X-ray structure of the human α4β2 nicotinic receptor

Nature

Volumn 538, Issue 7625, 2016, Pages 411-415

  Morales Perez, Claudio L ^a   Noviello, Colleen M ^a   Hibbs, Ryan E ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; CYSTEINE LOOP LIGAND GATED ION CHANNEL RECEPTOR; NICOTINE; NICOTINIC RECEPTOR ALPHA4BETA2; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; EPIBATIDINE; FUSED HETEROCYCLIC RINGS; LIGAND; NICOTINIC AGENT; NICOTINIC RECEPTOR; PYRIDINE DERIVATIVE;

CELLS AND CELL COMPONENTS; CHEMICAL BINDING; EUKARYOTE; LIGAND; NERVOUS SYSTEM; NUMERICAL MODEL; PHYSIOLOGY; X-RAY;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CRYSTALLIZATION; DISULFIDE BOND; HUMAN; HYDROGEN BOND; ION TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT; STOICHIOMETRY; X RAY CRYSTALLOGRAPHY; BINDING SITE; CHEMISTRY; METABOLISM; MOLECULAR MODEL; PROTEIN QUATERNARY STRUCTURE;

EUKARYOTA; TORPEDO MARMORATA;

BINDING SITES; BRIDGED BICYCLO COMPOUNDS, HETEROCYCLIC; CRYSTALLOGRAPHY, X-RAY; HUMANS; ION TRANSPORT; LIGANDS; MODELS, MOLECULAR; NEUROTRANSMITTER AGENTS; NICOTINIC AGONISTS; PROTEIN STRUCTURE, QUATERNARY; PYRIDINES; RECEPTORS, NICOTINIC;

EID: 84992407828     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature19785     Document Type: Article

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