Crystal structure and dynamics of a lipid-induced potential desensitized-state of a pentameric ligand-gated channel

eLife

Volumn 6, Issue , 2017, Pages

  Basak, Sandip ^a   Schmandt, Nicolaus ^a,b   Gicheru, Yvonne ^a   Chakrapani, Sudha ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOCOSAHEXAENOIC ACID; LIGAND GATED ION CHANNEL; MALTOSE BINDING PROTEIN; MSP1E3D1 PROTEIN; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL TISSUE; ARTICLE; CHEMICAL BINDING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; DESENSITIZATION; ELECTRON SPIN RESONANCE; ELECTROPHYSIOLOGY; MEMBRANE RECONSTITUTION; MOLECULAR CLONING; NONHUMAN; OOCYTE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN EXPRESSION; SPIN LABELING; VOLTAGE CLAMP TECHNIQUE; X RAY DIFFRACTION; XENOPUS LAEVIS; CHEMISTRY; METABOLISM; MOLECULAR MODEL; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; DOCOSAHEXAENOIC ACIDS; LIGAND-GATED ION CHANNELS; MODELS, MOLECULAR; PROTEIN CONFORMATION;

EID: 85017094287     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.23886     Document Type: Article

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