Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting

Journal of Extracellular Vesicles

Volumn 4, Issue 2015, 2015, Pages 1-13

  Wiklander, Oscar P B ^a   Nordin, Joel Z ^a   O'Loughlin, Aisling ^b   Gustafsson, Ylva ^a   Corso, Giulia ^a   Mäger, Imre ^b,c   Vader, Pieter ^b   Lee, Yi ^b   Sork, Helena ^a   Seow, Yiqi ^d   Heldring, Nina ^a   Alvarez Erviti, Lydia ^e   Edvard Smith, C I ^a   Le Blanc, Katarina ^a,f   Macchiarini, Paolo ^a   Jungebluth, Philipp ^a,g   Wood, Matthew J A ^b   El Andaloussi, Samir ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF TARTU   (Estonia)

^d AGENCY FOR SCIENCE   (Singapore)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

^f KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^g UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Biodistribution; Drug delivery; Exosomes; Extracellular vesicles; Microvesicles; Nanotechnology; Tissue targeting

Indexed keywords

CHOLINERGIC RECEPTOR; LIPOSOME; NANOPARTICLE; SMALL INTERFERING RNA;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL COMMUNICATION; CELL FATE; CELL FRACTIONATION; CELL ISOLATION; CELL SIZE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DENDRITIC CELL; DRUG DELIVERY SYSTEM; ENDOCRINE SYSTEM; EXOSOME; FEMALE; GASTROINTESTINAL TRACT; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; LIVER; LUNG; MALE; MESENCHYMAL STEM CELL; MOUSE; NANOTECHNOLOGY; NEAR INFRARED SPECTROSCOPY; NONHUMAN; ORGAN PERFUSION; PANCREAS; PARACRINE SIGNALING; SPLEEN; TRANSMISSION ELECTRON MICROSCOPY; ULTRACENTRIFUGATION; WESTERN BLOTTING; XENOTRANSPLANTATION;

MUS; RABIES VIRUS;

EID: 85016490706     PISSN: None     EISSN: 20013078     Source Type: Journal    
DOI: 10.3402/jev.v4.26316     Document Type: Article

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