Effects of lipotoxicity on a novel insulin-secreting human pancreatic β-cell line, 1.1B4

Biological Chemistry

Volumn 394, Issue 7, 2013, Pages 909-918

  Vasu, Srividya ^a   McClenaghan, Neville H ^a   McCluskey, Jane T ^a   Flatt, Peter R ^a  

^a UNIVERSITY OF ULSTER   (United Kingdom)

Author keywords

1.1B4; Diabetes; Mechanisms; Palmitate

Indexed keywords

CASPASE 3; CASPASE 7; CATALASE; CHAPERONE; COMPLEMENTARY DNA; COPPER ZINC SUPEROXIDE DISMUTASE; EUKARYOTIC TRANSLATION INITIATION FACTOR 2 ALPHA KINASE 3; FORSKOLIN; GAP JUNCTION PROTEIN; GLUCAGON LIKE PEPTIDE 1; GLUCOKINASE; GLUCOSE; GLUTATHIONE PEROXIDASE 1; HEAT SHOCK 70 KDA PROTEIN 5; HEAT SHOCK PROTEIN; INITIATION FACTOR; INITIATION FACTOR 2ALPHA; INSULIN; KEXIN; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; PALMITIC ACID; PROPROTEIN CONVERTASE 1; PROPROTEIN CONVERTASE 2; PROPROTEIN CONVERTASE SUBTILISIN KEXIN 1; PROPROTEIN CONVERTASE SUBTILISIN KEXIN 2; PROTEIN BCL 2; SUBTILISIN; UNCLASSIFIED DRUG;

APOPTOSIS; AREA UNDER THE CURVE; ARTICLE; CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; ENZYME INDUCTION; GENE EXPRESSION; HUMAN; INSULIN RELEASE; LD 50; LETHAL DOSE; LIMIT OF QUANTITATION; LIPOTOXICITY; LONG TERM EXPOSURE; PANCREAS ISLET BETA CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN ISOLATION; RECEPTOR DOWN REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; THERAPY EFFECT; TREATMENT OUTCOME; WESTERN BLOTTING;

APOPTOSIS; BLOTTING, WESTERN; CELL LINE; CELL SURVIVAL; COMET ASSAY; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION; HUMANS; INSULIN; INSULIN-SECRETING CELLS; PALMITATES; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; STATISTICS, NONPARAMETRIC;

EID: 84882264234     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/hsz-2013-0115     Document Type: Article

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