In Vivo Killing Capacity of Cytotoxic T Cells Is Limited and Involves Dynamic Interactions and T Cell Cooperativity

Immunity

Volumn 44, Issue 2, 2016, Pages 233-245

  Halle, Stephan ^a   Keyser, Kirsten Anja ^a   Stahl, Felix Rolf ^a,g   Busche, Andreas ^a,h   Marquardt, Anja ^a,i   Zheng, Xiang ^a   Galla, Melanie ^a   Heissmeyer, Vigo ^b,c   Heller, Katrin ^a   Boelter, Jasmin ^a   Wagner, Karen ^a   Bischoff, Yvonne ^a   Martens, Rieke ^a   Braun, Asolina ^a,j   Werth, Kathrin ^a   Uvarovskii, Alexey ^d   Kempf, Harald ^d   Meyer Hermann, Michael ^d,e   Arens, Ramon ^f   Kremer, Melanie ^b   Sutter, Gerd ^b   Messerle, Martin ^a   Förster, Reinhold ^a   more..

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^e TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

^f LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^g UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^h Merck Animal Health Burgwedel Biotech GmbH   (Germany)

ⁱ Octapharma Produktionsgesellschaft Deutschland mbH   (Germany)

^j UNIVERSITY OF MELBOURNE   (Australia)

more..

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROTEIN GCAMP6; UNCLASSIFIED DRUG; VIRUS PROTEIN; PERFORIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTATION; ANTIVIRAL ACTIVITY; ARTICLE; CD8+ T LYMPHOCYTE; CELL INTERACTION; CELL MEDIATED CYTOTOXICITY; CELL MIGRATION; CELL MOTILITY; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; CYTOTOXIC T LYMPHOCYTE; DOWN REGULATION; EPIFLUORESCENCE MICROSCOPY; FEMALE; HERPES VIRUS INFECTION; IMMUNE EVASION; IMMUNOLOGICAL SYNAPSE; IN VIVO STUDY; LYMPHOCYTE FUNCTION; MALE; MATHEMATICAL MODEL; MOUSE; MULTIPHOTON MICROSCOPY; NONHUMAN; POXVIRUS INFECTION; PRIORITY JOURNAL; T LYMPHOCYTE; ANIMAL; C57BL MOUSE; CALCIUM SIGNALING; CELL COMMUNICATION; CELL CULTURE; CYTOTOXICITY; GENETICS; HUMAN; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MUROMEGALOVIRUS; T LYMPHOCYTE SUBPOPULATION; VACCINIA; VACCINIA VIRUS; VIROLOGY;

ANIMALS; CALCIUM SIGNALING; CELL COMMUNICATION; CELLS, CULTURED; CYTOTOXICITY, IMMUNOLOGIC; HERPESVIRIDAE INFECTIONS; HUMANS; IMMUNE EVASION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; MUROMEGALOVIRUS; PERFORIN; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, CYTOTOXIC; VACCINIA; VACCINIA VIRUS;

EID: 84958101717     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2016.01.010     Document Type: Article

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