-
1
-
-
0031870973
-
Desensitization of mouse nicotinic acetylcholine receptor channels. A two-gate mechanism
-
A. Auerbach, and G. Akk Desensitization of mouse nicotinic acetylcholine receptor channels. A two-gate mechanism J. Gen. Physiol. 112 1998 181 197
-
(1998)
J. Gen. Physiol.
, vol.112
, pp. 181-197
-
-
Auerbach, A.1
Akk, G.2
-
2
-
-
84865723813
-
Optimization of the additive CHARMM all-atom protein force field targeting improved sampling of the backbone phi, psi and side-chain chi(1) and chi(2) dihedral angles
-
R.B. Best, X. Zhu, J. Shim, P.E. Lopes, J. Mittal, M. Feig, and A.D. Mackerell Jr. Optimization of the additive CHARMM all-atom protein force field targeting improved sampling of the backbone phi, psi and side-chain chi(1) and chi(2) dihedral angles J. Chem. Theor. Comput. 8 2012 3257 3273
-
(2012)
J. Chem. Theor. Comput.
, vol.8
, pp. 3257-3273
-
-
Best, R.B.1
Zhu, X.2
Shim, J.3
Lopes, P.E.4
Mittal, J.5
Feig, M.6
Mackerell, A.D.7
-
3
-
-
58149267953
-
X-Ray structure of a pentameric ligand-gated ion channel in an apparently open conformation
-
N. Bocquet, H. Nury, M. Baaden, C. Le Poupon, J.P. Changeux, M. Delarue, and P.J. Corringer X-Ray structure of a pentameric ligand-gated ion channel in an apparently open conformation Nature 457 2009 111 114
-
(2009)
Nature
, vol.457
, pp. 111-114
-
-
Bocquet, N.1
Nury, H.2
Baaden, M.3
Le Poupon, C.4
Changeux, J.P.5
Delarue, M.6
Corringer, P.J.7
-
4
-
-
84862830755
-
NMR structures of the transmembrane domains of the alpha4beta2 nAChR
-
V. Bondarenko, D. Mowrey, T. Tillman, T. Cui, L.T. Liu, Y. Xu, and P. Tang NMR structures of the transmembrane domains of the alpha4beta2 nAChR Biochim. Biophys. Acta 1818 2012 1261 1268
-
(2012)
Biochim. Biophys. Acta
, vol.1818
, pp. 1261-1268
-
-
Bondarenko, V.1
Mowrey, D.2
Tillman, T.3
Cui, T.4
Liu, L.T.5
Xu, Y.6
Tang, P.7
-
5
-
-
84894622604
-
NMR structures of the human alpha7 nAChR transmembrane domain and associated anesthetic binding sites
-
V. Bondarenko, D.D. Mowrey, T.S. Tillman, E. Seyoum, Y. Xu, and P. Tang NMR structures of the human alpha7 nAChR transmembrane domain and associated anesthetic binding sites Biochim. Biophys. Acta 1838 2014 1389 1395
-
(2014)
Biochim. Biophys. Acta
, vol.1838
, pp. 1389-1395
-
-
Bondarenko, V.1
Mowrey, D.D.2
Tillman, T.S.3
Seyoum, E.4
Xu, Y.5
Tang, P.6
-
6
-
-
33646189366
-
Utilizing ESEEM spectroscopy to locate the position of specific regions of membrane-active peptides within model membranes
-
R. Carmieli, N. Papo, H. Zimmermann, A. Potapov, Y. Shai, and D. Goldfarb Utilizing ESEEM spectroscopy to locate the position of specific regions of membrane-active peptides within model membranes Biophys. J. 90 2006 492 505
-
(2006)
Biophys. J.
, vol.90
, pp. 492-505
-
-
Carmieli, R.1
Papo, N.2
Zimmermann, H.3
Potapov, A.4
Shai, Y.5
Goldfarb, D.6
-
7
-
-
41649119572
-
Pore-opening mechanism of the nicotinic acetylcholine receptor evinced by proton transfer
-
G.D. Cymes, and C. Grosman Pore-opening mechanism of the nicotinic acetylcholine receptor evinced by proton transfer Nat. Struct. Mol. Biol. 15 2008 389 396
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 389-396
-
-
Cymes, G.D.1
Grosman, C.2
-
8
-
-
84870378961
-
The unanticipated complexity of the selectivity-filter glutamates of nicotinic receptors
-
G.D. Cymes, and C. Grosman The unanticipated complexity of the selectivity-filter glutamates of nicotinic receptors Nat. Chem. Biol. 8 2012 975 981
-
(2012)
Nat. Chem. Biol.
, vol.8
, pp. 975-981
-
-
Cymes, G.D.1
Grosman, C.2
-
9
-
-
84867053372
-
Symmetry-constrained analysis of pulsed double electron-electron resonance (DEER) spectroscopy reveals the dynamic nature of the KcsA activation gate
-
O. Dalmas, H.C. Hyde, R.E. Hulse, and E. Perozo Symmetry-constrained analysis of pulsed double electron-electron resonance (DEER) spectroscopy reveals the dynamic nature of the KcsA activation gate J. Am. Chem. Soc. 134 2012 16360 16369
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 16360-16369
-
-
Dalmas, O.1
Hyde, H.C.2
Hulse, R.E.3
Perozo, E.4
-
10
-
-
0029665619
-
Use of F-19 NMR to probe protein structure and conformational changes
-
M.A. Danielson, and J.J. Falke Use of F-19 NMR to probe protein structure and conformational changes Annu. Rev. Biophys. Biomol. Struct. 25 1996 163 195
-
(1996)
Annu. Rev. Biophys. Biomol. Struct.
, vol.25
, pp. 163-195
-
-
Danielson, M.A.1
Falke, J.J.2
-
11
-
-
33846823909
-
Particle Mesh Ewald - an N.log(N) method for Ewald sums in large systems
-
T. Darden, D. York, and L. Pedersen Particle Mesh Ewald - an N.log(N) method for Ewald sums in large systems J. Chem. Phys. 98 1993 10089 10092
-
(1993)
J. Chem. Phys.
, vol.98
, pp. 10089-10092
-
-
Darden, T.1
York, D.2
Pedersen, L.3
-
12
-
-
84889038866
-
Site-directed spin labeling reveals pentameric ligand-gated ion channel gating motions
-
C.D. Dellisanti, B. Ghosh, S.M. Hanson, J.M. Raspanti, V.A. Grant, G.M. Diarra, A.M. Schuh, K. Satyshur, C.S. Klug, and C. Czajkowski Site-directed spin labeling reveals pentameric ligand-gated ion channel gating motions PLoS Biol. 11 2013 e1001714
-
(2013)
PLoS Biol.
, vol.11
-
-
Dellisanti, C.D.1
Ghosh, B.2
Hanson, S.M.3
Raspanti, J.M.4
Grant, V.A.5
Diarra, G.M.6
Schuh, A.M.7
Satyshur, K.8
Klug, C.S.9
Czajkowski, C.10
-
13
-
-
0030656992
-
Single binding versus single channel recordings: a new approach to study ionotropic receptors
-
S.J. Edelstein, O. Schaad, and J.P. Changeux Single binding versus single channel recordings: a new approach to study ionotropic receptors Biochemistry 36 1997 13755 13760
-
(1997)
Biochemistry
, vol.36
, pp. 13755-13760
-
-
Edelstein, S.J.1
Schaad, O.2
Changeux, J.P.3
-
14
-
-
84859963646
-
Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals
-
G. Gonzalez-Gutierrez, T. Lukk, V. Agarwal, D. Papke, S.K. Nair, and C. Grosman Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals Proc. Natl. Acad. Sci. USA 109 2012 6331 6336
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 6331-6336
-
-
Gonzalez-Gutierrez, G.1
Lukk, T.2
Agarwal, V.3
Papke, D.4
Nair, S.K.5
Grosman, C.6
-
15
-
-
84906545550
-
X-Ray structure of the mouse serotonin 5-HT3 receptor
-
G. Hassaine, C. Deluz, L. Grasso, R. Wyss, M.B. Tol, R. Hovius, A. Graff, H. Stahlberg, T. Tomizaki, and A. Desmyter X-Ray structure of the mouse serotonin 5-HT3 receptor Nature 512 2014 276 281
-
(2014)
Nature
, vol.512
, pp. 276-281
-
-
Hassaine, G.1
Deluz, C.2
Grasso, L.3
Wyss, R.4
Tol, M.B.5
Hovius, R.6
Graff, A.7
Stahlberg, H.8
Tomizaki, T.9
Desmyter, A.10
-
16
-
-
48549102871
-
United-atom acyl chains for CHARMM phospholipids
-
J. Henin, W. Shinoda, and M.L. Klein United-atom acyl chains for CHARMM phospholipids J. Phys. Chem. B 112 2008 7008 7015
-
(2008)
J. Phys. Chem. B
, vol.112
, pp. 7008-7015
-
-
Henin, J.1
Shinoda, W.2
Klein, M.L.3
-
17
-
-
79957953215
-
Principles of activation and permeation in an anion-selective Cys-loop receptor
-
R.E. Hibbs, and E. Gouaux Principles of activation and permeation in an anion-selective Cys-loop receptor Nature 474 2011 54 60
-
(2011)
Nature
, vol.474
, pp. 54-60
-
-
Hibbs, R.E.1
Gouaux, E.2
-
18
-
-
41149168686
-
X-Ray structure of a prokaryotic pentameric ligand-gated ion channel
-
R.J. Hilf, and R. Dutzler X-Ray structure of a prokaryotic pentameric ligand-gated ion channel Nature 452 2008 375 379
-
(2008)
Nature
, vol.452
, pp. 375-379
-
-
Hilf, R.J.1
Dutzler, R.2
-
19
-
-
58149242730
-
Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel
-
R.J. Hilf, and R. Dutzler Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel Nature 457 2009 115 118
-
(2009)
Nature
, vol.457
, pp. 115-118
-
-
Hilf, R.J.1
Dutzler, R.2
-
21
-
-
84859888767
-
DEER distance measurements on proteins
-
G. Jeschke DEER distance measurements on proteins Annu. Rev. Phys. Chem. 63 2012 419 446
-
(2012)
Annu. Rev. Phys. Chem.
, vol.63
, pp. 419-446
-
-
Jeschke, G.1
-
22
-
-
1942487282
-
Interresidual distance determination by four-pulse double electron-electron resonance in an integral membrane protein: the Na+/proline transporter PutP of Escherichia coli
-
G. Jeschke, C. Wegener, M. Nietschke, H. Jung, and H.J. Steinhoff Interresidual distance determination by four-pulse double electron-electron resonance in an integral membrane protein: the Na+/proline transporter PutP of Escherichia coli Biophys. J. 86 2004 2551 2557
-
(2004)
Biophys. J.
, vol.86
, pp. 2551-2557
-
-
Jeschke, G.1
Wegener, C.2
Nietschke, M.3
Jung, H.4
Steinhoff, H.J.5
-
23
-
-
33846344623
-
DeerAnalysis2006 - a comprehensive software package for analyzing pulsed ELDOR data
-
G. Jeschke, V. Chechik, P. Ionita, A. Godt, H. Zimmermann, J. Banham, C.R. Timmel, D. Hilger, and H. Jung DeerAnalysis2006 - a comprehensive software package for analyzing pulsed ELDOR data Appl. Magn. Reson. 30 2006 473 498
-
(2006)
Appl. Magn. Reson.
, vol.30
, pp. 473-498
-
-
Jeschke, G.1
Chechik, V.2
Ionita, P.3
Godt, A.4
Zimmermann, H.5
Banham, J.6
Timmel, C.R.7
Hilger, D.8
Jung, H.9
-
24
-
-
84876681700
-
An outline of desensitization in pentameric ligand-gated ion channel receptors
-
A. Keramidas, and J.W. Lynch An outline of desensitization in pentameric ligand-gated ion channel receptors Cell. Mol. Life Sci. 70 2013 1241 1253
-
(2013)
Cell. Mol. Life Sci.
, vol.70
, pp. 1241-1253
-
-
Keramidas, A.1
Lynch, J.W.2
-
26
-
-
0033598692
-
NMR spectroscopy in studies of light-induced structural changes in mammalian rhodopsin: applicability of solution (19)F NMR
-
J. Klein-Seetharaman, E.V. Getmanova, M.C. Loewen, P.J. Reeves, and H.G. Khorana NMR spectroscopy in studies of light-induced structural changes in mammalian rhodopsin: applicability of solution (19)F NMR Proc. Natl. Acad. Sci. USA 96 1999 13744 13749
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 13744-13749
-
-
Klein-Seetharaman, J.1
Getmanova, E.V.2
Loewen, M.C.3
Reeves, P.J.4
Khorana, H.G.5
-
27
-
-
84862776738
-
Biased signaling pathways in beta2-adrenergic receptor characterized by 19F-NMR
-
J.J. Liu, R. Horst, V. Katritch, R.C. Stevens, and K. Wuthrich Biased signaling pathways in beta2-adrenergic receptor characterized by 19F-NMR Science 335 2012 1106 1110
-
(2012)
Science
, vol.335
, pp. 1106-1110
-
-
Liu, J.J.1
Horst, R.2
Katritch, V.3
Stevens, R.C.4
Wuthrich, K.5
-
28
-
-
0028427909
-
Fluorinated proteins as potential 19F magnetic resonance imaging and spectroscopy agents
-
V.D. Mehta, P.V. Kulkarni, R.P. Mason, A. Constantinescu, and P.P. Antich Fluorinated proteins as potential 19F magnetic resonance imaging and spectroscopy agents Bioconjug. Chem. 5 1994 257 261
-
(1994)
Bioconjug. Chem.
, vol.5
, pp. 257-261
-
-
Mehta, V.D.1
Kulkarni, P.V.2
Mason, R.P.3
Constantinescu, A.4
Antich, P.P.5
-
29
-
-
0024623211
-
Genetic manipulation of ion channels: a new approach to structure and mechanism
-
C. Miller Genetic manipulation of ion channels: a new approach to structure and mechanism Neuron 2 1989 1195 1205
-
(1989)
Neuron
, vol.2
, pp. 1195-1205
-
-
Miller, C.1
-
30
-
-
84905669878
-
Crystal structure of a human GABA receptor
-
P.S. Miller, and A.R. Aricescu Crystal structure of a human GABA receptor Nature 512 2014 270 275
-
(2014)
Nature
, vol.512
, pp. 270-275
-
-
Miller, P.S.1
Aricescu, A.R.2
-
31
-
-
0034728579
-
The static magnetic field dependence of chemical exchange linebroadening defines the NMR chemical shift time scale
-
O. Millet, J.P. Loria, C.D. Kroenke, M. Pons, and A.G. Palmer The static magnetic field dependence of chemical exchange linebroadening defines the NMR chemical shift time scale J. Am. Chem. Soc. 122 2000 2867 2877
-
(2000)
J. Am. Chem. Soc.
, vol.122
, pp. 2867-2877
-
-
Millet, O.1
Loria, J.P.2
Kroenke, C.D.3
Pons, M.4
Palmer, A.G.5
-
32
-
-
35949043972
-
Envelope modulation in spin-echo experiments
-
W.B. Mims Envelope modulation in spin-echo experiments Phys. Rev. B 5 1972 2409
-
(1972)
Phys. Rev. B
, vol.5
, pp. 2409
-
-
Mims, W.B.1
-
33
-
-
0033013979
-
The startle disease mutation Q266H, in the second transmembrane domain of the human glycine receptor, impairs channel gating
-
A.J. Moorhouse, P. Jacques, P.H. Barry, and P.R. Schofield The startle disease mutation Q266H, in the second transmembrane domain of the human glycine receptor, impairs channel gating Mol. Pharmacol. 55 1999 386 395
-
(1999)
Mol. Pharmacol.
, vol.55
, pp. 386-395
-
-
Moorhouse, A.J.1
Jacques, P.2
Barry, P.H.3
Schofield, P.R.4
-
34
-
-
84873620326
-
Asymmetric ligand binding facilitates conformational transitions in pentameric ligand-gated ion channels
-
D. Mowrey, M.H. Cheng, L.T. Liu, D. Willenbring, X. Lu, T. Wymore, Y. Xu, and P. Tang Asymmetric ligand binding facilitates conformational transitions in pentameric ligand-gated ion channels J. Am. Chem. Soc. 135 2013 2172 2180
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 2172-2180
-
-
Mowrey, D.1
Cheng, M.H.2
Liu, L.T.3
Willenbring, D.4
Lu, X.5
Wymore, T.6
Xu, Y.7
Tang, P.8
-
35
-
-
84885435090
-
Open-channel structures of the human glycine receptor alpha1 full-length transmembrane domain
-
D.D. Mowrey, T. Cui, Y. Jia, D. Ma, A.M. Makhov, P. Zhang, P. Tang, and Y. Xu Open-channel structures of the human glycine receptor alpha1 full-length transmembrane domain Structure 21 2013 1897 1904
-
(2013)
Structure
, vol.21
, pp. 1897-1904
-
-
Mowrey, D.D.1
Cui, T.2
Jia, Y.3
Ma, D.4
Makhov, A.M.5
Zhang, P.6
Tang, P.7
Xu, Y.8
-
36
-
-
84890322680
-
Insights into distinct modulation of alpha7 and alpha7beta2 nicotinic acetylcholine receptors by the volatile anesthetic isoflurane
-
D.D. Mowrey, Q. Liu, V. Bondarenko, Q. Chen, E. Seyoum, Y. Xu, J. Wu, and P. Tang Insights into distinct modulation of alpha7 and alpha7beta2 nicotinic acetylcholine receptors by the volatile anesthetic isoflurane J. Biol. Chem. 288 2013 35793 35800
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 35793-35800
-
-
Mowrey, D.D.1
Liu, Q.2
Bondarenko, V.3
Chen, Q.4
Seyoum, E.5
Xu, Y.6
Wu, J.7
Tang, P.8
-
37
-
-
84979859115
-
Atomistic insights into human Cys-loop receptors by solution NMR
-
D.D. Mowrey, M.N. Kinde, Y. Xu, and P. Tang Atomistic insights into human Cys-loop receptors by solution NMR Biochim. Biophys. Acta 1848 2014 307 314
-
(2014)
Biochim. Biophys. Acta
, vol.1848
, pp. 307-314
-
-
Mowrey, D.D.1
Kinde, M.N.2
Xu, Y.3
Tang, P.4
-
38
-
-
84865731022
-
Structure of the pentameric ligand-gated ion channel GLIC bound with anesthetic ketamine
-
J. Pan, Q. Chen, D. Willenbring, D. Mowrey, X.P. Kong, A. Cohen, C.B. Divito, Y. Xu, and P. Tang Structure of the pentameric ligand-gated ion channel GLIC bound with anesthetic ketamine Structure 20 2012 1463 1469
-
(2012)
Structure
, vol.20
, pp. 1463-1469
-
-
Pan, J.1
Chen, Q.2
Willenbring, D.3
Mowrey, D.4
Kong, X.P.5
Cohen, A.6
Divito, C.B.7
Xu, Y.8
Tang, P.9
-
39
-
-
84859173541
-
Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine
-
J. Pan, Q. Chen, D. Willenbring, K. Yoshida, T. Tillman, O.B. Kashlan, A. Cohen, X.P. Kong, Y. Xu, and P. Tang Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine Nat. Commun. 3 2012 714
-
(2012)
Nat. Commun.
, vol.3
, pp. 714
-
-
Pan, J.1
Chen, Q.2
Willenbring, D.3
Yoshida, K.4
Tillman, T.5
Kashlan, O.B.6
Cohen, A.7
Kong, X.P.8
Xu, Y.9
Tang, P.10
-
40
-
-
0034132251
-
Dead-time free measurement of dipole-dipole interactions between electron spins
-
M. Pannier, S. Veit, A. Godt, G. Jeschke, and H.W. Spiess Dead-time free measurement of dipole-dipole interactions between electron spins J. Magn. Reson. 142 2000 331 340
-
(2000)
J. Magn. Reson.
, vol.142
, pp. 331-340
-
-
Pannier, M.1
Veit, S.2
Godt, A.3
Jeschke, G.4
Spiess, H.W.5
-
41
-
-
79954568593
-
Structure of the M2 transmembrane segment of GLIC, a prokaryotic Cys loop receptor homologue from Gloeobacter violaceus, probed by substituted cysteine accessibility
-
R.B. Parikh, M. Bali, and M.H. Akabas Structure of the M2 transmembrane segment of GLIC, a prokaryotic Cys loop receptor homologue from Gloeobacter violaceus, probed by substituted cysteine accessibility J. Biol. Chem. 286 2011 14098 14109
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 14098-14109
-
-
Parikh, R.B.1
Bali, M.2
Akabas, M.H.3
-
42
-
-
80052033738
-
Research update: Alpha7 nicotinic acetylcholine receptor mechanisms in Alzheimer's disease
-
H.R. Parri, C.M. Hernandez, and K.T. Dineley Research update: Alpha7 nicotinic acetylcholine receptor mechanisms in Alzheimer's disease Biochem. Pharmacol. 82 2011 931 942
-
(2011)
Biochem. Pharmacol.
, vol.82
, pp. 931-942
-
-
Parri, H.R.1
Hernandez, C.M.2
Dineley, K.T.3
-
43
-
-
27344436659
-
Scalable molecular dynamics with NAMD
-
J.C. Phillips, R. Braun, W. Wang, J. Gumbart, E. Tajkhorshid, E. Villa, C. Chipot, R.D. Skeel, L. Kale, and K. Schulten Scalable molecular dynamics with NAMD J. Comput. Chem. 26 2005 1781 1802
-
(2005)
J. Comput. Chem.
, vol.26
, pp. 1781-1802
-
-
Phillips, J.C.1
Braun, R.2
Wang, W.3
Gumbart, J.4
Tajkhorshid, E.5
Villa, E.6
Chipot, C.7
Skeel, R.D.8
Kale, L.9
Schulten, K.10
-
45
-
-
33746807794
-
Location and aggregation of the spin-labeled peptide trichogin GA IV in a phospholipid membrane as revealed by pulsed EPR
-
E.S. Salnikov, D.A. Erilov, A.D. Milov, Y.D. Tsvetkov, C. Peggion, F. Formaggio, C. Toniolo, J. Raap, and S.A. Dzuba Location and aggregation of the spin-labeled peptide trichogin GA IV in a phospholipid membrane as revealed by pulsed EPR Biophys. J. 91 2006 1532 1540
-
(2006)
Biophys. J.
, vol.91
, pp. 1532-1540
-
-
Salnikov, E.S.1
Erilov, D.A.2
Milov, A.D.3
Tsvetkov, Y.D.4
Peggion, C.5
Formaggio, F.6
Toniolo, C.7
Raap, J.8
Dzuba, S.A.9
-
46
-
-
84892910277
-
Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation
-
L. Sauguet, A. Shahsavar, F. Poitevin, C. Huon, A. Menny, A. Nemecz, A. Haouz, J.P. Changeux, P.J. Corringer, and M. Delarue Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation Proc. Natl. Acad. Sci. USA 111 2014 966 971
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 966-971
-
-
Sauguet, L.1
Shahsavar, A.2
Poitevin, F.3
Huon, C.4
Menny, A.5
Nemecz, A.6
Haouz, A.7
Changeux, J.P.8
Corringer, P.J.9
Delarue, M.10
-
47
-
-
84905393641
-
ESEEM analysis of multi-histidine Cu(II)-coordination in model complexes, peptides, and amyloid-beta
-
K.I. Silva, B.C. Michael, S.J. Geib, and S. Saxena ESEEM analysis of multi-histidine Cu(II)-coordination in model complexes, peptides, and amyloid-beta J. Phys. Chem. B 118 2014 8935 8944
-
(2014)
J. Phys. Chem. B
, vol.118
, pp. 8935-8944
-
-
Silva, K.I.1
Michael, B.C.2
Geib, S.J.3
Saxena, S.4
-
48
-
-
84868116573
-
Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines
-
R. Spurny, J. Ramerstorfer, K. Price, M. Brams, M. Ernst, H. Nury, M. Verheij, P. Legrand, D. Bertrand, and S. Bertrand Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines Proc. Natl. Acad. Sci. USA 109 2012 E3028 E3034
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. E3028-E3034
-
-
Spurny, R.1
Ramerstorfer, J.2
Price, K.3
Brams, M.4
Ernst, M.5
Nury, H.6
Verheij, M.7
Legrand, P.8
Bertrand, D.9
Bertrand, S.10
-
49
-
-
84906509939
-
Origins of structural flexibility in protein-based supramolecular polymers revealed by DEER spectroscopy
-
N.A. Tavenor, K.I. Silva, S. Saxena, and W.S. Horne Origins of structural flexibility in protein-based supramolecular polymers revealed by DEER spectroscopy J. Phys. Chem. B 118 2014 9881 9889
-
(2014)
J. Phys. Chem. B
, vol.118
, pp. 9881-9889
-
-
Tavenor, N.A.1
Silva, K.I.2
Saxena, S.3
Horne, W.S.4
-
50
-
-
84870935940
-
Reversal of ion-charge selectivity renders the pentameric ligand-gated ion channel GLIC insensitive to anaesthetics
-
T. Tillman, M.H. Cheng, Q. Chen, P. Tang, and Y. Xu Reversal of ion-charge selectivity renders the pentameric ligand-gated ion channel GLIC insensitive to anaesthetics Biochem. J. 449 2013 61 68
-
(2013)
Biochem. J.
, vol.449
, pp. 61-68
-
-
Tillman, T.1
Cheng, M.H.2
Chen, Q.3
Tang, P.4
Xu, Y.5
-
51
-
-
84901044877
-
ELIC-alpha7 nicotinic acetylcholine receptor (alpha7nAChR) chimeras reveal a prominent role of the extracellular-transmembrane domain interface in allosteric modulation
-
T.S. Tillman, E. Seyoum, D.D. Mowrey, Y. Xu, and P. Tang ELIC-alpha7 nicotinic acetylcholine receptor (alpha7nAChR) chimeras reveal a prominent role of the extracellular-transmembrane domain interface in allosteric modulation J. Biol. Chem. 289 2014 13851 13857
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 13851-13857
-
-
Tillman, T.S.1
Seyoum, E.2
Mowrey, D.D.3
Xu, Y.4
Tang, P.5
-
52
-
-
13444271681
-
Refined structure of the nicotinic acetylcholine receptor at 4A resolution
-
N. Unwin Refined structure of the nicotinic acetylcholine receptor at 4A resolution J. Mol. Biol. 346 2005 967 989
-
(2005)
J. Mol. Biol.
, vol.346
, pp. 967-989
-
-
Unwin, N.1
-
53
-
-
84865696393
-
Gating movement of acetylcholine receptor caught by plunge-freezing
-
N. Unwin, and Y. Fujiyoshi Gating movement of acetylcholine receptor caught by plunge-freezing J. Mol. Biol. 422 2012 617 634
-
(2012)
J. Mol. Biol.
, vol.422
, pp. 617-634
-
-
Unwin, N.1
Fujiyoshi, Y.2
-
54
-
-
84861537525
-
Desensitization mechanism in prokaryotic ligand-gated ion channel
-
P. Velisetty, and S. Chakrapani Desensitization mechanism in prokaryotic ligand-gated ion channel J. Biol. Chem. 287 2012 18467 18477
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 18467-18477
-
-
Velisetty, P.1
Chakrapani, S.2
-
55
-
-
84868258417
-
Conformational transitions underlying pore opening and desensitization in membrane-embedded Gloeobacter violaceus ligand-gated ion channel (GLIC)
-
P. Velisetty, S.V. Chalamalasetti, and S. Chakrapani Conformational transitions underlying pore opening and desensitization in membrane-embedded Gloeobacter violaceus ligand-gated ion channel (GLIC) J. Biol. Chem. 287 2012 36864 36872
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 36864-36872
-
-
Velisetty, P.1
Chalamalasetti, S.V.2
Chakrapani, S.3
-
56
-
-
84893466183
-
Structural basis for allosteric coupling at the membrane-protein interface in Gloeobacter violaceus ligand-gated ion channel (GLIC)
-
P. Velisetty, S.V. Chalamalasetti, and S. Chakrapani Structural basis for allosteric coupling at the membrane-protein interface in Gloeobacter violaceus ligand-gated ion channel (GLIC) J. Biol. Chem. 289 2014 3013 3025
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 3013-3025
-
-
Velisetty, P.1
Chalamalasetti, S.V.2
Chakrapani, S.3
-
57
-
-
80055074583
-
Activation and desensitization induce distinct conformational changes at the extracellular-transmembrane domain interface of the glycine receptor
-
Q. Wang, and J.W. Lynch Activation and desensitization induce distinct conformational changes at the extracellular-transmembrane domain interface of the glycine receptor J. Biol. Chem. 286 2011 38814 38824
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 38814-38824
-
-
Wang, Q.1
Lynch, J.W.2
-
58
-
-
0035970016
-
Acetylcholine receptor channel structure in the resting, open, and desensitized states probed with the substituted-cysteine-accessibility method
-
G. Wilson, and A. Karlin Acetylcholine receptor channel structure in the resting, open, and desensitized states probed with the substituted-cysteine-accessibility method Proc. Natl. Acad. Sci. USA 98 2001 1241 1248
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 1241-1248
-
-
Wilson, G.1
Karlin, A.2
-
59
-
-
79960120380
-
Desensitization of alpha7 nicotinic receptor is governed by coupling strength relative to gate tightness
-
J. Zhang, F. Xue, P. Whiteaker, C. Li, W. Wu, B. Shen, Y. Huang, R.J. Lukas, and Y. Chang Desensitization of alpha7 nicotinic receptor is governed by coupling strength relative to gate tightness J. Biol. Chem. 286 2011 25331 25340
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 25331-25340
-
-
Zhang, J.1
Xue, F.2
Whiteaker, P.3
Li, C.4
Wu, W.5
Shen, B.6
Huang, Y.7
Lukas, R.J.8
Chang, Y.9
-
60
-
-
79959775185
-
Ligand activation of the prokaryotic pentameric ligand-gated ion channel ELIC
-
I. Zimmermann, and R. Dutzler Ligand activation of the prokaryotic pentameric ligand-gated ion channel ELIC PLoS Biol. 9 2011 e1001101
-
(2011)
PLoS Biol.
, vol.9
-
-
Zimmermann, I.1
Dutzler, R.2
|