Biodistribution and delivery efficiency of unmodified tumor-derived exosomes

Journal of Controlled Release

Volumn 199, Issue , 2015, Pages 145-155

  Smyth, Tyson ^a   Kullberg, Max ^a   Malik, Noeen ^b   Smith Jones, Peter ^c   Graner, Michael W ^d   Anchordoquy, Thomas J ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY HOSPITAL ULM   (Germany)

^c STONY BROOK UNIVERSITY   (United States)

^d UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Biodistribution; Exosomes; Intratumoral injection; Intravenous injection; Liposomes

Indexed keywords

DRUG DELIVERY; IMMUNE SYSTEM; LIPOSOMES; PROTEINS;

ANTI-CANCER DRUG DELIVERY; BIODISTRIBUTIONS; DRUG DELIVERY VEHICLES; EXOSOMES; INNATE IMMUNE SYSTEMS; INTRATUMORAL INJECTION; INTRAVENOUS INJECTIONS; LIPOSOMAL FORMULATION;

TUMORS;

DOXORUBICIN; DRUG VEHICLE; LIPID; LIPOSOME; PHOSPHATIDYLCHOLINE; SYNTHETIC EXOSOMES LIPOSOME; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; ANTINEOPLASTIC ANTIBIOTIC; CHOLINE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG RELEASE; EXOSOME; EXTRACTION; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NONHUMAN; TUMOR DERIVED EXOSOME; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; CHEMISTRY; INTRAVENOUS DRUG ADMINISTRATION; MEDICINAL CHEMISTRY; METABOLISM; NEOPLASM; PARTICLE SIZE; TISSUE DISTRIBUTION;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; CELL LINE; CHEMISTRY, PHARMACEUTICAL; CHOLINE; DOXORUBICIN; DRUG DELIVERY SYSTEMS; EXOSOMES; INJECTIONS, INTRAVENOUS; LIPOSOMES; MICE; MICE, INBRED BALB C; NEOPLASMS; PARTICLE SIZE; PHARMACEUTICAL VEHICLES; PHOSPHATIDYLCHOLINES; TISSUE DISTRIBUTION;

EID: 84919725071     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.12.013     Document Type: Article

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