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Volumn 11, Issue 11, 2016, Pages

Dynamics and Regulation of Insulin Secretion in Pancreatic Islets from Normal Young Children

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CALCIUM CHLORIDE; CYCLIC AMP; DIAZOXIDE; FORSKOLIN; GLUCOSE; GLUTAMINE; INSULIN; LEUCINE; TOLBUTAMIDE; AMINO ACID;

EID: 84994618783     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0165961     Document Type: Article
Times cited : (25)

References (47)
  • 1
    • 0029021696 scopus 로고
    • Mutations in the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy
    • PMID: 7716548
    • Thomas PM, Cote GJ, Wohllk N, Haddad B, Mathew PM, Aguilar-Bryan L, et al. Mutations in the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy. Science. 1995; 268:426-429. PMID: 7716548
    • (1995) Science , vol.268 , pp. 426-429
    • Thomas, P.M.1    Cote, G.J.2    Wohllk, N.3    Haddad, B.4    Mathew, P.M.5    Aguilar-Bryan, L.6
  • 2
    • 0347359228 scopus 로고    scopus 로고
    • 2004 Hyperinsulinism in infancy: From basic science to clinical disease
    • PMID: 14715916
    • Dunne MJ, Cosgrove KE, Shepherd RM, Aynsley-Green A, Lindley KJ. 2004 Hyperinsulinism in infancy: from basic science to clinical disease. Physiol Rev. 2004; 84:239-275. PMID: 14715916 doi: 10.1152/physrev.00022.2003
    • (2004) Physiol Rev , vol.84 , pp. 239-275
    • Dunne, M.J.1    Cosgrove, K.E.2    Shepherd, R.M.3    Aynsley-Green, A.4    Lindley, K.J.5
  • 3
    • 84960845904 scopus 로고    scopus 로고
    • Perspective on the genetics and diagnosis of congenital hyperinsulinism disorders
    • PMID: 26908106
    • Stanley CA. Perspective on the genetics and diagnosis of congenital hyperinsulinism disorders. J Clin Endocrinol Metab. 2016; 101:815-826. PMID: 26908106 doi: 10.1210/jc.2015-3651
    • (2016) J Clin Endocrinol Metab , vol.101 , pp. 815-826
    • Stanley, C.A.1
  • 4
    • 24144467758 scopus 로고    scopus 로고
    • Activating mutations in Kir6.2 and neonatal diabetes: New clinical syndromes, new scientific insights, and new therapy
    • PMID: 16123337
    • Hattersley AT, Ashcroft FM. Activating mutations in Kir6.2 and neonatal diabetes: new clinical syndromes, new scientific insights, and new therapy. Diabetes. 2005; 54:2503-2513. PMID: 16123337 doi: 10.2337/diabetes.54.9.2503
    • (2005) Diabetes , vol.54 , pp. 2503-2513
    • Hattersley, A.T.1    Ashcroft, F.M.2
  • 5
    • 33746778878 scopus 로고    scopus 로고
    • Activating mutations in the ABCC8 gene in neonatal diabetes mellitus
    • PMID: 16885549
    • Babenko AP, Polak M, Cavé H, Busiah K, Czernichow P, Aguilar-Bryan L, et al. Activating mutations in the ABCC8 gene in neonatal diabetes mellitus. New Engl J Med. 2006; 355:456-466. PMID: 16885549 doi: 10.1056/NEJMoa055068
    • (2006) New Engl J Med , vol.355 , pp. 456-466
    • Babenko, A.P.1    Polak, M.2    Cavé, H.3    Busiah, K.4    Czernichow, P.5    Aguilar-Bryan, L.6
  • 6
    • 0036460571 scopus 로고    scopus 로고
    • First-phase insulin response in young healthy children at genetic and immunological risk for Type I diabetes
    • PMID: 12488953
    • Keskinen P, Korhonen S, Kupila A, Veijola R, Erkkilä S, Savolainen H, et al. First-phase insulin response in young healthy children at genetic and immunological risk for Type I diabetes. Diabetologia. 2002; 45:1639-1648. PMID: 12488953 doi: 10.1007/s00125-002-0981-8
    • (2002) Diabetologia , vol.45 , pp. 1639-1648
    • Keskinen, P.1    Korhonen, S.2    Kupila, A.3    Veijola, R.4    Erkkilä, S.5    Savolainen, H.6
  • 7
    • 0019429846 scopus 로고
    • Cell populations in the endocrine pancreas of human neonates and infants
    • PMID: 6116638
    • Rahier J, Wallon J, Henquin JC. Cell populations in the endocrine pancreas of human neonates and infants. Diabetologia. 1981; 20:540-546. PMID: 6116638
    • (1981) Diabetologia , vol.20 , pp. 540-546
    • Rahier, J.1    Wallon, J.2    Henquin, J.C.3
  • 8
    • 0019448221 scopus 로고
    • Quantitation of the B and A cell fractions in human pancreas from early fetal life to puberty
    • PMID: 7021125
    • Wirdnam PK, Milner RD. Quantitation of the B and A cell fractions in human pancreas from early fetal life to puberty. Early Hum Dev. 1981; 5:299-309. PMID: 7021125
    • (1981) Early Hum Dev , vol.5 , pp. 299-309
    • Wirdnam, P.K.1    Milner, R.D.2
  • 9
    • 0020655416 scopus 로고
    • A quantitative immunofluorescent study of the endocrine cell populations in the developing human pancreas
    • PMID: 6131849
    • Stefan Y, Grasso S, Perrelet A, Orci L. A quantitative immunofluorescent study of the endocrine cell populations in the developing human pancreas. Diabetes. 1983; 32:293-301. PMID: 6131849
    • (1983) Diabetes , vol.32 , pp. 293-301
    • Stefan, Y.1    Grasso, S.2    Perrelet, A.3    Orci, L.4
  • 10
    • 44749088201 scopus 로고    scopus 로고
    • β-cell replication is the primary mechanism subserving the postnatal expansion of β-cell mass in humans
    • PMID: 18334605
    • Meier JJ, Butler AE, Saisho Y, Monchamp T, Galasso R, Bhushan A, et al. β-cell replication is the primary mechanism subserving the postnatal expansion of β-cell mass in humans. Diabetes. 2008; 57:1584-1594. PMID: 18334605 doi: 10.2337/db07-1369
    • (2008) Diabetes , vol.57 , pp. 1584-1594
    • Meier, J.J.1    Butler, A.E.2    Saisho, Y.3    Monchamp, T.4    Galasso, R.5    Bhushan, A.6
  • 11
    • 84866153904 scopus 로고    scopus 로고
    • Formation of a human β-cell population within pancreatic islets is set early in life
    • PMID: 22745242
    • Gregg BE, Moore PC, Demozay D, Hall BA, Li M, Husain A, et al. Formation of a human β-cell population within pancreatic islets is set early in life. J Clin Endocrinol Metab. 2012; 97:3197-3206. PMID: 22745242 doi: 10.1210/jc.2012-1206
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. 3197-3206
    • Gregg, B.E.1    Moore, P.C.2    Demozay, D.3    Hall, B.A.4    Li, M.5    Husain, A.6
  • 12
    • 0027497908 scopus 로고
    • The role of pancreatic insulin secretion in neonatal glucoregulation. I. Healthy term and preterm infants
    • PMID: 8466262
    • Hawdon JM, Aynsley-Green A, Alberti KG, Ward Platt MP. The role of pancreatic insulin secretion in neonatal glucoregulation. I. Healthy term and preterm infants. Arch Dis Child. 1993; 68:274-279. PMID: 8466262
    • (1993) Arch Dis Child , vol.68 , pp. 274-279
    • Hawdon, J.M.1    Aynsley-Green, A.2    Alberti, K.G.3    Ward Platt, M.P.4
  • 13
    • 84907953430 scopus 로고    scopus 로고
    • Neonatal and infant beta cell hormone concentrations in relation to type 1 diabetes risk
    • PMID: 24552441
    • Stumpp C, Beyerlein A, Ziegler AG, Bonifacio E. Neonatal and infant beta cell hormone concentrations in relation to type 1 diabetes risk. Pediatr Diabetes. 2014; 15:528-533. PMID: 24552441 doi: 10.1111/ pedi.12122
    • (2014) Pediatr Diabetes , vol.15 , pp. 528-533
    • Stumpp, C.1    Beyerlein, A.2    Ziegler, A.G.3    Bonifacio, E.4
  • 14
    • 0015180716 scopus 로고
    • The serum insulin and growth hormone response to arginine and to arginine with glucose in the premature infant
    • PMID: 5135634
    • Reitano G, Grasso S, Distefano G, Messina A. The serum insulin and growth hormone response to arginine and to arginine with glucose in the premature infant. J Clin Endocrinol Metab. 1971; 33:924-928. PMID: 5135634 doi: 10.1210/jcem-33-6-924
    • (1971) J Clin Endocrinol Metab , vol.33 , pp. 924-928
    • Reitano, G.1    Grasso, S.2    Distefano, G.3    Messina, A.4
  • 15
    • 0015618607 scopus 로고
    • Insulin secretion in the premature infant: Response to glucose and amino acids
    • PMID: 4700048
    • Grasso S, Messina A, Distefano G, Vigo R, Reitano G. Insulin secretion in the premature infant: Response to glucose and amino acids. Diabetes. 1973; 22:349-353. PMID: 4700048
    • (1973) Diabetes , vol.22 , pp. 349-353
    • Grasso, S.1    Messina, A.2    Distefano, G.3    Vigo, R.4    Reitano, G.5
  • 16
    • 0016381849 scopus 로고
    • Glucose metabolism and insulin secretion in the newborn infant. Comparisons between the responses observed the first and seventh day of life to intravenous and oral glucose tolerance tests
    • PMID: 4816889
    • Falorni A, Fracassini F, Massi-Benedetti F, Maffei S. Glucose metabolism and insulin secretion in the newborn infant. Comparisons between the responses observed the first and seventh day of life to intravenous and oral glucose tolerance tests. Diabetes. 1974; 23:172-178. PMID: 4816889
    • (1974) Diabetes , vol.23 , pp. 172-178
    • Falorni, A.1    Fracassini, F.2    Massi-Benedetti, F.3    Maffei, S.4
  • 17
    • 28444482424 scopus 로고    scopus 로고
    • Longitudinal changes in insulin sensitivity and secretion from birth to age three years in small- and appropriate-for-gestational-age children
    • PMID: 16283238
    • Mericq V, Ong KK, Bazaes R, Peña V, Avila A, Salazar T, et al. Longitudinal changes in insulin sensitivity and secretion from birth to age three years in small- and appropriate-for-gestational-age children. Diabetologia. 2005; 48:2609-2614. PMID: 16283238 doi: 10.1007/s00125-005-0036-z
    • (2005) Diabetologia , vol.48 , pp. 2609-2614
    • Mericq, V.1    Ong, K.K.2    Bazaes, R.3    Peña, V.4    Avila, A.5    Salazar, T.6
  • 18
    • 0025742834 scopus 로고
    • Relationship between firstphase insulin secretion and age, HLA, islet cell antibody status, and development of type I diabetes in 220 juvenile first-degree relatives of diabetic patients
    • PMID: 1954807
    • Robert JJ, Deschamps I, Chevenne D, Roger M, Mogenet A, Boitard C. Relationship between firstphase insulin secretion and age, HLA, islet cell antibody status, and development of type I diabetes in 220 juvenile first-degree relatives of diabetic patients. Diabetes Care. 1991; 14:718-723. PMID: 1954807
    • (1991) Diabetes Care , vol.14 , pp. 718-723
    • Robert, J.J.1    Deschamps, I.2    Chevenne, D.3    Roger, M.4    Mogenet, A.5    Boitard, C.6
  • 19
    • 0027197931 scopus 로고
    • Decreased insulin response to glucose in islet cell antibody-negative siblings of type 1 diabetic children
    • PMID: 8326015
    • Carel JC, Boitard C, Bougnères PF. Decreased insulin response to glucose in islet cell antibody-negative siblings of type 1 diabetic children. J Clin Invest. 1993; 92:509-513. PMID: 8326015 doi: 10.1172/ JCI116595
    • (1993) J Clin Invest , vol.92 , pp. 509-513
    • Carel, J.C.1    Boitard, C.2    Bougnères, P.F.3
  • 20
    • 0024364978 scopus 로고
    • Increased insulin secretion in puberty: A compensatory response to reductions in insulin sensitivity
    • PMID: 2524556
    • Caprio S, Plewe G, Diamond MP, Simonson DC, Boulware SD, Sherwin RS, et al. Increased insulin secretion in puberty: a compensatory response to reductions in insulin sensitivity. J Pediatr. 1989; 114:963-967. PMID: 2524556
    • (1989) J Pediatr , vol.114 , pp. 963-967
    • Caprio, S.1    Plewe, G.2    Diamond, M.P.3    Simonson, D.C.4    Boulware, S.D.5    Sherwin, R.S.6
  • 21
    • 0035131854 scopus 로고    scopus 로고
    • First-phase insulin release during the intravenous glucose tolerance test as a risk factor for type 1 diabetes
    • PMID: 11174623
    • Chase HP, Cuthbertson DD, Dolan LM, Kaufman F, Krischer JP, Schatz DA, et al. First-phase insulin release during the intravenous glucose tolerance test as a risk factor for type 1 diabetes. J Pediatr. 2001; 138:244-249. PMID: 11174623 doi: 10.1067/mpd.2001.111274
    • (2001) J Pediatr , vol.138 , pp. 244-249
    • Chase, H.P.1    Cuthbertson, D.D.2    Dolan, L.M.3    Kaufman, F.4    Krischer, J.P.5    Schatz, D.A.6
  • 22
    • 0031158813 scopus 로고    scopus 로고
    • Insulin secretion and sensitivity in black versus white prepubertal healthy children
    • PMID: 9177407
    • Arslanian S, Suprasongsin C, Janosky JE. Insulin secretion and sensitivity in black versus white prepubertal healthy children. J Clin Endocrinol Metab. 1997; 82:1923-1927. PMID: 9177407 doi: 10.1210/ jcem.82.6.4002
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 1923-1927
    • Arslanian, S.1    Suprasongsin, C.2    Janosky, J.E.3
  • 23
    • 0015306021 scopus 로고
    • Insulin release from human foetal pancreas in response to glucose, leucine and arginine
    • PMID: 4553012
    • Milner RD, Ashworth MA, Barson AJ. Insulin release from human foetal pancreas in response to glucose, leucine and arginine. J Endocrinol. 1972; 52:497-505. PMID: 4553012
    • (1972) J Endocrinol , vol.52 , pp. 497-505
    • Milner, R.D.1    Ashworth, M.A.2    Barson, A.J.3
  • 25
    • 0019795710 scopus 로고
    • Secretion and biosynthesis of (pro)insulin by pancreatic islets isolated from fetuses of normal and diabetic women
    • PMID: 7018946
    • Jahr H, Reiher H, Ziegler M, Schmidt S, Hahn HJ. Secretion and biosynthesis of (pro)insulin by pancreatic islets isolated from fetuses of normal and diabetic women. Diabetes Metab. 1981; 7:71-75. PMID: 7018946
    • (1981) Diabetes Metab , vol.7 , pp. 71-75
    • Jahr, H.1    Reiher, H.2    Ziegler, M.3    Schmidt, S.4    Hahn, H.J.5
  • 27
    • 0028829481 scopus 로고
    • Constitution of a biphasic insulin response to glucose in human fetal pancreatic β-cells with glucagon-like peptide 1
    • PMID: 8530635
    • Otonkoski T, Hayek A. Constitution of a biphasic insulin response to glucose in human fetal pancreatic β-cells with glucagon-like peptide 1. J Clin Endocrinol Metab. 1995; 80:3779-3783. PMID: 8530635 doi: 10.1210/jcem.80.12.8530635
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 3779-3783
    • Otonkoski, T.1    Hayek, A.2
  • 28
    • 0031024786 scopus 로고    scopus 로고
    • Expression of glucokinase in glucose-unresponsive human fetal pancreatic islet-like cell clusters
    • PMID: 9062511
    • Tu J, Tuch BE. Expression of glucokinase in glucose-unresponsive human fetal pancreatic islet-like cell clusters. J Clin Endocrinol Metab. 1997; 82:943-948. PMID: 9062511 doi: 10.1210/jcem.82.3. 3837
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 943-948
    • Tu, J.1    Tuch, B.E.2
  • 29
    • 0023872502 scopus 로고
    • Maturation of insulin response to glucose during human fetal and neonatal development: Studies with perifusion of pancreatic islet-like cell clusters
    • PMID: 3286329
    • Otonkoski T, Andersson S, Knip M, Simell O. Maturation of insulin response to glucose during human fetal and neonatal development: Studies with perifusion of pancreatic islet-like cell clusters. Diabetes. 1988; 37:286-291. PMID: 3286329
    • (1988) Diabetes , vol.37 , pp. 286-291
    • Otonkoski, T.1    Andersson, S.2    Knip, M.3    Simell, O.4
  • 30
    • 33745781867 scopus 로고    scopus 로고
    • Suitability of human juvenile pancreatic islets for clinical use
    • PMID: 16783471
    • Balamurugan AN, Chang Y, Bertera S, Sands A, Shankar V, Trucco M, et al. Suitability of human juvenile pancreatic islets for clinical use. Diabetologia. 2006; 49:1845-1854. PMID: 16783471 doi: 10. 1007/s00125-006-0318-0
    • (2006) Diabetologia , vol.49 , pp. 1845-1854
    • Balamurugan, A.N.1    Chang, Y.2    Bertera, S.3    Sands, A.4    Shankar, V.5    Trucco, M.6
  • 31
    • 80053411257 scopus 로고    scopus 로고
    • Vitro insulin secretion by pancreatic tissue from infants with diazoxide-resistant congenital hyperinsulinism deviates from model predictions
    • PMID: 21968111
    • Henquin JC, Nenquin M, Sempoux C, Guiot Y, Bellanné-Chantelot C, Otonkoski T, et al. In vitro insulin secretion by pancreatic tissue from infants with diazoxide-resistant congenital hyperinsulinism deviates from model predictions. J Clin Invest. 2011; 121:3932-3942. PMID: 21968111 doi: 10.1172/ JCI58400
    • (2011) J Clin Invest , vol.121 , pp. 3932-3942
    • Henquin, J.C.1    Nenquin, M.2    Sempoux, C.3    Guiot, Y.4    Bellanné-Chantelot, C.5    Otonkoski, T.6
  • 32
    • 84875853629 scopus 로고    scopus 로고
    • Functional plasticity of the human infant β-cell exocytotic phenotype
    • PMID: 23449893
    • Manning Fox JE, Seeberger K, Dai XQ, Lyon J, Spigelman AF, Kolic J, et al. Functional plasticity of the human infant β-cell exocytotic phenotype. Endocrinology. 2013; 154:1392-1399. PMID: 23449893 doi: 10.1210/en.2012-1934
    • (2013) Endocrinology , vol.154 , pp. 1392-1399
    • Manning Fox, J.E.1    Seeberger, K.2    Dai, X.Q.3    Lyon, J.4    Spigelman, A.F.5    Kolic, J.6
  • 33
    • 33845541249 scopus 로고    scopus 로고
    • Nutrient control of insulin secretion in isolated normal human islets
    • PMID: 17130494
    • Henquin JC, Dufrane D, Nenquin M. Nutrient control of insulin secretion in isolated normal human islets. Diabetes. 2006; 55:3470-3477. PMID: 17130494 doi: 10.2337/db06-0868
    • (2006) Diabetes , vol.55 , pp. 3470-3477
    • Henquin, J.C.1    Dufrane, D.2    Nenquin, M.3
  • 34
    • 84943329412 scopus 로고    scopus 로고
    • Dynamics of glucose-induced insulin secretion in normal human islets
    • PMID: 26264556
    • Henquin JC, Dufrane D, Kerr-Conte J, Nenquin M. Dynamics of glucose-induced insulin secretion in normal human islets. Am J Physiol Endocrinol Metab. 2015; 309:E640-E650. PMID: 26264556 doi: 10.1152/ajpendo.00251.2015
    • (2015) Am J Physiol Endocrinol Metab , vol.309 , pp. E640-E650
    • Henquin, J.C.1    Dufrane, D.2    Kerr-Conte, J.3    Nenquin, M.4
  • 35
    • 0029833117 scopus 로고    scopus 로고
    • Stable and diffusible pools of nucleotides in pancreatic islet cells
    • PMID: 8895332
    • Detimary P, Jonas JC, Henquin JC. Stable and diffusible pools of nucleotides in pancreatic islet cells. Endocrinology. 1996; 137:4671-4676. PMID: 8895332 doi: 10.1210/endo.137.11.8895332
    • (1996) Endocrinology , vol.137 , pp. 4671-4676
    • Detimary, P.1    Jonas, J.C.2    Henquin, J.C.3
  • 36
    • 33645074184 scopus 로고    scopus 로고
    • Dual mechanism of the potentiation by glucose of insulin secretion induced by arginine and tolbutamide in mouse islets
    • PMID: 16249257
    • Ishiyama N, Ravier MA, Henquin JC. Dual mechanism of the potentiation by glucose of insulin secretion induced by arginine and tolbutamide in mouse islets. Am J Physiol Endocrinol Metab. 2006; 290: E540-E549. PMID: 16249257 doi: 10.1152/ajpendo.00032.2005
    • (2006) Am J Physiol Endocrinol Metab , vol.290 , pp. E540-E549
    • Ishiyama, N.1    Ravier, M.A.2    Henquin, J.C.3
  • 37
    • 0033324984 scopus 로고    scopus 로고
    • +channels in β-cells
    • PMID: 10218978
    • Sato Y, Anello M, Henquin JC. Glucose regulation of insulin secretion independent of the opening or closure of adenosine triphosphate-sensitive K+ channels in β-cells. Endocrinology. 1999; 140:2252-2257. PMID: 10218978 doi: 10.1210/endo.140.5.6729
    • (1999) Endocrinology , vol.140 , pp. 2252-2257
    • Sato, Y.1    Anello, M.2    Henquin, J.C.3
  • 38
    • 0031966603 scopus 로고    scopus 로고
    • Pancreatic β-cell proliferation in persistent hyperinsulinemic hypoglycemia of infancy: An immunohistochemical study of 18 cases
    • PMID: 9619597
    • Sempoux C, Guiot Y, Dubois D, Nollevaux MC, Saudubray JM, Nihoul-Fekete C, et al. Pancreatic β-cell proliferation in persistent hyperinsulinemic hypoglycemia of infancy: an immunohistochemical study of 18 cases. Mod Pathol. 1998; 11:444-449. PMID: 9619597
    • (1998) Mod Pathol , vol.11 , pp. 444-449
    • Sempoux, C.1    Guiot, Y.2    Dubois, D.3    Nollevaux, M.C.4    Saudubray, J.M.5    Nihoul-Fekete, C.6
  • 39
    • 0033853921 scopus 로고    scopus 로고
    • β-cell proliferation and apoptosis in the developing normal human pancreas and in hyperinsulinism of infancy
    • PMID: 10923633
    • Kassem SA, Ariel I, Thornton PS, Scheimberg I, Glaser B. β-cell proliferation and apoptosis in the developing normal human pancreas and in hyperinsulinism of infancy. Diabetes. 2000; 49:1325-1333. PMID: 10923633
    • (2000) Diabetes , vol.49 , pp. 1325-1333
    • Kassem, S.A.1    Ariel, I.2    Thornton, P.S.3    Scheimberg, I.4    Glaser, B.5
  • 40
    • 0020013186 scopus 로고
    • The endocrine pancreas of the neonate and infant
    • PMID: 6289239
    • Jaffe R, Hashida Y, Yunis EJ. The endocrine pancreas of the neonate and infant. Perspect Pediatr Pathol. 1982; 7:137-165. PMID: 6289239
    • (1982) Perspect Pediatr Pathol , vol.7 , pp. 137-165
    • Jaffe, R.1    Hashida, Y.2    Yunis, E.J.3
  • 41
    • 0347306075 scopus 로고    scopus 로고
    • Intraislet somatostatin inhibits insulin (via a subtype-2 somatostatin receptor) but not islet amyloid polypeptide secretion in the isolated perfused human pancreas
    • PMID: 9834355
    • Atiya AW, Moldovan S, Adrian TE, Coy D, Walsh J, Brunicardi FC. Intraislet somatostatin inhibits insulin (via a subtype-2 somatostatin receptor) but not islet amyloid polypeptide secretion in the isolated perfused human pancreas. J Gastrointest Surg. 1997; 1:251-256. PMID: 9834355
    • (1997) J Gastrointest Surg , vol.1 , pp. 251-256
    • Atiya, A.W.1    Moldovan, S.2    Adrian, T.E.3    Coy, D.4    Walsh, J.5    Brunicardi, F.C.6
  • 42
    • 63249127193 scopus 로고    scopus 로고
    • Somatostatin secreted by islet delta-cells fulfills multiple roles as a paracrine regulator of islet function
    • PMID: 18984743
    • Hauge-Evans AC, King AJ, Carmignac D, Richardson CC, Robinson IC, Low MJ, et al. Somatostatin secreted by islet delta-cells fulfills multiple roles as a paracrine regulator of islet function. Diabetes. 2009; 58:403-411. PMID: 18984743 doi: 10.2337/db08-0792
    • (2009) Diabetes , vol.58 , pp. 403-411
    • Hauge-Evans, A.C.1    King, A.J.2    Carmignac, D.3    Richardson, C.C.4    Robinson, I.C.5    Low, M.J.6
  • 43
    • 34147107031 scopus 로고    scopus 로고
    • + ATP channels in human pancreatic beta cells early in development
    • PMID: 17380317
    • Richardson CC, Hussain K, Jones PM, Persaud SJ, Löbner K, Boehm A, et al. Low levels of glucose transporters and K+ ATP channels in human pancreatic beta cells early in development. Diabetologia. 2007; 50:1000-1005. PMID: 17380317 doi: 10.1007/s00125-007-0644-x
    • (2007) Diabetologia , vol.50 , pp. 1000-1005
    • Richardson, C.C.1    Hussain, K.2    Jones, P.M.3    Persaud, S.J.4    Löbner, K.5    Boehm, A.6
  • 44
    • 84876522789 scopus 로고    scopus 로고
    • Congenital hyperinsulinism caused by hexokinase I expression or glucokinase-activating mutation in a subset of β-cells
    • PMID: 23274908
    • Henquin JC, Sempoux C, Marchandise J, Godecharles S, Guiot Y, Nenquin M, et al. Congenital hyperinsulinism caused by hexokinase I expression or glucokinase-activating mutation in a subset of β-cells. Diabetes. 2013; 62:1689-1696. PMID: 23274908 doi: 10.2337/db12-1414
    • (2013) Diabetes , vol.62 , pp. 1689-1696
    • Henquin, J.C.1    Sempoux, C.2    Marchandise, J.3    Godecharles, S.4    Guiot, Y.5    Nenquin, M.6
  • 45
    • 84924314941 scopus 로고    scopus 로고
    • Weaning triggers a maturation step of pancreatic β cells
    • PMID: 25662175
    • Stolovich-Rain M, Enk J, Vikesa J, Nielsen FC, Saada A, Glaser B, et al. Weaning triggers a maturation step of pancreatic β cells. Dev Cell. 2015; 32:535-545. PMID: 25662175 doi: 10.1016/j.devcel.2015. 01.002
    • (2015) Dev Cell , vol.32 , pp. 535-545
    • Stolovich-Rain, M.1    Enk, J.2    Vikesa, J.3    Nielsen, F.C.4    Saada, A.5    Glaser, B.6
  • 46
    • 84936797255 scopus 로고    scopus 로고
    • DNA methylation directs functional maturation of pancreatic β cells
    • PMID: 26098213
    • Dhawan S, Tschen SI, Zeng C, Guo T, Hebrok M, Matveyenko A, et al. DNA methylation directs functional maturation of pancreatic β cells. J Clin Invest. 2015; 125:2851-2860. PMID: 26098213 doi: 10. 1172/JCI79956
    • (2015) J Clin Invest , vol.125 , pp. 2851-2860
    • Dhawan, S.1    Tschen, S.I.2    Zeng, C.3    Guo, T.4    Hebrok, M.5    Matveyenko, A.6
  • 47
    • 84940831580 scopus 로고    scopus 로고
    • Postnatal β-cell maturation is associated with islet-specific microRNA changes induced by nutrient shifts at weaning
    • PMID: 26330140
    • Jacovetti C, Matkovich SJ, Rodriguez-Trejo A, Guay C, Regazzi R. Postnatal β-cell maturation is associated with islet-specific microRNA changes induced by nutrient shifts at weaning. Nat Commun. 2015; 6:8084. PMID: 26330140 doi: 10.1038/ncomms9084
    • (2015) Nat Commun , vol.6 , pp. 8084
    • Jacovetti, C.1    Matkovich, S.J.2    Rodriguez-Trejo, A.3    Guay, C.4    Regazzi, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.