Efficient production and enhanced tumor delivery of engineered extracellular vesicles

Biomaterials

Volumn 105, Issue , 2016, Pages 195-205

  Watson, Dionysios C ^a   Bayik, Defne ^a,b   Srivatsan, Avinash ^c   Bergamaschi, Cristina ^a   Valentin, Antonio ^a   Niu, Gang ^c   Bear, Jenifer ^a   Monninger, Mitchell ^d   Sun, Mei ^d   Morales Kastresana, Aizea ^e   Jones, Jennifer C ^e   Felber, Barbara K ^a   Chen, Xiaoyuan ^c   Gursel, Ihsan ^b   Pavlakis, George N ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b BILKENT UNIVERSITY   (Turkey)

^c NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING   (United States)

^d UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Biodistribution; Dextran sulfate; Drug delivery; Exosomes; Reticuloendothelial system; Scavenger receptor

Indexed keywords

BIOREACTORS; BODY FLUIDS; CELL CULTURE; DEXTRAN; DRUG DELIVERY; MOLECULAR BIOLOGY; TUMORS;

BIODISTRIBUTIONS; DEXTRAN SULFATES; EXOSOMES; RETICULOENDOTHELIAL SYSTEMS; SCAVENGER RECEPTOR;

BIOCONVERSION;

CHONDROITIN; DEXTRAN SULFATE; INTERLEUKIN 15; INTERLEUKIN 15 RECEPTOR ALPHA; SCAVENGER RECEPTOR A; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOREACTOR; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; EXOSOME; HEK293 CELL LINE; HEPATIC CLEARANCE; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEOMICS; BATCH CELL CULTURE; CELL CULTURE; CELL FRACTIONATION; DEVICES; EQUIPMENT DESIGN; EXPERIMENTAL NEOPLASM; HUMAN; METABOLISM; PHYSIOLOGY; PROCEDURES; TISSUE ENGINEERING; ULTRASTRUCTURE;

BATCH CELL CULTURE TECHNIQUES; BIOREACTORS; CELL FRACTIONATION; CELLS, CULTURED; EQUIPMENT DESIGN; EXTRACELLULAR VESICLES; HEK293 CELLS; HUMANS; MACROPHAGES; NEOPLASMS, EXPERIMENTAL; TISSUE ENGINEERING;

EID: 84981306115     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2016.07.003     Document Type: Article

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