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Volumn 37, Issue 7, 2016, Pages 606-617

Exosome-Mediated Metastasis: From Epithelial-Mesenchymal Transition to Escape from Immunosurveillance

Author keywords

[No Author keywords available]

Indexed keywords

5' NUCLEOTIDASE; BETA CATENIN; CAVEOLIN 1; CD39 ANTIGEN; CURCUMIN; HEPARANASE; HEPARANASE INHIBITOR; HEPARIN; HEPARIN DERIVATIVE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTEGRIN; PROTON PUMP INHIBITOR; SYNDECAN 1; TRANSFORMING GROWTH FACTOR BETA; VORINOSTAT;

EID: 84964853782     PISSN: 01656147     EISSN: 18733735     Source Type: Journal    
DOI: 10.1016/j.tips.2016.04.006     Document Type: Review
Times cited : (419)

References (80)
  • 1
    • 50549121134 scopus 로고
    • The distribution of secondary growths in cancer of the breast
    • S. Paget The distribution of secondary growths in cancer of the breast Lancet 133 1889 571 573
    • (1889) Lancet , vol.133 , pp. 571-573
    • Paget, S.1
  • 2
    • 84911966357 scopus 로고    scopus 로고
    • Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis
    • S.A. Melo, and et al. Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis Cancer Cell 26 2014 707 721
    • (2014) Cancer Cell , vol.26 , pp. 707-721
    • Melo, S.A.1
  • 3
    • 84881113880 scopus 로고    scopus 로고
    • Modulation of B-cell exosome proteins by gamma herpesvirus infection
    • D.G. Meckes, and et al. Modulation of B-cell exosome proteins by gamma herpesvirus infection Proc. Natl. Acad. Sci. U.S.A. 110 2013 E2925 E2933
    • (2013) Proc. Natl. Acad. Sci. U.S.A. , vol.110 , pp. E2925-E2933
    • Meckes, D.G.1
  • 4
    • 84864503916 scopus 로고    scopus 로고
    • MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response
    • M. Fabbri, and et al. MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response Proc. Natl. Acad. Sci. U.S.A. 109 2012 E2110 E2116
    • (2012) Proc. Natl. Acad. Sci. U.S.A. , vol.109 , pp. E2110-E2116
    • Fabbri, M.1
  • 5
    • 84898476721 scopus 로고    scopus 로고
    • Cancer-secreted MIR-105 destroys vascular endothelial barriers to promote metastasis
    • W. Zhou, and et al. Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis Cancer Cell 25 2014 501 515
    • (2014) Cancer Cell , vol.25 , pp. 501-515
    • Zhou, W.1
  • 6
    • 84896408214 scopus 로고    scopus 로고
    • Exosomal HIF1α supports invasive potential of nasopharyngeal carcinoma-associated LMP1-positive exosomes
    • M. Aga, and et al. Exosomal HIF1α supports invasive potential of nasopharyngeal carcinoma-associated LMP1-positive exosomes Oncogene 33 2014 4613 4622
    • (2014) Oncogene , vol.33 , pp. 4613-4622
    • Aga, M.1
  • 7
    • 84930225521 scopus 로고    scopus 로고
    • In vivo imaging reveals extracellular vesicle-mediated phenocopying of metastatic behavior
    • A. Zomer, and et al. In vivo imaging reveals extracellular vesicle-mediated phenocopying of metastatic behavior Cell 161 2015 1046 1057
    • (2015) Cell , vol.161 , pp. 1046-1057
    • Zomer, A.1
  • 8
    • 84872534918 scopus 로고    scopus 로고
    • RNA trafficking by acute myelogenous leukemia exosomes
    • J. Huan, and et al. RNA trafficking by acute myelogenous leukemia exosomes Cancer Res. 73 2013 918 929
    • (2013) Cancer Res. , vol.73 , pp. 918-929
    • Huan, J.1
  • 9
    • 84896323201 scopus 로고    scopus 로고
    • Neoplastic reprogramming of patient-derived adipose stem cells by prostate cancer cell-associated exosomes
    • Z.Y. Abd Elmageed, and et al. Neoplastic reprogramming of patient-derived adipose stem cells by prostate cancer cell-associated exosomes Stem Cells 32 2014 983 997
    • (2014) Stem Cells , vol.32 , pp. 983-997
    • Abd Elmageed, Z.Y.1
  • 10
    • 84893188871 scopus 로고    scopus 로고
    • Tumor-derived exosomes are enriched in Δnp73, which promotes oncogenic potential in acceptor cells and correlates with patient survival
    • B. Soldevilla, and et al. Tumor-derived exosomes are enriched in ΔNp73, which promotes oncogenic potential in acceptor cells and correlates with patient survival Hum. Mol. Genet. 23 2014 467 478
    • (2014) Hum. Mol. Genet. , vol.23 , pp. 467-478
    • Soldevilla, B.1
  • 11
    • 84983096332 scopus 로고    scopus 로고
    • Matrix metalloproteinase 13-containing exosomes promote nasopharyngeal carcinoma metastasis
    • Y. You, and et al. Matrix metalloproteinase 13-containing exosomes promote nasopharyngeal carcinoma metastasis Cancer Sci. 106 2015 1669 1677
    • (2015) Cancer Sci. , vol.106 , pp. 1669-1677
    • You, Y.1
  • 12
    • 84991017501 scopus 로고    scopus 로고
    • Urothelial cells undergo epithelial-to-mesenchymal transition after exposure to muscle invasive bladder cancer exosomes
    • C.A. Franzen, and et al. Urothelial cells undergo epithelial-to-mesenchymal transition after exposure to muscle invasive bladder cancer exosomes Oncogenesis 4 2015 e163
    • (2015) Oncogenesis , vol.4 , pp. e163
    • Franzen, C.A.1
  • 13
    • 84895744810 scopus 로고    scopus 로고
    • Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors
    • D.K. Jeppesen, and et al. Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors Proteomics 14 2014 699 712
    • (2014) Proteomics , vol.14 , pp. 699-712
    • Jeppesen, D.K.1
  • 14
    • 79953081976 scopus 로고    scopus 로고
    • Interaction and uptake of exosomes by ovarian cancer cells
    • C. Escrevente, and et al. Interaction and uptake of exosomes by ovarian cancer cells BMC Cancer 11 2011 108
    • (2011) BMC Cancer , vol.11 , pp. 108
    • Escrevente, C.1
  • 15
    • 84862007577 scopus 로고    scopus 로고
    • Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
    • H. Peinado, and et al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET Nat. Med. 18 2012 883 891
    • (2012) Nat. Med. , vol.18 , pp. 883-891
    • Peinado, H.1
  • 16
    • 79957879331 scopus 로고    scopus 로고
    • Exosomes released by melanoma cells prepare sentinel lymph nodes for tumor metastasis
    • J.L. Hood, and et al. Exosomes released by melanoma cells prepare sentinel lymph nodes for tumor metastasis Cancer Res. 71 2011 3792 3801
    • (2011) Cancer Res. , vol.71 , pp. 3792-3801
    • Hood, J.L.1
  • 17
    • 84930170395 scopus 로고    scopus 로고
    • Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
    • B. Costa-Silva, and et al. Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver Nat. Cell Biol. 17 2015 816 826
    • (2015) Nat. Cell Biol. , vol.17 , pp. 816-826
    • Costa-Silva, B.1
  • 18
    • 84906212452 scopus 로고    scopus 로고
    • Tumor-derived exosomes promote tumor progression and T-cell dysfunction through the regulation of enriched exosomal microRNAs in human nasopharyngeal carcinoma
    • S-B. Ye, and et al. Tumor-derived exosomes promote tumor progression and T-cell dysfunction through the regulation of enriched exosomal microRNAs in human nasopharyngeal carcinoma Oncotarget 5 2014 5439 5452
    • (2014) Oncotarget , vol.5 , pp. 5439-5452
    • Ye, S.-B.1
  • 19
    • 79960516623 scopus 로고    scopus 로고
    • Cancer exosomes express CD39 and CD73, which suppress T cells through adenosine production
    • A. Clayton, and et al. Cancer exosomes express CD39 and CD73, which suppress T cells through adenosine production J. Immunol. 187 2011 676 683
    • (2011) J. Immunol. , vol.187 , pp. 676-683
    • Clayton, A.1
  • 20
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • J.P. Thiery, and et al. Epithelial-mesenchymal transitions in development and disease Cell 139 2009 871 890
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1
  • 21
    • 84911390789 scopus 로고    scopus 로고
    • Exosome proteomics reveals transcriptional regulator proteins with potential to mediate downstream pathways
    • T.H. Ung, and et al. Exosome proteomics reveals transcriptional regulator proteins with potential to mediate downstream pathways Cancer Sci. 105 2014 1384 1392
    • (2014) Cancer Sci. , vol.105 , pp. 1384-1392
    • Ung, T.H.1
  • 22
    • 84896705882 scopus 로고    scopus 로고
    • Molecular characterization of exosome-like vesicles from breast cancer cells
    • S. Kruger, and et al. Molecular characterization of exosome-like vesicles from breast cancer cells BMC Cancer 14 2014 44
    • (2014) BMC Cancer , vol.14 , pp. 44
    • Kruger, S.1
  • 23
    • 84880038924 scopus 로고    scopus 로고
    • Pathogenic role of Epstein-Barr virus latent membrane protein-1 in the development of nasopharyngeal carcinoma
    • T. Yoshizaki, and et al. Pathogenic role of Epstein-Barr virus latent membrane protein-1 in the development of nasopharyngeal carcinoma Cancer Lett. 337 2013 1 7
    • (2013) Cancer Lett. , vol.337 , pp. 1-7
    • Yoshizaki, T.1
  • 24
    • 84938412771 scopus 로고    scopus 로고
    • KRAS-dependent sorting of miRNA to exosomes
    • D.J. Cha, and et al. KRAS-dependent sorting of miRNA to exosomes Elife 4 2015 e07197
    • (2015) Elife , vol.4 , pp. e07197
    • Cha, D.J.1
  • 25
    • 84930763705 scopus 로고    scopus 로고
    • Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules
    • A. Ramteke, and et al. Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules Mol. Carcinog. 54 2015 554 565
    • (2015) Mol. Carcinog. , vol.54 , pp. 554-565
    • Ramteke, A.1
  • 26
    • 84876927914 scopus 로고    scopus 로고
    • Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development
    • P. Kucharzewska, and et al. Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development Proc. Natl. Acad. Sci. U.S.A. 110 2013 7312 7317
    • (2013) Proc. Natl. Acad. Sci. U.S.A. , vol.110 , pp. 7312-7317
    • Kucharzewska, P.1
  • 27
    • 84975179412 scopus 로고    scopus 로고
    • Exosome transfer from ovarian cancer cells to mesothelial cells promotes cell invasion by upregulating MMP-9 secretion and increasing clearance of mesothelial cells
    • K. Nakamura, and et al. Exosome transfer from ovarian cancer cells to mesothelial cells promotes cell invasion by upregulating MMP-9 secretion and increasing clearance of mesothelial cells Cancer Res. 75 Suppl. 15 2015 5060
    • (2015) Cancer Res. , vol.75 , pp. 5060
    • Nakamura, K.1
  • 28
    • 84923005209 scopus 로고    scopus 로고
    • The tetraspanins CD151 and Tspan8 are essential exosome components for the crosstalk between cancer initiating cells and their surrounding
    • S. Yue, and et al. The tetraspanins CD151 and Tspan8 are essential exosome components for the crosstalk between cancer initiating cells and their surrounding Oncotarget 6 2015 2366 2384
    • (2015) Oncotarget , vol.6 , pp. 2366-2384
    • Yue, S.1
  • 29
    • 79955652381 scopus 로고    scopus 로고
    • Amphiregulin exosomes increase cancer cell invasion
    • J.N. Higginbotham, and et al. Amphiregulin exosomes increase cancer cell invasion Curr. Biol. 21 2011 779 786
    • (2011) Curr. Biol. , vol.21 , pp. 779-786
    • Higginbotham, J.N.1
  • 30
    • 84951032501 scopus 로고    scopus 로고
    • Exosomes enriched in stemness/metastatic-related mRNAS promote oncogenic potential in breast cancer
    • M. Rodríguez, and et al. Exosomes enriched in stemness/metastatic-related mRNAS promote oncogenic potential in breast cancer Oncotarget 6 2015 40575 40587
    • (2015) Oncotarget , vol.6 , pp. 40575-40587
    • Rodríguez, M.1
  • 31
    • 84892607130 scopus 로고    scopus 로고
    • Oncogenic KIT-containing exosomes increase gastrointestinal stromal tumor cell invasion
    • S. Atay, and et al. Oncogenic KIT-containing exosomes increase gastrointestinal stromal tumor cell invasion Proc. Natl. Acad. Sci. U.S.A. 111 2014 711 716
    • (2014) Proc. Natl. Acad. Sci. U.S.A. , vol.111 , pp. 711-716
    • Atay, S.1
  • 32
    • 84975183380 scopus 로고    scopus 로고
    • An angiogenic role of E-cadherin-positive exosomes in ovarian cancer
    • M.K.S. Tang, and A.S.T. Wong An angiogenic role of E-cadherin-positive exosomes in ovarian cancer Cancer Res. 75 Suppl. 15 2015 1035
    • (2015) Cancer Res. , vol.75 , pp. 1035
    • Tang, M.K.S.1    Wong, A.S.T.2
  • 33
    • 84871563123 scopus 로고    scopus 로고
    • Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration
    • V. Luga, and et al. Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration Cell 151 2012 1542 1556
    • (2012) Cell , vol.151 , pp. 1542-1556
    • Luga, V.1
  • 34
    • 84874637012 scopus 로고    scopus 로고
    • Exosomal tumor microRNA modulates premetastatic organ cells
    • S. Rana, and et al. Exosomal tumor microRNA modulates premetastatic organ cells Neoplasia 15 2013 281 295
    • (2013) Neoplasia , vol.15 , pp. 281-295
    • Rana, S.1
  • 35
    • 84947723880 scopus 로고    scopus 로고
    • Tumour exosome integrins determine organotropic metastasis
    • A. Hoshino, and et al. Tumour exosome integrins determine organotropic metastasis Nature 527 2015 329 335
    • (2015) Nature , vol.527 , pp. 329-335
    • Hoshino, A.1
  • 36
    • 84874959843 scopus 로고    scopus 로고
    • Imaging exosome transfer from breast cancer cells to stroma at metastatic sites in orthotopic nude-mouse models
    • A. Suetsugu, and et al. Imaging exosome transfer from breast cancer cells to stroma at metastatic sites in orthotopic nude-mouse models Adv. Drug Deliv. Rev. 65 2013 383 390
    • (2013) Adv. Drug Deliv. Rev. , vol.65 , pp. 383-390
    • Suetsugu, A.1
  • 37
    • 84908036925 scopus 로고    scopus 로고
    • Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro
    • T.J. Smyth, and et al. Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro Biochim. Biophys. Acta 1838 2014 2954 2965
    • (2014) Biochim. Biophys. Acta , vol.1838 , pp. 2954-2965
    • Smyth, T.J.1
  • 38
    • 84919725071 scopus 로고    scopus 로고
    • Biodistribution and delivery efficiency of unmodified tumor-derived exosomes
    • T. Smyth, and et al. Biodistribution and delivery efficiency of unmodified tumor-derived exosomes J. Control. Release 199 2015 145 155
    • (2015) J. Control. Release , vol.199 , pp. 145-155
    • Smyth, T.1
  • 39
    • 46049109335 scopus 로고    scopus 로고
    • Tumor lymphangiogenesis and melanoma metastasis
    • M. Rinderknecht, and M. Detmar Tumor lymphangiogenesis and melanoma metastasis J. Cell. Physiol. 216 2008 347 354
    • (2008) J. Cell. Physiol. , vol.216 , pp. 347-354
    • Rinderknecht, M.1    Detmar, M.2
  • 40
    • 84962009930 scopus 로고    scopus 로고
    • Activation of hematopoietic stem/progenitor cells promotes immunosuppression within the pre-metastatic niche
    • Published online December 30, 2015
    • A.J. Giles, and et al. Activation of hematopoietic stem/progenitor cells promotes immunosuppression within the pre-metastatic niche Cancer Res. 2015 Published online December 30, 2015 http://dx.doi.org/10.1158/0008-5472
    • (2015) Cancer Res.
    • Giles, A.J.1
  • 41
    • 84921709757 scopus 로고    scopus 로고
    • Cancer exosomes trigger mesenchymal stem cell differentiation into pro-angiogenic and pro-invasive myofibroblasts
    • R. Chowdhury, and et al. Cancer exosomes trigger mesenchymal stem cell differentiation into pro-angiogenic and pro-invasive myofibroblasts Oncotarget 6 2015 715 731
    • (2015) Oncotarget , vol.6 , pp. 715-731
    • Chowdhury, R.1
  • 42
    • 57749169272 scopus 로고    scopus 로고
    • Tetraspanins: Push and pull in suppressing and promoting metastasis
    • M. Zöller Tetraspanins: push and pull in suppressing and promoting metastasis Nat. Rev. Cancer 9 2009 40 55
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 40-55
    • Zöller, M.1
  • 43
    • 80052446161 scopus 로고    scopus 로고
    • Detachment of breast tumor cells induces rapid secretion of exosomes which subsequently mediate cellular adhesion and spreading
    • R.B. Koumangoye, and et al. Detachment of breast tumor cells induces rapid secretion of exosomes which subsequently mediate cellular adhesion and spreading PLoS ONE 6 2011 e24234
    • (2011) PLoS ONE , vol.6 , pp. e24234
    • Koumangoye, R.B.1
  • 44
    • 84883301160 scopus 로고    scopus 로고
    • Exosomes derived from Epstein-Barr virus-infected cells are internalized via caveola-dependent endocytosis and promote phenotypic modulation in target cells
    • A. Nanbo, and et al. Exosomes derived from Epstein-Barr virus-infected cells are internalized via caveola-dependent endocytosis and promote phenotypic modulation in target cells J. Virol. 87 2013 10334 10347
    • (2013) J. Virol. , vol.87 , pp. 10334-10347
    • Nanbo, A.1
  • 45
    • 85013654823 scopus 로고    scopus 로고
    • Routes and mechanisms of extracellular vesicle uptake
    • L.A. Mulcahy, and et al. Routes and mechanisms of extracellular vesicle uptake J. Extracell. Vesicles 3 2014 24641
    • (2014) J. Extracell. Vesicles , vol.3 , pp. 24641
    • Mulcahy, L.A.1
  • 46
    • 84925446437 scopus 로고    scopus 로고
    • Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes
    • J.P. Webber, and et al. Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes Oncogene 34 2015 290 302
    • (2015) Oncogene , vol.34 , pp. 290-302
    • Webber, J.P.1
  • 47
    • 78649958307 scopus 로고    scopus 로고
    • Cancer exosomes trigger fibroblast to myofibroblast differentiation
    • J. Webber, and et al. Cancer exosomes trigger fibroblast to myofibroblast differentiation Cancer Res. 70 2010 9621 9630
    • (2010) Cancer Res. , vol.70 , pp. 9621-9630
    • Webber, J.1
  • 48
    • 84871451335 scopus 로고    scopus 로고
    • Gastric cancer exosomes trigger differentiation of umbilical cord derived mesenchymal stem cells to carcinoma-associated fibroblasts through TGF-β/Smad pathway
    • J. Gu, and et al. Gastric cancer exosomes trigger differentiation of umbilical cord derived mesenchymal stem cells to carcinoma-associated fibroblasts through TGF-β/Smad pathway PLoS ONE 7 2012 e52465
    • (2012) PLoS ONE , vol.7 , pp. e52465
    • Gu, J.1
  • 49
    • 84957989918 scopus 로고    scopus 로고
    • Exosomes from bulk and stem cells from human prostate cancer have a differential microRNA content that contributes cooperatively over local and pre-metastatic niche
    • C.A. Sánchez, and et al. Exosomes from bulk and stem cells from human prostate cancer have a differential microRNA content that contributes cooperatively over local and pre-metastatic niche Oncotarget 7 2015 3993 4008
    • (2015) Oncotarget , vol.7 , pp. 3993-4008
    • Sánchez, C.A.1
  • 50
    • 84942457204 scopus 로고    scopus 로고
    • Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts
    • J. Paggetti, and et al. Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts Blood 126 2015 1106 1117
    • (2015) Blood , vol.126 , pp. 1106-1117
    • Paggetti, J.1
  • 51
    • 84946559154 scopus 로고    scopus 로고
    • Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth
    • L. Zhang, and et al. Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth Nature 527 2015 100 104
    • (2015) Nature , vol.527 , pp. 100-104
    • Zhang, L.1
  • 52
    • 78650553841 scopus 로고    scopus 로고
    • Human tumor virus utilizes exosomes for intercellular communication
    • D.G. Meckes, and et al. Human tumor virus utilizes exosomes for intercellular communication Proc. Natl. Acad. Sci. U.S.A. 107 2010 20370 20375
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 20370-20375
    • Meckes, D.G.1
  • 53
    • 84966593326 scopus 로고    scopus 로고
    • Glioma-derived extracellular vesicles selectively suppress immune responses
    • Published online September 18, 2015
    • J.E. Hellwinkel, and et al. Glioma-derived extracellular vesicles selectively suppress immune responses Neuro Oncol. 2015 Published online September 18, 2015 http://dx.doi.org/10.1093/neuonc/nov170
    • (2015) Neuro Oncol.
    • Hellwinkel, J.E.1
  • 54
    • 84873149964 scopus 로고    scopus 로고
    • Immune modulation of T-cell and NK (natural killer) cell activities by TEXs (tumour-derived exosomes)
    • T.L. Whiteside Immune modulation of T-cell and NK (natural killer) cell activities by TEXs (tumour-derived exosomes) Biochem. Soc. Trans. 41 2013 245 251
    • (2013) Biochem. Soc. Trans. , vol.41 , pp. 245-251
    • Whiteside, T.L.1
  • 55
    • 84957599052 scopus 로고    scopus 로고
    • Tumor-derived exosomes regulate expression of immune function-related genes in human T cell subsets
    • L. Muller, and et al. Tumor-derived exosomes regulate expression of immune function-related genes in human T cell subsets Sci. Rep. 6 2016 20254
    • (2016) Sci. Rep. , vol.6 , pp. 20254
    • Muller, L.1
  • 56
    • 84925546909 scopus 로고    scopus 로고
    • Effect of nasopharyngeal carcinoma-derived exosomes on human regulatory T cells
    • D. Mrizak, and et al. Effect of nasopharyngeal carcinoma-derived exosomes on human regulatory T cells J. Natl. Cancer Inst. 107 2015 363
    • (2015) J. Natl. Cancer Inst. , vol.107 , pp. 363
    • Mrizak, D.1
  • 57
    • 79955548092 scopus 로고    scopus 로고
    • Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC
    • C. Battke, and et al. Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC Cancer Immunol. Immunother. 60 2011 639 648
    • (2011) Cancer Immunol. Immunother. , vol.60 , pp. 639-648
    • Battke, C.1
  • 58
    • 80053067140 scopus 로고    scopus 로고
    • Exosomal evasion of humoral immunotherapy in aggressive B-cell lymphoma modulated by ATP-binding cassette transporter A3
    • T. Aung, and et al. Exosomal evasion of humoral immunotherapy in aggressive B-cell lymphoma modulated by ATP-binding cassette transporter A3 Proc. Natl. Acad. Sci. U.S.A. 108 2011 15336 15341
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 15336-15341
    • Aung, T.1
  • 59
    • 84904630086 scopus 로고    scopus 로고
    • Macrophage immunomodulation by breast cancer-derived exosomes requires Toll-like receptor 2-mediated activation of NF-κB
    • A. Chow, and et al. Macrophage immunomodulation by breast cancer-derived exosomes requires Toll-like receptor 2-mediated activation of NF-κB Sci. Rep. 4 2014 5750
    • (2014) Sci. Rep. , vol.4 , pp. 5750
    • Chow, A.1
  • 60
    • 85029682480 scopus 로고    scopus 로고
    • Exosomes derived from ascitic fluid of patients with ovarian carcinoma induce IL-4 gene expression in T lymphocytes
    • E. Sahin, and et al. Exosomes derived from ascitic fluid of patients with ovarian carcinoma induce IL-4 gene expression in T lymphocytes Cancer Immunol. Res. 3 Suppl. 10 2015 B82
    • (2015) Cancer Immunol. Res. , vol.3 , pp. B82
    • Sahin, E.1
  • 61
    • 84875994843 scopus 로고    scopus 로고
    • Heparanase regulates secretion, composition, and function of tumor cell-derived exosomes
    • C.A. Thompson, and et al. Heparanase regulates secretion, composition, and function of tumor cell-derived exosomes J. Biol. Chem. 288 2013 10093 10099
    • (2013) J. Biol. Chem. , vol.288 , pp. 10093-10099
    • Thompson, C.A.1
  • 62
    • 84863206297 scopus 로고    scopus 로고
    • Syndecan-syntenin-ALIX regulates the biogenesis of exosomes
    • M.F. Baietti, and et al. Syndecan-syntenin-ALIX regulates the biogenesis of exosomes Nat. Cell Biol. 14 2012 677 685
    • (2012) Nat. Cell Biol. , vol.14 , pp. 677-685
    • Baietti, M.F.1
  • 63
    • 84877694957 scopus 로고    scopus 로고
    • The heparanase/syndecan-1 axis in cancer: Mechanisms and therapies
    • V.C. Ramani, and et al. The heparanase/syndecan-1 axis in cancer: mechanisms and therapies FEBS J. 280 2013 2294 2306
    • (2013) FEBS J. , vol.280 , pp. 2294-2306
    • Ramani, V.C.1
  • 64
    • 36349001899 scopus 로고    scopus 로고
    • +-ATPases as a new strategy against cancer
    • +-ATPases as a new strategy against cancer Cancer Res. 67 2007 10627 10630
    • (2007) Cancer Res. , vol.67 , pp. 10627-10630
    • Fais, S.1
  • 65
    • 33745280126 scopus 로고    scopus 로고
    • The V0-ATPase mediates apical secretion of exosomes containing Hedgehog-related proteins in Caenorhabditis elegans
    • S. Liégeois, and et al. The V0-ATPase mediates apical secretion of exosomes containing Hedgehog-related proteins in Caenorhabditis elegans J. Cell Biol. 173 2006 949 961
    • (2006) J. Cell Biol. , vol.173 , pp. 949-961
    • Liégeois, S.1
  • 66
    • 84895552868 scopus 로고    scopus 로고
    • Exosome release and low pH belong to a framework of resistance of human melanoma cells to cisplatin
    • C. Federici, and et al. Exosome release and low pH belong to a framework of resistance of human melanoma cells to cisplatin PLoS ONE 9 2014 e88193
    • (2014) PLoS ONE , vol.9 , pp. e88193
    • Federici, C.1
  • 67
    • 71749102668 scopus 로고    scopus 로고
    • Microenvironmental pH is a key factor for exosome traffic in tumor cells
    • I. Parolini, and et al. Microenvironmental pH is a key factor for exosome traffic in tumor cells J. Biol. Chem. 284 2009 34211 34222
    • (2009) J. Biol. Chem. , vol.284 , pp. 34211-34222
    • Parolini, I.1
  • 68
    • 84867120348 scopus 로고    scopus 로고
    • Rab27a supports exosome-dependent and -independent mechanisms that modify the tumor microenvironment and can promote tumor progression
    • A. Bobrie, and et al. Rab27a supports exosome-dependent and -independent mechanisms that modify the tumor microenvironment and can promote tumor progression Cancer Res. 72 2012 4920 4930
    • (2012) Cancer Res. , vol.72 , pp. 4920-4930
    • Bobrie, A.1
  • 69
    • 84975172033 scopus 로고    scopus 로고
    • The impact of TSG101 in triple-negative breast cancers
    • S.D.J. Sharma, and et al. The impact of TSG101 in triple-negative breast cancers ASCO Meet. Abstr. 32 Suppl. 15 2014 1114
    • (2014) ASCO Meet. Abstr. , vol.32 , pp. 1114
    • Sharma, S.D.J.1
  • 70
    • 84890238215 scopus 로고    scopus 로고
    • Exosome secretion is enhanced by invadopodia and drives invasive behavior
    • D. Hoshino, and et al. Exosome secretion is enhanced by invadopodia and drives invasive behavior Cell Rep. 5 2013 1159 1168
    • (2013) Cell Rep. , vol.5 , pp. 1159-1168
    • Hoshino, D.1
  • 71
    • 79959541003 scopus 로고    scopus 로고
    • The "ins" and "outs" of podosomes and invadopodia: Characteristics, formation and function
    • D.A. Murphy, and S.A. Courtneidge The "ins" and "outs" of podosomes and invadopodia: characteristics, formation and function Nat. Rev. Mol. Cell Biol. 12 2011 413 426
    • (2011) Nat. Rev. Mol. Cell Biol. , vol.12 , pp. 413-426
    • Murphy, D.A.1    Courtneidge, S.A.2
  • 72
    • 84941338355 scopus 로고    scopus 로고
    • Curcumin modulates pancreatic adenocarcinoma cell-derived exosomal function
    • C.J.D. Osterman, and et al. Curcumin modulates pancreatic adenocarcinoma cell-derived exosomal function PLoS ONE 10 2015 e0132845
    • (2015) PLoS ONE , vol.10 , pp. e0132845
    • Osterman, C.J.D.1
  • 73
    • 34250158095 scopus 로고    scopus 로고
    • Curcumin reverses breast tumor exosomes mediated immune suppression of NK cell tumor cytotoxicity
    • H-G. Zhang, and et al. Curcumin reverses breast tumor exosomes mediated immune suppression of NK cell tumor cytotoxicity Biochim. Biophys. Acta 1773 2007 1116 1123
    • (2007) Biochim. Biophys. Acta , vol.1773 , pp. 1116-1123
    • Zhang, H.-G.1
  • 74
    • 84941241929 scopus 로고    scopus 로고
    • Curcumin inhibits in vitro and in vivo chronic myelogenous leukemia cells growth: A possible role for exosomal disposal of MIR-21
    • S. Taverna, and et al. Curcumin inhibits in vitro and in vivo chronic myelogenous leukemia cells growth: a possible role for exosomal disposal of miR-21 Oncotarget 6 2015 21918 21933
    • (2015) Oncotarget , vol.6 , pp. 21918-21933
    • Taverna, S.1
  • 75
    • 84969895342 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor SAHA induces HSP60 nitration and its extracellular release by exosomal vesicles in human lung-derived carcinoma cells
    • Published online December 19, 2015
    • C. Campanella, and et al. The histone deacetylase inhibitor SAHA induces HSP60 nitration and its extracellular release by exosomal vesicles in human lung-derived carcinoma cells Oncotarget 2015 Published online December 19, 2015 http://dx.doi.org/10.18632/oncotarget.6680
    • (2015) Oncotarget
    • Campanella, C.1
  • 76
    • 84860849807 scopus 로고    scopus 로고
    • Anticancer drugs cause release of exosomes with heat shock proteins from human hepatocellular carcinoma cells that elicit effective natural killer cell antitumor responses in vitro
    • L-H. Lv, and et al. Anticancer drugs cause release of exosomes with heat shock proteins from human hepatocellular carcinoma cells that elicit effective natural killer cell antitumor responses in vitro J. Biol. Chem. 287 2012 15874 15885
    • (2012) J. Biol. Chem. , vol.287 , pp. 15874-15885
    • Lv, L.-H.1
  • 77
    • 84886387008 scopus 로고    scopus 로고
    • Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity
    • H.C. Christianson, and et al. Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity Proc. Natl. Acad. Sci. U.S.A. 110 2013 17380 17385
    • (2013) Proc. Natl. Acad. Sci. U.S.A. , vol.110 , pp. 17380-17385
    • Christianson, H.C.1
  • 78
    • 84959095969 scopus 로고    scopus 로고
    • Application of a persistent heparin treatment inhibits the malignant potential of oral squamous carcinoma cells induced by tumor cell-derived exosomes
    • S. Sento, and et al. Application of a persistent heparin treatment inhibits the malignant potential of oral squamous carcinoma cells induced by tumor cell-derived exosomes PLoS ONE 11 2016 e0148454
    • (2016) PLoS ONE , vol.11 , pp. e0148454
    • Sento, S.1
  • 79
    • 84871923602 scopus 로고    scopus 로고
    • Systemically injected exosomes targeted to EGFR deliver antitumor microRNA to breast cancer cells
    • S. Ohno, and et al. Systemically injected exosomes targeted to EGFR deliver antitumor microRNA to breast cancer cells Mol. Ther. 21 2013 185 191
    • (2013) Mol. Ther. , vol.21 , pp. 185-191
    • Ohno, S.1
  • 80
    • 84936980504 scopus 로고    scopus 로고
    • Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
    • S.A. Melo, and et al. Glypican-1 identifies cancer exosomes and detects early pancreatic cancer Nature 523 2015 177 182
    • (2015) Nature , vol.523 , pp. 177-182
    • Melo, S.A.1


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