Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis

Journal of Biological Chemistry

Volumn 272, Issue 29, 1997, Pages 17972-17980

  Sullivan, Patrick M ^a   Mezdour, Hafid ^a   Aratani, Yasuaki ^a,d   Knouff, Chris ^a   Najib, Jamila ^b   Reddick, Robert L ^a,e   Quarfordt, Steven H ^c   Maeda, Nobuyo ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b INSTITUT PASTEUR DE LILLE   (France)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d YOKOHAMA CITY UNIVERSITY   (Japan)

^e UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E;

ALLELE; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BINDING AFFINITY; CELL MIGRATION; CHOLESTEROL DIET; ENHANCER REGION; GENE REPLICATION; GENE TARGETING; GENETIC SUSCEPTIBILITY; HUMAN; HYPERCHOLESTEROLEMIA; LIPOPROTEIN METABOLISM; NONHUMAN; PRIORITY JOURNAL;

ALLELES; ANIMALS; APOLIPOPROTEIN E3; APOLIPOPROTEINS E; ARTERIOSCLEROSIS; CHOLESTEROL; CHOLESTEROL, HDL; DIET, ATHEROGENIC; FEMALE; HOMOZYGOTE; HUMANS; HYPERCHOLESTEROLEMIA; MALE; MICE; MICE, TRANSGENIC; RESTRICTION MAPPING; STEM CELLS; TRIGLYCERIDES;

ANIMALIA;

EID: 0030741533     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.29.17972     Document Type: Article

References (47)

1. Weisgraber, K. H. (1994) Adv. Protein Chem. 45, 249-302
2. Herz, J., Hamann, U., Rogne, S., Myklebost, O., Gausepohl, H., and Stanley, K. K. (1988) EMBO J. 7, 4119-4127
3. Mahley, R. W., and Innerarity, T. L. (1977) J. Biol. Chem. 252, 3980-3986
4. Mahley, R. W. (1978) in Disturbances in Lipid and Lipoprotein Metabolism (Dietschy, J. M., Gotto, A. M., Jr., and Ontko, J. A., eds) pp. 181-197, American Physiological Society, Bethesda
5. Olaisen, B., Teisberg, P., and Gedde-Dahl, T., Jr. (1932) Hum. Genet. 62, 233
6. Kardassis, D., Laccotripe, M., Talianidis, I., and Zannis, V. (1996) Hypertension 27, 980-1008
7. Paik, Y.-K., Chang, D. J., Reardon, C. A., Walker, M. D., Taxman, E., and Taylor, J. M. (1988) J. Biol. Chem. 263, 13340-13349
8. Smith, J. D., Melian, A., Leff, T., and Breslow, J. L. (1988) J. Biol. Chem. 263, 8300-8308
9. Simonet, W. S., Bucay, N., Lauer, S. J., and Taylor, J. M. (1993) J. Biol. Chem. 268, 8221-8229
10. Blue, M. L., Williams, D. L., Zucker, S., Khan, S. A., and Blum, C. B. (1983) Proc. Natl. Acad. Sci. U. S. A. 80, 283-287
11. Basu, S. K., Ho, Y. K., Brown, M. S., Bilheimer, D. W., Anderson, R. G. W., and Goldstein, J. L. (1982) J. Biol. Chem. 257, 9788-9795
12. Hallman, D. M., Boerwinkle, E., Saha, N., Sandholzer, C., Menzel, H. J., Csázár, A., and Utermann, G. (1991) Am. J. Hum. Genet. 49, 338-349
13. Rall, S. C., Jr., Weisgraber, K. H., and Mahley, R. W. (1982) J. Biol. Chem. 257, 4171-4178
14. Weisgraber, K. H., Innerarity, T. L., and Mahley, R. W. (1982) J. Biol. Chem. 257, 2518-2521
15. Utermann, G. (1982) La Ricerca Clin. Lab. 12, 23-33
16. Boerwinkle, E., Visvikis, S., Welsh, D., Steinmetz, J., Hanash, S. M., and Sing, C. P. (1987) Am. J. Hum. Genet. 27, 567-582
17. Schmechel, D. E., Saunders, A. M., Strittmatter, W. J., Crain, B. J., Hulette, C. M., Joo, S. H., Pericak-Vance, M. A., Goldgaber, D., and Roses, A. D. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 9649-9653
18. Saunders, A. M., Strittmatter, W. J., Schmechel, D., George-Hyslop, S. T., Pericak-Vance, M. A., Joo, S. H., Rosi, B. L., Gusella, J. F., Crapper-MacLachlan, D. R., Albert, M. J., Hulette, C., Crain, B., Goldgaber, D., and Roses, A. D. (1993) Neurology 43, 1467-1472
19. Smith, J. D., Plump, A. S., Hayek, T., Walsh, A., and Breslow, J. L. (1990) J. Biol. Chem. 265, 14709-14712
20. Simonet, W. S., Bucay, N., Lauer, S. J., Wirak, D. O., Stevens, M. E., Weisgraber, K. H., Pitas, R. E., and Taylor, J. M. (1990) J. Biol. Chem. 265, 10809-10812
21. Fazio, S., Horie, Y., Simonet, W. S., Weisgraber, K. H., Taylor, J. M., and Rall, S. C., Jr. (1994) J. Lipid Res. 35, 408-416
22. Mortimer, B.-C., Redgrave, T. G., Spangler, E. A., Verstuyft, J. G., and Rubin, E. M. (1994) Arterioscler. Thromb. 14, 1542-1552
23. van den Maagdenberg, A. M. J. M., Hofker, M. H., Krimpenfort, P. J. A., de Bruijn, I., van Vlijmen, B., van der Boom, H., Havekes, L. M., and Frants, R. R. (1993) J. Biol. Chem. 268, 10540-10545
24. Xu, P.-T., Schmechel, D., Rothrock-Christian, T., Burkhart, D. S., Qiu, H-L., Popko, B., Sullivan, P. M., Maeda, N., Saunders, A. M., Roses, A. D., and Gilbert, J. R. (1996) Neurobiol. Dis. 3, 229-245
25. Tybulewicz, V. L. J., Crawford, C. E., Jackson, P. K., Bronson, R. T., and Mulligan, R. C. (1991) Cell 65, 1153-1163
26. Koller, B. H., Kim, H.-S., Latour, A. M., Brigman, K., Boucher, R. C., Jr., Scrambler, P., Wainwright, B., and Smithies, O. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 10730-10734
27. de Silva, H. V., Más-Oliva, J., Taylor, J. M., and Mahley, R. W. (1994) J. Lipid Res. 35, 1297-1310
28. Chomczynski, P., and Sacchi, N. (1987) Anal. Biochem. 162, 156-159
29. Thomas, P. S. (1980) Proc. Natl. Acad. Sci. U. S. A. 77, 5201-5205
30. Leroy, A., Vu-dac, N., Koffigan, M., Clavey, V., and Fruchart, J. C. (1988) J. Immunoassay 9, 309-334
31. Quarfordt, S. H., Oswald, B., Xu, H. S., Zhang, S., and Maeda, N. (1995) J. Lipid Res. 36, 1227-1235
32. Zhang, S. H., Reddick, R. L., Burkey, B., and Maeda, N. (1994) J. Clin. Invest. 94, 937-945
33. Green, E. K., Bain, S. C., Day, P. J. R., Barnett, A. H., Charelson, F., Jones, A. F., and Walker, M. R. (1991) Clin. Chem. 37, 1263-1268
34. Robinson, S. F., and Quarfordt, S. H. (1978) Biochim. Biophys. Acta 541, 492-503
35. Imaizumi, K., Fainaru, M., and Havel, B. J. (1978) J. Lipid Res. 19, 712-722
36. de Silva, H. V., Lauer, S. J., Wang, J., Simonet, W. S., Weisgraber, K. H., Mahley, R. W., and Taylor, J. M. (1994) J. Biol. Chem. 269, 2324-2335
37. Yang, Y.-W., Chan, L., and Li, W.-H. (1991) J. Mol. Evol. 32, 469-475
38. Wardell, M. R., Brennan, S. O., James, E. D., Fraser, R., and Carrell, R. W. (1987) J. Clin. Invest. 80, 483-490
39. Lalazar, A., Weisgraber, K. H., Rall, S. C., Jr., Giladi, H., Innerarity, T. L., Levanon, A. Z., Boyles, J. K., Amit, B., Gorecki, M., Mahley, R. W., and Vogel, T. (1988) J. Biol. Chem. 263, 3542-3545
40. Landis, B. A., Rotolo, F. S., Meyers, W. C., Clark, A. B., and Quarfordt, S. H. (1987) Am. J. Physiol. 252, C805-C810
41. Mahley, R. W., and Hussain, M. M. (1991) Curr. Opin. Lipidol. 2, 170-176
42. Mahley, R. W., Weisgraber, K. H., and Innerarity, T. L. (1979) Biochim. Biophys. Acta 575, 81-91
43. Weisgraber, K. H. (1990) J. Lipid Res. 31, 1503-1511
44. Taylor, J. M., Simonet, W. S., Bucay, N., Lauer, S. J., and de Silva, H. V. (1991) Curr. Opin. Lipidol. 2, 73-80
45. Zilversmit, D. B. (1979) Circulation 60, 473-485
46. Slyper, A. H. (1992) Lancet 340, 289-291
47. van Vlijmen, B. J. M., van Dijk, K. W., van't Hof, H. B., van Gorp, P. J. J., van der Zee, A., van der Boom, H., Breuer, M. L., Hofker, M. H., and Havekes, L. M. (1996) J. Biol. Chem. 271, 30595-30602