메뉴 건너뛰기




Volumn 71, Issue 7, 2017, Pages 890-895

Nutrient regulation of β-cell function: What do islet cell/animal studies tell us?

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; GLUCOSE; INSULIN; LIPID; REACTIVE OXYGEN METABOLITE;

EID: 85017649268     PISSN: 09543007     EISSN: 14765640     Source Type: Journal    
DOI: 10.1038/ejcn.2017.49     Document Type: Review
Times cited : (11)

References (59)
  • 1
    • 80052360011 scopus 로고    scopus 로고
    • Finally! A human pancreatic ? Cell line
    • Weir GC, Bonner-Weir S. Finally! A human pancreatic ? cell line. J Clin Invest 2011; 121: 3395-3397.
    • (2011) J Clin Invest , vol.121 , pp. 3395-3397
    • Weir, G.C.1    Bonner-Weir, S.2
  • 2
    • 78349238941 scopus 로고    scopus 로고
    • Pancreatic beta cell lines and their applications in diabetes mellitus research
    • Skelin M, Rupnik M, Cencic A. Pancreatic beta cell lines and their applications in diabetes mellitus research. Altex 2010; 27: 105-113.
    • (2010) Altex , vol.27 , pp. 105-113
    • Skelin, M.1    Rupnik, M.2    Cencic, A.3
  • 3
  • 4
    • 84864317126 scopus 로고    scopus 로고
    • Reactive oxygen and nitrogen species generation, antioxidant defenses, and beta-cell function: A critical role for amino acids
    • Newsholme P, Rebelato E, Abdulkader F, Krause M, Carpinelli A, Curi R. Reactive oxygen and nitrogen species generation, antioxidant defenses, and beta-cell function: a critical role for amino acids. J Endocrinol 2012; 214: 11-20.
    • (2012) J Endocrinol , vol.214 , pp. 11-20
    • Newsholme, P.1    Rebelato, E.2    Abdulkader, F.3    Krause, M.4    Carpinelli, A.5    Curi, R.6
  • 5
    • 79959331354 scopus 로고    scopus 로고
    • Development and functional characterization of insulin-releasing human pancreatic beta cell lines produced by electrofusion
    • McCluskey JT, Hamid M, Guo-Parke H, McClenaghan NH, Gomis R, Flatt PR. Development and functional characterization of insulin-releasing human pancreatic beta cell lines produced by electrofusion. J Biol Chem 2011; 286: 21982-21992.
    • (2011) J Biol Chem , vol.286 , pp. 21982-21992
    • McCluskey, J.T.1    Hamid, M.2    Guo-Parke, H.3    McClenaghan, N.H.4    Gomis, R.5    Flatt, P.R.6
  • 6
    • 84890238001 scopus 로고    scopus 로고
    • Cellular responses of novel human pancreatic beta-cell line, 1.1B4 to hyperglycemia
    • Vasu S, McClenaghan NH, McCluskey JT, Flatt PR. Cellular responses of novel human pancreatic beta-cell line, 1.1B4 to hyperglycemia. Islets 2013; 5: 170-177.
    • (2013) Islets , vol.5 , pp. 170-177
    • Vasu, S.1    McClenaghan, N.H.2    McCluskey, J.T.3    Flatt, P.R.4
  • 7
    • 84882264234 scopus 로고    scopus 로고
    • Effects of lipotoxicity on a novel insulin-secreting human pancreatic beta-cell line, 1.1B4
    • Vasu S, McClenaghan NH, McCluskey JT, Flatt PR. Effects of lipotoxicity on a novel insulin-secreting human pancreatic beta-cell line, 1.1B4. Biol Chem 2013; 394: 909-918.
    • (2013) Biol Chem , vol.394 , pp. 909-918
    • Vasu, S.1    McClenaghan, N.H.2    McCluskey, J.T.3    Flatt, P.R.4
  • 8
    • 84885038142 scopus 로고    scopus 로고
    • Mechanisms of toxicity by proinflammatory cytokines in a novel human pancreatic beta cell line, 1.1B4
    • Vasu S, McClenaghan NH, McCluskey JT, Flatt PR. Mechanisms of toxicity by proinflammatory cytokines in a novel human pancreatic beta cell line, 1.1B4. Biochim Biophys Acta 2014; 1840: 136-145.
    • (2014) Biochim Biophys Acta , vol.1840 , pp. 136-145
    • Vasu, S.1    McClenaghan, N.H.2    McCluskey, J.T.3    Flatt, P.R.4
  • 9
    • 80052343967 scopus 로고    scopus 로고
    • A genetically engineered human pancreatic beta cell line exhibiting glucoseinducible insulin secretion
    • Ravassard P, Hazhouz Y, Pechberty S, Bricout-Neveu E, Armanet M, Czernichow P et al. A genetically engineered human pancreatic beta cell line exhibiting glucoseinducible insulin secretion. J Clin Invest 2011; 121: 3589-3597.
    • (2011) J Clin Invest , vol.121 , pp. 3589-3597
    • Ravassard, P.1    Hazhouz, Y.2    Pechberty, S.3    Bricout-Neveu, E.4    Armanet, M.5    Czernichow, P.6
  • 10
    • 84925688215 scopus 로고    scopus 로고
    • Characterization of stimulus-secretion coupling in the human pancreatic EndoCbetaH1 beta cell line
    • Andersson LE, Valtat B, Bagge A, Sharoyko VV, Nicholls DG, Ravassard P et al. Characterization of stimulus-secretion coupling in the human pancreatic EndoCbetaH1 beta cell line. PLoS ONE 2015; 10: e0120879.
    • (2015) PLoS ONE , vol.10 , pp. e0120879
    • Andersson, L.E.1    Valtat, B.2    Bagge, A.3    Sharoyko, V.V.4    Nicholls, D.G.5    Ravassard, P.6
  • 11
    • 84877772971 scopus 로고    scopus 로고
    • Imatinib mesilate-induced phosphatidylinositol 3-kinase signalling and improved survival in insulin-producing cells: Role of Src homology 2-containing inositol 5'-phosphatase interaction with c-Abl
    • Mokhtari D, Al-Amin A, Turpaev K, Li T, Idevall-Hagren O, Li J et al. Imatinib mesilate-induced phosphatidylinositol 3-kinase signalling and improved survival in insulin-producing cells: role of Src homology 2-containing inositol 5'-phosphatase interaction with c-Abl. Diabetologia 2013; 56: 1327-1338.
    • (2013) Diabetologia , vol.56 , pp. 1327-1338
    • Mokhtari, D.1    Al-Amin, A.2    Turpaev, K.3    Li, T.4    Idevall-Hagren, O.5    Li, J.6
  • 14
    • 84951826410 scopus 로고    scopus 로고
    • A human beta cell line with drug inducible excision of immortalizing transgenes
    • Benazra M, Lecomte MJ, Colace C, Muller A, Machado C, Pechberty S et al. A human beta cell line with drug inducible excision of immortalizing transgenes. Mol Metab 2015; 4: 916-925.
    • (2015) Mol Metab , vol.4 , pp. 916-925
    • Benazra, M.1    Lecomte, M.J.2    Colace, C.3    Muller, A.4    MacHado, C.5    Pechberty, S.6
  • 15
    • 84866306491 scopus 로고    scopus 로고
    • Configuration of electrofusion-derived human insulin-secreting cell line as pseudoislets enhances functionality and therapeutic utility
    • Guo-Parke H, McCluskey JT, Kelly C, Hamid M, McClenaghan NH, Flatt PR. Configuration of electrofusion-derived human insulin-secreting cell line as pseudoislets enhances functionality and therapeutic utility. J Endocrinol 2012; 214: 257-265.
    • (2012) J Endocrinol , vol.214 , pp. 257-265
    • Guo-Parke, H.1    McCluskey, J.T.2    Kelly, C.3    Hamid, M.4    McClenaghan, N.H.5    Flatt, P.R.6
  • 16
    • 84941417995 scopus 로고    scopus 로고
    • Pseudoislet formation enhances gene expression, insulin secretion and cytoprotective mechanisms of clonal human insulin-secreting 1.1B4 cells
    • Green AD, Vasu S, McClenaghan NH, Flatt PR. Pseudoislet formation enhances gene expression, insulin secretion and cytoprotective mechanisms of clonal human insulin-secreting 1.1B4 cells. Pflugers Arch 2015; 467: 2219-2228.
    • (2015) Pflugers Arch , vol.467 , pp. 2219-2228
    • Green, A.D.1    Vasu, S.2    McClenaghan, N.H.3    Flatt, P.R.4
  • 17
    • 85022169091 scopus 로고    scopus 로고
    • Aggregation of engineered human beta-cells into pseudoislets: Insulin secretion and gene expression profile in normoxic and hypoxic milieu
    • Lecomte MJ, Pechberty S, Machado C, Da Barroca S, Ravassard P, Scharfmann R et al. Aggregation of engineered human beta-cells into pseudoislets: insulin secretion and gene expression profile in normoxic and hypoxic milieu. Cell Med 2016; 8: 99-112.
    • (2016) Cell Med , vol.8 , pp. 99-112
    • Lecomte, M.J.1    Pechberty, S.2    MacHado, C.3    Da Barroca, S.4    Ravassard, P.5    Scharfmann, R.6
  • 18
    • 84938153225 scopus 로고    scopus 로고
    • Molecular events linking oxidative stress and inflammation to insulin resistance and betacell dysfunction
    • Keane KN, Cruzat VF, Carlessi R, de Bittencourt JrPI, Newsholme P. Molecular events linking oxidative stress and inflammation to insulin resistance and betacell dysfunction. Oxid Med Cell Longev 2015; 2015: 181643.
    • (2015) Oxid Med Cell Longev , vol.2015 , pp. 181643
    • Keane, K.N.1    Cruzat, V.F.2    Carlessi, R.3    De Bittencourt, P.I.4    Newsholme, P.5
  • 19
    • 0014042613 scopus 로고
    • Method for the isolation of intact islets of Langerhans from the rat pancreas
    • Lacy PE, Kostianovsky M. Method for the isolation of intact islets of Langerhans from the rat pancreas. Diabetes 1967; 16: 35-39.
    • (1967) Diabetes , vol.16 , pp. 35-39
    • Lacy, P.E.1    Kostianovsky, M.2
  • 20
    • 0024532672 scopus 로고
    • Automated islet isolation from human pancreas
    • Ricordi C, Lacy PE, Scharp DW. Automated islet isolation from human pancreas. Diabetes 1989; 38(Suppl 1): 140-142.
    • (1989) Diabetes , vol.38 , pp. 140-142
    • Ricordi, C.1    Lacy, P.E.2    Scharp, D.W.3
  • 21
    • 77957070339 scopus 로고    scopus 로고
    • The isolated pancreatic islet as a micro-organ and its transplantation to cure diabetes: Celebrating the legacy of Paul Lacy
    • Misler S. The isolated pancreatic islet as a micro-organ and its transplantation to cure diabetes: celebrating the legacy of Paul Lacy. Islets 2010; 2: 210-224.
    • (2010) Islets , vol.2 , pp. 210-224
    • Misler, S.1
  • 22
    • 77953955152 scopus 로고    scopus 로고
    • Nutrient regulation of insulin secretion and beta-cell functional integrity
    • Newsholme P, Gaudel C, McClenaghan NH. Nutrient regulation of insulin secretion and beta-cell functional integrity. Adv Exp Med Biol 2010; 654: 91-114.
    • (2010) Adv Exp Med Biol , vol.654 , pp. 91-114
    • Newsholme, P.1    Gaudel, C.2    McClenaghan, N.H.3
  • 23
    • 84901627098 scopus 로고    scopus 로고
    • Nutrient regulation of insulin secretion and action
    • Newsholme P, Cruzat V, Arfuso F, Keane K. Nutrient regulation of insulin secretion and action. J Endocrinol 2014; 221: R105-R120.
    • (2014) J Endocrinol , vol.221 , pp. R105-R120
    • Newsholme, P.1    Cruzat, V.2    Arfuso, F.3    Keane, K.4
  • 24
    • 84984911593 scopus 로고    scopus 로고
    • Impact of islet architecture on betacell heterogeneity, plasticity and function
    • Roscioni SS, Migliorini A, Gegg M, Lickert H. Impact of islet architecture on betacell heterogeneity, plasticity and function. Nat Rev Endocrinol 2016; 12: 695-709.
    • (2016) Nat Rev Endocrinol , vol.12 , pp. 695-709
    • Roscioni, S.S.1    Migliorini, A.2    Gegg, M.3    Lickert, H.4
  • 25
    • 0028095283 scopus 로고
    • Physiologic relevance of heterogeneity in the pancreatic beta-cell population
    • Pipeleers D, Kiekens R, Ling Z, Wilikens A, Schuit F. Physiologic relevance of heterogeneity in the pancreatic beta-cell population. Diabetologia 1994; 37(Suppl 2): S57-S64.
    • (1994) Diabetologia , vol.37 , pp. S57-S64
    • Pipeleers, D.1    Kiekens, R.2    Ling, Z.3    Wilikens, A.4    Schuit, F.5
  • 26
    • 0023244741 scopus 로고
    • The biosociology of pancreatic B cells
    • Pipeleers D. The biosociology of pancreatic B cells. Diabetologia 1987; 30: 277-291.
    • (1987) Diabetologia , vol.30 , pp. 277-291
    • Pipeleers, D.1
  • 27
    • 84888371075 scopus 로고    scopus 로고
    • Minireview: Intraislet regulation of insulin secretion in humans
    • Rutter GA, Hodson DJ. Minireview: intraislet regulation of insulin secretion in humans. Mol Endocrinol 2013; 27: 1984-1995.
    • (2013) Mol Endocrinol , vol.27 , pp. 1984-1995
    • Rutter, G.A.1    Hodson, D.J.2
  • 28
    • 84923148964 scopus 로고    scopus 로고
    • Pancreatic beta-cell identity, glucose sensing and the control of insulin secretion
    • Rutter GA, Pullen TJ, Hodson DJ, Martinez-Sanchez A. Pancreatic beta-cell identity, glucose sensing and the control of insulin secretion. Biochem J 2015; 466: 203-218.
    • (2015) Biochem J , vol.466 , pp. 203-218
    • Rutter, G.A.1    Pullen, T.J.2    Hodson, D.J.3    Martinez-Sanchez, A.4
  • 31
    • 79953752183 scopus 로고    scopus 로고
    • Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD-severe combined immunodeficiency (SCID) mice
    • Levitt HE, Cyphert TJ, Pascoe JL, Hollern DA, Abraham N, Lundell RJ et al. Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD-severe combined immunodeficiency (SCID) mice. Diabetologia 2011; 54: 572-582.
    • (2011) Diabetologia , vol.54 , pp. 572-582
    • Levitt, H.E.1    Cyphert, T.J.2    Pascoe, J.L.3    Hollern, D.A.4    Abraham, N.5    Lundell, R.J.6
  • 32
    • 12344323484 scopus 로고    scopus 로고
    • Type 2 diabetes-A matter of beta-cell life and death?
    • Rhodes CJ. Type 2 diabetes-a matter of beta-cell life and death? Science 2005; 307: 380-384.
    • (2005) Science , vol.307 , pp. 380-384
    • Rhodes, C.J.1
  • 33
    • 84862797520 scopus 로고    scopus 로고
    • Glucose-induced beta cell dysfunction in vivo in rats: Link between oxidative stress and endoplasmic reticulum stress
    • Tang C, Koulajian K, Schuiki I, Zhang L, Desai T, Ivovic A et al. Glucose-induced beta cell dysfunction in vivo in rats: link between oxidative stress and endoplasmic reticulum stress. Diabetologia 2012; 55: 1366-1379.
    • (2012) Diabetologia , vol.55 , pp. 1366-1379
    • Tang, C.1    Koulajian, K.2    Schuiki, I.3    Zhang, L.4    Desai, T.5    Ivovic, A.6
  • 34
    • 0036738398 scopus 로고    scopus 로고
    • Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets
    • Maedler K, Sergeev P, Ris F, Oberholzer J, Joller-Jemelka HI, Spinas GA et al. Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets. J Clin Invest 2002; 110: 851-860.
    • (2002) J Clin Invest , vol.110 , pp. 851-860
    • Maedler, K.1    Sergeev, P.2    Ris, F.3    Oberholzer, J.4    Joller-Jemelka, H.I.5    Spinas, G.A.6
  • 35
    • 84940663541 scopus 로고    scopus 로고
    • Diabetogenic milieus induce specific changes in mitochondrial transcriptome and differentiation of human pancreatic islets
    • Brun T, Li N, Jourdain AA, Gaudet P, Duhamel D, Meyer J et al. Diabetogenic milieus induce specific changes in mitochondrial transcriptome and differentiation of human pancreatic islets. Hum Mol Genet 2015; 24: 5270-5284.
    • (2015) Hum Mol Genet , vol.24 , pp. 5270-5284
    • Brun, T.1    Li, N.2    Jourdain, A.A.3    Gaudet, P.4    Duhamel, D.5    Meyer, J.6
  • 36
    • 84865418265 scopus 로고    scopus 로고
    • Carbohydrate response element-binding protein (ChREBP) plays a pivotal role in beta cell glucotoxicity
    • Poungvarin N, Lee JK, Yechoor VK, Li MV, Assavapokee T, Suksaranjit P et al. Carbohydrate response element-binding protein (ChREBP) plays a pivotal role in beta cell glucotoxicity. Diabetologia 2012; 55: 1783-1796.
    • (2012) Diabetologia , vol.55 , pp. 1783-1796
    • Poungvarin, N.1    Lee, J.K.2    Yechoor, V.K.3    Li, M.V.4    Assavapokee, T.5    Suksaranjit, P.6
  • 38
    • 84990212640 scopus 로고    scopus 로고
    • Integrative genomics outlines a biphasic glucose response and a ChREBP-RORgamma axis regulating proliferation in beta cells
    • Schmidt SF, Madsen JG, Frafjord KO, Poulsen L, Salo S, Boergesen M et al. Integrative genomics outlines a biphasic glucose response and a ChREBP-RORgamma axis regulating proliferation in beta cells. Cell Rep 2016; 16: 2359-2372.
    • (2016) Cell Rep , vol.16 , pp. 2359-2372
    • Schmidt, S.F.1    Madsen, J.G.2    Frafjord, K.O.3    Poulsen, L.4    Salo, S.5    Boergesen, M.6
  • 39
    • 33845541249 scopus 로고    scopus 로고
    • Nutrient control of insulin secretion in isolated normal human islets
    • Henquin JC, Dufrane D, Nenquin M. Nutrient control of insulin secretion in isolated normal human islets. Diabetes 2006; 55: 3470-3477.
    • (2006) Diabetes , vol.55 , pp. 3470-3477
    • Henquin, J.C.1    Dufrane, D.2    Nenquin, M.3
  • 40
    • 84994618783 scopus 로고    scopus 로고
    • Dynamics and regulation of insulin secretion in pancreatic islets from normal young children
    • Henquin JC, Nenquin M. Dynamics and regulation of insulin secretion in pancreatic islets from normal young children. PLoS ONE 2016; 11: e0165961.
    • (2016) PLoS ONE , vol.11 , pp. e0165961
    • Henquin, J.C.1    Nenquin, M.2
  • 41
    • 33846267745 scopus 로고    scopus 로고
    • Life and death decisions of the pancreatic beta-cell: The role of fatty acids
    • Newsholme P, Keane D, Welters HJ, Morgan NG. Life and death decisions of the pancreatic beta-cell: the role of fatty acids. Clin Sci 2007; 112: 27-42.
    • (2007) Clin Sci , vol.112 , pp. 27-42
    • Newsholme, P.1    Keane, D.2    Welters, H.J.3    Morgan, N.G.4
  • 43
    • 82455199162 scopus 로고    scopus 로고
    • Two incretin hormones GLP-1 and GIP: Comparison of their actions in insulin secretion and beta cell preservation
    • Yabe D, Seino Y. Two incretin hormones GLP-1 and GIP: comparison of their actions in insulin secretion and beta cell preservation. Prog Biophys Mol Biol 2011; 107: 248-256.
    • (2011) Prog Biophys Mol Biol , vol.107 , pp. 248-256
    • Yabe, D.1    Seino, Y.2
  • 44
    • 84964725797 scopus 로고    scopus 로고
    • An update on the effect of incretin-based therapies on betacell function and mass
    • Chon S, Gautier JF. An update on the effect of incretin-based therapies on betacell function and mass. Diabetes Metab J 2016; 40: 99-114.
    • (2016) Diabetes Metab J , vol.40 , pp. 99-114
    • Chon, S.1    Gautier, J.F.2
  • 46
    • 84904741336 scopus 로고    scopus 로고
    • Cellular communication and heterogeneity in pancreatic islet insulin secretion dynamics
    • Benninger RK, Piston DW. Cellular communication and heterogeneity in pancreatic islet insulin secretion dynamics. Trends Endocrinol Metab 2014; 25: 399-406.
    • (2014) Trends Endocrinol Metab , vol.25 , pp. 399-406
    • Benninger, R.K.1    Piston, D.W.2
  • 47
    • 84940639041 scopus 로고    scopus 로고
    • Distinct differences in the responses of the human pancreatic beta-cell line EndoC-betaH1 and human islets to proinflammatory cytokines
    • Oleson BJ, McGraw JA, Broniowska KA, Annamalai M, Chen J, Bushkofsky JR et al. Distinct differences in the responses of the human pancreatic beta-cell line EndoC-betaH1 and human islets to proinflammatory cytokines. Am J Physiol Regul Integr Comp Physiol 2015; 309: R525-R534.
    • (2015) Am J Physiol Regul Integr Comp Physiol , vol.309 , pp. R525-R534
    • Oleson, B.J.1    McGraw, J.A.2    Broniowska, K.A.3    Annamalai, M.4    Chen, J.5    Bushkofsky, J.R.6
  • 48
    • 24344459011 scopus 로고    scopus 로고
    • Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy
    • Brissova M, Fowler MJ, Nicholson WE, Chu A, Hirshberg B, Harlan DM et al. Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy. J Histochem Cytochem 2005; 53: 1087-1097.
    • (2005) J Histochem Cytochem , vol.53 , pp. 1087-1097
    • Brissova, M.1    Fowler, M.J.2    Nicholson, W.E.3    Chu, A.4    Hirshberg, B.5    Harlan, D.M.6
  • 49
    • 84862236860 scopus 로고    scopus 로고
    • Islet microarchitecture and glucose transporter expression of the pancreas of the marmoset monkey display similarities to the human
    • Plentz RR, Palagani V, Wiedemann A, Diekmann U, Glage S, Naujok O et al. Islet microarchitecture and glucose transporter expression of the pancreas of the marmoset monkey display similarities to the human. Islets 2012; 4: 123-129.
    • (2012) Islets , vol.4 , pp. 123-129
    • Plentz, R.R.1    Palagani, V.2    Wiedemann, A.3    Diekmann, U.4    Glage, S.5    Naujok, O.6
  • 51
    • 0031747501 scopus 로고    scopus 로고
    • A comparative immunohistochemical study of pancreatic islets in laboratory animals (rats, dogs, minipigs, nonhuman primates)
    • Wieczorek G, Pospischil A, Perentes E. A comparative immunohistochemical study of pancreatic islets in laboratory animals (rats, dogs, minipigs, nonhuman primates). Exp Toxicol Pathol 1998; 50: 151-172.
    • (1998) Exp Toxicol Pathol , vol.50 , pp. 151-172
    • Wieczorek, G.1    Pospischil, A.2    Perentes, E.3
  • 52
    • 84944705104 scopus 로고    scopus 로고
    • Structural similarities and differences between the human and the mouse pancreas
    • Dolensek J, Rupnik MS, Stozer A. Structural similarities and differences between the human and the mouse pancreas. Islets 2015; 7: e1024405.
    • (2015) Islets , vol.7 , pp. e1024405
    • Dolensek, J.1    Rupnik, M.S.2    Stozer, A.3
  • 53
    • 51249098505 scopus 로고    scopus 로고
    • Insulin secretion from human beta cells is heterogeneous and dependent on cell-to-cell contacts
    • Wojtusciszyn A, Armanet M, Morel P, Berney T, Bosco D. Insulin secretion from human beta cells is heterogeneous and dependent on cell-to-cell contacts. Diabetologia 2008; 51: 1843-1852.
    • (2008) Diabetologia , vol.51 , pp. 1843-1852
    • Wojtusciszyn, A.1    Armanet, M.2    Morel, P.3    Berney, T.4    Bosco, D.5
  • 57
    • 0029401861 scopus 로고
    • Differences in the expression of heat-shock proteins and antioxidant enzymes between human and rodent pancreatic islets: Implications for the pathogenesis of insulindependent diabetes mellitus
    • Welsh N, Margulis B, Borg LA, Wiklund HJ, Saldeen J, Flodstrom M et al. Differences in the expression of heat-shock proteins and antioxidant enzymes between human and rodent pancreatic islets: implications for the pathogenesis of insulindependent diabetes mellitus. Mol Med 1995; 1: 806-820.
    • (1995) Mol Med , vol.1 , pp. 806-820
    • Welsh, N.1    Margulis, B.2    Borg, L.A.3    Wiklund, H.J.4    Saldeen, J.5    Flodstrom, M.6
  • 58
    • 84930658369 scopus 로고    scopus 로고
    • Species-related differences in the proteome of rat and human pancreatic beta cells
    • Martens GA. Species-related differences in the proteome of rat and human pancreatic beta cells. J Diabetes Res 2015; 2015: 549818.
    • (2015) J Diabetes Res , vol.2015 , pp. 549818
    • Martens, G.A.1
  • 59
    • 84875772087 scopus 로고    scopus 로고
    • Differences in glucose-stimulated insulin secretion in vitro of islets from human, nonhuman primate, and porcine origin
    • Mueller KR, Balamurugan AN, Cline GW, Pongratz RL, Hooper RL, Weegman BP et al. Differences in glucose-stimulated insulin secretion in vitro of islets from human, nonhuman primate, and porcine origin. Xenotransplantation 2013; 20: 75-81.
    • (2013) Xenotransplantation , vol.20 , pp. 75-81
    • Mueller, K.R.1    Balamurugan, A.N.2    Cline, G.W.3    Pongratz, R.L.4    Hooper, R.L.5    Weegman, B.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.