메뉴 건너뛰기




Volumn 91, Issue 10, 2017, Pages

Oral prion disease pathogenesis is impeded in the specific absence of CXCR5-expressing dendritic cells

Author keywords

Chemokines; Dendritic cells; Gastrointestinal infection; Intestine; Peyer's patches; Prions; Transmissible spongiform encephalopathy

Indexed keywords

CHEMOKINE RECEPTOR CXCR5; CLUSTERIN; COMPLEMENT COMPONENT C3B RECEPTOR; COMPLEMENT COMPONENT C3D RECEPTOR; CXCL13 CHEMOKINE; GLYCOPROTEIN P 15095; BLR1 PROTEIN, MOUSE; CXCL13 PROTEIN, MOUSE; PRION;

EID: 85018341706     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00124-17     Document Type: Article
Times cited : (33)

References (100)
  • 2
    • 0028874995 scopus 로고
    • A cellular isoform of prion protein (PrPc) exists in many non-neuronal tissues of sheep
    • Horiuchi M, Yamazaki N, Ikeda T, Ishiguro N, Shinagawa M. 1995. A cellular isoform of prion protein (PrPc) exists in many non-neuronal tissues of sheep. J Gen Virol 76:2583-2587. https://doi.org/10.1099/ 0022-1317-76-10-2583.
    • (1995) J Gen Virol , vol.76 , pp. 2583-2587
    • Horiuchi, M.1    Yamazaki, N.2    Ikeda, T.3    Ishiguro, N.4    Shinagawa, M.5
  • 4
    • 0038618854 scopus 로고    scopus 로고
    • Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility
    • Mabbott NA, Young J, McConnell I, Bruce ME. 2003. Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility. J Virol 77: 6845-6854. https://doi.org/10.1128/JVI.77.12.6845-6854.2003.
    • (2003) J Virol , vol.77 , pp. 6845-6854
    • Mabbott, N.A.1    Young, J.2    McConnell, I.3    Bruce, M.E.4
  • 5
    • 33947228815 scopus 로고    scopus 로고
    • Role of the GALT in scrapie agent neuroinvasion from the intestine
    • Glaysher BR, Mabbott NA. 2007. Role of the GALT in scrapie agent neuroinvasion from the intestine. J Immunol 178:3757-3766. https:// doi.org/10.4049/jimmunol.178.6.3757.
    • (2007) J Immunol , vol.178 , pp. 3757-3766
    • Glaysher, B.R.1    Mabbott, N.A.2
  • 6
    • 84940526670 scopus 로고    scopus 로고
    • The gut-associated lymphoid tissues in the small intestine, not the large intestine, play a major role in oral prion disease pathogenesis
    • Donaldson DS, Else KJ, Mabbott NA. 2015. The gut-associated lymphoid tissues in the small intestine, not the large intestine, play a major role in oral prion disease pathogenesis. J Virol 15:9532-9547. https://doi .org/10.1128/JVI.01544-15.
    • (2015) J Virol , vol.15 , pp. 9532-9547
    • Donaldson, D.S.1    Else, K.J.2    Mabbott, N.A.3
  • 7
    • 0034536342 scopus 로고    scopus 로고
    • Early accumulation of PrPSc in gut-associated lymphoid and nervous tissues of susceptible sheep from a Romanov flock with natural scrapie
    • Andreoletti O, Berthon P, Marc D, Sarradin P, Grosclaude J, van Keulen L, Schelcher F, Elsen J-M, Lantier F. 2000. Early accumulation of PrPSc in gut-associated lymphoid and nervous tissues of susceptible sheep from a Romanov flock with natural scrapie. J Gen Virol 81:3115-3126. https:// doi.org/10.1099/0022-1317-81-12-3115.
    • (2000) J Gen Virol , vol.81 , pp. 3115-3126
    • Andreoletti, O.1    Berthon, P.2    Marc, D.3    Sarradin, P.4    Grosclaude, J.5    van Keulen, L.6    Schelcher, F.7    Elsen, J.-M.8    Lantier, F.9
  • 8
    • 0032883356 scopus 로고    scopus 로고
    • Oral transmission and early lymphoid tropism of chronic wasting disease PrPres in mule deer fawns (Odocoileus hemionus)
    • Sigurdson CJ, Williams ES, Miller MW, Spraker TR, O'Rourke KI, Hoover EA. 1999. Oral transmission and early lymphoid tropism of chronic wasting disease PrPres in mule deer fawns (Odocoileus hemionus). J Gen Virol 80:2757-2764. https://doi.org/10.1099/0022-1317-80-10-2757.
    • (1999) J Gen Virol , vol.80 , pp. 2757-2764
    • Sigurdson, C.J.1    Williams, E.S.2    Miller, M.W.3    Spraker, T.R.4    O'Rourke, K.I.5    Hoover, E.A.6
  • 10
    • 0033987269 scopus 로고    scopus 로고
    • Early accumulation of pathological PrP in the enteric nervous system and gut-associated lymphoid tissue of hamsters orally infected with scrapie
    • Beekes M, McBride PA. 2000. Early accumulation of pathological PrP in the enteric nervous system and gut-associated lymphoid tissue of hamsters orally infected with scrapie. Neurosci Lett 278:181-184. https://doi.org/10.1016/S0304-3940(99)00934-9.
    • (2000) Neurosci Lett , vol.278 , pp. 181-184
    • Beekes, M.1    McBride, P.A.2
  • 11
    • 0034856845 scopus 로고    scopus 로고
    • Early spread of scrapie from the gastrointestinal tract to the central nervous system involves autonomic fibers of the splanchnic and vagus nerves
    • McBride PA, Schulz-Shaeffer WJ, Donaldson M, Bruce M, Diringer H, Kretzschmar HA, Beekes M. 2001. Early spread of scrapie from the gastrointestinal tract to the central nervous system involves autonomic fibers of the splanchnic and vagus nerves. J Virol 75:9320-9327. https:// doi.org/10.1128/JVI.75.19.9320-9327.2001.
    • (2001) J Virol , vol.75 , pp. 9320-9327
    • McBride, P.A.1    Schulz-Shaeffer, W.J.2    Donaldson, M.3    Bruce, M.4    Diringer, H.5    Kretzschmar, H.A.6    Beekes, M.7
  • 12
    • 0034891027 scopus 로고    scopus 로고
    • Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion
    • Glatzel M, Heppner FL, Albers KM, Aguzzi A. 2001. Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasion. Neuron 31:25-34. https://doi.org/10.1016/S0896-6273(01)00331-2.
    • (2001) Neuron , vol.31 , pp. 25-34
    • Glatzel, M.1    Heppner, F.L.2    Albers, K.M.3    Aguzzi, A.4
  • 13
    • 84949955594 scopus 로고    scopus 로고
    • The good, the bad, and the ugly of dendritic cells during prion disease
    • Mabbott NA, Bradford BM. 2015. The good, the bad, and the ugly of dendritic cells during prion disease. J Immunol Res 2015:168574. https://doi.org/10.1155/2015/168574.
    • (2015) J Immunol Res , vol.2015
    • Mabbott, N.A.1    Bradford, B.M.2
  • 18
    • 80052541140 scopus 로고    scopus 로고
    • Expression of mesenchyme-specific gene signatures by follicular dendritic cells: insights from the meta-analysis of microarray data from multiple mouse cell populations
    • Mabbott NA, Bailie JK, Kobayashi A, Donaldson DS, Ohmori H, Yoon S-O, Freedman AS, Freeman TC, Summers KM. 2011. Expression of mesenchyme-specific gene signatures by follicular dendritic cells: insights from the meta-analysis of microarray data from multiple mouse cell populations. Immunology 133:482-498. https://doi.org/10.1111/j .1365-2567.2011.03461.x.
    • (2011) Immunology , vol.133 , pp. 482-498
    • Mabbott, N.A.1    Bailie, J.K.2    Kobayashi, A.3    Donaldson, D.S.4    Ohmori, H.5    Yoon, S.-O.6    Freedman, A.S.7    Freeman, T.C.8    Summers, K.M.9
  • 19
    • 0032145432 scopus 로고    scopus 로고
    • Dendritic cells interact directly with Naive B lymphocytes to transfer antigen and initiate class switching in a primary T-dependent response
    • Wykes M, Pombo A, Jenkins C, MacPherson GG. 1998. Dendritic cells interact directly with Naive B lymphocytes to transfer antigen and initiate class switching in a primary T-dependent response. J Immunol 161:1313-1319.
    • (1998) J Immunol , vol.161 , pp. 1313-1319
    • Wykes, M.1    Pombo, A.2    Jenkins, C.3    MacPherson, G.G.4
  • 21
    • 0035253347 scopus 로고    scopus 로고
    • Infection of human dendritic cells by dengue virus causes cell maturation and cytokine production
    • Ho L-J, Wang J-J, Shaio M-F, Kao C-L, Chang D-M, Han S-W, Lai J-H. 2001. Infection of human dendritic cells by dengue virus causes cell maturation and cytokine production. J Immunol 166:1499-1506. https://doi.org/10.4049/jimmunol.166.3.1499.
    • (2001) J Immunol , vol.166 , pp. 1499-1506
    • Ho, L.-J.1    Wang, J.-J.2    Shaio, M.-F.3    Kao, C.-L.4    Chang, D.-M.5    Han, S.-W.6    Lai, J.-H.7
  • 23
    • 82755189241 scopus 로고    scopus 로고
    • Lung CD103+ dendritic cells efficiently transport influenza virus to the lymph node and load viral antigen onto MHC class I for presentation to CD8 T cells
    • Ho AW, Prabhu N, Betts RJ, Ge MQ, Dai X, Hutchinson PE, Lew FC, Wong KL, Hanson BJ, Macary PA, Kemeny DM. 2011. Lung CD103+ dendritic cells efficiently transport influenza virus to the lymph node and load viral antigen onto MHC class I for presentation to CD8 T cells. J Immunol 187:6011-6021. https://doi.org/10.4049/jimmunol.1100987.
    • (2011) J Immunol , vol.187 , pp. 6011-6021
    • Ho, A.W.1    Prabhu, N.2    Betts, R.J.3    Ge, M.Q.4    Dai, X.5    Hutchinson, P.E.6    Lew, F.C.7    Wong, K.L.8    Hanson, B.J.9    Macary, P.A.10    Kemeny, D.M.11
  • 24
    • 38849196274 scopus 로고    scopus 로고
    • In vivo depletion of CD11c+ cells impairs scrapie agent neuroinvasion from the intestine
    • Raymond CR, Aucouturier P, Mabbott NA. 2007. In vivo depletion of CD11c+ cells impairs scrapie agent neuroinvasion from the intestine. J Immunol 179:7758-7766. https://doi.org/10.4049/jimmunol .179.11.7758.
    • (2007) J Immunol , vol.179 , pp. 7758-7766
    • Raymond, C.R.1    Aucouturier, P.2    Mabbott, N.A.3
  • 25
    • 50149085067 scopus 로고    scopus 로고
    • Temporary depletion of CD11c+ dendritic cells delays lymphoinvasion after intraperitoneal scrapie infection
    • Cordier-Dirikoc S, Chabry J. 2008. Temporary depletion of CD11c+ dendritic cells delays lymphoinvasion after intraperitoneal scrapie infection. J Virol 82:8933-8936. https://doi.org/10.1128/JVI.02440-07.
    • (2008) J Virol , vol.82 , pp. 8933-8936
    • Cordier-Dirikoc, S.1    Chabry, J.2
  • 26
    • 34247646891 scopus 로고    scopus 로고
    • Role of the CD8+ dendritic cell subset in transmission of prions
    • Sethi S, Kerksiek KM, Brocker T, Kretzschmar H. 2007. Role of the CD8+ dendritic cell subset in transmission of prions. J Virol 81:4877-4880. https://doi.org/10.1128/JVI.02345-06.
    • (2007) J Virol , vol.81 , pp. 4877-4880
    • Sethi, S.1    Kerksiek, K.M.2    Brocker, T.3    Kretzschmar, H.4
  • 27
    • 84860892468 scopus 로고    scopus 로고
    • Determining the role of mononuclear phagocytes in prion neuroinvasion from the skin
    • Wathne GJ, Kissenpfennig A, Malissen B, Zurzolo C, Mabbott NA. 2012. Determining the role of mononuclear phagocytes in prion neuroinvasion from the skin. J Leukoc Biol 91:817-828. https://doi.org/10.1189/ jlb.1211633.
    • (2012) J Leukoc Biol , vol.91 , pp. 817-828
    • Wathne, G.J.1    Kissenpfennig, A.2    Malissen, B.3    Zurzolo, C.4    Mabbott, N.A.5
  • 28
    • 0035053039 scopus 로고    scopus 로고
    • Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie
    • Mabbott NA, Bruce ME, Botto M, Walport MJ, Pepys MB. 2001. Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie. Nat Med 7:485-487. https:// doi.org/10.1038/86562.
    • (2001) Nat Med , vol.7 , pp. 485-487
    • Mabbott, N.A.1    Bruce, M.E.2    Botto, M.3    Walport, M.J.4    Pepys, M.B.5
  • 30
    • 0032545987 scopus 로고    scopus 로고
    • A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1
    • Gunn MD, Ngo VN, Ansel KM, Ekland EH, Cyster JG, Williams LT. 1998. A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1. Nature 391:799-803. https://doi.org/10 .1038/35876.
    • (1998) Nature , vol.391 , pp. 799-803
    • Gunn, M.D.1    Ngo, V.N.2    Ansel, K.M.3    Ekland, E.H.4    Cyster, J.G.5    Williams, L.T.6
  • 32
    • 0037093993 scopus 로고    scopus 로고
    • B cells control the migration of a subset of dendritic cells into B cell follicles via CXC chemokine ligand 13 in a lymphotoxin-dependent fashion
    • Yu P, Wang Y, Chin RK, Martinez-Pomares L, Gordon S, Kosco-Vilbois MH, Cyster J, Fu Y-X. 2002. B cells control the migration of a subset of dendritic cells into B cell follicles via CXC chemokine ligand 13 in a lymphotoxin-dependent fashion. J Immunol 168:5117-5123. https:// doi.org/10.4049/jimmunol.168.10.5117.
    • (2002) J Immunol , vol.168 , pp. 5117-5123
    • Yu, P.1    Wang, Y.2    Chin, R.K.3    Martinez-Pomares, L.4    Gordon, S.5    Kosco-Vilbois, M.H.6    Cyster, J.7    Fu, Y.-X.8
  • 33
    • 0033788786 scopus 로고    scopus 로고
    • A migratory population of skin-derived dendritic cells expresses CXCR5, responds to B lymphocyte chemoattractant in vitro, and colocalizes to B cell zones in lymph nodes in vivo
    • Saeki H, Wu M, Olasz E, Hwang ST. 2000. A migratory population of skin-derived dendritic cells expresses CXCR5, responds to B lymphocyte chemoattractant in vitro, and colocalizes to B cell zones in lymph nodes in vivo. Eur J Immunol 30:2808-2814. https://doi.org/10.1002/1521-4141(200010)30:10-2808::AID-IMMU2808-3.0.CO;2-K.
    • (2000) Eur J Immunol , vol.30 , pp. 2808-2814
    • Saeki, H.1    Wu, M.2    Olasz, E.3    Hwang, S.T.4
  • 34
    • 84862592738 scopus 로고    scopus 로고
    • Regulation of T(H)2 development by CXCR5+ dendritic cells and lymphotoxin-expressing B cells
    • Leon B, Ballesteros-Tato A, Browning JL, Dunn R, Randall TD, Lund FE. 2012. Regulation of T(H)2 development by CXCR5+ dendritic cells and lymphotoxin-expressing B cells. Nat Immunol 13:681-690. https://doi .org/10.1038/ni.2309.
    • (2012) Nat Immunol , vol.13 , pp. 681-690
    • Leon, B.1    Ballesteros-Tato, A.2    Browning, J.L.3    Dunn, R.4    Randall, T.D.5    Lund, F.E.6
  • 35
    • 33645793083 scopus 로고    scopus 로고
    • Alymphoplasia mice are resistant to prion infection via oral route
    • Horiuchi M, Furuoka H, Kitamura N, Shinagawa M. 2006. Alymphoplasia mice are resistant to prion infection via oral route. Jpn J Vet Res 53:149-157.
    • (2006) Jpn J Vet Res , vol.53 , pp. 149-157
    • Horiuchi, M.1    Furuoka, H.2    Kitamura, N.3    Shinagawa, M.4
  • 36
    • 0030582773 scopus 로고    scopus 로고
    • A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen
    • Förster R, Mattis AE, Kremmer E, Wolf E, Brem G, Lipp M. 1996. A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell 87:1037-1047. https://doi.org/10.1016/S0092-8674(00)81798-5.
    • (1996) Cell , vol.87 , pp. 1037-1047
    • Förster, R.1    Mattis, A.E.2    Kremmer, E.3    Wolf, E.4    Brem, G.5    Lipp, M.6
  • 38
    • 34447275920 scopus 로고    scopus 로고
    • Notch-RBP-J signaling controls the homeostasis of CD8+ dendritic cells in the spleen
    • Caton ML, Smith-Raska MR, Reizis B. 2007. Notch-RBP-J signaling controls the homeostasis of CD8+ dendritic cells in the spleen. J Exp Med 204:1653-1664. https://doi.org/10.1084/jem.20062648.
    • (2007) J Exp Med , vol.204 , pp. 1653-1664
    • Caton, M.L.1    Smith-Raska, M.R.2    Reizis, B.3
  • 41
    • 33646917482 scopus 로고    scopus 로고
    • Anatomy and nomenclature of murine lymph nodes: descriptive study and nomenclatory standardization in BALB/cAnNCrl mice
    • Van den Broek W, Derore A, Simoens P. 2006. Anatomy and nomenclature of murine lymph nodes: descriptive study and nomenclatory standardization in BALB/cAnNCrl mice. J Immunol Met 312:12-19. https://doi.org/10.1016/j.jim.2006.01.022.
    • (2006) J Immunol Met , vol.312 , pp. 12-19
    • Van den Broek, W.1    Derore, A.2    Simoens, P.3
  • 42
    • 84855282475 scopus 로고    scopus 로고
    • Follicular dendritic cell-specific prion protein (PrPC) expression alone is sufficient to sustain prion infection in the spleen
    • McCulloch L, Brown KL, Bradford BM, Hopkins J, Bailey M, Rajewsky K, Manson JC, Mabbott NA. 2011. Follicular dendritic cell-specific prion protein (PrPC) expression alone is sufficient to sustain prion infection in the spleen. PLoS Pathog 7:e1002402. https://doi.org/10.1371/journal .ppat.1002402.
    • (2011) PLoS Pathog , vol.7
    • McCulloch, L.1    Brown, K.L.2    Bradford, B.M.3    Hopkins, J.4    Bailey, M.5    Rajewsky, K.6    Manson, J.C.7    Mabbott, N.A.8
  • 45
    • 85007557358 scopus 로고    scopus 로고
    • Increased abundance of M cells in the gut epithelium dramatically enhances oral prion disease susceptibility
    • Donaldson DS, Sehgal A, Rios D, Williams IR, Mabbott NA. 2016. Increased abundance of M cells in the gut epithelium dramatically enhances oral prion disease susceptibility. PLoS Pathog 12:e1006075. https://doi.org/10.1371/journal.ppat.1006075.
    • (2016) PLoS Pathog , vol.12
    • Donaldson, D.S.1    Sehgal, A.2    Rios, D.3    Williams, I.R.4    Mabbott, N.A.5
  • 46
    • 0027074778 scopus 로고
    • PrP protein is associated with follicular dendritic cells of spleens and lymph nodes in uninfected and scrapie-infected mice
    • McBride P, Eikelenboom P, Kraal G, Fraser H, Bruce ME. 1992. PrP protein is associated with follicular dendritic cells of spleens and lymph nodes in uninfected and scrapie-infected mice. J Pathol 168:413-418. https://doi.org/10.1002/path.1711680412.
    • (1992) J Pathol , vol.168 , pp. 413-418
    • McBride, P.1    Eikelenboom, P.2    Kraal, G.3    Fraser, H.4    Bruce, M.E.5
  • 47
    • 0033930508 scopus 로고    scopus 로고
    • Temporary inactivation of follicular dendritic cells delays neuroinvasion of scrapie
    • Mabbott NA, Mackay F, Minns F, Bruce ME. 2000. Temporary inactivation of follicular dendritic cells delays neuroinvasion of scrapie. Nat Med 6:719-720. https://doi.org/10.1038/77401.
    • (2000) Nat Med , vol.6 , pp. 719-720
    • Mabbott, N.A.1    Mackay, F.2    Minns, F.3    Bruce, M.E.4
  • 50
    • 84861110366 scopus 로고    scopus 로고
    • B cell-specific S1PR1 deficiency blocks prion dissemination between secondary lymphoid organs
    • Mok SW, Proia RL, Brinkmann V, Mabbott NA. 2012. B cell-specific S1PR1 deficiency blocks prion dissemination between secondary lymphoid organs. J Immunol 188:5032-5040. https://doi.org/10.4049/ jimmunol.1200349.
    • (2012) J Immunol , vol.188 , pp. 5032-5040
    • Mok, S.W.1    Proia, R.L.2    Brinkmann, V.3    Mabbott, N.A.4
  • 51
    • 84880669087 scopus 로고    scopus 로고
    • CXCR4 promotes B cell egress from Peyer's patches
    • Schmidt TH, Bannard O, Gray EE, Cyster JG. 2013. CXCR4 promotes B cell egress from Peyer's patches. J Exp Med 210:1099-1107. https://doi .org/10.1084/jem.20122574.
    • (2013) J Exp Med , vol.210 , pp. 1099-1107
    • Schmidt, T.H.1    Bannard, O.2    Gray, E.E.3    Cyster, J.G.4
  • 54
    • 84956749281 scopus 로고    scopus 로고
    • M cellderived vesicles suggest a unique pathway for transepithelial antigen delivery
    • Sakhon OS, Ross B, Gusti V, Pham AJ, Vu K, lo DD. 2015. M cellderived vesicles suggest a unique pathway for transepithelial antigen delivery. Tissues Barriers 3:e1004975. https://doi.org/10.1080/ 21688370.2015.1004975.
    • (2015) Tissues Barriers , vol.3
    • Sakhon, O.S.1    Ross, B.2    Gusti, V.3    Pham, A.J.4    Vu, K.5    lo, D.D.6
  • 58
    • 77957923715 scopus 로고    scopus 로고
    • Characterization of the role of dendritic cells in prion transfer to primary neurons
    • Langevin C, Gousset K, Costanzo M, Richard-Le Goff O, Zurzolo C. 2010. Characterization of the role of dendritic cells in prion transfer to primary neurons. Biochem J 431:189-198. https://doi.org/10.1042/ BJ20100698.
    • (2010) Biochem J , vol.431 , pp. 189-198
    • Langevin, C.1    Gousset, K.2    Costanzo, M.3    Richard-Le Goff, O.4    Zurzolo, C.5
  • 59
    • 0034678392 scopus 로고    scopus 로고
    • Localization of distinct Peyer's patch dendritic cell subsets and their recruitment by chemokines macrophage inflammatory protein (MIP)-3, MIP-3+, and secondary lymphoid organ chemokine
    • Iwasaki A, Kelsalla BA. 2000. Localization of distinct Peyer's patch dendritic cell subsets and their recruitment by chemokines macrophage inflammatory protein (MIP)-3, MIP-3+, and secondary lymphoid organ chemokine. J Exp Med 191:1381-1394. https://doi.org/10.1084/ jem.191.8.1381.
    • (2000) J Exp Med , vol.191 , pp. 1381-1394
    • Iwasaki, A.1    Kelsalla, B.A.2
  • 62
    • 0035895051 scopus 로고    scopus 로고
    • The normal cellular prion protein is strongly expressed by myeloid dendritic cells
    • Burthem J, Urban B, Pain A, Roberts DJ. 2001. The normal cellular prion protein is strongly expressed by myeloid dendritic cells. Blood 98: 3733-3738. https://doi.org/10.1182/blood.V98.13.3733.
    • (2001) Blood , vol.98 , pp. 3733-3738
    • Burthem, J.1    Urban, B.2    Pain, A.3    Roberts, D.J.4
  • 63
    • 51149089346 scopus 로고    scopus 로고
    • Expression profiles of prion and doppel proteins and of their receptors in mouse splenocytes
    • Cordier-Dirikoc S, Zsürger N, Cazareth J, Ménard B, Chabry J. 2008. Expression profiles of prion and doppel proteins and of their receptors in mouse splenocytes. Eur J Immunol 38:1-11. https://doi.org/10.1002/ eji.200790062.
    • (2008) Eur J Immunol , vol.38 , pp. 1-11
    • Cordier-Dirikoc, S.1    Zsürger, N.2    Cazareth, J.3    Ménard, B.4    Chabry, J.5
  • 66
    • 3242768388 scopus 로고    scopus 로고
    • Scrapie transmission following exposure through the skin is dependent on follicular dendritic cells in lymphoid tissues
    • Mohan J, Brown KL, Farquhar CF, Bruce ME, Mabbott NA. 2004. Scrapie transmission following exposure through the skin is dependent on follicular dendritic cells in lymphoid tissues. J Dermatol Sci 35:101-111. https://doi.org/10.1016/j.jdermsci.2004.05.005.
    • (2004) J Dermatol Sci , vol.35 , pp. 101-111
    • Mohan, J.1    Brown, K.L.2    Farquhar, C.F.3    Bruce, M.E.4    Mabbott, N.A.5
  • 67
    • 78049298674 scopus 로고    scopus 로고
    • Prion replication in the hematopoietic compartment is not required for neuroinvasion in scrapie mouse model
    • Loeuillet C, Lemaire-Vielle C, Naquet P, Cesbron-Delauw M-F, Gagnon J, Cesbron J-Y. 2010. Prion replication in the hematopoietic compartment is not required for neuroinvasion in scrapie mouse model. PLoS One 5:e13166. https://doi.org/10.1371/journal.pone.0013166.
    • (2010) PLoS One , vol.5
    • Loeuillet, C.1    Lemaire-Vielle, C.2    Naquet, P.3    Cesbron-Delauw, M.-F.4    Gagnon, J.5    Cesbron, J.-Y.6
  • 72
    • 63149177593 scopus 로고    scopus 로고
    • Scrapie pathogenesis: the role of complement C1q in scrapie agent uptake by conventional dendritic cells
    • Flores-Lagnarica A, Sebti Y, Mitchell DA, Sim RB, MacPherson GG. 2009. Scrapie pathogenesis: the role of complement C1q in scrapie agent uptake by conventional dendritic cells. J Immunol 182:1305-1313. https://doi.org/10.4049/jimmunol.182.3.1305.
    • (2009) J Immunol , vol.182 , pp. 1305-1313
    • Flores-Lagnarica, A.1    Sebti, Y.2    Mitchell, D.A.3    Sim, R.B.4    MacPherson, G.G.5
  • 74
    • 84981352016 scopus 로고    scopus 로고
    • Prion pathogenesis is unaltered following down-regulation of SIGN-R1
    • Bradford BM, Brown KL, Mabbott NA. 2016. Prion pathogenesis is unaltered following down-regulation of SIGN-R1. Virology 497: 337-345. https://doi.org/10.1016/j.virol.2016.08.005.
    • (2016) Virology , vol.497 , pp. 337-345
    • Bradford, B.M.1    Brown, K.L.2    Mabbott, N.A.3
  • 75
    • 34548044827 scopus 로고    scopus 로고
    • Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells
    • Phan TG, Grigorova I, Okada T, Cyster JG. 2007. Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells. Nat Immunol 8:992-1000. https://doi.org/10.1038/ ni1494.
    • (2007) Nat Immunol , vol.8 , pp. 992-1000
    • Phan, T.G.1    Grigorova, I.2    Okada, T.3    Cyster, J.G.4
  • 76
    • 34447623566 scopus 로고    scopus 로고
    • B cells acquire particulate antigen in a macrophage-rich area at the boundary between the follicle and the subcapsular sinus of the lymph node
    • Carrasco YR, Batista FD. 2007. B cells acquire particulate antigen in a macrophage-rich area at the boundary between the follicle and the subcapsular sinus of the lymph node. Immunity 27:1-12. https://doi .org/10.1016/j.immuni.2007.07.003.
    • (2007) Immunity , vol.27 , pp. 1-12
    • Carrasco, Y.R.1    Batista, F.D.2
  • 77
    • 67649221652 scopus 로고    scopus 로고
    • Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation
    • Phan TG, Green JA, Gray EE, Xu Y, Cyster JG. 2009. Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation. Nat Immunol 10:786-793. https://doi.org/ 10.1038/ni.1745.
    • (2009) Nat Immunol , vol.10 , pp. 786-793
    • Phan, T.G.1    Green, J.A.2    Gray, E.E.3    Xu, Y.4    Cyster, J.G.5
  • 78
    • 37349013401 scopus 로고    scopus 로고
    • Follicular shuttling of marginal zone B cells facilitates antigen transport
    • Cinamon G, Zachariah MA, Lam OM, Foss FW Jr, Cyster JG. 2008. Follicular shuttling of marginal zone B cells facilitates antigen transport. Nat Immunol 9:54-62. https://doi.org/10.1038/ni1542.
    • (2008) Nat Immunol , vol.9 , pp. 54-62
    • Cinamon, G.1    Zachariah, M.A.2    Lam, O.M.3    Foss, F.W.4    Cyster, J.G.5
  • 81
    • 84939440707 scopus 로고    scopus 로고
    • Prion aggregates transfer through tunneling nanotubes in endocytic vesicles
    • Zhu S, Victoria GS, Marzo L, Ghosh R, Zurzolo C. 2015. Prion aggregates transfer through tunneling nanotubes in endocytic vesicles. Prion 9:125-135. https://doi.org/10.1080/19336896.2015.1025189.
    • (2015) Prion , vol.9 , pp. 125-135
    • Zhu, S.1    Victoria, G.S.2    Marzo, L.3    Ghosh, R.4    Zurzolo, C.5
  • 82
    • 84870888358 scopus 로고    scopus 로고
    • Characterisation of PrPSc transmission from immune cells to neuronal cells
    • Tanaka Y, Sadaike T, Inoshima Y, Ishiguro N. 2012. Characterisation of PrPSc transmission from immune cells to neuronal cells. Cell Immunol 279:145-150. https://doi.org/10.1016/j.cellimm.2012.11.007.
    • (2012) Cell Immunol , vol.279 , pp. 145-150
    • Tanaka, Y.1    Sadaike, T.2    Inoshima, Y.3    Ishiguro, N.4
  • 84
    • 29944444357 scopus 로고    scopus 로고
    • Role of lymph-borne cells in the early stages of scrapie agent dissemination from the skin
    • Gossner A, Hunter N, Hopkins J. 2005. Role of lymph-borne cells in the early stages of scrapie agent dissemination from the skin. Vet Immunol Immunopathol 109:267-278. https://doi.org/10.1016/j.vetimm.2005.08 .021.
    • (2005) Vet Immunol Immunopathol , vol.109 , pp. 267-278
    • Gossner, A.1    Hunter, N.2    Hopkins, J.3
  • 85
    • 0024580902 scopus 로고
    • Pathogenesis of scrapie in mice after intragastric infection
    • Kimberlin RH, Walker CA. 1989. Pathogenesis of scrapie in mice after intragastric infection. Virus Res 12:213-220. https://doi.org/10.1016/ 0168-1702(89)90040-3.
    • (1989) Virus Res , vol.12 , pp. 213-220
    • Kimberlin, R.H.1    Walker, C.A.2
  • 86
    • 80053277573 scopus 로고    scopus 로고
    • Defining the anatomical localisation of subsets of the murine mononuclear phagocyte system using integrin alpha X (Itgax, CD11c) and colony stimulating factor 1 receptor (Csf1r, CD115) expression fails to discriminate dendritic cells from macrophages
    • Bradford BM, Sester D, Hume DA, Mabbott NA. 2011. Defining the anatomical localisation of subsets of the murine mononuclear phagocyte system using integrin alpha X (Itgax, CD11c) and colony stimulating factor 1 receptor (Csf1r, CD115) expression fails to discriminate dendritic cells from macrophages. Immunobiology 216:1228-1237. https://doi.org/10.1016/j.imbio.2011.08.006.
    • (2011) Immunobiology , vol.216 , pp. 1228-1237
    • Bradford, B.M.1    Sester, D.2    Hume, D.A.3    Mabbott, N.A.4
  • 87
    • 84874038349 scopus 로고    scopus 로고
    • Can DCs be distinguished from macrophages by molecular signatures
    • Hume DA, Mabbott N, Raza S, Freeman TC. 2013. Can DCs be distinguished from macrophages by molecular signatures. Nat Immunol 14:187-189. https://doi.org/10.1038/ni.2516.
    • (2013) Nat Immunol , vol.14 , pp. 187-189
    • Hume, D.A.1    Mabbott, N.2    Raza, S.3    Freeman, T.C.4
  • 89
  • 93
    • 32044447002 scopus 로고    scopus 로고
    • Transepithelial pathogen uptake into the small intestinal lamina propria
    • Vallon-Eberhard A, Landsman L, Yogev N, Verrier B, Jung S. 2006. Transepithelial pathogen uptake into the small intestinal lamina propria. J Immunol 176:2465-2469. https://doi.org/10.4049/jimmunol.176 .4.2465.
    • (2006) J Immunol , vol.176 , pp. 2465-2469
    • Vallon-Eberhard, A.1    Landsman, L.2    Yogev, N.3    Verrier, B.4    Jung, S.5
  • 95
    • 0033105359 scopus 로고    scopus 로고
    • Cutting Edge: Secondary lymphoid-tissue chemokine (SLC) and CC chemokine receptor 7 (CCR7) participate in the emigration pathway of mature dendritic cells from the skin to regional lymph nodes
    • Saeki H, Moore AM, Brown MJ, Hwang ST. 1999. Cutting Edge: Secondary lymphoid-tissue chemokine (SLC) and CC chemokine receptor 7 (CCR7) participate in the emigration pathway of mature dendritic cells from the skin to regional lymph nodes. J Immunol 162:2472-2475.
    • (1999) J Immunol , vol.162 , pp. 2472-2475
    • Saeki, H.1    Moore, A.M.2    Brown, M.J.3    Hwang, S.T.4
  • 96
    • 77954100854 scopus 로고    scopus 로고
    • The effects of host age on follicular dendritic cell status dramatically impair scrapie agent neuroinvasion in aged mice
    • Brown KL, Wathne GJ, Sales J, Bruce ME, Mabbott NA. 2009. The effects of host age on follicular dendritic cell status dramatically impair scrapie agent neuroinvasion in aged mice. J Immunol 183:5199-5207. https:// doi.org/10.4049/jimmunol.0802695.
    • (2009) J Immunol , vol.183 , pp. 5199-5207
    • Brown, K.L.1    Wathne, G.J.2    Sales, J.3    Bruce, M.E.4    Mabbott, N.A.5
  • 97
    • 0014308027 scopus 로고
    • The sequential development of the brain lesions of scrapie in three strains of mice
    • Fraser H, Dickinson AG. 1968. The sequential development of the brain lesions of scrapie in three strains of mice. J Comp Pathol 78:301-311. https://doi.org/10.1016/0021-9975(68)90006-6.
    • (1968) J Comp Pathol , vol.78 , pp. 301-311
    • Fraser, H.1    Dickinson, A.G.2
  • 98
    • 0024307533 scopus 로고
    • Postmortem immunodiagnosis of scrapie and bovine spongiform encephalopathy
    • Farquhar CF, Somerville RA, Ritchie LA. 1989. Postmortem immunodiagnosis of scrapie and bovine spongiform encephalopathy. J Virol Met 24:215-222. https://doi.org/10.1016/0166-0934(89)90023-2.
    • (1989) J Virol Met , vol.24 , pp. 215-222
    • Farquhar, C.F.1    Somerville, R.A.2    Ritchie, L.A.3
  • 99
    • 23444446424 scopus 로고    scopus 로고
    • Validation of computer-assisted, pixel-based analysis of multiple-colour immunofluorescence histology
    • Inman CF, Rees LEN, Barker E, Haverson K, Stokes CR, Bailey M. 2005. Validation of computer-assisted, pixel-based analysis of multiple-colour immunofluorescence histology. J Immunol Met 302:156-167. https:// doi.org/10.1016/j.jim.2005.05.005.
    • (2005) J Immunol Met , vol.302 , pp. 156-167
    • Inman, C.F.1    Rees, L.E.N.2    Barker, E.3    Haverson, K.4    Stokes, C.R.5    Bailey, M.6
  • 100
    • 34250644988 scopus 로고    scopus 로고
    • Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans
    • Yin S, Pham N, Yu S, Li C, Wong P, Chang B, Kang S-C, Biasini E, Tien P, Harris DA, Sy M-S. 2007. Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans. Proc Natl Acad Sci U S A 104: 7546-7551. https://doi.org/10.1073/pnas.0610827104.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 7546-7551
    • Yin, S.1    Pham, N.2    Yu, S.3    Li, C.4    Wong, P.5    Chang, B.6    Kang, S.-C.7    Biasini, E.8    Tien, P.9    Harris, D.A.10    Sy, M.-S.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.