Lung CD103 + dendritic cells efficiently transport influenza virus to the lymph node and load viral antigen onto MHC class I for presentation to CD8 T cells

Journal of Immunology

Volumn 187, Issue 11, 2011, Pages 6011-6021

  Ho, Adrian W S ^a   Prabhu, Nayana ^a   Betts, Richard John ^a   Ge, Moyar Qing ^a   Dai, Xilei ^b   Hutchinson, Paul Edward ^a   Lew, Fei Chuin ^a   Wong, Kok Loon ^b   Hanson, Brendon John ^c   Macary, Paul A ^a   Kemeny, David Michael ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b AGENCY FOR SCIENCE   (Singapore)

^c DSO NATIONAL LABORATORIES   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; CYTOKINE; FLUORESCENT DYE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROTEIN TAP2; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING 1; UNCLASSIFIED DRUG; VIRUS ANTIGEN; VIRUS PEPTIDE; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; CD11B CD103+ DENDRITIC CELL; CD8+ T LYMPHOCYTE; CELL ACTIVITY; CELL POPULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DISEASE COURSE; IMMUNOREGULATION; INFLUENZA; INFLUENZA VIRUS; LUNG ALVEOLUS CELL; LYMPHOCYTE PROLIFERATION; MEDIASTINUM LYMPH NODE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIRUS CELL INTERACTION;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, CD; ANTIGENS, VIRAL; CD8-POSITIVE T-LYMPHOCYTES; CELL SEPARATION; DENDRITIC CELLS; FLOW CYTOMETRY; HISTOCOMPATIBILITY ANTIGENS CLASS I; INTEGRIN ALPHA CHAINS; LUNG; LYMPH NODES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; ORTHOMYXOVIRIDAE; ORTHOMYXOVIRIDAE INFECTIONS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 82755189241     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1100987     Document Type: Article

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