-
1
-
-
0031863853
-
Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes
-
Zitvogel, L., et al. Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes. Nat. Med. 4 (1998), 594–600.
-
(1998)
Nat. Med.
, vol.4
, pp. 594-600
-
-
Zitvogel, L.1
-
2
-
-
20244373139
-
Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming
-
Wolfers, J., et al. Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. Nat. Med. 7 (2001), 297–303.
-
(2001)
Nat. Med.
, vol.7
, pp. 297-303
-
-
Wolfers, J.1
-
3
-
-
84964853782
-
Exosome-mediated metastasis: from epithelial – mesenchymal transition to escape from immunosurveillance
-
Syn, N., et al. Exosome-mediated metastasis: from epithelial – mesenchymal transition to escape from immunosurveillance. Trends Pharmacol. Sci. 37 (2016), 606–616.
-
(2016)
Trends Pharmacol. Sci.
, vol.37
, pp. 606-616
-
-
Syn, N.1
-
4
-
-
84947723880
-
Tumour exosome integrins determine organotropic metastasis
-
Hoshino, A., et al. Tumour exosome integrins determine organotropic metastasis. Nature 527 (2015), 329–335.
-
(2015)
Nature
, vol.527
, pp. 329-335
-
-
Hoshino, A.1
-
5
-
-
84944201151
-
Exosomal doxorubicin reduces the cardiac toxicity of doxorubicin
-
Toffoli, G., et al. Exosomal doxorubicin reduces the cardiac toxicity of doxorubicin. Nanomedicine 10 (2015), 2963–2971.
-
(2015)
Nanomedicine
, vol.10
, pp. 2963-2971
-
-
Toffoli, G.1
-
6
-
-
84984714282
-
Exosomes increase the therapeutic index of doxorubicin in breast and ovarian cancer mouse models
-
Hadla, M., et al. Exosomes increase the therapeutic index of doxorubicin in breast and ovarian cancer mouse models. Nanomedicine 11 (2016), 2431–2441.
-
(2016)
Nanomedicine
, vol.11
, pp. 2431-2441
-
-
Hadla, M.1
-
7
-
-
84891372823
-
A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy
-
Tian, Y., et al. A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy. Biomaterials 35 (2014), 2383–2390.
-
(2014)
Biomaterials
, vol.35
, pp. 2383-2390
-
-
Tian, Y.1
-
8
-
-
85006043524
-
Nanosomes carrying doxorubicin exhibit potent anticancer activity against human lung cancer cells
-
Srivastava, A., et al. Nanosomes carrying doxorubicin exhibit potent anticancer activity against human lung cancer cells. Sci. Rep., 6, 2016, 38541.
-
(2016)
Sci. Rep.
, vol.6
, pp. 38541
-
-
Srivastava, A.1
-
9
-
-
84973293346
-
Exosomal formulation enhances therapeutic response of celastrol against lung cancer
-
Aqil, F., et al. Exosomal formulation enhances therapeutic response of celastrol against lung cancer. Exp. Mol. Pathol. 101 (2016), 12–21.
-
(2016)
Exp. Mol. Pathol.
, vol.101
, pp. 12-21
-
-
Aqil, F.1
-
10
-
-
84959440540
-
Development of exosome-encapsulated paclitaxel to overcome MDR in cancer cells
-
Kim, M.S., et al. Development of exosome-encapsulated paclitaxel to overcome MDR in cancer cells. Nanomedicine Nanotechnology, Biol. Med. 12 (2016), 655–664.
-
(2016)
Nanomedicine Nanotechnology, Biol. Med.
, vol.12
, pp. 655-664
-
-
Kim, M.S.1
-
11
-
-
84949564767
-
Microvesicle- and exosome-mediated drug delivery enhances the cytotoxicity of Paclitaxel in autologous prostate cancer cells
-
Saari, H., et al. Microvesicle- and exosome-mediated drug delivery enhances the cytotoxicity of Paclitaxel in autologous prostate cancer cells. J. Control. Release 220 (2015), 727–737.
-
(2015)
J. Control. Release
, vol.220
, pp. 727-737
-
-
Saari, H.1
-
12
-
-
84907228576
-
Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: a new approach for drug delivery
-
Pascucci, L., et al. Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: a new approach for drug delivery. J. Control. Release 192 (2014), 262–270.
-
(2014)
J. Control. Release
, vol.192
, pp. 262-270
-
-
Pascucci, L.1
-
13
-
-
84935026792
-
Exosome delivered anticancer drugs across the blood-brain barrier for brain cancer therapy in Danio rerio
-
Yang, T., et al. Exosome delivered anticancer drugs across the blood-brain barrier for brain cancer therapy in Danio rerio. Pharm. Res. 32 (2015), 2003–2014.
-
(2015)
Pharm. Res.
, vol.32
, pp. 2003-2014
-
-
Yang, T.1
-
14
-
-
85015307223
-
Presence of Cx43 in extracellular vesicles reduces the cardiotoxicity of the anti-tumour therapeutic approach with doxorubicin
-
Martins-Marques, T., Presence of Cx43 in extracellular vesicles reduces the cardiotoxicity of the anti-tumour therapeutic approach with doxorubicin. J. Extracell. Vesicles, 5, 2016, 32538.
-
(2016)
J. Extracell. Vesicles
, vol.5
, pp. 32538
-
-
Martins-Marques, T.1
-
15
-
-
84939125357
-
Increased anti-tumour activity by exosomes derived from doxorubicin-treated tumour cells via heat stress
-
Yang, Y., et al. Increased anti-tumour activity by exosomes derived from doxorubicin-treated tumour cells via heat stress. Int. J. Hyperth. 31 (2015), 498–506.
-
(2015)
Int. J. Hyperth.
, vol.31
, pp. 498-506
-
-
Yang, Y.1
-
16
-
-
85013654823
-
Routes and mechanisms of extracellular vesicle uptake
-
Mulcahy, L.A., et al. Routes and mechanisms of extracellular vesicle uptake. J. Extracell. Vesicles, 3, 2014, 24641.
-
(2014)
J. Extracell. Vesicles
, vol.3
, pp. 24641
-
-
Mulcahy, L.A.1
-
17
-
-
84875520481
-
Dynamics of exosome internalization and trafficking
-
Tian, T., et al. Dynamics of exosome internalization and trafficking. J. Cell. Physiol. 228 (2013), 1487–1495.
-
(2013)
J. Cell. Physiol.
, vol.228
, pp. 1487-1495
-
-
Tian, T.1
-
18
-
-
84969262605
-
Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER
-
Heusermann, W., et al. Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER. J. Cell Biol. 213 (2016), 173–184.
-
(2016)
J. Cell Biol.
, vol.213
, pp. 173-184
-
-
Heusermann, W.1
-
19
-
-
84978492523
-
TNF-related apoptosis-inducing ligand (TRAIL)-armed exosomes deliver proapoptotic signals to tumor site
-
Rivoltini, L., et al. TNF-related apoptosis-inducing ligand (TRAIL)-armed exosomes deliver proapoptotic signals to tumor site. Clin. Cancer Res. 22 (2016), 3499–3512.
-
(2016)
Clin. Cancer Res.
, vol.22
, pp. 3499-3512
-
-
Rivoltini, L.1
-
20
-
-
84896071176
-
Exosome-formed synthetic microRNA-143 is transferred to osteosarcoma cells and inhibits their migration
-
Shimbo, K., et al. Exosome-formed synthetic microRNA-143 is transferred to osteosarcoma cells and inhibits their migration. Biochem. Biophys. Res. Commun. 445 (2014), 381–387.
-
(2014)
Biochem. Biophys. Res. Commun.
, vol.445
, pp. 381-387
-
-
Shimbo, K.1
-
21
-
-
84871923602
-
Systemically injected exosomes targeted to EGFR deliver antitumor microRNA to breast cancer cells
-
Ohno, S., et al. Systemically injected exosomes targeted to EGFR deliver antitumor microRNA to breast cancer cells. Mol. Ther. 21 (2013), 185–191.
-
(2013)
Mol. Ther.
, vol.21
, pp. 185-191
-
-
Ohno, S.1
-
22
-
-
85010274145
-
Extracellular vesicles carry microRNA-195 to intrahepatic cholangiocarcinoma and improve survival in a rat model
-
Li, L., et al. Extracellular vesicles carry microRNA-195 to intrahepatic cholangiocarcinoma and improve survival in a rat model. Hepatology 24 (2016), 38–44.
-
(2016)
Hepatology
, vol.24
, pp. 38-44
-
-
Li, L.1
-
23
-
-
85006295096
-
Extracellular vesicle-mediated suicide mRNA/protein delivery inhibits glioblastoma tumor growth in vivo
-
Erkan, E.P., et al. Extracellular vesicle-mediated suicide mRNA/protein delivery inhibits glioblastoma tumor growth in vivo. Cancer Gene Ther. 24 (2016), 38–44.
-
(2016)
Cancer Gene Ther.
, vol.24
, pp. 38-44
-
-
Erkan, E.P.1
-
24
-
-
84871923988
-
Genetically engineered microvesicles carrying suicide mRNA/protein inhibit schwannoma tumor growth
-
Mizrak, A., et al. Genetically engineered microvesicles carrying suicide mRNA/protein inhibit schwannoma tumor growth. Mol. Ther. 21 (2013), 101–108.
-
(2013)
Mol. Ther.
, vol.21
, pp. 101-108
-
-
Mizrak, A.1
-
25
-
-
84991728459
-
In vitro and ex vivo strategies for intracellular delivery
-
Stewart, M.P., et al. In vitro and ex vivo strategies for intracellular delivery. Nature 538 (2016), 183–192.
-
(2016)
Nature
, vol.538
, pp. 183-192
-
-
Stewart, M.P.1
-
26
-
-
84911966357
-
Cancer exosomes perform cell-independent MicroRNA biogenesis and promote tumorigenesis
-
Melo, S.A., et al. Cancer exosomes perform cell-independent MicroRNA biogenesis and promote tumorigenesis. Cancer Cell 26 (2014), 707–721.
-
(2014)
Cancer Cell
, vol.26
, pp. 707-721
-
-
Melo, S.A.1
-
27
-
-
84898476721
-
Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis
-
Zhou, W., et al. Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis. Cancer Cell 25 (2014), 501–515.
-
(2014)
Cancer Cell
, vol.25
, pp. 501-515
-
-
Zhou, W.1
-
28
-
-
84896408214
-
Exosomal HIF1α supports invasive potential of nasopharyngeal carcinoma-associated LMP1-positive exosomes
-
Aga, M., et al. Exosomal HIF1α supports invasive potential of nasopharyngeal carcinoma-associated LMP1-positive exosomes. Oncogene 33 (2014), 4613–4622.
-
(2014)
Oncogene
, vol.33
, pp. 4613-4622
-
-
Aga, M.1
-
29
-
-
84963959740
-
Exosome-transmitted lncARSR promotes sunitinib resistance in renal cancer by acting as a competing endogenous RNA
-
Qu, L., et al. Exosome-transmitted lncARSR promotes sunitinib resistance in renal cancer by acting as a competing endogenous RNA. Cancer Cell 29 (2016), 653–668.
-
(2016)
Cancer Cell
, vol.29
, pp. 653-668
-
-
Qu, L.1
-
30
-
-
84946559154
-
Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth
-
Zhang, L., et al. Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth. Nature 527 (2015), 100–104.
-
(2015)
Nature
, vol.527
, pp. 100-104
-
-
Zhang, L.1
-
31
-
-
84978054068
-
Oncogene knockdown via active loading of small RNAs into extracellular vesicles by sonication
-
Lamichhane, T.N., et al. Oncogene knockdown via active loading of small RNAs into extracellular vesicles by sonication. Cell. Mol. Bioeng. 9 (2016), 315–324.
-
(2016)
Cell. Mol. Bioeng.
, vol.9
, pp. 315-324
-
-
Lamichhane, T.N.1
-
32
-
-
84979947914
-
Evolving landscape of tumor molecular profiling for personalized cancer therapy: a comprehensive review
-
Syn, N.L.-X., et al. Evolving landscape of tumor molecular profiling for personalized cancer therapy: a comprehensive review. Expert Opin. Drug Metab. Toxicol. 12 (2016), 911–922.
-
(2016)
Expert Opin. Drug Metab. Toxicol.
, vol.12
, pp. 911-922
-
-
Syn, N.L.-X.1
-
33
-
-
84964597343
-
Dendritic cell-derived exosomes for cancer therapy
-
Pitt, J.M., et al. Dendritic cell-derived exosomes for cancer therapy. J. Clin. Invest. 126 (2016), 1224–1232.
-
(2016)
J. Clin. Invest.
, vol.126
, pp. 1224-1232
-
-
Pitt, J.M.1
-
34
-
-
84866152581
-
Immune surveillance properties of human NK cell-derived exosomes
-
Lugini, L., et al. Immune surveillance properties of human NK cell-derived exosomes. J. Immunol. 189 (2012), 2833–2842.
-
(2012)
J. Immunol.
, vol.189
, pp. 2833-2842
-
-
Lugini, L.1
-
35
-
-
84905052545
-
Tumour-derived exosomes as antigen delivery carriers in dendritic cell-based immunotherapy for malignant mesothelioma
-
Mahaweni, N.M., et al. Tumour-derived exosomes as antigen delivery carriers in dendritic cell-based immunotherapy for malignant mesothelioma. J. Extracell. Vesicles, 2, 2013, 22492.
-
(2013)
J. Extracell. Vesicles
, vol.2
, pp. 22492
-
-
Mahaweni, N.M.1
-
36
-
-
84982816185
-
Exosomes derived from tumor cells genetically modified to express Mycobacterium tuberculosis antigen: a novel vaccine for cancer therapy
-
Koyama, Y., et al. Exosomes derived from tumor cells genetically modified to express Mycobacterium tuberculosis antigen: a novel vaccine for cancer therapy. Biotechnol. Lett. 38 (2016), 1857–1866.
-
(2016)
Biotechnol. Lett.
, vol.38
, pp. 1857-1866
-
-
Koyama, Y.1
-
37
-
-
84918815052
-
Improved vaccine efficacy of tumor exosome compared to tumor lysate loaded dendritic cells in mice
-
Gu, X., et al. Improved vaccine efficacy of tumor exosome compared to tumor lysate loaded dendritic cells in mice. Int. J. Cancer 136 (2015), E74–E84.
-
(2015)
Int. J. Cancer
, vol.136
, pp. E74-E84
-
-
Gu, X.1
-
38
-
-
84991029161
-
RIG-I activation induces the release of extracellular vesicles with antitumor activity
-
Daßler-Plenker, J., RIG-I activation induces the release of extracellular vesicles with antitumor activity. Oncoimmunology, 5, 2016, e1219827.
-
(2016)
Oncoimmunology
, vol.5
, pp. e1219827
-
-
Daßler-Plenker, J.1
-
39
-
-
84875069590
-
Dendritic cell exosomes directly kill tumor cells and activate natural killer cells via TNF superfamily ligands
-
Munich, S., et al. Dendritic cell exosomes directly kill tumor cells and activate natural killer cells via TNF superfamily ligands. Oncoimmunology 1 (2012), 1074–1083.
-
(2012)
Oncoimmunology
, vol.1
, pp. 1074-1083
-
-
Munich, S.1
-
40
-
-
63449129623
-
Dendritic cell-derived exosomes promote natural killer cell activation and proliferation: a role for NKG2D ligands and IL-15Ralpha
-
Viaud, S., et al. Dendritic cell-derived exosomes promote natural killer cell activation and proliferation: a role for NKG2D ligands and IL-15Ralpha. PLoS One, 4, 2009, e4942.
-
(2009)
PLoS One
, vol.4
, pp. e4942
-
-
Viaud, S.1
-
41
-
-
78650672083
-
Updated technology to produce highly immunogenic dendritic cell-derived exosomes of clinical grade: a critical role of Interferon-γ
-
Viaud, S., et al. Updated technology to produce highly immunogenic dendritic cell-derived exosomes of clinical grade: a critical role of Interferon-γ. J. Immunother. 34 (2011), 65–75.
-
(2011)
J. Immunother.
, vol.34
, pp. 65-75
-
-
Viaud, S.1
-
42
-
-
84874903268
-
Dendritic cell-derived exosomes need to activate both T and B cells to induce antitumor immunity
-
Naslund, T.I., et al. Dendritic cell-derived exosomes need to activate both T and B cells to induce antitumor immunity. J. Immunol. 190 (2013), 2712–2719.
-
(2013)
J. Immunol.
, vol.190
, pp. 2712-2719
-
-
Naslund, T.I.1
-
43
-
-
84880049306
-
Synergistic induction of adaptive antitumor immunity by codelivery of antigen with α-galactosylceramide on exosomes
-
Gehrmann, U., et al. Synergistic induction of adaptive antitumor immunity by codelivery of antigen with α-galactosylceramide on exosomes. Cancer Res. 73 (2013), 3865–3876.
-
(2013)
Cancer Res.
, vol.73
, pp. 3865-3876
-
-
Gehrmann, U.1
-
44
-
-
84949255545
-
TLR-3 stimulation improves anti-tumor immunity elicited by dendritic cell exosome-based vaccines in a murine model of melanoma
-
Damo, M., et al. TLR-3 stimulation improves anti-tumor immunity elicited by dendritic cell exosome-based vaccines in a murine model of melanoma. Sci. Rep., 5, 2015, 17622.
-
(2015)
Sci. Rep.
, vol.5
, pp. 17622
-
-
Damo, M.1
-
45
-
-
84929272789
-
Dendritic cell-derived exosomes may be a tool for cancer immunotherapy by converting tumor cells into immunogenic targets
-
Romagnoli, G.G., et al. Dendritic cell-derived exosomes may be a tool for cancer immunotherapy by converting tumor cells into immunogenic targets. Front. Immunol., 5, 2014, 692.
-
(2014)
Front. Immunol.
, vol.5
, pp. 692
-
-
Romagnoli, G.G.1
-
46
-
-
84875069590
-
Dendritic cell exosomes directly kill tumor cells and activate natural killer cells via TNF superfamily ligands
-
Munich, S., et al. Dendritic cell exosomes directly kill tumor cells and activate natural killer cells via TNF superfamily ligands. Oncoimmunology 1 (2012), 1074–1083.
-
(2012)
Oncoimmunology
, vol.1
, pp. 1074-1083
-
-
Munich, S.1
-
47
-
-
18144372419
-
Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial
-
Escudier, B., et al. Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial. J. Transl. Med., 3, 2005, 10.
-
(2005)
J. Transl. Med.
, vol.3
, pp. 10
-
-
Escudier, B.1
-
48
-
-
18144369346
-
A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer
-
Morse, M.A., et al. A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer. J. Transl. Med., 3, 2005, 9.
-
(2005)
J. Transl. Med.
, vol.3
, pp. 9
-
-
Morse, M.A.1
-
49
-
-
84962844515
-
Dendritic cell-derived exosomes as maintenance immunotherapy after first line chemotherapy in NSCLC
-
Besse, B., et al. Dendritic cell-derived exosomes as maintenance immunotherapy after first line chemotherapy in NSCLC. Oncoimmunology, 5, 2016, e1071008.
-
(2016)
Oncoimmunology
, vol.5
, pp. e1071008
-
-
Besse, B.1
-
50
-
-
85020602339
-
The National University Cancer Institute, Singapore (NCIS) Integrated Molecular Analysis of Cancer (IMAC) precision oncology programme: frequency of actionable mutations and outcomes following matched therapy in an Asian Cancer Centre
-
mdw579.001
-
Syn, N., et al. The National University Cancer Institute, Singapore (NCIS) Integrated Molecular Analysis of Cancer (IMAC) precision oncology programme: frequency of actionable mutations and outcomes following matched therapy in an Asian Cancer Centre. Ann. Oncol., 27, 2016 mdw579.001.
-
(2016)
Ann. Oncol.
, vol.27
-
-
Syn, N.1
-
51
-
-
84992411227
-
Molecular profiling of advanced solid tumors and patient outcomes with genotype-matched clinical trials: the Princess Margaret IMPACT/COMPACT trial
-
Stockley, T.L., et al. Molecular profiling of advanced solid tumors and patient outcomes with genotype-matched clinical trials: the Princess Margaret IMPACT/COMPACT trial. Genome Med., 8, 2016, 109.
-
(2016)
Genome Med.
, vol.8
, pp. 109
-
-
Stockley, T.L.1
-
52
-
-
84992138510
-
Association of biomarker-based treatment strategies with response rates and progression-free survival in refractory malignant neoplasms
-
Schwaederle, M., et al. Association of biomarker-based treatment strategies with response rates and progression-free survival in refractory malignant neoplasms. JAMA Oncol., 2, 2016, 1452.
-
(2016)
JAMA Oncol.
, vol.2
, pp. 1452
-
-
Schwaederle, M.1
-
53
-
-
85009877249
-
Surface glycoproteins of exosomes shed by myeloid-derived suppressor cells contribute to function
-
Chauhan, S., et al. Surface glycoproteins of exosomes shed by myeloid-derived suppressor cells contribute to function. J. Proteome Res. 16 (2016), 238–246.
-
(2016)
J. Proteome Res.
, vol.16
, pp. 238-246
-
-
Chauhan, S.1
-
54
-
-
85015311981
-
High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources
-
Haraszti, R.A., et al. High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources. J. Extracell. Vesicles, 5, 2016, 32570.
-
(2016)
J. Extracell. Vesicles
, vol.5
, pp. 32570
-
-
Haraszti, R.A.1
-
55
-
-
84908036925
-
Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro
-
Smyth, T.J., et al. Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro. Biochim. Biophys. Acta 1838 (2014), 2954–2965.
-
(2014)
Biochim. Biophys. Acta
, vol.1838
, pp. 2954-2965
-
-
Smyth, T.J.1
-
56
-
-
84919725071
-
Biodistribution and delivery efficiency of unmodified tumor-derived exosomes
-
Smyth, T., et al. Biodistribution and delivery efficiency of unmodified tumor-derived exosomes. J. Control. Release 199 (2015), 145–155.
-
(2015)
J. Control. Release
, vol.199
, pp. 145-155
-
-
Smyth, T.1
-
57
-
-
85016490706
-
Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting
-
Wiklander, O.P.B., Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting. J. Extracell. Vesicles, 4, 2015, 26316.
-
(2015)
J. Extracell. Vesicles
, vol.4
, pp. 26316
-
-
Wiklander, O.P.B.1
-
58
-
-
85020648971
-
Single exosome study reveals subpopulations distributed among cell lines with variability related to membrane content
-
Smith, Z.J., et al. Single exosome study reveals subpopulations distributed among cell lines with variability related to membrane content. J. Extracell. Vesicles, 4, 2015, 28533.
-
(2015)
J. Extracell. Vesicles
, vol.4
, pp. 28533
-
-
Smith, Z.J.1
-
59
-
-
84870575710
-
Exosome-mediated delivery of siRNA in vitro and in vivo
-
El-Andaloussi, S., Exosome-mediated delivery of siRNA in vitro and in vivo. Nat. Protoc. 7 (2012), 2112–2126.
-
(2012)
Nat. Protoc.
, vol.7
, pp. 2112-2126
-
-
El-Andaloussi, S.1
-
60
-
-
84978404140
-
Display of GPI-anchored anti-EGFR nanobodies on extracellular vesicles promotes tumour cell targeting
-
Kooijmans, S.A.A., Display of GPI-anchored anti-EGFR nanobodies on extracellular vesicles promotes tumour cell targeting. J. Extracell. Vesicles, 5, 2016, 31053.
-
(2016)
J. Extracell. Vesicles
, vol.5
, pp. 31053
-
-
Kooijmans, S.A.A.1
-
61
-
-
84981306115
-
Efficient production and enhanced tumor delivery of engineered extracellular vesicles
-
Watson, D.C., et al. Efficient production and enhanced tumor delivery of engineered extracellular vesicles. Biomaterials 105 (2016), 195–205.
-
(2016)
Biomaterials
, vol.105
, pp. 195-205
-
-
Watson, D.C.1
-
62
-
-
84954472576
-
PEGylated and targeted extracellular vesicles display enhanced cell specificity and circulation time
-
Kooijmans, S.A.A., PEGylated and targeted extracellular vesicles display enhanced cell specificity and circulation time. J. Control. Release 224 (2016), 77–85.
-
(2016)
J. Control. Release
, vol.224
, pp. 77-85
-
-
Kooijmans, S.A.A.1
-
63
-
-
84961885150
-
Blood exosomes endowed with magnetic and targeting properties for cancer therapy
-
Qi, H., et al. Blood exosomes endowed with magnetic and targeting properties for cancer therapy. ACS Nano 10 (2016), 3323–3333.
-
(2016)
ACS Nano
, vol.10
, pp. 3323-3333
-
-
Qi, H.1
-
64
-
-
84884187644
-
Electroporation-induced siRNA precipitation obscures the efficiency of siRNA loading into extracellular vesicles
-
Kooijmans, S.A.A., Electroporation-induced siRNA precipitation obscures the efficiency of siRNA loading into extracellular vesicles. J. Control. Release 172 (2013), 229–238.
-
(2013)
J. Control. Release
, vol.172
, pp. 229-238
-
-
Kooijmans, S.A.A.1
-
65
-
-
84960907941
-
Exogenous DNA loading into extracellular vesicles via electroporation is size-dependent and enables limited gene delivery
-
Lamichhane, T.N., et al. Exogenous DNA loading into extracellular vesicles via electroporation is size-dependent and enables limited gene delivery. Mol. Pharm. 12 (2015), 3650–3657.
-
(2015)
Mol. Pharm.
, vol.12
, pp. 3650-3657
-
-
Lamichhane, T.N.1
-
66
-
-
84957697095
-
Evaluation of electroporation-induced adverse effects on adipose-derived stem cell exosomes
-
Johnsen, K.B., et al. Evaluation of electroporation-induced adverse effects on adipose-derived stem cell exosomes. Cytotechnology 68 (2016), 2125–2138.
-
(2016)
Cytotechnology
, vol.68
, pp. 2125-2138
-
-
Johnsen, K.B.1
-
67
-
-
84929166867
-
Liposome-based engineering of cells to package hydrophobic compounds in membrane vesicles for tumor penetration
-
Lee, J., et al. Liposome-based engineering of cells to package hydrophobic compounds in membrane vesicles for tumor penetration. Nano Lett. 15 (2015), 2938–2944.
-
(2015)
Nano Lett.
, vol.15
, pp. 2938-2944
-
-
Lee, J.1
-
68
-
-
84979200310
-
Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein–protein interaction module
-
Yim, N., et al. Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein–protein interaction module. Nat. Commun., 7, 2016, 12277.
-
(2016)
Nat. Commun.
, vol.7
, pp. 12277
-
-
Yim, N.1
-
69
-
-
84929708677
-
Mechanisms of RNA loading into exosomes
-
Janas, T., et al. Mechanisms of RNA loading into exosomes. FEBS Lett. 589 (2015), 1391–1398.
-
(2015)
FEBS Lett.
, vol.589
, pp. 1391-1398
-
-
Janas, T.1
-
70
-
-
84890907806
-
Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs
-
Villarroya-Beltri, C., Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs. Nat. Commun., 4, 2013, 2980.
-
(2013)
Nat. Commun.
, vol.4
, pp. 2980
-
-
Villarroya-Beltri, C.1
-
71
-
-
84978136466
-
Exosomal cancer immunotherapy is independent of MHC molecules on exosomes
-
Hiltbrunner, S., et al. Exosomal cancer immunotherapy is independent of MHC molecules on exosomes. Oncotarget 7 (2016), 38707–38717.
-
(2016)
Oncotarget
, vol.7
, pp. 38707-38717
-
-
Hiltbrunner, S.1
-
72
-
-
84886944553
-
Cancer immunotherapy with exosomes requires B-cell activation
-
Näslund, T.I., et al. Cancer immunotherapy with exosomes requires B-cell activation. Oncoimmunology, 2, 2013, e24533.
-
(2013)
Oncoimmunology
, vol.2
, pp. e24533
-
-
Näslund, T.I.1
-
73
-
-
84978136466
-
Exosomal cancer immunotherapy is independent of MHC molecules on exosomes
-
Hiltbrunner, S., et al. Exosomal cancer immunotherapy is independent of MHC molecules on exosomes. Oncotarget 7 (2016), 38707–38717.
-
(2016)
Oncotarget
, vol.7
, pp. 38707-38717
-
-
Hiltbrunner, S.1
-
74
-
-
84890288535
-
Potentiating antitumor immunity with αGC-loaded exosomes
-
Gehrmann, U., et al. Potentiating antitumor immunity with αGC-loaded exosomes. Oncoimmunology, 2, 2013, e26261.
-
(2013)
Oncoimmunology
, vol.2
, pp. e26261
-
-
Gehrmann, U.1
-
75
-
-
33744817657
-
Intradermal vaccination of dendritic cell-derived exosomes is superior to a subcutaneous one in the induction of antitumor immunity
-
Hao, S., et al. Intradermal vaccination of dendritic cell-derived exosomes is superior to a subcutaneous one in the induction of antitumor immunity. Cancer Biother. Radiopharm. 21 (2006), 146–154.
-
(2006)
Cancer Biother. Radiopharm.
, vol.21
, pp. 146-154
-
-
Hao, S.1
-
76
-
-
84964211348
-
Lymphatic transport of exosomes as a rapid route of information dissemination to the lymph node
-
Srinivasan, S., et al. Lymphatic transport of exosomes as a rapid route of information dissemination to the lymph node. Sci. Rep., 6, 2016, 24436.
-
(2016)
Sci. Rep.
, vol.6
, pp. 24436
-
-
Srinivasan, S.1
-
77
-
-
84956943692
-
Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper
-
Lener, T., et al. Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper. J. Extracell. Vesicles, 4, 2015, 30087.
-
(2015)
J. Extracell. Vesicles
, vol.4
, pp. 30087
-
-
Lener, T.1
-
78
-
-
85016350463
-
Analysis of nanoparticle delivery to tumours
-
Wilhelm, S., et al. Analysis of nanoparticle delivery to tumours. Nat. Rev. Mater., 1, 2016, 16014.
-
(2016)
Nat. Rev. Mater.
, vol.1
, pp. 16014
-
-
Wilhelm, S.1
-
79
-
-
84874988827
-
Mesenchymal stem cell: an efficient mass producer of exosomes for drug delivery
-
Yeo, R.W.Y., et al. Mesenchymal stem cell: an efficient mass producer of exosomes for drug delivery. Adv. Drug Deliv. Rev. 65 (2013), 336–341.
-
(2013)
Adv. Drug Deliv. Rev.
, vol.65
, pp. 336-341
-
-
Yeo, R.W.Y.1
-
80
-
-
84990304468
-
Optimized exosome isolation protocol for cell culture supernatant and human plasma
-
Lobb, R.J., et al. Optimized exosome isolation protocol for cell culture supernatant and human plasma. J. Extracell. Vesicles, 4, 2015, 27031.
-
(2015)
J. Extracell. Vesicles
, vol.4
, pp. 27031
-
-
Lobb, R.J.1
-
81
-
-
84975790728
-
Different EV enrichment methods suitable for clinical settings yield different subpopulations of urinary extracellular vesicles from human samples
-
Royo, F., et al. Different EV enrichment methods suitable for clinical settings yield different subpopulations of urinary extracellular vesicles from human samples. J. Extracell. Vesicles, 5, 2016, 29497.
-
(2016)
J. Extracell. Vesicles
, vol.5
, pp. 29497
-
-
Royo, F.1
-
82
-
-
84980368129
-
Nanoscale lateral displacement arrays for the separation of exosomes and colloids down to 20 nm
-
Wunsch, B.H., et al. Nanoscale lateral displacement arrays for the separation of exosomes and colloids down to 20 nm. Nat. Nanotechnol. 11 (2016), 936–940.
-
(2016)
Nat. Nanotechnol.
, vol.11
, pp. 936-940
-
-
Wunsch, B.H.1
-
83
-
-
84943166389
-
Microfluidic size separation of cells and particles using a swinging bucket centrifuge
-
Yeo, J.C., et al. Microfluidic size separation of cells and particles using a swinging bucket centrifuge. Biomicrofluidics, 9, 2015, 54114.
-
(2015)
Biomicrofluidics
, vol.9
, pp. 54114
-
-
Yeo, J.C.1
-
84
-
-
84879926621
-
Ciliated micropillars for the microfluidic-based isolation of nanoscale lipid vesicles
-
Wang, Z., et al. Ciliated micropillars for the microfluidic-based isolation of nanoscale lipid vesicles. Lab Chip, 13, 2013, 2879.
-
(2013)
Lab Chip
, vol.13
, pp. 2879
-
-
Wang, Z.1
-
85
-
-
84925655299
-
Acoustic purification of extracellular microvesicles
-
Lee, K., et al. Acoustic purification of extracellular microvesicles. ACS Nano 9 (2015), 2321–2327.
-
(2015)
ACS Nano
, vol.9
, pp. 2321-2327
-
-
Lee, K.1
-
86
-
-
84969317407
-
Handling and storage of human body fluids for analysis of extracellular vesicles
-
Yuana, Y., et al. Handling and storage of human body fluids for analysis of extracellular vesicles. J. Extracell. Vesicles, 4, 2015, 29260.
-
(2015)
J. Extracell. Vesicles
, vol.4
, pp. 29260
-
-
Yuana, Y.1
|