Microvesicle- and exosome-mediated drug delivery enhances the cytotoxicity of Paclitaxel in autologous prostate cancer cells

Journal of Controlled Release

Volumn 220, Issue , 2015, Pages 727-737

  Saari, Heikki ^a   Lázaro Ibáñez, Elisa ^a   Viitala, Tapani ^a   Vuorimaa Laukkanen, Elina ^b   Siljander, Pia ^a   Yliperttula, Marjo ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

Author keywords

Drug delivery; Exosomes; Extracellular vesicles; Microvesicles; Paclitaxel; Prostate cancer

Indexed keywords

CELL CULTURE; CONFOCAL MICROSCOPY; CYTOLOGY; CYTOTOXICITY; DISEASES; DRUG DELIVERY; MOLECULAR BIOLOGY; UROLOGY;

EXOSOMES; EXTRACELLULAR; MICROVESICLES; PACLITAXEL; PROSTATE CANCERS;

CELLS;

DRUG CARRIER; MEMBRANE PROTEIN; PACLITAXEL; ANTINEOPLASTIC AGENT; NANOPARTICLE;

ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL VIABILITY; CENTRIFUGATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; ELECTRON MICROSCOPY; ENDOCYTOSIS; EXOSOME; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MALE; MEMBRANE MICROPARTICLE; PRIORITY JOURNAL; PROSTATE CANCER; WESTERN BLOTTING; CELL SURVIVAL; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; MEDICINAL CHEMISTRY; METABOLISM; PATHOLOGY; PHENOTYPE; PROSTATIC NEOPLASMS; TIME FACTOR; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CELL SURVIVAL; CELL-DERIVED MICROPARTICLES; CHEMISTRY, PHARMACEUTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; ENDOCYTOSIS; EXOSOMES; HUMANS; MALE; NANOPARTICLES; PACLITAXEL; PHENOTYPE; PROSTATIC NEOPLASMS; TIME FACTORS;

EID: 84949564767     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.09.031     Document Type: Article

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