The Alzheimer's disease risk factors apolipoprotein E and TREM2 are linked in a receptor signaling pathway

Journal of Neuroinflammation

Volumn 14, Issue 1, 2017, Pages

  Jendresen, Charlotte ^a   Årskog, Vibeke ^a   Daws, Michael R ^b   Nilsson, Lars N G ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

Alzheimer's disease; Apolipoprotein E (ApoE); Neuroinflammation; Reporter cells; Triggering receptor expressed on myeloid cells 2 (TREM2)

Indexed keywords

APOLIPOPROTEIN E; APOLIPOPROTEIN E2; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; BETA GALACTOSIDASE; CD8 ANTIGEN; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2; AMYLOID PRECURSOR PROTEIN; IMMUNOGLOBULIN RECEPTOR; ISOPROTEIN; MEMBRANE PROTEIN; PROTEIN BINDING; TREM2 PROTEIN, HUMAN;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; APOE GENE; ARTICLE; BINDING AFFINITY; CALCIUM CELL LEVEL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE; GENETIC RISK; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PATHOGENESIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; RISK FACTOR; SIGNAL TRANSDUCTION; TREM2 GENE; WESTERN BLOTTING; AGE; ANIMAL; BIOLOGICAL MODEL; BRAIN; GENETICS; METABOLISM; MOLECULAR MODEL; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN DOMAIN; PROTEIN MICROARRAY; T LYMPHOCYTE; TRANSFORMED CELL LINE; TRANSGENIC MOUSE;

AGE FACTORS; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; APOLIPOPROTEINS E; BRAIN; CELL LINE, TRANSFORMED; HUMANS; MEMBRANE GLYCOPROTEINS; MICE; MICE, TRANSGENIC; MODELS, BIOLOGICAL; MODELS, MOLECULAR; PROTEIN ARRAY ANALYSIS; PROTEIN BINDING; PROTEIN DOMAINS; PROTEIN ISOFORMS; RECEPTORS, IMMUNOLOGIC; RISK FACTORS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 85015758641     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-017-0835-4     Document Type: Article

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