Perivascular macrophages mediate the neurovascular and cognitive dysfunction associated with hypertension

Journal of Clinical Investigation

Volumn 126, Issue 12, 2016, Pages 4674-4689

  Faraco, Giuseppe ^a   Sugiyama, Yukio ^a   Lane, Diane ^a   Garcia Bonilla, Lidia ^a   Chang, Haejoo ^a   Santisteban, Monica M ^a   Racchumi, Gianfranco ^a   Murphy, Michelle ^a   Van Rooijen, Nico ^b   Anrather, Joseph ^a   Iadecola, Costantino ^a  

^a FEIL FAMILY BRAIN AND MIND RESEARCH INSTITUTE   (United States)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; CYBB PROTEIN, MOUSE; MEMBRANE PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BARNES MAZE TEST; BLOOD BRAIN BARRIER; BONE MARROW CELL; BRAIN BLOOD VESSEL; BRAIN VENTRICLE; COGNITION; COGNITIVE DEFECT; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DISEASE ASSOCIATION; ELECTRON MICROSCOPY; ESSENTIAL HYPERTENSION; HYPERTENSION; MACROPHAGE; MALE; MICROGLIA; MOUSE; NONHUMAN; NOVEL OBJECT RECOGNITION TEST; OXIDATIVE STRESS; PATHOGENESIS; PERIVASCULAR MACROPHAGE; PERIVASCULAR SPACE; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN DEPLETION; REGULATORY MECHANISM; SOMATOSENSORY CORTEX; SPATIAL LEARNING; SPATIAL MEMORY; VASCULAR DISEASE; ANIMAL; COGNITIVE DYSFUNCTION; COMPLICATION; DISEASE MODEL; GENETICS; METABOLISM; PATHOLOGY;

ANGIOTENSIN II; ANIMALS; BLOOD-BRAIN BARRIER; COGNITIVE DYSFUNCTION; DISEASE MODELS, ANIMAL; HYPERTENSION; MACROPHAGES; MALE; MEMBRANE GLYCOPROTEINS; MICE; NADPH OXIDASE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RECEPTOR, ANGIOTENSIN, TYPE 1;

EID: 85002972264     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI86950     Document Type: Article

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