupp, S.A.1
-
8
-
-
79955517235
-
CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients
-
Savoldo, B. et al. CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients. J. Clin. Invest. 121, 1822-1826 (2011).
-
(2011)
J. Clin. Invest
, vol.121
, pp. 1822-1826
-
-
Savoldo, B.1
-
9
-
-
84876005284
-
CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia
-
Brentjens, R.J. et al. CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia. Sci. Transl. Med. 5, 177ra138 (2013).
-
(2013)
Sci. Transl. Med
, vol.5
-
-
Brentjens, R.J.1
-
10
-
-
84896335556
-
Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia
-
Davila, M.L. et al. Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia. Sci. Transl. Med. 6, 224ra225 (2014).
-
(2014)
Sci. Transl. Med
, vol.6
-
-
Davila, M.L.1
-
11
-
-
33750699642
-
A phase i study on adoptive immunotherapy using gene-modified T cells for ovarian cancer
-
Kershaw, M.H. et al. A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer. Clin. Cancer Res. 12, 6106-6115 (2006).
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 6106-6115
-
-
Kershaw, M.H.1
-
12
-
-
33947265424
-
Adoptive transfer of chimeric antigen receptor re-directed cytolytic T lymphocyte clones in patients with neuroblastoma
-
Park, J.R. et al. Adoptive transfer of chimeric antigen receptor re-directed cytolytic T lymphocyte clones in patients with neuroblastoma. Mol. Ther. 15, 825-833 (2007).
-
(2007)
Mol. Ther
, vol.15
, pp. 825-833
-
-
Park, J.R.1
-
13
-
-
55549145071
-
Virus-specific T cells engineered to coexpress tumor-specific receptors: Persistence and antitumor activity in individuals with neuroblastoma
-
Pule, M.A. et al. Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma. Nat. Med. 14, 1264-1270 (2008).
-
(2008)
Nat. Med
, vol.14
, pp. 1264-1270
-
-
Pule, M.A.1
-
14
-
-
82955207691
-
Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma
-
Louis, C.U. et al. Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma. Blood 118, 6050-6056 (2011).
-
(2011)
Blood
, vol.118
, pp. 6050-6056
-
-
Louis, C.U.1
-
15
-
-
84860333968
-
CD20-specific adoptive immunotherapy for lymphoma using a chimeric antigen receptor with both CD28 and 4-1BB domains: Pilot clinical trial results
-
Till, B.G. et al. CD20-specific adoptive immunotherapy for lymphoma using a chimeric antigen receptor with both CD28 and 4-1BB domains: pilot clinical trial results. Blood 119, 3940-3950 (2012).
-
(2012)
Blood
, vol.119
, pp. 3940-3950
-
-
Till, B.G.1
-
16
-
-
84878605813
-
Treatment of metastatic renal cell carcinoma with CAIX CAR-engineered T cells: Clinical evaluation and management of on-target toxicity
-
Lamers, C.H.J. et al. Treatment of metastatic renal cell carcinoma with CAIX CAR-engineered T cells: clinical evaluation and management of on-target toxicity. Mol. Ther. 21, 904-912 (2013).
-
(2013)
Mol. Ther
, vol.21
, pp. 904-912
-
-
Lamers, C.H.J.1
-
17
-
-
10344261422
-
Cutting edge: Persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy
-
Robbins, P.F. et al. Cutting edge: persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy. J. Immunol. 173, 7125-7130 (2004).
-
(2004)
J. Immunol
, vol.173
, pp. 7125-7130
-
-
Robbins, P.F.1
-
18
-
-
33845294816
-
CD28 costimulation provided through a CD19-specific chimeric antigen receptor enhances in vivo persistence and antitumor efficacy of adoptively transferred T cells
-
Kowolik, C.M. et al. CD28 costimulation provided through a CD19-specific chimeric antigen receptor enhances in vivo persistence and antitumor efficacy of adoptively transferred T cells. Cancer Res. 66, 10995-11004 (2006).
-
(2006)
Cancer Res
, vol.66
, pp. 10995-11004
-
-
Kowolik, C.M.1
-
19
-
-
70350726110
-
Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo
-
Milone, M.C. et al. Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo. Mol. Ther. 17, 1453-1464 (2009).
-
(2009)
Mol. Ther
, vol.17
, pp. 1453-1464
-
-
Milone, M.C.1
-
20
-
-
84874027123
-
Anti-CD22-chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia
-
Haso, W. et al. Anti-CD22-chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia. Blood 121, 1165-1174 (2013).
-
(2013)
Blood
, vol.121
, pp. 1165-1174
-
-
Haso, W.1
-
21
-
-
70349569569
-
Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
-
Ahmadzadeh, M. et al. Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired. Blood 114, 1537-1544 (2009).
-
(2009)
Blood
, vol.114
, pp. 1537-1544
-
-
Ahmadzadeh, M.1
-
22
-
-
77957744369
-
Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity
-
Sakuishi, K. et al. Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity. J. Exp. Med. 207, 2187-2194 (2010).
-
(2010)
J. Exp. Med
, vol.207
, pp. 2187-2194
-
-
Sakuishi, K.1
-
23
-
-
79957925314
-
Exhaustion of tumor-specific CD8+ T cells in metastases from melanoma patients
-
Baitsch, L. et al. Exhaustion of tumor-specific CD8+ T cells in metastases from melanoma patients. J. Clin. Invest. 121, 2350-2360 (2011).
-
(2011)
J. Clin. Invest
, vol.121
, pp. 2350-2360
-
-
Baitsch, L.1
-
24
-
-
79955977180
-
Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia
-
Zhou, Q. et al. Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia. Blood 117, 4501-4510 (2011).
-
(2011)
Blood
, vol.117
, pp. 4501-4510
-
-
Zhou, Q.1
-
25
-
-
84863115998
-
Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape
-
Woo, S.-R. et al. Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape. Cancer Res. 72, 917-927 (2012).
-
(2012)
Cancer Res
, vol.72
, pp. 917-927
-
-
Woo, S.-R.1
-
26
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian, S.L. et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N. Engl. J. Med. 366, 2443-2454 (2012).
-
(2012)
N. Engl. J. Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
-
27
-
-
67649660551
-
Redefining chronic viral infection
-
Virgin, H.W., Wherry, E.J. & Ahmed, R. Redefining chronic viral infection. Cell 138, 30-50 (2009).
-
(2009)
Cell
, vol.138
, pp. 30-50
-
-
Virgin, H.W.1
Wherry, E.J.2
Ahmed, R.3
-
28
-
-
79956077563
-
T cell exhaustion
-
Wherry, E.J. T cell exhaustion. Nat. Immunol. 12, 492-499 (2011).
-
(2011)
Nat. Immunol
, vol.12
, pp. 492-499
-
-
Wherry, E.J.1
-
29
-
-
0035888244
-
Targeting of GD2-positive tumor cells by human T lymphocytes engineered to express chimeric T-cell receptor genes
-
Rossig, C. et al. Targeting of GD2-positive tumor cells by human T lymphocytes engineered to express chimeric T-cell receptor genes. Int. J. Cancer 94, 228-236 (2001).
-
(2001)
Int. J. Cancer
, vol.94
, pp. 228-236
-
-
Rossig, C.1
-
30
-
-
27744566329
-
A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells
-
Pulè, M.A. et al. A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells. Mol. Ther. 12, 933-941 (2005).
-
(2005)
Mol. Ther
, vol.12
, pp. 933-941
-
-
Pulè, M.A.1
-
31
-
-
84953344459
-
The non-signaling extracellular spacer domain of chimeric antigen receptors is decisive for in vivo antitumor activity
-
Hudecek, M. et al. The non-signaling extracellular spacer domain of chimeric antigen receptors is decisive for in vivo antitumor activity. Cancer Immunol. Res. 3, 125-135 (2014).
-
(2014)
Cancer Immunol. Res
, vol.3
, pp. 125-135
-
-
Hudecek, M.1
-
32
-
-
68449088813
-
Construction and pre-clinical evaluation of an anti-CD19 chimeric antigen receptor
-
Kochenderfer, J.N. et al. Construction and pre-clinical evaluation of an anti-CD19 chimeric antigen receptor. J. Immunother. 32, 689-702 (2009).
-
(2009)
J. Immunother
, vol.32
, pp. 689-702
-
-
Kochenderfer, J.N.1
-
33
-
-
68649096424
-
A role for the transcriptional repressor Blimp-1 in CD8+ T cell exhaustion during chronic viral infection
-
Shin, H. et al. A role for the transcriptional repressor Blimp-1 in CD8+ T cell exhaustion during chronic viral infection. Immunity 31, 309-320 (2009).
-
(2009)
Immunity
, vol.31
, pp. 309-320
-
-
Shin, H.1
-
34
-
-
84870922385
-
Network analysis reveals centrally connected genes and pathways involved in CD8+ T cell exhaustion versus memory
-
Doering, T.A. et al. Network analysis reveals centrally connected genes and pathways involved in CD8+ T cell exhaustion versus memory. Immunity 37, 1130-1144 (2012).
-
(2012)
Immunity
, vol.37
, pp. 1130-1144
-
-
Doering, T.A.1
-
35
-
-
84870230232
-
Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection
-
Paley, M.A. et al. Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection. Science 338, 1220-1225 (2012).
-
(2012)
Science
, vol.338
, pp. 1220-1225
-
-
Paley, M.A.1
-
36
-
-
33748468629
-
A dose-dependent requirement for the proline motif of CD28 in cellular and humoral immunity revealed by a targeted knockin mutant
-
Friend, L.D. et al. A dose-dependent requirement for the proline motif of CD28 in cellular and humoral immunity revealed by a targeted knockin mutant. J. Exp. Med. 203, 2121-2133 (2006).
-
(2006)
J. Exp. Med
, vol.203
, pp. 2121-2133
-
-
Friend, L.D.1
-
37
-
-
67650072922
-
Targeted knock-in mice expressing mutations of CD28 reveal an essential pathway for costimulation
-
Dodson, L.F. et al. Targeted knock-in mice expressing mutations of CD28 reveal an essential pathway for costimulation. Mol. Cell. Biol. 29, 3710-3721 (2009).
-
(2009)
Mol. Cell. Biol
, vol.29
, pp. 3710-3721
-
-
Dodson, L.F.1
-
38
-
-
76749120309
-
A herceptin-based chimeric antigen receptor with modified signaling domains leads to enhanced survival of transduced T lymphocytes and antitumor activity
-
Zhao, Y. et al. A herceptin-based chimeric antigen receptor with modified signaling domains leads to enhanced survival of transduced T lymphocytes and antitumor activity. J. Immunol. 183, 5563-5574 (2009).
-
(2009)
J. Immunol
, vol.183
, pp. 5563-5574
-
-
Zhao, Y.1
-
39
-
-
0030965970
-
Disrupting the hydrophobic patches at the antibody variable/constant domain interface: Improved in vivo folding and physical characterization of an engineered scFv fragment
-
Nieba, L., Honegger, A., Krebber, C. & Plückthun, A. Disrupting the hydrophobic patches at the antibody variable/constant domain interface: improved in vivo folding and physical characterization of an engineered scFv fragment. Protein Eng. 10, 435-444 (1997).
-
(1997)
Protein Eng
, vol.10
, pp. 435-444
-
-
Nieba, L.1
Honegger, A.2
Krebber, C.3
Plückthun, A.4
-
40
-
-
0037252433
-
Single-chain Fv multimers of the anti-neuraminidase antibody NC10: The residue at position 15 in the VL domain of the scFv-0 (VL- VH) molecule is primarily responsible for formation of a tetramer-trimer equilibrium
-
Dolezal, O. et al. Single-chain Fv multimers of the anti-neuraminidase antibody NC10: the residue at position 15 in the VL domain of the scFv-0 (VL- VH) molecule is primarily responsible for formation of a tetramer-trimer equilibrium. Protein Eng. 16, 47-56 (2003).
-
(2003)
Protein Eng
, vol.16
, pp. 47-56
-
-
Dolezal, O.1
-
41
-
-
0028074723
-
Multivalent Fvs: Characterization of single-chain Fv oligomers and preparation of a bispecific Fv
-
Whitlow, M. et al. Multivalent Fvs: characterization of single-chain Fv oligomers and preparation of a bispecific Fv. Protein Eng. 7, 1017-1026 (1994).
-
(1994)
Protein Eng
, vol.7
, pp. 1017-1026
-
-
Whitlow, M.1
-
42
-
-
35349014587
-
Molecular signature of CD8+ T cell exhaustion during chronic viral infection
-
Wherry, E.J. et al. Molecular signature of CD8+ T cell exhaustion during chronic viral infection. Immunity 27, 670-684 (2007).
-
(2007)
Immunity
, vol.27
, pp. 670-684
-
-
Wherry, E.J.1
-
43
-
-
84894258518
-
Molecular and transcriptional basis of CD4+ T cell dysfunction during chronic infection
-
Crawford, A. et al. Molecular and transcriptional basis of CD4+ T cell dysfunction during chronic infection. Immunity 40, 289-302 (2014).
-
(2014)
Immunity
, vol.40
, pp. 289-302
-
-
Crawford, A.1
-
44
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian, A. et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl. Acad. Sci. USA 102, 15545-15550 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
-
45
-
-
20944439742
-
The role of extracellular spacer regions in the optimal design of chimeric immune receptors: Evaluation of four different scFvs and antigens
-
Guest, R.D. et al. The role of extracellular spacer regions in the optimal design of chimeric immune receptors: evaluation of four different scFvs and antigens. J. Immunother. 28, 203-211 (2005).
-
(2005)
J. Immunother
, vol.28
, pp. 203-211
-
-
Guest, R.D.1
-
46
-
-
45549093089
-
Antigen sensitivity of CD22-specific chimeric TCR is modulated by target epitope distance from the cell membrane
-
James, S.E. et al. Antigen sensitivity of CD22-specific chimeric TCR is modulated by target epitope distance from the cell membrane. J. Immunol. 180, 7028-7038 (2008).
-
(2008)
J. Immunol
, vol.180
, pp. 7028-7038
-
-
James, S.E.1
-
47
-
-
84962213143
-
Identification of chimeric antigen receptors that mediate constitutive or inducible proliferation of T cells
-
Frigault, M.J. et al. Identification of chimeric antigen receptors that mediate constitutive or inducible proliferation of T cells. Cancer Immunol. Res. http://dx.doi.org/10.1158/2326-6066.CIR-14-0186 (2015).
-
(2015)
Cancer Immunol. Res
-
-
Frigault, M.J.1
-
48
-
-
34248399247
-
Impaired NFAT nuclear translocation results in split exhaustion of virus-specific CD8+ T cell functions during chronic viral infection
-
Agnellini, P. et al. Impaired NFAT nuclear translocation results in split exhaustion of virus-specific CD8+ T cell functions during chronic viral infection. Proc. Natl. Acad. Sci. USA 104, 4565-4570 (2007).
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 4565-4570
-
-
Agnellini, P.1
-
49
-
-
80051925716
-
4-1BB signaling synergizes with programmed death ligand 1 blockade to augment CD8 T cell responses during chronic viral infection
-
Vezys, V. et al. 4-1BB signaling synergizes with programmed death ligand 1 blockade to augment CD8 T cell responses during chronic viral infection. J. Immunol. 187, 1634-1642 (2011).
-
(2011)
J. Immunol
, vol.187
, pp. 1634-1642
-
-
Vezys, V.1
-
50
-
-
40049091217
-
4-1BBL induces TNF receptor-associated factor 1-dependent Bim modulation in human T cells and is a critical component in the costimulation-dependent rescue of functionally impaired HIV-specific CD8 T cells
-
Wang, C. et al. 4-1BBL induces TNF receptor-associated factor 1-dependent Bim modulation in human T cells and is a critical component in the costimulation-dependent rescue of functionally impaired HIV-specific CD8 T cells. J. Immunol. 179, 8252-8263 (2007).
-
(2007)
J. Immunol
, vol.179
, pp. 8252-8263
-
-
Wang, C.1
-
51
-
-
84891305352
-
Chimeric antigen receptor modified T cells directed against CD19 (CTL019 cells) have long-term persistence and induce durable responses in relapsed, refractory CLL
-
Dittus, C. et al. Chimeric antigen receptor modified T cells directed against CD19 (CTL019 cells) have long-term persistence and induce durable responses in relapsed, refractory CLL. Blood 122, 4162 (2013).
-
(2013)
Blood
, vol.122
, pp. 4162
-
-
Dittus, C.1
-
52
-
-
84886672916
-
Hypoxia-inducible factors enhance the effector responses of CD8+ T cells to persistent antigen
-
Doedens, A.L. et al. Hypoxia-inducible factors enhance the effector responses of CD8+ T cells to persistent antigen. Nat. Immunol. 14, 1173-1182 (2013).
-
(2013)
Nat. Immunol
, vol.14
, pp. 1173-1182
-
-
Doedens, A.L.1
-
53
-
-
67650096912
-
Enhancing CD8 T-cell memory by modulating fatty acid metabolism
-
Pearce, E.L. et al. Enhancing CD8 T-cell memory by modulating fatty acid metabolism. Nature 460, 103-107 (2009).
-
(2009)
Nature
, vol.460
, pp. 103-107
-
-
Pearce, E.L.1
-
54
-
-
84856183120
-
Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development
-
van der Windt, G.J. et al. Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development. Immunity 36, 68-78 (2012).
-
(2012)
Immunity
, vol.36
, pp. 68-78
-
-
Van Der Windt, G.J.1
-
55
-
-
67650074206
-
MTOR regulates memory CD8 T-cell differentiation
-
Araki, K. et al. mTOR regulates memory CD8 T-cell differentiation. Nature 460, 108-112 (2009).
-
(2009)
Nature
, vol.460
, pp. 108-112
-
-
Araki, K.1
-
56
-
-
79251515158
-
SPICE: Exploration and analysis of post-cytometric complex multivariate datasets
-
Roederer, M., Nozzi, J.L. & Nason, M.C. SPICE: Exploration and analysis of post-cytometric complex multivariate datasets. Cytometry A 79, 167-174 (2011).
-
(2011)
Cytometry A
, vol.79
, pp. 167-174
-
-
Roederer, M.1
Nozzi, J.L.2
Nason, M.C.3
-
57
-
-
84875198775
-
Recognition of glioma stem cells by genetically modified T cells targeting EGFRvIII and development of adoptive cell therapy for glioma
-
Morgan, R.A. et al. Recognition of glioma stem cells by genetically modified T cells targeting EGFRvIII and development of adoptive cell therapy for glioma. Hum. Gene Ther. 23, 1043-1053 (2012).
-
(2012)
Hum. Gene Ther
, vol.23
, pp. 1043-1053
-
-
Morgan, R.A.1
-
58
-
-
48449094247
-
IMGT/V-QUEST: The highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis
-
Brochet, X., Lefranc, M.-P. & Giudicelli, V. IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis. Nucleic Acids Res. 36 (suppl. 2), W503-W508 (2008).
-
(2008)
Nucleic Acids Res
, vol.36
, pp. W503-W508
-
-
Brochet, X.1
Lefranc, M.-P.2
Giudicelli, V.3
-
59
-
-
0031963116
-
Induction of IgG antibodies by an anti-idiotype antibody mimicking disialoganglioside GD2
-
Sen, G. et al. Induction of IgG antibodies by an anti-idiotype antibody mimicking disialoganglioside GD2. J. Immunother. 21, 75-83 (1998).
-
(1998)
J. Immunother
, vol.21
, pp. 75-83
-
-
Sen, G.1
-
60
-
-
84874574104
-
Chimeric antigen receptor (CAR)-specific monoclonal antibody to detect CD19-specific T cells in clinical trials
-
Jena, B. et al. Chimeric antigen receptor (CAR)-specific monoclonal antibody to detect CD19-specific T cells in clinical trials. PLoS ONE 8, e57838 (2013).
-
(2013)
PLoS ONE
, vol.8
-
-
Jena, B.1
-
61
-
-
77957714521
-
Computer control of microscopes using μmanager
-
14.20.1-14.20.17
-
Edelstein, A. et al. Computer control of microscopes using μManager. Curr. Protoc. Mol. Biol. 92, 14.20.1-14.20.17 (2010).
-
(2010)
Curr. Protoc. Mol. Biol
, vol.92
-
-
Edelstein, A.1
-
62
-
-
12244312784
-
Characterization of one-and two-photon excitation fluorescence resonance energy transfer microscopy
-
Elangovan, M. et al. Characterization of one-and two-photon excitation fluorescence resonance energy transfer microscopy. Methods 29, 58-73 (2003).
-
(2003)
Methods
, vol.29
, pp. 58-73
-
-
Elangovan, M.1
-
63
-
-
84862520770
-
Fiji: An open-source platform for biological-image analysis
-
Schindelin, J. et al. Fiji: an open-source platform for biological-image analysis. Nat. Methods 9, 676-682 (2012).
-
(2012)
Nat. Methods
, vol.9
, pp. 676-682
-
-
Schindelin, J.1
-
64
-
-
39349104144
-
The fluorescent protein color palette
-
21.5
-
Olenych, S.G., Claxton, N.S., Ottenberg, G.K. & Davidson, M.W. The fluorescent protein color palette. Curr. Protoc. Cell Biol. 21, 21.5 (2007).
-
(2007)
Curr. Protoc. Cell Biol
, vol.21
-
-
Olenych, S.G.1
Claxton, N.S.2
Ottenberg, G.K.3
Davidson, M.W.4
-
65
-
-
84880848605
-
IL-7/anti-IL-7 mAb complexes augment cytokine potency in mice through association with IgG-Fc and by competition with IL-7R
-
Martin, C.E. et al. IL-7/anti-IL-7 mAb complexes augment cytokine potency in mice through association with IgG-Fc and by competition with IL-7R. Blood 121, 4484-4492 (2013).
-
(2013)
Blood
, vol.121
, pp. 4484-4492
-
-
Martin, C.E.1
|