Harnessing LRIG1-mediated inhibition of receptor tyrosine kinases for cancer therapy

Biochimica et Biophysica Acta - Reviews on Cancer

Volumn 1868, Issue 1, 2017, Pages 109-116

  Neirinckx, Virginie ^a   Hedman, Hakan ^b   Niclou, Simone P ^a,c  

^a LUXEMBOURG INSTITUTE OF HEALTH   (Luxembourg)

^b UMEÅ UNIVERSITY   (Sweden)

^c UNIVERSITY OF BERGEN   (Norway)

Author keywords

Cancer; Ectodomain; Leucine rich repeats and immunoglobulin like domains containing protein 1; Nervous system; Receptor tyrosine kinase

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; ESTROGEN RECEPTOR ALPHA; LRIG1 PROTEIN; LRIG2 PROTEIN; LRIG3 PROTEIN; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; UBIQUITIN; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; PROTEIN KINASE INHIBITOR;

CANCER THERAPY; CARCINOGENESIS; ENZYME INHIBITION; ENZYME REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION; LRIG1 GENE; MOLECULARLY TARGETED THERAPY; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW; SIGNAL TRANSDUCTION; STEM CELL; TUMOR GROWTH; TUMOR SUPPRESSOR GENE; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL PROLIFERATION; DRUG EFFECTS; HUMAN; METABOLISM; NEOPLASMS;

ANIMALS; CELL PROLIFERATION; HUMANS; MEMBRANE GLYCOPROTEINS; NEOPLASMS; PROTEIN KINASE INHIBITORS; RECEPTOR PROTEIN-TYROSINE KINASES;

EID: 85015092633     PISSN: 0304419X     EISSN: 18792561     Source Type: Journal    
DOI: 10.1016/j.bbcan.2017.02.007     Document Type: Review

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