Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1

PLoS ONE

Volumn 10, Issue 2, 2015, Pages

  Szulzewsky, Frank ^a   Pelz, Andreas ^a,b   Feng, Xi ^c   Synowitz, Michael ^a,b   Markovic, Darko ^a,e   Langmann, Thomas ^f   Holtman, Inge R ^g   Wang, Xi ^a   Eggen, Bart J L ^g   Boddeke, Hendrikus W G M ^g   Hambardzumyan, Dolores ^c,d   Wolf, Susanne A ^a   Kettenmann, Helmut ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c LERNER RESEARCH INSTITUTE   (United States)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e HELIOS Clinic   (Germany)

^f UNIVERSITY OF COLOGNE   (Germany)

^g UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; GPNMB PROTEIN, HUMAN; MEMBRANE PROTEIN; OSTEOPONTIN; SPP1 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN TUMOR; CANCER PROGNOSIS; CANCER SURVIVAL; CHICKEN; CONTROLLED STUDY; DOWN REGULATION; GENE; GENE EXPRESSION; GLIOBLASTOMA; GLIOMA; GLIOMA ASSOCIATED MACROPHAGE; GLIOMA ASSOCIATED MICROGLIA; GPNMB GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MICROGLIA; MOUSE; NONHUMAN; PHENOTYPE; SPP1 GENE; UPREGULATION; ANIMAL; CANCER TRANSPLANTATION; CELL CULTURE; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; PROGNOSIS; TUMOR CELL LINE;

MURINAE;

ANIMALS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELLS, CULTURED; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOBLASTOMA; HUMANS; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MICE; MICROGLIA; NEOPLASM TRANSPLANTATION; OSTEOPONTIN; PROGNOSIS;

EID: 84922658111     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0116644     Document Type: Article

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