Identification of transcriptome signatures and biomarkers specific for potential developmental toxicants inhibiting human neural crest cell migration

Archives of Toxicology

Volumn 90, Issue 1, 2016, Pages 159-180

  Pallocca, Giorgia ^a   Grinberg, Marianna ^b   Henry, Margit ^c   Frickey, Tancred ^a   Hengstler, Jan G ^b   Waldmann, Tanja ^a   Sachinidis, Agapios ^a   Rahnenführer, Jörg ^b   Leist, Marcel ^a  

^a UNIVERSITY OF KONSTANZ   (Germany)

^b TU DORTMUND UNIVERSITY   (Germany)

^c UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Alternative testing; Developmental toxicity; Neural crest cells; Transcriptome profiling

Indexed keywords

ARSENIC TRIOXIDE; BIOLOGICAL MARKER; FLAME RETARDANT; GELDANAMYCIN; TOXIC SUBSTANCE; TRANSCRIPTOME; TRIADIMEFON; TRICHOSTATIN A; VALPROIC ACID; GENETIC MARKER;

ARTICLE; BIOLOGICAL PHENOMENA AND FUNCTIONS CONCERNING THE ENTIRE ORGANISM; CELL MIGRATION; CONTROLLED STUDY; DEVELOPMENTAL TOXICITY; FOLLOW UP; HUMAN; HUMAN CELL; NEURAL CREST CELL; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TOXICITY ASSAY; ANIMAL TESTING ALTERNATIVE; BIOLOGY; CELL LINE; CELL MOTION; COMPARATIVE STUDY; DATA MINING; DNA MICROARRAY; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC DATABASE; GENETIC MARKER; GENETICS; METABOLISM; NEURAL CREST; NEURAL STEM CELL; PATHOLOGY; PROCEDURES; RISK ASSESSMENT; TIME FACTOR; TOXICITY TESTING;

ANIMAL TESTING ALTERNATIVES; CELL LINE; CELL MOVEMENT; COMPUTATIONAL BIOLOGY; DATA MINING; DATABASES, GENETIC; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC MARKERS; HUMANS; NEURAL CREST; NEURAL STEM CELLS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RISK ASSESSMENT; TIME FACTORS; TOXICITY TESTS;

EID: 84955382107     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-015-1658-7     Document Type: Article

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