Phosphorylation of the myosin IIA tailpiece regulates single myosin IIA molecule association with lytic granules to promote NK-cell cytotoxicity

Blood

Volumn 118, Issue 22, 2011, Pages 5862-5871

  Sanborn, Keri B ^a,b   Mace, Emily M ^b   Rak, Gregory D ^a,b   Difeo, Analisa ^c   Martignetti, John A ^c   Pecci, Alessandro ^d   Bussel, James B ^e   Favier, Rémi ^f   Orange, Jordan S ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF PAVIA   (Italy)

^e WEILL CORNELL MEDICAL COLLEGE   (United States)

^f ARMAND TROUSSEAU HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

MYOSIN HEAVY CHAIN; MYOSIN IIA; SERINE;

ARTICLE; CELL FUNCTION; CELL GRANULE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXICITY; EXOCYTOSIS; HUMAN; HUMAN CELL; MUTATION; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION;

EID: 82155184487     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-03-344846     Document Type: Article

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