Molecular Structure of the Human CFTR Ion Channel

Cell

Volumn 169, Issue 1, 2017, Pages 85-95.e8

  Liu, Fangyu ^a   Zhang, Zhe ^a,b   Csanády, László ^c   Gadsby, David C ^a   Chen, Jue ^a,b  

^a ROCKEFELLER UNIVERSITY   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

ABC transporter; anion channel; cryo EM; human CFTR

Indexed keywords

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; ARGININE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYSTEINE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; LYSINE; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 1; NBD1 PROTEIN; PROLINE; PROTEIN; SERINE; UNCLASSIFIED DRUG; CFTR PROTEIN, HUMAN; CFTR PROTEIN, ZEBRAFISH; ZEBRAFISH PROTEIN;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; CYTOPLASM; DIMERIZATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEPHOSPHORYLATION; PROTEIN HYDROLYSIS; PROTEIN PHOSPHORYLATION; STEREOCHEMISTRY; VESTIBULE; ZEBRA FISH; ANIMAL; BOVINE; CHEMISTRY; HYDROLYSIS; METABOLISM; MOLECULAR MODEL; PROTEIN DOMAIN; XENOPUS LAEVIS;

ADENOSINE TRIPHOSPHATE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CATTLE; CRYOELECTRON MICROSCOPY; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HUMANS; HYDROLYSIS; MODELS, MOLECULAR; PROTEIN DOMAINS; XENOPUS LAEVIS; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 85016073190     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2017.02.024     Document Type: Article

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