The paraffin-embedded tissue blot detects PrP(Sc) early in the incubation time in prion diseases

American Journal of Pathology

Volumn 156, Issue 1, 2000, Pages 51-56

  Schulz Schaeffer, Walter J ^a   Tschöke, Stefan ^a   Kranefuss, Nina ^a   Dröse, Wolfgang ^a   Hause Reitner, Dorothea ^a   Giese, Armin ^a   Groschup, Martin H ^b   Kretzschmar, Hans A ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CREUTZFELDT JAKOB DISEASE; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRION DISEASE; PRIORITY JOURNAL; SCRAPIE; WESTERN BLOTTING;

EID: 0033874288     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)64705-0     Document Type: Article

References (14)

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6. Molecular basis of phenotypic variability in sporadic Creutzfeldt-Jakob disease
7. Replication of distinct scrapie prion isolates is region specific in brains of transgenic mice and hamsters
8. Regional mapping of prion proteins in brain
9. Prion diseases
10. A simple and effective method for inactivating virus infectivity in formalin-fixed tissue samples from patients with Creutzfeldt-Jakob disease
11. Mouse polyclonal and monoclonal antibody to scrapie-associated fibril proteins
12. Generation of monoclonal antibodies against human prion proteins in PrP(O/O) mice
13. Abnormal isoform of prion proteins accumulates in the synaptic structures of the central nervous system in patients with Creutzfeldt-Jakob disease
14. Overexpression of nonconvertible PrP(c)Δ114-121 in scrapie-infected mouse neuroblastoma cells leads to trans-dominant inhibition of wild-type PrP(Sc) accumulation