-
1
-
-
84866364390
-
The anatomical and cellular basis of immune surveillance in the central nervous system
-
Ransohoff RM, Engelhardt B. The anatomical and cellular basis of immune surveillance in the central nervous system. Nat Rev Immunol (2012) 12:623-35. doi: 10.1038/nri3265
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 623-635
-
-
Ransohoff, R.M.1
Engelhardt, B.2
-
2
-
-
84983048399
-
Multifaceted interactions between adaptive immunity and the central nervous system
-
Kipnis J. Multifaceted interactions between adaptive immunity and the central nervous system. Science (2016) 353:766-71. doi:10.1126/science.aag2638
-
(2016)
Science
, vol.353
, pp. 766-771
-
-
Kipnis, J.1
-
3
-
-
84995487522
-
Lymphatics in neurological disorders: a neuro-lympho-vascular component of multiple sclerosis and Alzheimer's disease
-
Louveau A, Da Mesquita S, Kipnis J. Lymphatics in neurological disorders: a neuro-lympho-vascular component of multiple sclerosis and Alzheimer's disease? Neuron (2016) 91:957-73. doi:10.1016/j.neuron.2016.08.027
-
(2016)
Neuron
, vol.91
, pp. 957-973
-
-
Louveau, A.1
Da Mesquita, S.2
Kipnis, J.3
-
4
-
-
77950858637
-
Microglia in neurodegenerative disease
-
Perry VH, Nicoll JA, Holmes C. Microglia in neurodegenerative disease. Nat Rev Neurol (2010) 6:193-201. doi:10.1038/nrneurol.2010.17
-
(2010)
Nat Rev Neurol
, vol.6
, pp. 193-201
-
-
Perry, V.H.1
Nicoll, J.A.2
Holmes, C.3
-
5
-
-
84911092143
-
Macrophage heterogeneity in tissues: phenotypic diversity and functions
-
Gordon S, Pluddemann A, Martinez Estrada F. Macrophage heterogeneity in tissues: phenotypic diversity and functions. Immunol Rev (2014) 262:36-55. doi:10.1111/imr.12223
-
(2014)
Immunol Rev
, vol.262
, pp. 36-55
-
-
Gordon, S.1
Pluddemann, A.2
Martinez Estrada, F.3
-
6
-
-
84921637630
-
Ontogeny and functions of central nervous system macrophages
-
Katsumoto A, Lu H, Miranda AS, Ransohoff RM. Ontogeny and functions of central nervous system macrophages. J Immunol (2014) 193:2615-21. doi:10.4049/jimmunol.1400716
-
(2014)
J Immunol
, vol.193
, pp. 2615-2621
-
-
Katsumoto, A.1
Lu, H.2
Miranda, A.S.3
Ransohoff, R.M.4
-
7
-
-
84899418705
-
Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease
-
Prinz M, Priller J. Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease. Nat Rev Neurosci (2014) 15:300-12. doi:10.1038/nrn3722
-
(2014)
Nat Rev Neurosci
, vol.15
, pp. 300-312
-
-
Prinz, M.1
Priller, J.2
-
8
-
-
78149360132
-
Fate mapping analysis reveals that adult microglia derive from primitive macrophages
-
Ginhoux F, Greter M, Leboeuf M, Nandi S, See P, Gokhan S, et al. Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science (2010) 330:841-5. doi:10.1126/science.1194637
-
(2010)
Science
, vol.330
, pp. 841-845
-
-
Ginhoux, F.1
Greter, M.2
Leboeuf, M.3
Nandi, S.4
See, P.5
Gokhan, S.6
-
9
-
-
36448994709
-
Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
-
Ajami B, Bennett JL, Krieger C, Tetzlaff W, Rossi FM. Local self-renewal can sustain CNS microglia maintenance and function throughout adult life. Nat Neurosci (2007) 10:1538-43. doi:10.1038/nn2014
-
(2007)
Nat Neurosci
, vol.10
, pp. 1538-1543
-
-
Ajami, B.1
Bennett, J.L.2
Krieger, C.3
Tetzlaff, W.4
Rossi, F.M.5
-
10
-
-
84875892857
-
Microglia emerge from erythromyeloid precursors via Pu.1-and Irf8-dependent pathways
-
Kierdorf K, Erny D, Goldmann T, Sander V, Schulz C, Perdiguero EG, et al. Microglia emerge from erythromyeloid precursors via Pu.1-and Irf8-dependent pathways. Nat Neurosci (2013) 16:273-80. doi:10.1038/nn.3318
-
(2013)
Nat Neurosci
, vol.16
, pp. 273-280
-
-
Kierdorf, K.1
Erny, D.2
Goldmann, T.3
Sander, V.4
Schulz, C.5
Perdiguero, E.G.6
-
11
-
-
84867740805
-
Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
-
Gautier EL, Shay T, Miller J, Greter M, Jakubzick C, Ivanov S, et al. Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages. Nat Immunol (2012) 13:1118-28. doi:10.1038/ni.2419
-
(2012)
Nat Immunol
, vol.13
, pp. 1118-1128
-
-
Gautier, E.L.1
Shay, T.2
Miller, J.3
Greter, M.4
Jakubzick, C.5
Ivanov, S.6
-
12
-
-
84880802569
-
A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model
-
Chiu IM, Morimoto ET, Goodarzi H, Liao JT, O'Keeffe S, Phatnani HP, et al. A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model. Cell Rep (2013) 4:385-401. doi:10.1016/j.celrep.2013.06.018
-
(2013)
Cell Rep
, vol.4
, pp. 385-401
-
-
Chiu, I.M.1
Morimoto, E.T.2
Goodarzi, H.3
Liao, J.T.4
O'Keeffe, S.5
Phatnani, H.P.6
-
13
-
-
84893202052
-
Integrated expression profiles of mRNA and miRNA in polarized primary murine microglia
-
Freilich RW, Woodbury ME, Ikezu T. Integrated expression profiles of mRNA and miRNA in polarized primary murine microglia. PLoS One (2013) 8:e79416. doi:10.1371/journal.pone.0079416
-
(2013)
PLoS One
, vol.8
-
-
Freilich, R.W.1
Woodbury, M.E.2
Ikezu, T.3
-
14
-
-
84888324248
-
The microglial sensome revealed by direct RNA sequencing
-
Hickman SE, Kingery ND, Ohsumi TK, Borowsky ML, Wang LC, Means TK, et al. The microglial sensome revealed by direct RNA sequencing. Nat Neurosci (2013) 16:1896-905. doi:10.1038/nn.3554
-
(2013)
Nat Neurosci
, vol.16
, pp. 1896-1905
-
-
Hickman, S.E.1
Kingery, N.D.2
Ohsumi, T.K.3
Borowsky, M.L.4
Wang, L.C.5
Means, T.K.6
-
15
-
-
84893745524
-
Identification of a unique TGF-beta-dependent molecular and functional signature in microglia
-
Butovsky O, Jedrychowski MP, Moore CS, Cialic R, Lanser AJ, Gabriely G, et al. Identification of a unique TGF-beta-dependent molecular and functional signature in microglia. Nat Neurosci (2014) 17:131-43. doi:10.1038/nn.3599
-
(2014)
Nat Neurosci
, vol.17
, pp. 131-143
-
-
Butovsky, O.1
Jedrychowski, M.P.2
Moore, C.S.3
Cialic, R.4
Lanser, A.J.5
Gabriely, G.6
-
16
-
-
84920724792
-
Environment drives selection and function of enhancers controlling tissue-specific macrophage identities
-
Gosselin D, Link VM, Romanoski CE, Fonseca GJ, Eichenfield DZ, Spann NJ, et al. Environment drives selection and function of enhancers controlling tissue-specific macrophage identities. Cell (2014) 159:1327-40. doi:10.1016/j.cell.2014.11.023
-
(2014)
Cell
, vol.159
, pp. 1327-1340
-
-
Gosselin, D.1
Link, V.M.2
Romanoski, C.E.3
Fonseca, G.J.4
Eichenfield, D.Z.5
Spann, N.J.6
-
17
-
-
84920724791
-
Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment
-
Lavin Y, Winter D, Blecher-Gonen R, David E, Keren-Shaul H, Merad M, et al. Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment. Cell (2014) 159:1312-26. doi:10.1016/j.cell.2014.11.018
-
(2014)
Cell
, vol.159
, pp. 1312-1326
-
-
Lavin, Y.1
Winter, D.2
Blecher-Gonen, R.3
David, E.4
Keren-Shaul, H.5
Merad, M.6
-
18
-
-
84885173894
-
Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice
-
Orre M, Kamphuis W, Osborn LM, Melief J, Kooijman L, Huitinga I, et al. Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice. Neurobiol Aging (2014) 35:1-14. doi:10.1016/j.neurobiolaging.2013.07.008
-
(2014)
Neurobiol Aging
, vol.35
, pp. 1-14
-
-
Orre, M.1
Kamphuis, W.2
Osborn, L.M.3
Melief, J.4
Kooijman, L.5
Huitinga, I.6
-
19
-
-
84906901689
-
An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex
-
Zhang Y, Chen K, Sloan SA, Bennett ML, Scholze AR, O'Keeffe S, et al. An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex. J Neurosci (2014) 34:11929-47. doi:10.1523/JNEUROSCI.1860-14.2014
-
(2014)
J Neurosci
, vol.34
, pp. 11929-11947
-
-
Zhang, Y.1
Chen, K.2
Sloan, S.A.3
Bennett, M.L.4
Scholze, A.R.5
O'Keeffe, S.6
-
20
-
-
84962250196
-
New tools for studying microglia in the mouse and human CNS
-
Bennett ML, Bennett FC, Liddelow SA, Ajami B, Zamanian JL, Fernhoff NB, et al. New tools for studying microglia in the mouse and human CNS. Proc Natl Acad Sci U S A (2016) 113:E1738-46. doi:10.1073/pnas.1525528113
-
(2016)
Proc Natl Acad Sci U S A
, vol.113
, pp. E1738-E1746
-
-
Bennett, M.L.1
Bennett, F.C.2
Liddelow, S.A.3
Ajami, B.4
Zamanian, J.L.5
Fernhoff, N.B.6
-
21
-
-
0025220976
-
Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain
-
Lawson LJ, Perry VH, Dri P, Gordon S. Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain. Neuroscience (1990) 39:151-70. doi:10.1016/0306-4522(90)90229-W
-
(1990)
Neuroscience
, vol.39
, pp. 151-170
-
-
Lawson, L.J.1
Perry, V.H.2
Dri, P.3
Gordon, S.4
-
22
-
-
65249157852
-
Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals
-
Wake H, Moorhouse AJ, Jinno S, Kohsaka S, Nabekura J. Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals. J Neurosci (2009) 29:3974-80. doi:10.1523/JNEUROSCI.4363-08.2009
-
(2009)
J Neurosci
, vol.29
, pp. 3974-3980
-
-
Wake, H.1
Moorhouse, A.J.2
Jinno, S.3
Kohsaka, S.4
Nabekura, J.5
-
23
-
-
77957328867
-
Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis
-
Sierra A, Encinas JM, Deudero JJ, Chancey JH, Enikolopov G, Overstreet-Wadiche LS, et al. Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis. Cell Stem Cell (2010) 7:483-95. doi:10.1016/j.stem.2010.08.014
-
(2010)
Cell Stem Cell
, vol.7
, pp. 483-495
-
-
Sierra, A.1
Encinas, J.M.2
Deudero, J.J.3
Chancey, J.H.4
Enikolopov, G.5
Overstreet-Wadiche, L.S.6
-
24
-
-
78649976052
-
Microglial interactions with synapses are modulated by visual experience
-
Tremblay ME, Lowery RL, Majewska AK. Microglial interactions with synapses are modulated by visual experience. PLoS Biol (2010) 8:e1000527. doi:10.1371/journal.pbio.1000527
-
(2010)
PLoS Biol
, vol.8
-
-
Tremblay, M.E.1
Lowery, R.L.2
Majewska, A.K.3
-
25
-
-
80052633284
-
Synaptic pruning by microglia is necessary for normal brain development
-
Paolicelli RC, Bolasco G, Pagani F, Maggi L, Scianni M, Panzanelli P, et al. Synaptic pruning by microglia is necessary for normal brain development. Science (2011) 333:1456-8. doi:10.1126/science.1202529
-
(2011)
Science
, vol.333
, pp. 1456-1458
-
-
Paolicelli, R.C.1
Bolasco, G.2
Pagani, F.3
Maggi, L.4
Scianni, M.5
Panzanelli, P.6
-
26
-
-
84861427387
-
Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner
-
Schafer DP, Lehrman EK, Kautzman AG, Koyama R, Mardinly AR, Yamasaki R, et al. Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner. Neuron (2012) 74:691-705. doi:10.1016/j.neuron.2012.03.026
-
(2012)
Neuron
, vol.74
, pp. 691-705
-
-
Schafer, D.P.1
Lehrman, E.K.2
Kautzman, A.G.3
Koyama, R.4
Mardinly, A.R.5
Yamasaki, R.6
-
27
-
-
84923238571
-
Microglia: multitasking specialists of the brain
-
Casano AM, Peri F. Microglia: multitasking specialists of the brain. Dev Cell (2015) 32:469-77. doi:10.1016/j.devcel.2015.01.018
-
(2015)
Dev Cell
, vol.32
, pp. 469-477
-
-
Casano, A.M.1
Peri, F.2
-
29
-
-
85009165788
-
Coupled proliferation and apoptosis maintain the rapid turnover of microglia in the adult brain
-
Askew K, Li K, Olmos-Alonso A, Garcia-Moreno F, Liang Y, Richardson P, et al. Coupled proliferation and apoptosis maintain the rapid turnover of microglia in the adult brain. Cell Rep (2017) 18:391-405. doi:10.1016/j.celrep.2016.12.041
-
(2017)
Cell Rep
, vol.18
, pp. 391-405
-
-
Askew, K.1
Li, K.2
Olmos-Alonso, A.3
Garcia-Moreno, F.4
Liang, Y.5
Richardson, P.6
-
30
-
-
22244464662
-
ATP mediates rapid microglial response to local brain injury in vivo
-
Davalos D, Grutzendler J, Yang G, Kim JV, Zuo Y, Jung S, et al. ATP mediates rapid microglial response to local brain injury in vivo. Nat Neurosci (2005) 8:752-8. doi:10.1038/nn1472
-
(2005)
Nat Neurosci
, vol.8
, pp. 752-758
-
-
Davalos, D.1
Grutzendler, J.2
Yang, G.3
Kim, J.V.4
Zuo, Y.5
Jung, S.6
-
31
-
-
19744380563
-
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
-
Nimmerjahn A, Kirchhoff F, Helmchen F. Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science (2005) 308:1314-8. doi:10.1126/science.1110647
-
(2005)
Science
, vol.308
, pp. 1314-1318
-
-
Nimmerjahn, A.1
Kirchhoff, F.2
Helmchen, F.3
-
32
-
-
84898028606
-
What is microglia neurotoxicity (not)
-
Biber K, Owens T, Boddeke E. What is microglia neurotoxicity (not)? Glia (2014) 62:841-54. doi:10.1002/glia.22654
-
(2014)
Glia
, vol.62
, pp. 841-854
-
-
Biber, K.1
Owens, T.2
Boddeke, E.3
-
33
-
-
84922658111
-
Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1
-
Szulzewsky F, Pelz A, Feng X, Synowitz M, Markovic D, Langmann T, et al. Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1. PLoS One (2015) 10:e0116644. doi:10.1371/journal.pone.0116644
-
(2015)
PLoS One
, vol.10
-
-
Szulzewsky, F.1
Pelz, A.2
Feng, X.3
Synowitz, M.4
Markovic, D.5
Langmann, T.6
-
34
-
-
35548986304
-
Microglia: active sensor and versatile effector cells in the normal and pathologic brain
-
Hanisch UK, Kettenmann H. Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci (2007) 10:1387-94. doi:10.1038/nn1997
-
(2007)
Nat Neurosci
, vol.10
, pp. 1387-1394
-
-
Hanisch, U.K.1
Kettenmann, H.2
-
35
-
-
67650966680
-
Microglial physiology: unique stimuli, specialized responses
-
Ransohoff RM, Perry VH. Microglial physiology: unique stimuli, specialized responses. Annu Rev Immunol (2009) 27:119-45. doi:10.1146/annurev.immunol.021908.132528
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 119-145
-
-
Ransohoff, R.M.1
Perry, V.H.2
-
36
-
-
80053233055
-
Heterogeneity of CNS myeloid cells and their roles in neurodegeneration
-
Prinz M, Priller J, Sisodia SS, Ransohoff RM. Heterogeneity of CNS myeloid cells and their roles in neurodegeneration. Nat Neurosci (2011) 14:1227-35. doi:10.1038/nn.2923
-
(2011)
Nat Neurosci
, vol.14
, pp. 1227-1235
-
-
Prinz, M.1
Priller, J.2
Sisodia, S.S.3
Ransohoff, R.M.4
-
37
-
-
84872176512
-
Microglia: new roles for the synaptic stripper
-
Kettenmann H, Kirchhoff F, Verkhratsky A. Microglia: new roles for the synaptic stripper. Neuron (2013) 77:10-8. doi:10.1016/j.neuron.2012.12.023
-
(2013)
Neuron
, vol.77
, pp. 10-18
-
-
Kettenmann, H.1
Kirchhoff, F.2
Verkhratsky, A.3
-
38
-
-
84960153701
-
Characterization of inflammatory markers and transcriptome profiles of differentially activated embryonic stem cell-derived microglia
-
Beins E, Ulas T, Ternes S, Neumann H, Schultze JL, Zimmer A. Characterization of inflammatory markers and transcriptome profiles of differentially activated embryonic stem cell-derived microglia. Glia (2016) 64:1007-20. doi:10.1002/glia.22979
-
(2016)
Glia
, vol.64
, pp. 1007-1020
-
-
Beins, E.1
Ulas, T.2
Ternes, S.3
Neumann, H.4
Schultze, J.L.5
Zimmer, A.6
-
39
-
-
84979730436
-
A polarizing question: do M1 and M2 microglia exist
-
Ransohoff RM. A polarizing question: do M1 and M2 microglia exist? Nat Neurosci (2016) 19:987-91. doi:10.1038/nn.4338
-
(2016)
Nat Neurosci
, vol.19
, pp. 987-991
-
-
Ransohoff, R.M.1
-
40
-
-
0036937354
-
Mesoglia & microglia-a historical review of the concept of mononuclear phagocytes within the central nervous system
-
Rezaie P, Male D. Mesoglia & microglia-a historical review of the concept of mononuclear phagocytes within the central nervous system. J Hist Neurosci (2002) 11:325-74. doi:10.1076/jhin.11.4.325.8531
-
(2002)
J Hist Neurosci
, vol.11
, pp. 325-374
-
-
Rezaie, P.1
Male, D.2
-
43
-
-
84927753939
-
From the cajal alumni achucarro and rio-hortega to the rediscovery of never-resting microglia
-
Tremblay ME, Lecours C, Samson L, Sanchez-Zafra V, Sierra A. From the cajal alumni achucarro and rio-hortega to the rediscovery of never-resting microglia. Front Neuroanat (2015) 9:45. doi:10.3389/fnana.2015.00045
-
(2015)
Front Neuroanat
, vol.9
, pp. 45
-
-
Tremblay, M.E.1
Lecours, C.2
Samson, L.3
Sanchez-Zafra, V.4
Sierra, A.5
-
45
-
-
34548757158
-
A historical reflection of the contributions of Cajal and Golgi to the foundations of neuroscience
-
De Carlos JA, Borrell J. A historical reflection of the contributions of Cajal and Golgi to the foundations of neuroscience. Brain Res Rev (2007) 55:8-16. doi:10.1016/j.brainresrev.2007.03.010
-
(2007)
Brain Res Rev
, vol.55
, pp. 8-16
-
-
De Carlos, J.A.1
Borrell, J.2
-
47
-
-
0001619989
-
Contribucion al conocimiento de la neuroglia del cerebro humano
-
Cajal SR. Contribucion al conocimiento de la neuroglia del cerebro humano. Trab Lab Invest Biol (1913) 11:255-315.
-
(1913)
Trab Lab Invest Biol
, vol.11
, pp. 255-315
-
-
Cajal, S.R.1
-
48
-
-
85017144140
-
Santiago Ramón y Cajal-Nobel Lecture: The Structure and Connexions of Neurons
-
Cajal SR. Santiago Ramón y Cajal-Nobel Lecture: The Structure and Connexions of Neurons. Nobelprize.org. Nobel Media AB 2014 (1906). Available from: http://www.nobelprize.org/nobel_prizes/medicine/laureates/1906/cajal-lecture.html
-
(1906)
Nobelprize.org Nobel Media AB 2014
-
-
Cajal, S.R.1
-
49
-
-
85017168448
-
Camillo Golgi-Nobel Lecture: The Neuron Doctrine
-
Theory and Facts. Nobelprize.org. Nobel Media AB 2014
-
Golgi C. Camillo Golgi-Nobel Lecture: The Neuron Doctrine. Theory and Facts. Nobelprize.org. Nobel Media AB 2014 (1906). Available from: http://www.nobelprize.org/nobel_prizes/medicine/laureates/1906/golgi-lecture.html
-
(1906)
-
-
Golgi, C.1
-
50
-
-
84903007962
-
Nuevo método para el estudio de la neuroglía y del tejido conjuntivo
-
Achúcarro N. Nuevo método para el estudio de la neuroglía y del tejido conjuntivo. Bol Soc Esp Biol (1911) I:139-41.
-
(1911)
Bol Soc Esp Biol
, vol.1
, pp. 139-141
-
-
Achúcarro, N.1
-
51
-
-
0003136108
-
El tercer elemento de los centros nerviosos
-
RioHortega PD. El tercer elemento de los centros nerviosos. Bol Soc Esp Biol (1919) 9:69-120.
-
(1919)
Bol Soc Esp Biol
, vol.9
, pp. 69-120
-
-
RioHortega, P.D.1
-
52
-
-
84990834234
-
The "Big-Bang" for modern glial biology: translation and comments on Pio del Rio-Hortega 1919 series of papers on microglia
-
Sierra A, de Castro F, Del Rio-Hortega J, Rafael Iglesias-Rozas J, Garrosa M, Kettenmann H. The "Big-Bang" for modern glial biology: translation and comments on Pio del Rio-Hortega 1919 series of papers on microglia. Glia (2016) 64:1801-40. doi:10.1002/glia.23046
-
(2016)
Glia
, vol.64
, pp. 1801-1840
-
-
Sierra, A.1
de Castro, F.2
Del Rio-Hortega, J.3
Rafael Iglesias-Rozas, J.4
Garrosa, M.5
Kettenmann, H.6
-
53
-
-
0012453525
-
Cultivo "in vitro" de microglía
-
Costero I. Cultivo "in vitro" de microglía. Bol R Soc Esp Hist Nat (1930) 30:165-71.
-
(1930)
Bol R Soc Esp Hist Nat
, vol.30
, pp. 165-171
-
-
Costero, I.1
-
54
-
-
0014369295
-
Displacement of synaptic terminals from regenerating motoneurons by microglial cells
-
Blinzinger K, Kreutzberg G. Displacement of synaptic terminals from regenerating motoneurons by microglial cells. Z Zellforsch Mikrosk Anat (1968) 85:145-57. doi:10.1007/BF00325030
-
(1968)
Z Zellforsch Mikrosk Anat
, vol.85
, pp. 145-157
-
-
Blinzinger, K.1
Kreutzberg, G.2
-
55
-
-
33846953580
-
Evidence for synaptic stripping by cortical microglia
-
Trapp BD, Wujek JR, Criste GA, Jalabi W, Yin X, Kidd GJ, et al. Evidence for synaptic stripping by cortical microglia. Glia (2007) 55:360-8. doi:10.1002/glia.20462
-
(2007)
Glia
, vol.55
, pp. 360-368
-
-
Trapp, B.D.1
Wujek, J.R.2
Criste, G.A.3
Jalabi, W.4
Yin, X.5
Kidd, G.J.6
-
56
-
-
84919455244
-
Microglial displacement of inhibitory synapses provides neuroprotection in the adult brain
-
Chen Z, Jalabi W, Hu W, Park HJ, Gale JT, Kidd GJ, et al. Microglial displacement of inhibitory synapses provides neuroprotection in the adult brain. Nat Commun (2014) 5:4486. doi:10.1038/ncomms5486
-
(2014)
Nat Commun
, vol.5
, pp. 4486
-
-
Chen, Z.1
Jalabi, W.2
Hu, W.3
Park, H.J.4
Gale, J.T.5
Kidd, G.J.6
-
57
-
-
84884254622
-
Microglia and synapse interactions: fine tuning neural circuits and candidate molecules
-
Miyamoto A, Wake H, Moorhouse AJ, Nabekura J. Microglia and synapse interactions: fine tuning neural circuits and candidate molecules. Front Cell Neurosci (2013) 7:70. doi:10.3389/fncel.2013.00070
-
(2013)
Front Cell Neurosci
, vol.7
, pp. 70
-
-
Miyamoto, A.1
Wake, H.2
Moorhouse, A.J.3
Nabekura, J.4
-
58
-
-
0023893302
-
Macrophages and microglia in the nervous system
-
Perry VH, Gordon S. Macrophages and microglia in the nervous system. Trends Neurosci (1988) 11:273-7. doi:10.1016/0166-2236(88)90110-5
-
(1988)
Trends Neurosci
, vol.11
, pp. 273-277
-
-
Perry, V.H.1
Gordon, S.2
-
59
-
-
0025688161
-
Generation and characterization of monoclonal antibodies against rat microglia and ontogenic distribution of positive cells
-
Imamura K, Ito M, Suzumura A, Asai J, Takahashi A. Generation and characterization of monoclonal antibodies against rat microglia and ontogenic distribution of positive cells. Lab Invest (1990) 63:853-61.
-
(1990)
Lab Invest
, vol.63
, pp. 853-861
-
-
Imamura, K.1
Ito, M.2
Suzumura, A.3
Asai, J.4
Takahashi, A.5
-
60
-
-
0025900245
-
Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system
-
Sedgwick JD, Schwender S, Imrich H, Dorries R, Butcher GW, ter Meulen V. Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system. Proc Natl Acad Sci U S A (1991) 88:7438-42. doi:10.1073/pnas.88.16.7438
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 7438-7442
-
-
Sedgwick, J.D.1
Schwender, S.2
Imrich, H.3
Dorries, R.4
Butcher, G.W.5
ter Meulen, V.6
-
61
-
-
0030601207
-
A novel gene iba1 in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage
-
Imai Y, Ibata I, Ito D, Ohsawa K, Kohsaka S. A novel gene iba1 in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage. Biochem Biophys Res Commun (1996) 224:855-62. doi:10.1006/bbrc.1996.1112
-
(1996)
Biochem Biophys Res Commun
, vol.224
, pp. 855-862
-
-
Imai, Y.1
Ibata, I.2
Ito, D.3
Ohsawa, K.4
Kohsaka, S.5
-
62
-
-
0032102358
-
Microglia-specific localisation of a novel calcium binding protein, Iba1
-
Ito D, Imai Y, Ohsawa K, Nakajima K, Fukuuchi Y, Kohsaka S. Microglia-specific localisation of a novel calcium binding protein, Iba1. Brain Res Mol Brain Res (1998) 57:1-9. doi:10.1016/S0169-328X(98)00040-0
-
(1998)
Brain Res Mol Brain Res
, vol.57
, pp. 1-9
-
-
Ito, D.1
Imai, Y.2
Ohsawa, K.3
Nakajima, K.4
Fukuuchi, Y.5
Kohsaka, S.6
-
63
-
-
0022922108
-
Characterization of ameboid microglia isolated from developing mammalian brain
-
Giulian D, Baker TJ. Characterization of ameboid microglia isolated from developing mammalian brain. J Neurosci (1986) 6:2163-78.
-
(1986)
J Neurosci
, vol.6
, pp. 2163-2178
-
-
Giulian, D.1
Baker, T.J.2
-
64
-
-
0019313317
-
Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue
-
McCarthy KD, de Vellis J. Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J Cell Biol (1980) 85:890-902. doi:10.1083/jcb.85.3.890
-
(1980)
J Cell Biol
, vol.85
, pp. 890-902
-
-
McCarthy, K.D.1
de Vellis, J.2
-
65
-
-
0023740006
-
Characterisation of microglia isolated from adult human and rat brain
-
Hayes GM, Woodroofe MN, Cuzner ML. Characterisation of microglia isolated from adult human and rat brain. J Neuroimmunol (1988) 19:177-89. doi:10.1016/0165-5728(88)90001-X
-
(1988)
J Neuroimmunol
, vol.19
, pp. 177-189
-
-
Hayes, G.M.1
Woodroofe, M.N.2
Cuzner, M.L.3
-
66
-
-
0024587470
-
Immunohistochemical studies of adult human glial cells
-
Grenier Y, Ruijs TC, Robitaille Y, Olivier A, Antel JP. Immunohistochemical studies of adult human glial cells. J Neuroimmunol (1989) 21:103-15. doi:10.1016/0165-5728(89)90166-5
-
(1989)
J Neuroimmunol
, vol.21
, pp. 103-115
-
-
Grenier, Y.1
Ruijs, T.C.2
Robitaille, Y.3
Olivier, A.4
Antel, J.P.5
-
67
-
-
0026484937
-
Characterization of primary human fetal dissociated central nervous system cultures with an emphasis on microglia
-
Lee SC, Liu W, Brosnan CF, Dickson DW. Characterization of primary human fetal dissociated central nervous system cultures with an emphasis on microglia. Lab Invest (1992) 67:465-76.
-
(1992)
Lab Invest
, vol.67
, pp. 465-476
-
-
Lee, S.C.1
Liu, W.2
Brosnan, C.F.3
Dickson, D.W.4
-
68
-
-
0029586077
-
Human microglia cultures: a powerful model to study their origin and immunoreactive capacity
-
Lauro GM, Babiloni D, Buttarelli FR, Starace G, Cocchia D, Ennas MG, et al. Human microglia cultures: a powerful model to study their origin and immunoreactive capacity. Int J Dev Neurosci (1995) 13:739-52. doi:10.1016/0736-5748(95)00059-3
-
(1995)
Int J Dev Neurosci
, vol.13
, pp. 739-752
-
-
Lauro, G.M.1
Babiloni, D.2
Buttarelli, F.R.3
Starace, G.4
Cocchia, D.5
Ennas, M.G.6
-
70
-
-
0027313221
-
Functional roles of microglia in the brain
-
Nakajima K, Kohsaka S. Functional roles of microglia in the brain. Neurosci Res (1993) 17:187-203. doi:10.1016/0168-0102(93)90047-T
-
(1993)
Neurosci Res
, vol.17
, pp. 187-203
-
-
Nakajima, K.1
Kohsaka, S.2
-
71
-
-
0027356280
-
Characterization of brain microglia and the biological significance in the central nervous system
-
Nakajima K, Kohsaka S. Characterization of brain microglia and the biological significance in the central nervous system. Adv Neurol (1993) 60:734-43.
-
(1993)
Adv Neurol
, vol.60
, pp. 734-743
-
-
Nakajima, K.1
Kohsaka, S.2
-
73
-
-
0028589393
-
Surveillance, intervention and cytotoxicity: is there a protective role of microglia
-
Banati RB, Graeber MB. Surveillance, intervention and cytotoxicity: is there a protective role of microglia? Dev Neurosci (1994) 16:114-27. doi:10.1159/000112098
-
(1994)
Dev Neurosci
, vol.16
, pp. 114-127
-
-
Banati, R.B.1
Graeber, M.B.2
-
74
-
-
0028105846
-
Phagocytic microglia release cytokines and cytotoxins that regulate the survival of astrocytes and neurons in culture
-
Giulian D, Li J, Leara B, Keenen C. Phagocytic microglia release cytokines and cytotoxins that regulate the survival of astrocytes and neurons in culture. Neurochem Int (1994) 25:227-33. doi:10.1016/0197-0186(94)90066-3
-
(1994)
Neurochem Int
, vol.25
, pp. 227-233
-
-
Giulian, D.1
Li, J.2
Leara, B.3
Keenen, C.4
-
75
-
-
0032152571
-
Functional roles of microglia in the central nervous system
-
Nakajima K, Kohsaka S. Functional roles of microglia in the central nervous system. Hum Cell (1998) 11:141-55.
-
(1998)
Hum Cell
, vol.11
, pp. 141-155
-
-
Nakajima, K.1
Kohsaka, S.2
-
76
-
-
0034866550
-
Microglia: activation and their significance in the central nervous system
-
Nakajima K, Kohsaka S. Microglia: activation and their significance in the central nervous system. J Biochem (2001) 130:169-75. doi:10.1093/oxfordjournals.jbchem.a002969
-
(2001)
J Biochem
, vol.130
, pp. 169-175
-
-
Nakajima, K.1
Kohsaka, S.2
-
77
-
-
0036849018
-
Microglia as a source and target of cytokines
-
Hanisch UK. Microglia as a source and target of cytokines. Glia (2002) 40:140-55. doi:10.1002/glia.10161
-
(2002)
Glia
, vol.40
, pp. 140-155
-
-
Hanisch, U.K.1
-
78
-
-
1642442424
-
Microglia: neuroprotective and neurotrophic cells in the central nervous system
-
Nakajima K, Kohsaka S. Microglia: neuroprotective and neurotrophic cells in the central nervous system. Curr Drug Targets Cardiovasc Haematol Disord (2004) 4:65-84. doi:10.2174/1568006043481284
-
(2004)
Curr Drug Targets Cardiovasc Haematol Disord
, vol.4
, pp. 65-84
-
-
Nakajima, K.1
Kohsaka, S.2
-
79
-
-
34848843543
-
Neurotransmitter receptors on microglia
-
Pocock JM, Kettenmann H. Neurotransmitter receptors on microglia. Trends Neurosci (2007) 30:527-35. doi:10.1016/j.tins.2007.07.007
-
(2007)
Trends Neurosci
, vol.30
, pp. 527-535
-
-
Pocock, J.M.1
Kettenmann, H.2
-
80
-
-
0024199439
-
Functional plasticity of microglia: a review
-
Streit WJ, Graeber MB, Kreutzberg GW. Functional plasticity of microglia: a review. Glia (1988) 1:301-7. doi:10.1002/glia.440010502
-
(1988)
Glia
, vol.1
, pp. 301-307
-
-
Streit, W.J.1
Graeber, M.B.2
Kreutzberg, G.W.3
-
81
-
-
52049087817
-
Magnetic cell sorting: a fast and effective method of concurrent isolation of high purity viable astrocytes and microglia from neonatal mouse brain tissue
-
Marek R, Caruso M, Rostami A, Grinspan JB, Das Sarma J. Magnetic cell sorting: a fast and effective method of concurrent isolation of high purity viable astrocytes and microglia from neonatal mouse brain tissue. J Neurosci Methods (2008) 175:108-18. doi:10.1016/j.jneumeth.2008.08.016
-
(2008)
J Neurosci Methods
, vol.175
, pp. 108-118
-
-
Marek, R.1
Caruso, M.2
Rostami, A.3
Grinspan, J.B.4
Das Sarma, J.5
-
82
-
-
84859708632
-
An efficient method to limit microglia-dependent effects in astroglial cultures
-
Losciuto S, Dorban G, Gabel S, Gustin A, Hoenen C, Grandbarbe L, et al. An efficient method to limit microglia-dependent effects in astroglial cultures. J Neurosci Methods (2012) 207:59-71. doi:10.1016/j.jneumeth.2012.03.010
-
(2012)
J Neurosci Methods
, vol.207
, pp. 59-71
-
-
Losciuto, S.1
Dorban, G.2
Gabel, S.3
Gustin, A.4
Hoenen, C.5
Grandbarbe, L.6
-
83
-
-
0022401274
-
Selective immortalization of murine macrophages from fresh bone marrow by a raf/myc recombinant murine retrovirus
-
Blasi E, Mathieson BJ, Varesio L, Cleveland JL, Borchert PA, Rapp UR. Selective immortalization of murine macrophages from fresh bone marrow by a raf/myc recombinant murine retrovirus. Nature (1985) 318:667-70. doi:10.1038/318667a0
-
(1985)
Nature
, vol.318
, pp. 667-670
-
-
Blasi, E.1
Mathieson, B.J.2
Varesio, L.3
Cleveland, J.L.4
Borchert, P.A.5
Rapp, U.R.6
-
84
-
-
0025233694
-
Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus
-
Blasi E, Barluzzi R, Bocchini V, Mazzolla R, Bistoni F. Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus. J Neuroimmunol (1990) 27:229-37. doi:10.1016/0165-5728(90)90073-V
-
(1990)
J Neuroimmunol
, vol.27
, pp. 229-237
-
-
Blasi, E.1
Barluzzi, R.2
Bocchini, V.3
Mazzolla, R.4
Bistoni, F.5
-
85
-
-
0024464856
-
Monokine production by microglial cell clones
-
Righi M, Mori L, De Libero G, Sironi M, Biondi A, Mantovani A, et al. Monokine production by microglial cell clones. Eur J Immunol (1989) 19:1443-8. doi:10.1002/eji.1830190815
-
(1989)
Eur J Immunol
, vol.19
, pp. 1443-1448
-
-
Righi, M.1
Mori, L.2
De Libero, G.3
Sironi, M.4
Biondi, A.5
Mantovani, A.6
-
86
-
-
84977614161
-
Transcriptome sequencing reveals that LPS-triggered transcriptional responses in established microglia BV2 cell lines are poorly representative of primary microglia
-
Das A, Kim SH, Arifuzzaman S, Yoon T, Chai JC, Lee YS, et al. Transcriptome sequencing reveals that LPS-triggered transcriptional responses in established microglia BV2 cell lines are poorly representative of primary microglia. J Neuroinflammation (2016) 13:182. doi:10.1186/s12974-016-0644-1
-
(2016)
J Neuroinflammation
, vol.13
, pp. 182
-
-
Das, A.1
Kim, S.H.2
Arifuzzaman, S.3
Yoon, T.4
Chai, J.C.5
Lee, Y.S.6
-
87
-
-
84990845591
-
Characterizing primary human microglia: a comparative study with myeloid subsets and culture models
-
Melief J, Sneeboer MA, Litjens M, Ormel PR, Palmen SJ, Huitinga I, et al. Characterizing primary human microglia: a comparative study with myeloid subsets and culture models. Glia (2016) 64:1857-68. doi:10.1002/glia.23023
-
(2016)
Glia
, vol.64
, pp. 1857-1868
-
-
Melief, J.1
Sneeboer, M.A.2
Litjens, M.3
Ormel, P.R.4
Palmen, S.J.5
Huitinga, I.6
-
88
-
-
0026650620
-
Generation of microglial cell lines by transfection with simian virus 40 large T gene
-
Hosaka Y, Kitamoto A, Shimojo M, Nakajima K, Imai Y, Handa H, et al. Generation of microglial cell lines by transfection with simian virus 40 large T gene. Neurosci Lett (1992) 141:139-42. doi:10.1016/0304-3940(92)90880-G
-
(1992)
Neurosci Lett
, vol.141
, pp. 139-142
-
-
Hosaka, Y.1
Kitamoto, A.2
Shimojo, M.3
Nakajima, K.4
Imai, Y.5
Handa, H.6
-
89
-
-
0029115575
-
Establishment of human microglial cell lines after transfection of primary cultures of embryonic microglial cells with the SV40 large T antigen
-
Janabi N, Peudenier S, Heron B, Ng KH, Tardieu M. Establishment of human microglial cell lines after transfection of primary cultures of embryonic microglial cells with the SV40 large T antigen. Neurosci Lett (1995) 195:105-8. doi:10.1016/0304-3940(94)11792-H
-
(1995)
Neurosci Lett
, vol.195
, pp. 105-108
-
-
Janabi, N.1
Peudenier, S.2
Heron, B.3
Ng, K.H.4
Tardieu, M.5
-
90
-
-
0029563373
-
Mouse microglial cell lines differing in constitutive and interferon-gamma-inducible antigen-presenting activities for naive and memory CD4+ and CD8+ T cells
-
Walker WS, Gatewood J, Olivas E, Askew D, Havenith CE. Mouse microglial cell lines differing in constitutive and interferon-gamma-inducible antigen-presenting activities for naive and memory CD4+ and CD8+ T cells. J Neuroimmunol (1995) 63:163-74. doi:10.1016/0165-5728(95)00146-8
-
(1995)
J Neuroimmunol
, vol.63
, pp. 163-174
-
-
Walker, W.S.1
Gatewood, J.2
Olivas, E.3
Askew, D.4
Havenith, C.E.5
-
91
-
-
0030595007
-
A spontaneously immortalized mouse microglial cell line expressing CD4
-
Alliot F, Marty MC, Cambier D, Pessac B. A spontaneously immortalized mouse microglial cell line expressing CD4. Brain Res Dev Brain Res (1996) 95:140-3. doi:10.1016/0165-3806(96)00101-0
-
(1996)
Brain Res Dev Brain Res
, vol.95
, pp. 140-143
-
-
Alliot, F.1
Marty, M.C.2
Cambier, D.3
Pessac, B.4
-
92
-
-
0031282491
-
Generation and characterization of a microglial cell line, MG5, derived from a p53-deficient mouse
-
Ohsawa K, Imai Y, Nakajima K, Kohsaka S. Generation and characterization of a microglial cell line, MG5, derived from a p53-deficient mouse. Glia (1997) 21:285-98. doi:10.1002/(SICI)1098-1136(199711)21:3<285::AID-GLIA4>3.3.CO;2-1
-
(1997)
Glia
, vol.21
, pp. 285-298
-
-
Ohsawa, K.1
Imai, Y.2
Nakajima, K.3
Kohsaka, S.4
-
93
-
-
0031748533
-
HERG-like K+ channels in microglia
-
Zhou W, Cayabyab FS, Pennefather PS, Schlichter LC, DeCoursey TE. HERG-like K+ channels in microglia. J Gen Physiol (1998) 111:781-94. doi:10.1085/jgp.111.6.781
-
(1998)
J Gen Physiol
, vol.111
, pp. 781-794
-
-
Zhou, W.1
Cayabyab, F.S.2
Pennefather, P.S.3
Schlichter, L.C.4
DeCoursey, T.E.5
-
94
-
-
0031840591
-
Brain-specific gene expression by immortalized microglial cell-mediated gene transfer in the mammalian brain
-
Sawada M, Imai F, Suzuki H, Hayakawa M, Kanno T, Nagatsu T. Brain-specific gene expression by immortalized microglial cell-mediated gene transfer in the mammalian brain. FEBS Lett (1998) 433:37-40. doi:10.1016/S0014-5793(98)00879-5
-
(1998)
FEBS Lett
, vol.433
, pp. 37-40
-
-
Sawada, M.1
Imai, F.2
Suzuki, H.3
Hayakawa, M.4
Kanno, T.5
Nagatsu, T.6
-
95
-
-
0034959741
-
Characterization of a novel brain-derived microglial cell line isolated from neonatal rat brain
-
Cheepsunthorn P, Radov L, Menzies S, Reid J, Connor JR. Characterization of a novel brain-derived microglial cell line isolated from neonatal rat brain. Glia (2001) 35:53-62. doi:10.1002/glia.1070
-
(2001)
Glia
, vol.35
, pp. 53-62
-
-
Cheepsunthorn, P.1
Radov, L.2
Menzies, S.3
Reid, J.4
Connor, J.R.5
-
96
-
-
0035660771
-
Generation and characterization of immortalized human microglial cell lines: expression of cytokines and chemokines
-
Nagai A, Nakagawa E, Hatori K, Choi HB, McLarnon JG, Lee MA, et al. Generation and characterization of immortalized human microglial cell lines: expression of cytokines and chemokines. Neurobiol Dis (2001) 8:1057-68. doi:10.1006/nbdi.2001.0437
-
(2001)
Neurobiol Dis
, vol.8
, pp. 1057-1068
-
-
Nagai, A.1
Nakagawa, E.2
Hatori, K.3
Choi, H.B.4
McLarnon, J.G.5
Lee, M.A.6
-
97
-
-
27644520207
-
Inhibitory effects of U73122 and U73343 on Ca2+ influx and pore formation induced by the activation of P2X7 nucleotide receptors in mouse microglial cell line
-
Takenouchi T, Ogihara K, Sato M, Kitani H. Inhibitory effects of U73122 and U73343 on Ca2+ influx and pore formation induced by the activation of P2X7 nucleotide receptors in mouse microglial cell line. Biochim Biophys Acta (2005) 1726:177-86. doi:10.1016/j.bbagen.2005.08.001
-
(2005)
Biochim Biophys Acta
, vol.1726
, pp. 177-186
-
-
Takenouchi, T.1
Ogihara, K.2
Sato, M.3
Kitani, H.4
-
98
-
-
84903904211
-
A novel cell line from spontaneously immortalized murine microglia
-
Nagamoto-Combs K, Kulas J, Combs CK. A novel cell line from spontaneously immortalized murine microglia. J Neurosci Methods (2014) 233:187-98. doi:10.1016/j.jneumeth.2014.05.021
-
(2014)
J Neurosci Methods
, vol.233
, pp. 187-198
-
-
Nagamoto-Combs, K.1
Kulas, J.2
Combs, C.K.3
-
99
-
-
84955265262
-
Characterization of a novel adult murine immortalized microglial cell line and its activation by amyloid-beta
-
McCarthy RC, Lu DY, Alkhateeb A, Gardeck AM, Lee CH, Wessling-Resnick M. Characterization of a novel adult murine immortalized microglial cell line and its activation by amyloid-beta. J Neuroinflammation (2016) 13:21. doi:10.1186/s12974-016-0484-z
-
(2016)
J Neuroinflammation
, vol.13
, pp. 21
-
-
McCarthy, R.C.1
Lu, D.Y.2
Alkhateeb, A.3
Gardeck, A.M.4
Lee, C.H.5
Wessling-Resnick, M.6
-
100
-
-
13844292402
-
Characterization of microglia induced from mouse embryonic stem cells and their migration into the brain parenchyma
-
Tsuchiya T, Park KC, Toyonaga S, Yamada SM, Nakabayashi H, Nakai E, et al. Characterization of microglia induced from mouse embryonic stem cells and their migration into the brain parenchyma. J Neuroimmunol (2005) 160:210-8. doi:10.1016/j.jneuroim.2004.10.025
-
(2005)
J Neuroimmunol
, vol.160
, pp. 210-218
-
-
Tsuchiya, T.1
Park, K.C.2
Toyonaga, S.3
Yamada, S.M.4
Nakabayashi, H.5
Nakai, E.6
-
101
-
-
0034044317
-
Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells
-
Lee SH, Lumelsky N, Studer L, Auerbach JM, McKay RD. Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells. Nat Biotechnol (2000) 18:675-9. doi:10.1038/76536
-
(2000)
Nat Biotechnol
, vol.18
, pp. 675-679
-
-
Lee, S.H.1
Lumelsky, N.2
Studer, L.3
Auerbach, J.M.4
McKay, R.D.5
-
102
-
-
0027389676
-
Hematopoietic commitment during embryonic stem cell differentiation in culture
-
Keller G, Kennedy M, Papayannopoulou T, Wiles MV. Hematopoietic commitment during embryonic stem cell differentiation in culture. Mol Cell Biol (1993) 13:473-86. doi:10.1128/MCB.13.1.473
-
(1993)
Mol Cell Biol
, vol.13
, pp. 473-486
-
-
Keller, G.1
Kennedy, M.2
Papayannopoulou, T.3
Wiles, M.V.4
-
103
-
-
70449668939
-
Microglial precursors derived from mouse embryonic stem cells
-
Napoli I, Kierdorf K, Neumann H. Microglial precursors derived from mouse embryonic stem cells. Glia (2009) 57:1660-71. doi:10.1002/glia.20878
-
(2009)
Glia
, vol.57
, pp. 1660-1671
-
-
Napoli, I.1
Kierdorf, K.2
Neumann, H.3
-
104
-
-
77955908261
-
Generation of microglial cells from mouse embryonic stem cells
-
Beutner C, Roy K, Linnartz B, Napoli I, Neumann H. Generation of microglial cells from mouse embryonic stem cells. Nat Protoc (2010) 5:1481-94. doi:10.1038/nprot.2010.90
-
(2010)
Nat Protoc
, vol.5
, pp. 1481-1494
-
-
Beutner, C.1
Roy, K.2
Linnartz, B.3
Napoli, I.4
Neumann, H.5
-
105
-
-
84988689034
-
Efficient derivation of microglia-like cells from human pluripotent stem cells
-
Muffat J, Li Y, Yuan B, Mitalipova M, Omer A, Corcoran S, et al. Efficient derivation of microglia-like cells from human pluripotent stem cells. Nat Med (2016) 22:1358-67. doi:10.1038/nm.4189
-
(2016)
Nat Med
, vol.22
, pp. 1358-1367
-
-
Muffat, J.1
Li, Y.2
Yuan, B.3
Mitalipova, M.4
Omer, A.5
Corcoran, S.6
-
106
-
-
0034028817
-
Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion
-
Jung S, Aliberti J, Graemmel P, Sunshine MJ, Kreutzberg GW, Sher A, et al. Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol Cell Biol (2000) 20:4106-14. doi:10.1128/MCB.20.11.4106-4114.2000
-
(2000)
Mol Cell Biol
, vol.20
, pp. 4106-4114
-
-
Jung, S.1
Aliberti, J.2
Graemmel, P.3
Sunshine, M.J.4
Kreutzberg, G.W.5
Sher, A.6
-
107
-
-
84963841577
-
Origin, fate and dynamics of macrophages at central nervous system interfaces
-
Goldmann T, Wieghofer P, Jordao MJ, Prutek F, Hagemeyer N, Frenzel K, et al. Origin, fate and dynamics of macrophages at central nervous system interfaces. Nat Immunol (2016) 17:797-805. doi:10.1038/ni.3423
-
(2016)
Nat Immunol
, vol.17
, pp. 797-805
-
-
Goldmann, T.1
Wieghofer, P.2
Jordao, M.J.3
Prutek, F.4
Hagemeyer, N.5
Frenzel, K.6
-
108
-
-
33745573660
-
Control of microglial neurotoxicity by the fractalkine receptor
-
Cardona AE, Pioro EP, Sasse ME, Kostenko V, Cardona SM, Dijkstra IM, et al. Control of microglial neurotoxicity by the fractalkine receptor. Nat Neurosci (2006) 9:917-24. doi:10.1038/nn1715
-
(2006)
Nat Neurosci
, vol.9
, pp. 917-924
-
-
Cardona, A.E.1
Pioro, E.P.2
Sasse, M.E.3
Kostenko, V.4
Cardona, S.M.5
Dijkstra, I.M.6
-
109
-
-
25444469608
-
Visualization of microglia in living tissues using Iba1-EGFP transgenic mice
-
Hirasawa T, Ohsawa K, Imai Y, Ondo Y, Akazawa C, Uchino S, et al. Visualization of microglia in living tissues using Iba1-EGFP transgenic mice. J Neurosci Res (2005) 81:357-62. doi:10.1002/jnr.20480
-
(2005)
J Neurosci Res
, vol.81
, pp. 357-362
-
-
Hirasawa, T.1
Ohsawa, K.2
Imai, Y.3
Ondo, Y.4
Akazawa, C.5
Uchino, S.6
-
110
-
-
84875932665
-
Microglia, seen from the CX3CR1 angle
-
Wolf Y, Yona S, Kim KW, Jung S. Microglia, seen from the CX3CR1 angle. Front Cell Neurosci (2013) 7:26. doi:10.3389/fncel.2013.00026
-
(2013)
Front Cell Neurosci
, vol.7
, pp. 26
-
-
Wolf, Y.1
Yona, S.2
Kim, K.W.3
Jung, S.4
-
111
-
-
84911388342
-
Genetic targeting of microglia
-
Wieghofer P, Knobeloch KP, Prinz M. Genetic targeting of microglia. Glia (2015) 63:1-22. doi:10.1002/glia.22727
-
(2015)
Glia
, vol.63
, pp. 1-22
-
-
Wieghofer, P.1
Knobeloch, K.P.2
Prinz, M.3
-
112
-
-
0019725433
-
Organotypic monolayer cultures of nervous tissue
-
Gahwiler BH. Organotypic monolayer cultures of nervous tissue. J Neurosci Methods (1981) 4:329-42. doi:10.1016/0165-0270(81)90003-0
-
(1981)
J Neurosci Methods
, vol.4
, pp. 329-342
-
-
Gahwiler, B.H.1
-
113
-
-
0025805120
-
A simple method for organotypic cultures of nervous tissue
-
Stoppini L, Buchs PA, Muller D. A simple method for organotypic cultures of nervous tissue. J Neurosci Methods (1991) 37:173-82. doi:10.1016/0165-0270(91)90128-M
-
(1991)
J Neurosci Methods
, vol.37
, pp. 173-182
-
-
Stoppini, L.1
Buchs, P.A.2
Muller, D.3
-
114
-
-
84856349219
-
Neuroprotective function for ramified microglia in hippocampal excitotoxicity
-
Vinet J, Weering HR, Heinrich A, Kalin RE, Wegner A, Brouwer N, et al. Neuroprotective function for ramified microglia in hippocampal excitotoxicity. J Neuroinflammation (2012) 9:27. doi:10.1186/1742-2094-9-27
-
(2012)
J Neuroinflammation
, vol.9
, pp. 27
-
-
Vinet, J.1
Weering, H.R.2
Heinrich, A.3
Kalin, R.E.4
Wegner, A.5
Brouwer, N.6
-
115
-
-
84975275555
-
Microglia replenished OHSC: a culture system to study in vivo like adult microglia
-
Masuch A, van der Pijl R, Funer L, Wolf Y, Eggen B, Boddeke E, et al. Microglia replenished OHSC: a culture system to study in vivo like adult microglia. Glia (2016) 64:1285-97. doi:10.1002/glia.23002
-
(2016)
Glia
, vol.64
, pp. 1285-1297
-
-
Masuch, A.1
van der Pijl, R.2
Funer, L.3
Wolf, Y.4
Eggen, B.5
Boddeke, E.6
-
116
-
-
84979737421
-
Age-related myelin degradation burdens the clearance function of microglia during aging
-
Safaiyan S, Kannaiyan N, Snaidero N, Brioschi S, Biber K, Yona S, et al. Age-related myelin degradation burdens the clearance function of microglia during aging. Nat Neurosci (2016) 19:995-8. doi:10.1038/nn.4325
-
(2016)
Nat Neurosci
, vol.19
, pp. 995-998
-
-
Safaiyan, S.1
Kannaiyan, N.2
Snaidero, N.3
Brioschi, S.4
Biber, K.5
Yona, S.6
-
117
-
-
84957850437
-
Genetic manipulation of microglia during brain development and disease
-
Wieghofer P, Prinz M. Genetic manipulation of microglia during brain development and disease. Biochim Biophys Acta (2016) 1862:299-309. doi:10.1016/j.bbadis.2015.09.019
-
(2016)
Biochim Biophys Acta
, vol.1862
, pp. 299-309
-
-
Wieghofer, P.1
Prinz, M.2
-
118
-
-
0004113253
-
-
A Guide for the Laboratory Use of Zebrafish (Danio Rerio). Eugene, OR: University of Oregon Press
-
Westerfield M. The Zebrafish Book. A Guide for the Laboratory Use of Zebrafish (Danio Rerio). Eugene, OR: University of Oregon Press (2000).
-
(2000)
The Zebrafish Book
-
-
Westerfield, M.1
-
119
-
-
84869162083
-
Animal models for studying microglia: the first, the popular, and the new
-
Sieger D, Peri F. Animal models for studying microglia: the first, the popular, and the new. Glia (2013) 61:3-9. doi:10.1002/glia.22385
-
(2013)
Glia
, vol.61
, pp. 3-9
-
-
Sieger, D.1
Peri, F.2
-
120
-
-
43949088191
-
Live imaging of neuronal degradation by microglia reveals a role for v0-ATPase a1 in phagosomal fusion in vivo
-
Peri F, Nusslein-Volhard C. Live imaging of neuronal degradation by microglia reveals a role for v0-ATPase a1 in phagosomal fusion in vivo. Cell (2008) 133:916-27. doi:10.1016/j.cell.2008.04.037
-
(2008)
Cell
, vol.133
, pp. 916-927
-
-
Peri, F.1
Nusslein-Volhard, C.2
-
121
-
-
84859508307
-
A lineage of myeloid cells independent of Myb and hematopoietic stem cells
-
Schulz C, Gomez Perdiguero E, Chorro L, Szabo-Rogers H, Cagnard N, Kierdorf K, et al. A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science (2012) 336:86-90. doi:10.1126/science.1219179
-
(2012)
Science
, vol.336
, pp. 86-90
-
-
Schulz, C.1
Gomez Perdiguero, E.2
Chorro, L.3
Szabo-Rogers, H.4
Cagnard, N.5
Kierdorf, K.6
-
122
-
-
34247601504
-
Cell tracing shows the contribution of the yolk sac to adult haematopoiesis
-
Samokhvalov IM, Samokhvalova NI, Nishikawa S. Cell tracing shows the contribution of the yolk sac to adult haematopoiesis. Nature (2007) 446:1056-61. doi:10.1038/nature05725
-
(2007)
Nature
, vol.446
, pp. 1056-1061
-
-
Samokhvalov, I.M.1
Samokhvalova, N.I.2
Nishikawa, S.3
-
123
-
-
84957554443
-
Fate mapping reveals that microglia and recruited monocyte-derived macrophages are definitively distinguishable by phenotype in the retina
-
O'Koren EG, Mathew R, Saban DR. Fate mapping reveals that microglia and recruited monocyte-derived macrophages are definitively distinguishable by phenotype in the retina. Sci Rep (2016) 6:20636. doi:10.1038/srep20636
-
(2016)
Sci Rep
, vol.6
, pp. 20636
-
-
O'Koren, E.G.1
Mathew, R.2
Saban, D.R.3
-
124
-
-
85002972264
-
Perivascular macrophages mediate the neurovascular and cognitive dysfunction associated with hypertension
-
Faraco G, Sugiyama Y, Lane D, Garcia-Bonilla L, Chang H, Santisteban MM, et al. Perivascular macrophages mediate the neurovascular and cognitive dysfunction associated with hypertension. J Clin Invest (2016) 126:4674-89. doi:10.1172/JCI86950
-
(2016)
J Clin Invest
, vol.126
, pp. 4674-4689
-
-
Faraco, G.1
Sugiyama, Y.2
Lane, D.3
Garcia-Bonilla, L.4
Chang, H.5
Santisteban, M.M.6
-
125
-
-
84988706183
-
Infiltrating monocytes promote brain inflammation and exacerbate neuronal damage after status epilepticus
-
Varvel NH, Neher JJ, Bosch A, Wang W, Ransohoff RM, Miller RJ, et al. Infiltrating monocytes promote brain inflammation and exacerbate neuronal damage after status epilepticus. Proc Natl Acad Sci U S A (2016) 113:E5665-74. doi:10.1073/pnas.1604263113
-
(2016)
Proc Natl Acad Sci U S A
, vol.113
, pp. E5665-E5674
-
-
Varvel, N.H.1
Neher, J.J.2
Bosch, A.3
Wang, W.4
Ransohoff, R.M.5
Miller, R.J.6
-
126
-
-
85003605084
-
P2Y12 receptor is expressed on human microglia under physiological conditions throughout development and is sensitive to neuroinflammatory diseases
-
Mildner A, Huang H, Radke J, Stenzel W, Priller J. P2Y12 receptor is expressed on human microglia under physiological conditions throughout development and is sensitive to neuroinflammatory diseases. Glia (2016) 65(2):375-87. doi:10.1002/glia.23097
-
(2016)
Glia
, vol.65
, Issue.2
, pp. 375-387
-
-
Mildner, A.1
Huang, H.2
Radke, J.3
Stenzel, W.4
Priller, J.5
-
127
-
-
84942522549
-
Homeostasis of microglia in the adult brain: review of novel microglia depletion systems
-
Waisman A, Ginhoux F, Greter M, Bruttger J. Homeostasis of microglia in the adult brain: review of novel microglia depletion systems. Trends Immunol (2015) 36:625-36. doi:10.1016/j.it.2015.08.005
-
(2015)
Trends Immunol
, vol.36
, pp. 625-636
-
-
Waisman, A.1
Ginhoux, F.2
Greter, M.3
Bruttger, J.4
-
128
-
-
84880768767
-
Unique transcriptome signature of mouse microglia
-
Beutner C, Linnartz-Gerlach B, Schmidt SV, Beyer M, Mallmann MR, Staratschek-Jox A, et al. Unique transcriptome signature of mouse microglia. Glia (2013) 61:1429-42. doi:10.1002/glia.22524
-
(2013)
Glia
, vol.61
, pp. 1429-1442
-
-
Beutner, C.1
Linnartz-Gerlach, B.2
Schmidt, S.V.3
Beyer, M.4
Mallmann, M.R.5
Staratschek-Jox, A.6
-
129
-
-
84933043202
-
Host microbiota constantly control maturation and function of microglia in the CNS
-
Erny D, de Angelis Hrabe AL, Jaitin D, Wieghofer P, Staszewski O, David E, et al. Host microbiota constantly control maturation and function of microglia in the CNS. Nat Neurosci (2015) 18:965-77. doi:10.1038/nn.4030
-
(2015)
Nat Neurosci
, vol.18
, pp. 965-977
-
-
Erny, D.1
de Angelis Hrabe, A.L.2
Jaitin, D.3
Wieghofer, P.4
Staszewski, O.5
David, E.6
-
130
-
-
84976883162
-
Microglia development follows a stepwise program to regulate brain homeostasis
-
Matcovitch-Natan O, Winter DR, Giladi A, Vargas Aguilar S, Spinrad A, Sarrazin S, et al. Microglia development follows a stepwise program to regulate brain homeostasis. Science (2016) 353:aad8670. doi:10.1126/science.aad8670
-
(2016)
Science
, vol.353
-
-
Matcovitch-Natan, O.1
Winter, D.R.2
Giladi, A.3
Vargas Aguilar, S.4
Spinrad, A.5
Sarrazin, S.6
-
131
-
-
84960388165
-
Microglial physiology and pathophysiology: insights from genome-wide transcriptional profiling
-
Crotti A, Ransohoff RM. Microglial physiology and pathophysiology: insights from genome-wide transcriptional profiling. Immunity (2016) 44:505-15. doi:10.1016/j.immuni.2016.02.013
-
(2016)
Immunity
, vol.44
, pp. 505-515
-
-
Crotti, A.1
Ransohoff, R.M.2
-
132
-
-
84953840062
-
Next generation transcriptomics and genomics elucidate biological complexity of microglia in health and disease
-
Wes PD, Holtman IR, Boddeke EW, Moller T, Eggen BJ. Next generation transcriptomics and genomics elucidate biological complexity of microglia in health and disease. Glia (2016) 64:197-213. doi:10.1002/glia.22866
-
(2016)
Glia
, vol.64
, pp. 197-213
-
-
Wes, P.D.1
Holtman, I.R.2
Boddeke, E.W.3
Moller, T.4
Eggen, B.J.5
-
133
-
-
84948762727
-
Glia open access database (GOAD): a comprehensive gene expression encyclopedia of glia cells in health and disease
-
Holtman IR, Noback M, Bijlsma M, Duong KN, van der Geest MA, Ketelaars PT, et al. Glia open access database (GOAD): a comprehensive gene expression encyclopedia of glia cells in health and disease. Glia (2015) 63:1495-506. doi:10.1002/glia.22810
-
(2015)
Glia
, vol.63
, pp. 1495-1506
-
-
Holtman, I.R.1
Noback, M.2
Bijlsma, M.3
Duong, K.N.4
van der Geest, M.A.5
Ketelaars, P.T.6
-
134
-
-
84926315282
-
The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems
-
Carabotti M, Scirocco A, Maselli MA, Severi C. The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems. Ann Gastroenterol (2015) 28:203-9.
-
(2015)
Ann Gastroenterol
, vol.28
, pp. 203-209
-
-
Carabotti, M.1
Scirocco, A.2
Maselli, M.A.3
Severi, C.4
-
135
-
-
84905024841
-
Can we talk about microglia without neurons? A discussion of microglial cell autonomous properties in culture
-
Neiva I, Malva JO, Valero J. Can we talk about microglia without neurons? A discussion of microglial cell autonomous properties in culture. Front Cell Neurosci (2014) 8:202. doi:10.3389/fncel.2014.00202
-
(2014)
Front Cell Neurosci
, vol.8
, pp. 202
-
-
Neiva, I.1
Malva, J.O.2
Valero, J.3
-
136
-
-
84959110290
-
Microglial brain region-dependent diversity and selective regional sensitivities to aging
-
Grabert K, Michoel T, Karavolos MH, Clohisey S, Baillie JK, Stevens MP, et al. Microglial brain region-dependent diversity and selective regional sensitivities to aging. Nat Neurosci (2016) 19:504-16. doi:10.1038/nn.4222
-
(2016)
Nat Neurosci
, vol.19
, pp. 504-516
-
-
Grabert, K.1
Michoel, T.2
Karavolos, M.H.3
Clohisey, S.4
Baillie, J.K.5
Stevens, M.P.6
-
137
-
-
84939618789
-
Brain region-specific gene expression profiles in freshly isolated rat microglia
-
Doorn KJ, Breve JJ, Drukarch B, Boddeke HW, Huitinga I, Lucassen PJ, et al. Brain region-specific gene expression profiles in freshly isolated rat microglia. Front Cell Neurosci (2015) 9:84. doi:10.3389/fncel.2015.00084
-
(2015)
Front Cell Neurosci
, vol.9
, pp. 84
-
-
Doorn, K.J.1
Breve, J.J.2
Drukarch, B.3
Boddeke, H.W.4
Huitinga, I.5
Lucassen, P.J.6
-
138
-
-
84991670933
-
Identification of a conserved and acute neurodegeneration-specific microglial transcriptome in the zebrafish
-
Oosterhof N, Holtman IR, Kuil LE, van der Linde HC, Boddeke EW, Eggen BJ, et al. Identification of a conserved and acute neurodegeneration-specific microglial transcriptome in the zebrafish. Glia (2016) 65(1):138-49. doi:10.1002/glia.23083
-
(2016)
Glia
, vol.65
, Issue.1
, pp. 138-149
-
-
Oosterhof, N.1
Holtman, I.R.2
Kuil, L.E.3
van der Linde, H.C.4
Boddeke, E.W.5
Eggen, B.J.6
-
139
-
-
84955712112
-
TMEM119 marks a subset of microglia in the human brain
-
Satoh J, Kino Y, Asahina N, Takitani M, Miyoshi J, Ishida T, et al. TMEM119 marks a subset of microglia in the human brain. Neuropathology (2016) 36:39-49. doi:10.1111/neup.12235
-
(2016)
Neuropathology
, vol.36
, pp. 39-49
-
-
Satoh, J.1
Kino, Y.2
Asahina, N.3
Takitani, M.4
Miyoshi, J.5
Ishida, T.6
-
140
-
-
84957840860
-
Central nervous system myeloid cells as drug targets: current status and translational challenges
-
Biber K, Moller T, Boddeke E, Prinz M. Central nervous system myeloid cells as drug targets: current status and translational challenges. Nat Rev Drug Discov (2016) 15:110-24. doi:10.1038/nrd.2015.14
-
(2016)
Nat Rev Drug Discov
, vol.15
, pp. 110-124
-
-
Biber, K.1
Moller, T.2
Boddeke, E.3
Prinz, M.4
-
141
-
-
84931274624
-
A survey of human brain transcriptome diversity at the single cell level
-
Darmanis S, Sloan SA, Zhang Y, Enge M, Caneda C, Shuer LM, et al. A survey of human brain transcriptome diversity at the single cell level. Proc Natl Acad Sci U S A (2015) 112:7285-90. doi:10.1073/pnas.1507125112
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. 7285-7290
-
-
Darmanis, S.1
Sloan, S.A.2
Zhang, Y.3
Enge, M.4
Caneda, C.5
Shuer, L.M.6
-
142
-
-
84924565530
-
Brain structure. Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq
-
Zeisel A, Munoz-Manchado AB, Codeluppi S, Lonnerberg P, La Manno G, Jureus A, et al. Brain structure. Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq. Science (2015) 347:1138-42. doi:10.1126/science.aaa1934
-
(2015)
Science
, vol.347
, pp. 1138-1142
-
-
Zeisel, A.1
Munoz-Manchado, A.B.2
Codeluppi, S.3
Lonnerberg, P.4
La Manno, G.5
Jureus, A.6
-
143
-
-
84961327715
-
Adult mouse cortical cell taxonomy revealed by single cell transcriptomics
-
Tasic B, Menon V, Nguyen TN, Kim TK, Jarsky T, Yao Z, et al. Adult mouse cortical cell taxonomy revealed by single cell transcriptomics. Nat Neurosci (2016) 19:335-46. doi:10.1038/nn.4216
-
(2016)
Nat Neurosci
, vol.19
, pp. 335-346
-
-
Tasic, B.1
Menon, V.2
Nguyen, T.N.3
Kim, T.K.4
Jarsky, T.5
Yao, Z.6
|