Exosome-formed synthetic microRNA-143 is transferred to osteosarcoma cells and inhibits their migration

Biochemical and Biophysical Research Communications

Volumn 445, Issue 2, 2014, Pages 381-387

  Shimbo, Keisuke ^a   Miyaki, Shigeru ^a,b   Ishitobi, Hiroyuki ^b   Kato, Yoshio ^c   Kubo, Tadahiko ^a   Shimose, Shoji ^a   Ochi, Mitsuo ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b HIROSHIMA UNIVERSITY HOSPITAL   (Japan)

^c NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

Delivery system; Exosome; miR 143; Osteosarcoma cells

Indexed keywords

MICRORNA 143;

ARTICLE; CANCER CHEMOTHERAPY; CONCENTRATION RESPONSE; CONTROLLED STUDY; EXOSOME; GENE DELIVERY SYSTEM; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO GENE TRANSFER; MESENCHYMAL STEM CELL; MIGRATION INHIBITION; OSTEOSARCOMA CELL; PRIORITY JOURNAL;

DELIVERY SYSTEM; EXOSOME; MIR-143; OSTEOSARCOMA CELLS;

CELL LINE, TUMOR; CELL MOVEMENT; EXOSOMES; HUMANS; MESENCHYMAL STROMAL CELLS; MICRORNAS; NEOPLASM METASTASIS; OSTEOSARCOMA; TRANSFECTION;

EID: 84896071176     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.02.007     Document Type: Article

References (30)

1. D.S. Geller, and R. Gorlick Osteosarcoma: a review of diagnosis, management, and treatment strategies Clin. Adv. Hematol. Oncol. 8 2010 705 718
2. W.S. Ferguson, and A.M. Goorin Current treatment of osteosarcoma Cancer Invest. 19 2001 292 315 (Pubitemid 32374371)
3. B. Kempf-Bielack, S.S. Bielack, H. Jurgens, D. Branscheid, W.E. Berdel, G.U. Exner, U. Gobel, K. Helmke, G. Jundt, H. Kabisch, M. Kevric, T. Klingebiel, R. Kotz, R. Maas, R. Schwarz, M. Semik, J. Treuner, A. Zoubek, and K. Winkler Osteosarcoma relapse after combined modality therapy: an analysis of unselected patients in the Cooperative Osteosarcoma Study Group (COSS) J. Clin. Oncol. 23 2005 559 568 (Pubitemid 46224233)
4. V. Ambros MicroRNAs: tiny regulators with great potential Cell 107 2001 823 826 (Pubitemid 34084973)
5. D.P. Bartel MicroRNAs: genomics, biogenesis, mechanism, and function Cell 116 2004 281 297
6. B.P. Lewis, C.B. Burge, and D.P. Bartel Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets Cell 120 2005 15 20 (Pubitemid 40094598)
7. G.A. Calin, and C.M. Croce MicroRNA signatures in human cancers Nat. Rev. Cancer 6 2006 857 866 (Pubitemid 44629897)
8. E. Lages, H. Ipas, A. Guttin, H. Nesr, F. Berger, and J.P. Issartel MicroRNAs: molecular features and role in cancer Front. Biosci. (Landmark Ed) 17 2012 2508 2540
9. S. Miyaki, and H. Asahara Macro view of microRNA function in osteoarthritis Nat. Rev. Rheumatol. 8 2012 543 552
10. M. Osaki, F. Takeshita, Y. Sugimoto, N. Kosaka, Y. Yamamoto, Y. Yoshioka, E. Kobayashi, T. Yamada, A. Kawai, T. Inoue, H. Ito, M. Oshimura, and T. Ochiya MicroRNA-143 regulates human osteosarcoma metastasis by regulating matrix metalloprotease-13 expression Mol. Ther. 19 2011 1123 1130
11. H. Zhang, X. Cai, Y. Wang, H. Tang, D. Tong, and F. Ji MicroRNA-143, down-regulated in osteosarcoma, promotes apoptosis and suppresses tumorigenicity by targeting Bcl-2 Oncol. Rep. 24 2010 1363 1369
12. H. Valadi, K. Ekstrom, A. Bossios, M. Sjostrand, J.J. Lee, and J.O. Lotvall Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells Nat. Cell Biol. 9 2007 654 659 (Pubitemid 47214727)
13. G. Camussi, M.C. Deregibus, S. Bruno, C. Grange, V. Fonsato, and C. Tetta Exosome/microvesicle-mediated epigenetic reprogramming of cells Am. J. Cancer Res. 1 2011 98 110
14. C. Yang, and P.D. Robbins The roles of tumor-derived exosomes in cancer pathogenesis Clin. Dev. Immunol. 2011 2011 842849
15. A.V. Vlassov, S. Magdaleno, R. Setterquist, and R. Conrad Exosomes: current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials Biochim. Biophys. Acta 2012 1820 940 948
16. N. Kosaka, H. Iguchi, Y. Yoshioka, F. Takeshita, Y. Matsuki, and T. Ochiya Secretory mechanisms and intercellular transfer of microRNAs in living cells J. Biol. Chem. 285 2010 17442 17452
17. L. Alvarez-Erviti, Y. Seow, H. Yin, C. Betts, S. Lakhal, and M.J. Wood Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes Nat. Biotechnol. 29 2011 341 345
18. L. Yang, M.F. Broom, and I.G. Tucker Characterization of a nanoparticulate drug delivery system using scanning ion occlusion sensing Pharm. Res. 29 2012 2578 2586
19. J. de Vrij, S.L. Maas, M. van Nispen, M. Sena-Esteves, R.W. Limpens, A.J. Koster, S. Leenstra, M.L. Lamfers, and M.L. Broekman Quantification of nanosized extracellular membrane vesicles with scanning ion occlusion sensing Nanomedicine (Lond) 8 2013 1443 1458
20. Y. Zhang, Z. Wang, and R.A. Gemeinhart Progress in microRNA delivery J. Control Release 172 2013 962 974
21. H. Lv, S. Zhang, B. Wang, S. Cui, and J. Yan Toxicity of cationic lipids and cationic polymers in gene delivery J. Control Release 114 2006 100 109 (Pubitemid 44128621)
22. A. Eguchi, and S.F. Dowdy SiRNA delivery using peptide transduction domains Trends Pharmacol. Sci. 30 2009 341 345
23. S. Ohno, M. Takanashi, K. Sudo, S. Ueda, A. Ishikawa, N. Matsuyama, K. Fujita, T. Mizutani, T. Ohgi, T. Ochiya, N. Gotoh, and M. Kuroda Systemically injected exosomes targeted to EGFR deliver antitumor microRNA to breast cancer cells Mol. Ther. 21 2013 185 191
24. N. Kosaka, H. Iguchi, Y. Yoshioka, K. Hagiwara, F. Takeshita, and T. Ochiya Competitive interactions of cancer cells and normal cells via secretory microRNAs J. Biol. Chem. 287 2012 1397 1405
25. J.D. Arroyo, J.R. Chevillet, E.M. Kroh, I.K. Ruf, C.C. Pritchard, D.F. Gibson, P.S. Mitchell, C.F. Bennett, E.L. Pogosova-Agadjanyan, D.L. Stirewalt, J.F. Tait, and M. Tewari Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma Proc. Natl. Acad. Sci. U.S.A. 108 2011 5003 5008
26. E. Spaeth, A. Klopp, J. Dembinski, M. Andreeff, and F. Marini Inflammation and tumor microenvironments: defining the migratory itinerary of mesenchymal stem cells Gene Ther. 15 2008 730 738 (Pubitemid 351627356)
27. T. Katsuda, N. Kosaka, F. Takeshita, and T. Ochiya The therapeutic potential of mesenchymal stem cell-derived extracellular vesicles Proteomics 13 2013 1637 1653
28. T.S. Chen, R.C. Lai, M.M. Lee, A.B. Choo, C.N. Lee, and S.K. Lim Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs Nucleic Acids Res. 38 2010 215 224
29. H.K. Lee, S. Finniss, S. Cazacu, E. Bucris, A. Ziv-Av, C. Xiang, K. Bobbitt, S.A. Rempel, L. Hasselbach, T. Mikkelsen, S. Slavin, and C. Brodie Mesenchymal stem cells deliver synthetic microRNA mimics to glioma cells and glioma stem cells and inhibit their cell migration and self-renewal Oncotarget 4 2013 346 361
30. W. Zhu, L. Huang, Y. Li, X. Zhang, J. Gu, Y. Yan, X. Xu, M. Wang, H. Qian, and W. Xu Exosomes derived from human bone marrow mesenchymal stem cells promote tumor growth in vivo Cancer Lett. 315 2012 28 37