Grouping of histone deacetylase inhibitors and other toxicants disturbing neural crest migration by transcriptional profiling

NeuroToxicology

Volumn 50, Issue , 2015, Pages 56-70

  Dreser, Nadine ^a   Zimmer, Bastian ^b   Dietz, Christian ^a   Sügis, Elena ^c   Pallocca, Giorgia ^a   Nyffeler, Johanna ^a   Meisig, Johannes ^d,e   Blüthgen, Nils ^d,e   Berthold, Michael R ^a   Waldmann, Tanja ^a   Leist, Marcel ^a  

^a UNIVERSITY OF KONSTANZ   (Germany)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c UNIVERSITY OF TARTU   (Estonia)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^e HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Chemical grouping; Gene expression; HDAC inhibitors; Metals; Migration; Neural crest; Pathways of toxicity; PCBs; Pesticides; Read across; Toxicology

Indexed keywords

ARSENIC TRIOXIDE; CADMIUM CHLORIDE; HISTONE DEACETYLASE INHIBITOR; LEAD ACETATE; METHYLMERCURY; POLYCHLORINATED BIPHENYL DERIVATIVE; ROTENONE; THIOMERSAL; TOXIC SUBSTANCE; TRIADIMEFON; TRIADIMENOL; TRICHOSTATIN A; TUBACIN; VALPROIC ACID; VORINOSTAT; DANGEROUS GOODS; GREEN FLUORESCENT PROTEIN; HYDROXAMIC ACID;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL MIGRATION; CLUSTER ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; DISCRIMINANT ANALYSIS; EMBRYONIC STEM CELL; FIBROBLAST; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MOUSE; NEURAL CREST CELL; NEUROTOXICITY; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; CELL MOTION; DANGEROUS GOODS; DNA MICROARRAY; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENETIC TRANSFECTION; GENETICS; HUMAN EMBRYONIC STEM CELL; METABOLISM; NEURAL CREST; PHARMACOLOGY; TIME FACTOR; TOXICITY TESTING; TRANSFORMED CELL LINE;

CELL LINE, TRANSFORMED; CELL MOVEMENT; DISCRIMINANT ANALYSIS; GENE EXPRESSION PROFILING; GREEN FLUORESCENT PROTEINS; HAZARDOUS SUBSTANCES; HISTONE DEACETYLASE INHIBITORS; HUMAN EMBRYONIC STEM CELLS; HUMANS; HYDROXAMIC ACIDS; NEURAL CREST; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; TIME FACTORS; TOXICITY TESTS; TRANSCRIPTION, GENETIC; TRANSFECTION; UP-REGULATION;

EID: 84939235734     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2015.07.008     Document Type: Article

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