-
1
-
-
67349237981
-
Ubiquitin in trafficking: The network at work
-
Acconcia F., Sigismund S, Polo S. 2009. Ubiquitin in trafficking: The network at work. Exp Cell Res 315: 1610-1618.
-
(2009)
Exp Cell Res
, vol.315
, pp. 1610-1618
-
-
Acconcia, F.1
Sigismund, S.2
Polo, S.3
-
2
-
-
64549154396
-
Diversity of polyubiquitin chains
-
Adhikari A., Chen ZJ. 2009. Diversity of polyubiquitin chains. Dev Cell 16: 485-486.
-
(2009)
Dev Cell
, vol.16
, pp. 485-486
-
-
Adhikari, A.1
Chen, Z.J.2
-
3
-
-
33646396185
-
Cell survival through Trk neurotrophin receptors is differentially regulated by ubiquitination
-
Arevalo J.C., Waite J, Rajagopal R, Beyna M, Chen ZY, Lee FS, Chao MV. 2006. Cell survival through Trk neurotrophin receptors is differentially regulated by ubiquitination. Neuron 50: 549-559.
-
(2006)
Neuron
, vol.50
, pp. 549-559
-
-
Arevalo, J.C.1
Waite, J.2
Rajagopal, R.3
Beyna, M.4
Chen, Z.Y.5
Lee, F.S.6
Chao, M.V.7
-
4
-
-
0038323973
-
STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes
-
Bache K.G., Raiborg C, Mehlum A, Stenmark H. 2003. STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes. J Biol Chem 278: 12513-12521.
-
(2003)
J Biol Chem
, vol.278
, pp. 12513-12521
-
-
Bache, K.G.1
Raiborg, C.2
Mehlum, A.3
Stenmark, H.4
-
5
-
-
0026343342
-
Insulin receptors internalize by a rapid, saturable pathway requiring receptor autophosphorylation and an intact juxtamembrane region
-
Backer J.M., Shoelson SE, Haring E, White MF. 1991. Insulin receptors internalize by a rapid, saturable pathway requiring receptor autophosphorylation and an intact juxtamembrane region. J Cell Biol 115: 1535-1545.
-
(1991)
J Cell Biol
, vol.115
, pp. 1535-1545
-
-
Backer, J.M.1
Shoelson, S.E.2
Haring, E.3
White, M.F.4
-
6
-
-
0026730995
-
The insulin receptor juxtamembrane region contains two independent tyrosine/ β-turn internalization signals
-
Backer J.M., Shoelson SE, Weiss MA, Hua QX, Cheatham RB, Haring E., Cahill DC, White MF. 1992. The insulin receptor juxtamembrane region contains two independent tyrosine/ β-turn internalization signals. J Cell Biol 118: 831-839.
-
(1992)
J Cell Biol
, vol.118
, pp. 831-839
-
-
Backer, J.M.1
Shoelson, S.E.2
Weiss, M.A.3
Hua, Q.X.4
Cheatham, R.B.5
Haring, E.6
Cahill, D.C.7
White, M.F.8
-
7
-
-
0034714277
-
Threonine phosphorylation diverts internalized epidermal growth factor receptors from a degradative pathway to the recycling endosome
-
Bao J., Alroy I, Waterman H, Schejter ED, Brodie C, Gruenberg J., Yarden Y. 2000. Threonine phosphorylation diverts internalized epidermal growth factor receptors from a degradative pathway to the recycling endosome. J Biol Chem 275: 26178-26186.
-
(2000)
J Biol Chem
, vol.275
, pp. 26178-26186
-
-
Bao, J.1
Alroy, I.2
Waterman, H.3
Schejter, E.D.4
Brodie, C.5
Gruenberg, J.6
Yarden, Y.7
-
8
-
-
0037418192
-
Src promotes destruction of c-Cbl: Implications for oncogenic synergy between Src and growth factor receptors
-
Bao J., Gur G, Yarden Y. 2003. Src promotes destruction of c-Cbl: Implications for oncogenic synergy between Src and growth factor receptors. Proc Natl Acad Sci 100: 2438-2443.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 2438-2443
-
-
Bao, J.1
Gur, G.2
Yarden, Y.3
-
9
-
-
0034735517
-
Epidermal growth factor and membrane trafficking. EGF receptor activation of endocytosis requires Rab5a
-
Barbieri M.A., Roberts RL, Gumusboga A, Highfield H, Alvarez-Dominguez C., Wells A, Stahl PD. 2000. Epidermal growth factor and membrane trafficking. EGF receptor activation of endocytosis requires Rab5a. J Cell Biol 151: 539-550.
-
(2000)
J Cell Biol
, vol.151
, pp. 539-550
-
-
Barbieri, M.A.1
Roberts, R.L.2
Gumusboga, A.3
Highfield, H.4
Alvarez-Dominguez, C.5
Wells, A.6
Stahl, P.D.7
-
10
-
-
0028040812
-
Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor
-
Batzer A.G., Rotin D, Urena JM, Skolnik EY, Schlessinger J. 1994. Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor. Mol Cell Biol 14: 5192-5201.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 5192-5201
-
-
Batzer, A.G.1
Rotin, D.2
Urena, J.M.3
Skolnik, E.Y.4
Schlessinger, J.5
-
11
-
-
0034307565
-
NGF signals through TrkA to increase clathrin at the plasma membrane and enhance clathrin-mediated membrane trafficking
-
Beattie E.C., Howe CL, Wilde A, Brodsky FM, Mobley WC. 2000. NGF signals through TrkA to increase clathrin at the plasma membrane and enhance clathrin-mediated membrane trafficking. J Neurosci 20: 7325-7333.
-
(2000)
J Neurosci
, vol.20
, pp. 7325-7333
-
-
Beattie, E.C.1
Howe, C.L.2
Wilde, A.3
Brodsky, F.M.4
Mobley, W.C.5
-
12
-
-
0041654309
-
Down-regulation of the epidermal growth factor receptor in KB cells is due to receptor internalization and subsequent degradation in lysosomes
-
Beguinot L., Lyall RM, Willingham MC, Pastan I. 1984. Down-regulation of the epidermal growth factor receptor in KB cells is due to receptor internalization and subsequent degradation in lysosomes. Proc Natl Acad Sci 81: 2384-2388.
-
(1984)
Proc Natl Acad Sci
, vol.81
, pp. 2384-2388
-
-
Beguinot, L.1
Lyall, R.M.2
Willingham, M.C.3
Pastan, I.4
-
13
-
-
67349256390
-
Hrs regulates the endocytic sorting of the fibroblast growth factor receptor 2b
-
Belleudi F., Leone L, Maggio M, Torrisi MR. 2009. Hrs regulates the endocytic sorting of the fibroblast growth factor receptor 2b. Exp Cell Res 315: 2181-2191.
-
(2009)
Exp Cell Res
, vol.315
, pp. 2181-2191
-
-
Belleudi, F.1
Leone, L.2
Maggio, M.3
Torrisi, M.R.4
-
14
-
-
70349258220
-
Oligomerized Tie2 localizes to clathrin-coated pits in response to angiopoietin-1
-
Bogdanovic E., Coombs N, Dumont DJ. 2009. Oligomerized Tie2 localizes to clathrin-coated pits in response to angiopoietin-1. Histochem Cell Biol 132: 225-237.
-
(2009)
Histochem Cell Biol
, vol.132
, pp. 225-237
-
-
Bogdanovic, E.1
Coombs, N.2
Dumont, D.J.3
-
15
-
-
0033776145
-
ERBIN: A basolateral PDZ protein that interacts with the mammalian ERBB2/HER2 receptor
-
Borg J.P., Marchetto S, Le Bivic A, Ollendorff V, Jaulin-Bastard F., Saito H, Fournier E, Adelaide J, Margolis B, Birnbaum D. 2000. ERBIN: A basolateral PDZ protein that interacts with the mammalian ERBB2/HER2 receptor. Nat Cell Biol 2: 407-414.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 407-414
-
-
Borg, J.P.1
Marchetto, S.2
Le Bivic, A.3
Ollendorff, V.4
Jaulin-Bastard, F.5
Saito, H.6
Fournier, E.7
Adelaide, J.8
Margolis, B.9
Birnbaum, D.10
-
16
-
-
33646171781
-
Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII
-
Bowers K., Piper SC, Edeling MA, Gray SR, Owen DJ, Lehner P.J., Luzio JP. 2006. Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII. J Biol Chem 281: 5094-5105.
-
(2006)
J Biol Chem
, vol.281
, pp. 5094-5105
-
-
Bowers, K.1
Piper, S.C.2
Edeling, M.A.3
Gray, S.R.4
Owen, D.J.5
Lehner, P.J.6
Luzio, J.P.7
-
17
-
-
80054025210
-
CIN85 interacting proteins in B cells-specific role for SHIP-1
-
M110.006239
-
Buchse T., Horras N, Lenfert E, Krystal G, Korbel S, Schumann M., Krause E, Mikkat S, Tiedge M. 2011. CIN85 interacting proteins in B cells-specific role for SHIP-1. Mol Cell Proteomics 10: M110.006239.
-
(2011)
Mol Cell Proteomics
, vol.10
-
-
Buchse, T.1
Horras, N.2
Lenfert, E.3
Krystal, G.4
Korbel, S.5
Schumann, M.6
Krause, E.7
Mikkat, S.8
Tiedge, M.9
-
18
-
-
0032789613
-
Human mammary epithelial cells rapidly exchange empty EGFR between surface and intracellular pools
-
Burke P.M., Wiley HS. 1999. Human mammary epithelial cells rapidly exchange empty EGFR between surface and intracellular pools. J Cell Physiol 180: 448-460.
-
(1999)
J Cell Physiol
, vol.180
, pp. 448-460
-
-
Burke, P.M.1
Wiley, H.S.2
-
19
-
-
33947245587
-
Neuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1
-
Cao Z., Wu X, Yen L, Sweeney C, Carraway KL 3rd. 2007. Neuregulin-induced ErbB3 downregulation is mediated by a protein stability cascade involving the E3 ubiquitin ligase Nrdp1. Mol Cell Biol 27: 2180-2188.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 2180-2188
-
-
Cao, Z.1
Wu, X.2
Yen, L.3
Sweeney, C.4
Carraway III, K.L.5
-
20
-
-
55949119629
-
Nedd4 controls animal growth by regulating IGF-1 signaling
-
Cao X.R., Lill NL, Boase N, Shi PP, Croucher DR, Shan H, Qu J., Sweezer EM, Place T, Kirby PA, et al. 2008. Nedd4 controls animal growth by regulating IGF-1 signaling. Sci Signal 1: ra5.
-
(2008)
Sci Signal
, vol.1
-
-
Cao, X.R.1
Lill, N.L.2
Boase, N.3
Shi, P.P.4
Croucher, D.R.5
Shan, H.6
Qu, J.7
Sweezer, E.M.8
Place, T.9
Kirby, P.A.10
-
21
-
-
0020335070
-
Co-localization of 125I-epidermal growth factor and ferritin-low density lipoprotein in coated pits: A quantitative electron microscopic study in normal and mutant human fibroblasts
-
Carpentier J.L., Gorden P, Anderson RG, Goldstein JL, Brown M.S., Cohen S, Orci L. 1982. Co-localization of 125I-epidermal growth factor and ferritin-low density lipoprotein in coated pits: A quantitative electron microscopic study in normal and mutant human fibroblasts. J Cell Biol 95: 73-77.
-
(1982)
J Cell Biol
, vol.95
, pp. 73-77
-
-
Carpentier, J.L.1
Gorden, P.2
Anderson, R.G.3
Goldstein, J.L.4
Brown, M.S.5
Cohen, S.6
Orci, L.7
-
22
-
-
0025250145
-
NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor
-
Chen W.J., Goldstein JL, Brown MS. 1990. NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor. J Biol Chem 265: 3116-3123.
-
(1990)
J Biol Chem
, vol.265
, pp. 3116-3123
-
-
Chen, W.J.1
Goldstein, J.L.2
Brown, M.S.3
-
23
-
-
69549086892
-
Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice
-
Chen H., Ko G, Zatti A, Di Giacomo G, Liu L, Raiteri E, Perucco E., Collesi C, Min W, Zeiss C, et al. 2009. Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice. Proc Natl Acad Sci 106: 13838-13843.
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 13838-13843
-
-
Chen, H.1
Ko, G.2
Zatti, A.3
Di Giacomo, G.4
Liu, L.5
Raiteri, E.6
Perucco, E.7
Collesi, C.8
Min, W.9
Zeiss, C.10
-
24
-
-
20244369288
-
Vav family GEFs link activated Ephs to endocytosis and axon guidance
-
Cowan C.W., Shao YR, Sahin M, Shamah SM, Lin MZ, Greer P.L., Gao S, Griffith EC, Brugge JS, Greenberg ME. 2005. Vav family GEFs link activated Ephs to endocytosis and axon guidance. Neuron 46: 205-217.
-
(2005)
Neuron
, vol.46
, pp. 205-217
-
-
Cowan, C.W.1
Shao, Y.R.2
Sahin, M.3
Shamah, S.M.4
Lin, M.Z.5
Greer, P.L.6
Gao, S.7
Griffith, E.C.8
Brugge, J.S.9
Greenberg, M.E.10
-
25
-
-
50449085442
-
The Rab5 guanylate exchange factor Rin1 regulates endocytosis of the EphA4 receptor in mature excitatory neurons
-
Deininger K., Eder M, Kramer ER, Zieglgansberger W, Dodt H.U., Dornmair K, Colicelli J, Klein R. 2008. The Rab5 guanylate exchange factor Rin1 regulates endocytosis of the EphA4 receptor in mature excitatory neurons. Proc Natl Acad Sci 105: 12539-12544.
-
(2008)
Proc Natl Acad Sci
, vol.105
, pp. 12539-12544
-
-
Deininger, K.1
Eder, M.2
Kramer, E.R.3
Zieglgansberger, W.4
Dodt, H.U.5
Dornmair, K.6
Colicelli, J.7
Klein, R.8
-
26
-
-
0034949705
-
c-Cbl ubiquitinates the EGF receptor at the plasma membrane and remains receptor associated throughout the endocytic route
-
de Melker AA, van der Horst G, Calafat J, Jansen H, Borst J. 2001. c-Cbl ubiquitinates the EGF receptor at the plasma membrane and remains receptor associated throughout the endocytic route. J Cell Sci 114: 2167-2178.
-
(2001)
J Cell Sci
, vol.114
, pp. 2167-2178
-
-
de Melker, A.A.1
van der Horst, G.2
Calafat, J.3
Jansen, H.4
Borst, J.5
-
27
-
-
34547764975
-
Malfunctions within the Cbl interactome uncouple receptor tyrosine kinases from destructive transport
-
Dikic I., Schmidt MH. 2007. Malfunctions within the Cbl interactome uncouple receptor tyrosine kinases from destructive transport. Eur J Cell Biol 86: 505-512.
-
(2007)
Eur J Cell Biol
, vol.86
, pp. 505-512
-
-
Dikic, I.1
Schmidt, M.H.2
-
28
-
-
0038165451
-
Vascular endothelial growth factor-dependent down-regulation of Flk-1/KDR involves Cbl-mediated ubiquitination. Consequences on nitric oxide production from endothelial cells
-
Duval M., Bedard-Goulet S, Delisle C, Gratton JP. 2003. Vascular endothelial growth factor-dependent down-regulation of Flk-1/KDR involves Cbl-mediated ubiquitination. Consequences on nitric oxide production from endothelial cells. J Biol Chem 278: 20091-20097.
-
(2003)
J Biol Chem
, vol.278
, pp. 20091-20097
-
-
Duval, M.1
Bedard-Goulet, S.2
Delisle, C.3
Gratton, J.P.4
-
29
-
-
77649274212
-
Membrane contacts between endosomes and ER provide sites for PTP1B-epidermal growth factor receptor interaction
-
Eden E.R., White IJ, Tsapara A, Futter CE. 2010. Membrane contacts between endosomes and ER provide sites for PTP1B-epidermal growth factor receptor interaction. Nat Cell Biol 12: 267-272.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 267-272
-
-
Eden, E.R.1
White, I.J.2
Tsapara, A.3
Futter, C.E.4
-
30
-
-
84855979997
-
The role of EGF receptor ubiquitination in regulating its intracellular traffic
-
Eden E.R., Huang F, Sorkin A, Futter CE. 2011. The role of EGF receptor ubiquitination in regulating its intracellular traffic. Traffic 13: 329-337.
-
(2011)
Traffic
, vol.13
, pp. 329-337
-
-
Eden, E.R.1
Huang, F.2
Sorkin, A.3
Futter, C.E.4
-
31
-
-
33746936677
-
Intrinsic tyrosine kinase activity is required for vascular endothelial growth factor receptor 2 ubiquitination, sorting and degradation in endothelial cells
-
Ewan L.C., Jopling HM, Jia H, Mittar S, Bagherzadeh A, Howell G.J., Walker JH, Zachary IC, Ponnambalam S. 2006. Intrinsic tyrosine kinase activity is required for vascular endothelial growth factor receptor 2 ubiquitination, sorting and degradation in endothelial cells. Traffic 7: 1270-1282.
-
(2006)
Traffic
, vol.7
, pp. 1270-1282
-
-
Ewan, L.C.1
Jopling, H.M.2
Jia, H.3
Mittar, S.4
Bagherzadeh, A.5
Howell, G.J.6
Walker, J.H.7
Zachary, I.C.8
Ponnambalam, S.9
-
32
-
-
38149016260
-
Ligand binding induces Cbl-dependent EphB1 receptor degradation through the lysosomal pathway
-
Fasen K., Cerretti DP, Huynh-Do U. 2008. Ligand binding induces Cbl-dependent EphB1 receptor degradation through the lysosomal pathway. Traffic 9: 251-266.
-
(2008)
Traffic
, vol.9
, pp. 251-266
-
-
Fasen, K.1
Cerretti, D.P.2
Huynh-Do, U.3
-
34
-
-
0028224965
-
Postendocytic trafficking of epidermal growth factor-receptor complexes is mediated through saturable and specific endosomal interactions
-
French A.R., Sudlow GP, Wiley HS, Lauffenburger DA. 1994. Postendocytic trafficking of epidermal growth factor-receptor complexes is mediated through saturable and specific endosomal interactions. J Biol Chem 269: 15749-15755.
-
(1994)
J Biol Chem
, vol.269
, pp. 15749-15755
-
-
French, A.R.1
Sudlow, G.P.2
Wiley, H.S.3
Lauffenburger, D.A.4
-
35
-
-
0028969961
-
Intracellular trafficking of epidermal growth factor family ligands is directly influenced by the pH sensitivity of the receptor/ligand interaction
-
French A.R., Tadaki DK, Niyogi SK, Lauffenburger DA. 1995. Intracellular trafficking of epidermal growth factor family ligands is directly influenced by the pH sensitivity of the receptor/ligand interaction. J Biol Chem 270: 4334-4340.
-
(1995)
J Biol Chem
, vol.270
, pp. 4334-4340
-
-
French, A.R.1
Tadaki, D.K.2
Niyogi, S.K.3
Lauffenburger, D.A.4
-
36
-
-
77951785332
-
A twotiered mechanism of EGFR inhibition by RALT/MIG6 via kinase suppression and receptor degradation
-
Frosi Y., Anastasi S, Ballaro C, Varsano G, Castellani L, Maspero E., Polo S, Alema S, Segatto O. 2010. A twotiered mechanism of EGFR inhibition by RALT/MIG6 via kinase suppression and receptor degradation. J Cell Biol 189: 557-571.
-
(2010)
J Cell Biol
, vol.189
, pp. 557-571
-
-
Frosi, Y.1
Anastasi, S.2
Ballaro, C.3
Varsano, G.4
Castellani, L.5
Maspero, E.6
Polo, S.7
Alema, S.8
Segatto, O.9
-
37
-
-
0029557613
-
The epidermal growth factor receptor is covalently linked to ubiquitin
-
Galcheva-Gargova Z, Theroux SJ, Davis RJ. 1995. The epidermal growth factor receptor is covalently linked to ubiquitin. Oncogene 11: 2649-2655.
-
(1995)
Oncogene
, vol.11
, pp. 2649-2655
-
-
Galcheva-Gargova, Z.1
Theroux, S.J.2
Davis, R.J.3
-
38
-
-
26944484011
-
Lysine 63 polyubiquitination of the nerve growth factor receptor TrkA directs internalization and signaling
-
Geetha T., Jiang J, Wooten MW. 2005. Lysine 63 polyubiquitination of the nerve growth factor receptor TrkA directs internalization and signaling. Mol Cell 20: 301-312.
-
(2005)
Mol Cell
, vol.20
, pp. 301-312
-
-
Geetha, T.1
Jiang, J.2
Wooten, M.W.3
-
39
-
-
21644463635
-
β-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase
-
Girnita L., Shenoy SK, Sehat B, Vasilcanu R, Girnita A, Lefkowitz R.J., Larsson O. 2005. β-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase. J Biol Chem 280: 24412-24419.
-
(2005)
J Biol Chem
, vol.280
, pp. 24412-24419
-
-
Girnita, L.1
Shenoy, S.K.2
Sehat, B.3
Vasilcanu, R.4
Girnita, A.5
Lefkowitz, R.J.6
Larsson, O.7
-
40
-
-
77953167957
-
Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor
-
Goh L.K., Huang F, Kim W, Gygi S, Sorkin A. 2010. Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor. J Cell Biol 189: 871-883.
-
(2010)
J Cell Biol
, vol.189
, pp. 871-883
-
-
Goh, L.K.1
Huang, F.2
Kim, W.3
Gygi, S.4
Sorkin, A.5
-
41
-
-
0018166797
-
Epidermal growth factor:Morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts
-
Gorden P., Carpentier JL, Cohen S, Orci L. 1978. Epidermal growth factor:Morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts. Proc Natl Acad Sci 75: 5025-5029.
-
(1978)
Proc Natl Acad Sci
, vol.75
, pp. 5025-5029
-
-
Gorden, P.1
Carpentier, J.L.2
Cohen, S.3
Orci, L.4
-
42
-
-
69249106881
-
Pathways and mechanisms of endocytic recycling
-
Grant B.D., Donaldson JG. 2009. Pathways and mechanisms of endocytic recycling. Nat Rev Mol Cell Biol 10: 597-608.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 597-608
-
-
Grant, B.D.1
Donaldson, J.G.2
-
43
-
-
20844462896
-
LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation
-
Gur G., Rubin C, Katz M, Amit I, Citri A, Nilsson J, Amariglio N., Henriksson R, Rechavi G, Hedman H, et al. 2004. LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation. EMBO J 23: 3270-3281.
-
(2004)
EMBO J
, vol.23
, pp. 3270-3281
-
-
Gur, G.1
Rubin, C.2
Katz, M.3
Amit, I.4
Citri, A.5
Nilsson, J.6
Amariglio, N.7
Henriksson, R.8
Rechavi, G.9
Hedman, H.10
-
44
-
-
0028079974
-
Involvement of dileucine motifs in the internalization and degradation of the insulin receptor
-
Haft C.R., Klausner RD, Taylor SI. 1994. Involvement of dileucine motifs in the internalization and degradation of the insulin receptor. J Biol Chem 269: 26286-26294.
-
(1994)
J Biol Chem
, vol.269
, pp. 26286-26294
-
-
Haft, C.R.1
Klausner, R.D.2
Taylor, S.I.3
-
45
-
-
0018581544
-
Rapid stimulation of pinocytosis in human carcinoma cells A-431 by epidermal growth factor
-
Haigler H.T., McKanna JA, Cohen S. 1979. Rapid stimulation of pinocytosis in human carcinoma cells A-431 by epidermal growth factor. J Cell Biol 83: 82-90.
-
(1979)
J Cell Biol
, vol.83
, pp. 82-90
-
-
Haigler, H.T.1
McKanna, J.A.2
Cohen, S.3
-
46
-
-
0030869073
-
Dual role of a dileucine motif in insulin receptor endocytosis
-
Hamer I., Haft CR, Paccaud JP, Maeder C, Taylor S, Carpentier JL. 1997. Dual role of a dileucine motif in insulin receptor endocytosis. J Biol Chem 272: 21685-21691.
-
(1997)
J Biol Chem
, vol.272
, pp. 21685-21691
-
-
Hamer, I.1
Haft, C.R.2
Paccaud, J.P.3
Maeder, C.4
Taylor, S.5
Carpentier, J.L.6
-
47
-
-
78751627951
-
Leucine-rich repeat kinase LRRK1 regulates endosomal trafficking of the EGF receptor
-
Hanafusa H., Ishikawa K, Kedashiro S, Saigo T, Iemura S, Natsume T., Komada M, Shibuya H, Nara A, Matsumoto K. 2011. Leucine-rich repeat kinase LRRK1 regulates endosomal trafficking of the EGF receptor. Nat Commun 2: 158.
-
(2011)
Nat Commun
, vol.2
, pp. 158
-
-
Hanafusa, H.1
Ishikawa, K.2
Kedashiro, S.3
Saigo, T.4
Iemura, S.5
Natsume, T.6
Komada, M.7
Shibuya, H.8
Nara, A.9
Matsumoto, K.10
-
48
-
-
34047274090
-
A novel sorting sequence in the b2-adrenergic receptor switches recycling from default to the Hrs-dependent mechanism
-
Hanyaloglu A.C., von Zastrow M. 2007. A novel sorting sequence in the b2-adrenergic receptor switches recycling from default to the Hrs-dependent mechanism. J Biol Chem 282: 3095-3104.
-
(2007)
J Biol Chem
, vol.282
, pp. 3095-3104
-
-
Hanyaloglu, A.C.1
von Zastrow, M.2
-
49
-
-
54249152045
-
Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis
-
Haugsten E.M., Malecki J, Bjorklund SM, Olsnes S, Wesche J. 2008. Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis. Mol Biol Cell 19: 3390-3403.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 3390-3403
-
-
Haugsten, E.M.1
Malecki, J.2
Bjorklund, S.M.3
Olsnes, S.4
Wesche, J.5
-
50
-
-
79960349078
-
Clathrin-and dynamin-independent endocytosis of FGFR3-Implications for signalling
-
Haugsten E.M., Zakrzewska M, Brech A, Pust S, Olsnes S, Sandvig K., Wesche J. 2011. Clathrin-and dynamin-independent endocytosis of FGFR3-Implications for signalling. PloS ONE 6: e21708.
-
(2011)
PloS ONE
, vol.6
-
-
Haugsten, E.M.1
Zakrzewska, M.2
Brech, A.3
Pust, S.4
Olsnes, S.5
Sandvig, K.6
Wesche, J.7
-
51
-
-
33644502037
-
Epsin 1 is a polyubiquitin-selective clathrin-associated sorting protein
-
Hawryluk M.J., Keyel PA, Mishra SK, Watkins SC, Heuser JE, Traub LM. 2006. Epsin 1 is a polyubiquitin-selective clathrin-associated sorting protein. Traffic 7: 262-281.
-
(2006)
Traffic
, vol.7
, pp. 262-281
-
-
Hawryluk, M.J.1
Keyel, P.A.2
Mishra, S.K.3
Watkins, S.C.4
Heuser, J.E.5
Traub, L.M.6
-
52
-
-
67449116833
-
Activation of protein kinase C a is necessary for sorting the PDGF β-receptor to Rab4a-dependent recycling
-
Hellberg C., Schmees C, Karlsson S, Ahgren A, Heldin CH. 2009. Activation of protein kinase C a is necessary for sorting the PDGF β-receptor to Rab4a-dependent recycling. Mol Biol Cell 20: 2856-2863.
-
(2009)
Mol Biol Cell
, vol.20
, pp. 2856-2863
-
-
Hellberg, C.1
Schmees, C.2
Karlsson, S.3
Ahgren, A.4
Heldin, C.H.5
-
54
-
-
1642422374
-
Association with membrane protrusions makes ErbB2 an internalization-resistant receptor
-
Hommelgaard A.M., Lerdrup M, van Deurs B. 2004. Association with membrane protrusions makes ErbB2 an internalization-resistant receptor. Mol Biol Cell 15: 1557-1567.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 1557-1567
-
-
Hommelgaard, A.M.1
Lerdrup, M.2
van Deurs, B.3
-
55
-
-
0025281993
-
Movement of internalized ligand-receptor complexes along a continuous endosomal reticulum
-
Hopkins C.R., Gibson A, Shipman M, Miller K. 1990. Movement of internalized ligand-receptor complexes along a continuous endosomal reticulum. Nature 346: 335-339.
-
(1990)
Nature
, vol.346
, pp. 335-339
-
-
Hopkins, C.R.1
Gibson, A.2
Shipman, M.3
Miller, K.4
-
56
-
-
14844334946
-
Grb2-mediated recruitment of the Cbl RING domain to the EGF receptor is essential and sufficient to support receptor endocytosis
-
Huang F., Sorkin A. 2005. Grb2-mediated recruitment of the Cbl RING domain to the EGF receptor is essential and sufficient to support receptor endocytosis. Mol Biol Cell 16: 1268-1281.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 1268-1281
-
-
Huang, F.1
Sorkin, A.2
-
57
-
-
78650658024
-
Structural basis for the interaction between the growth factor-binding protein GRB10 and the E3 ubiquitin ligase NEDD4
-
Huang Q., Szebenyi DM. 2010. Structural basis for the interaction between the growth factor-binding protein GRB10 and the E3 ubiquitin ligase NEDD4. J Biol Chem 285: 42130-42139.
-
(2010)
J Biol Chem
, vol.285
, pp. 42130-42139
-
-
Huang, Q.1
Szebenyi, D.M.2
-
58
-
-
0242290315
-
Tyrosine phosphorylation of the b2 subunit of clathrin adaptor complex AP-2 reveals the role of a di-leucine motif in the epidermal growth factor receptor trafficking
-
Huang F., Jiang X, Sorkin A. 2003. Tyrosine phosphorylation of the b2 subunit of clathrin adaptor complex AP-2 reveals the role of a di-leucine motif in the epidermal growth factor receptor trafficking. J Biol Chem 278: 43411-43417.
-
(2003)
J Biol Chem
, vol.278
, pp. 43411-43417
-
-
Huang, F.1
Jiang, X.2
Sorkin, A.3
-
59
-
-
1942469322
-
Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference
-
Huang F., Khvorova A, Marshall W, Sorkin A. 2004. Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference. J Biol Chem 279: 16657-16661.
-
(2004)
J Biol Chem
, vol.279
, pp. 16657-16661
-
-
Huang, F.1
Khvorova, A.2
Marshall, W.3
Sorkin, A.4
-
60
-
-
33644852909
-
Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain
-
Huang F., Kirkpatrick D, Jiang X, Gygi S, Sorkin A. 2006. Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain. Mol Cell 21: 737-748.
-
(2006)
Mol Cell
, vol.21
, pp. 737-748
-
-
Huang, F.1
Kirkpatrick, D.2
Jiang, X.3
Gygi, S.4
Sorkin, A.5
-
61
-
-
0023035529
-
Recycling of photoaffinity-labeled insulin receptors in rat adipocytes. Dissociation of insulin-receptor complexes is not required for receptor recycling
-
Huecksteadt T., Olefsky JM, Brandenberg D, Heidenreich KA. 1986. Recycling of photoaffinity-labeled insulin receptors in rat adipocytes. Dissociation of insulin-receptor complexes is not required for receptor recycling. J Biol Chem 261: 8655-8659.
-
(1986)
J Biol Chem
, vol.261
, pp. 8655-8659
-
-
Huecksteadt, T.1
Olefsky, J.M.2
Brandenberg, D.3
Heidenreich, K.A.4
-
62
-
-
0347093486
-
Hrs mediates downregulation of multiple signalling receptors in Drosophila
-
Jekely G., Rorth P. 2003. Hrs mediates downregulation of multiple signalling receptors in Drosophila. EMBO Rep 4: 1163-1168.
-
(2003)
EMBO Rep
, vol.4
, pp. 1163-1168
-
-
Jekely, G.1
Rorth, P.2
-
63
-
-
0042202634
-
Epidermal growth factor receptor internalization through clathrin-coated pits requires Cbl RING finger and proline-rich domains but not receptor polyubiquitylation
-
Jiang X., Sorkin A. 2003. Epidermal growth factor receptor internalization through clathrin-coated pits requires Cbl RING finger and proline-rich domains but not receptor polyubiquitylation. Traffic 4: 529-543.
-
(2003)
Traffic
, vol.4
, pp. 529-543
-
-
Jiang, X.1
Sorkin, A.2
-
64
-
-
0037339887
-
Grb2 regulates internalization of EGF receptors through clathrin-coated pits
-
Jiang X., Huang F, Marusyk A, Sorkin A. 2003. Grb2 regulates internalization of EGF receptors through clathrin-coated pits. Mol Biol Cell 14: 858-870.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 858-870
-
-
Jiang, X.1
Huang, F.2
Marusyk, A.3
Sorkin, A.4
-
65
-
-
30644476941
-
Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor-and Grb2-containing clathrin-coated pits
-
Johannessen L.E., Pedersen NM, Pedersen KW, Madshus IH, Stang E. 2006. Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor-and Grb2-containing clathrin-coated pits. Mol Cell Biol 26: 389-401.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 389-401
-
-
Johannessen, L.E.1
Pedersen, N.M.2
Pedersen, K.W.3
Madshus, I.H.4
Stang, E.5
-
66
-
-
79959720612
-
The VEGFR2 receptor tyrosine kinase undergoes constitutive endosome-to-plasma membrane recycling
-
Jopling H.M., Howell GJ, Gamper N, Ponnambalam S. 2011. The VEGFR2 receptor tyrosine kinase undergoes constitutive endosome-to-plasma membrane recycling. Biochem Biophys Res Commun 410: 170-176.
-
(2011)
Biochem Biophys Res Commun
, vol.410
, pp. 170-176
-
-
Jopling, H.M.1
Howell, G.J.2
Gamper, N.3
Ponnambalam, S.4
-
67
-
-
68949156319
-
Cell migration is regulated by platelet-derived growth factor receptor endocytosis
-
Kawada K., Upadhyay G, Ferandon S, Janarthanan S, Hall M, Vilardaga J.P., Yajnik V. 2009. Cell migration is regulated by platelet-derived growth factor receptor endocytosis. Mol Cell Biol 29: 4508-4518.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 4508-4518
-
-
Kawada, K.1
Upadhyay, G.2
Ferandon, S.3
Janarthanan, S.4
Hall, M.5
Vilardaga, J.P.6
Yajnik, V.7
-
68
-
-
58549096725
-
Epsin 1 is involved in recruitment of ubiquitinated EGF receptors into clathrin-coated pits
-
Kazazic M., Bertelsen V, Pedersen KW, Vuong TT, Grandal MV, Rodland MS, Traub LM, Stang E, Madshus IH. 2009. Epsin 1 is involved in recruitment of ubiquitinated EGF receptors into clathrin-coated pits. Traffic 10: 235-245.
-
(2009)
Traffic
, vol.10
, pp. 235-245
-
-
Kazazic, M.1
Bertelsen, V.2
Pedersen, K.W.3
Vuong, T.T.4
Grandal, M.V.5
Rodland, M.S.6
Traub, L.M.7
Stang, E.8
Madshus, I.H.9
-
69
-
-
57749196168
-
A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex
-
Kelly B.T., McCoy AJ, Spate K, Miller SE, Evans PR, Honing S, Owen DJ. 2008. A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex. Nature 456: 976-979.
-
(2008)
Nature
, vol.456
, pp. 976-979
-
-
Kelly, B.T.1
McCoy, A.J.2
Spate, K.3
Miller, S.E.4
Evans, P.R.5
Honing, S.6
Owen, D.J.7
-
70
-
-
0141994813
-
Identification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors
-
Kowanetz K., Szymkiewicz I, Haglund K, Kowanetz M, Husnjak K., Taylor JD, Soubeyran P, Engstrom U, Ladbury J.E., Dikic I. 2003. Identification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors. J Biol Chem 278: 39735-39746.
-
(2003)
J Biol Chem
, vol.278
, pp. 39735-39746
-
-
Kowanetz, K.1
Szymkiewicz, I.2
Haglund, K.3
Kowanetz, M.4
Husnjak, K.5
Taylor, J.D.6
Soubeyran, P.7
Engstrom, U.8
Ladbury, J.E.9
Dikic, I.10
-
71
-
-
33747165872
-
Vascular endothelial cadherin controls VEGFR-2 internalization and signaling fromintracellular compartments
-
Lampugnani M.G., Orsenigo F, Gagliani MC, Tacchetti C, Dejana E. 2006. Vascular endothelial cadherin controls VEGFR-2 internalization and signaling fromintracellular compartments. J Cell Biol 174: 593-604.
-
(2006)
J Cell Biol
, vol.174
, pp. 593-604
-
-
Lampugnani, M.G.1
Orsenigo, F.2
Gagliani, M.C.3
Tacchetti, C.4
Dejana, E.5
-
72
-
-
77952952373
-
VEGF receptor 2 endocytic trafficking regulates arterial morphogenesis
-
Lanahan A.A., Hermans K, Claes F, Kerley-Hamilton JS, Zhuang Z.W., Giordano FJ, Carmeliet P, Simons M. 2010. VEGF receptor 2 endocytic trafficking regulates arterial morphogenesis. Dev Cell 18: 713-724.
-
(2010)
Dev Cell
, vol.18
, pp. 713-724
-
-
Lanahan, A.A.1
Hermans, K.2
Claes, F.3
Kerley-Hamilton, J.S.4
Zhuang, Z.W.5
Giordano, F.J.6
Carmeliet, P.7
Simons, M.8
-
74
-
-
0033169024
-
The Cbl protooncoprotein stimulates CSF-1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation
-
Lee P.S., Wang Y, Dominguez MG, Yeung YG, Murphy MA, Bowtell DD, Stanley ER. 1999. The Cbl protooncoprotein stimulates CSF-1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation. EMBO J 18: 3616-3628.
-
(1999)
EMBO J
, vol.18
, pp. 3616-3628
-
-
Lee, P.S.1
Wang, Y.2
Dominguez, M.G.3
Yeung, Y.G.4
Murphy, M.A.5
Bowtell, D.D.6
Stanley, E.R.7
-
75
-
-
0033392493
-
Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1
-
Levkowitz G., Waterman H, Ettenberg SA, Katz M, Tsygankov AY, Alroy I, Lavi S, Iwai K, Reiss Y, Ciechanover A, et al. 1999. Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1. Mol Cell 4: 1029-1040.
-
(1999)
Mol Cell
, vol.4
, pp. 1029-1040
-
-
Levkowitz, G.1
Waterman, H.2
Ettenberg, S.A.3
Katz, M.4
Tsygankov, A.Y.5
Alroy, I.6
Lavi, S.7
Iwai, K.8
Reiss, Y.9
Ciechanover, A.10
-
76
-
-
34447126344
-
Specific Grb2-mediated interactions regulate clathrin-dependent endocytosis of the cMet-tyrosine kinase
-
Li N., Lorinczi M, Ireton K, Elferink LA. 2007. Specific Grb2-mediated interactions regulate clathrin-dependent endocytosis of the cMet-tyrosine kinase. J Biol Chem 282: 16764-16775.
-
(2007)
J Biol Chem
, vol.282
, pp. 16764-16775
-
-
Li, N.1
Lorinczi, M.2
Ireton, K.3
Elferink, L.A.4
-
77
-
-
69249218913
-
WW domain containing E3 ubiquitin protein ligase 1 targets the fulllength ErbB4 for ubiquitin-mediated degradation in breast cancer
-
Li Y., Zhou Z, Alimandi M, Chen C. 2009. WW domain containing E3 ubiquitin protein ligase 1 targets the fulllength ErbB4 for ubiquitin-mediated degradation in breast cancer. Oncogene 28: 2948-2958.
-
(2009)
Oncogene
, vol.28
, pp. 2948-2958
-
-
Li, Y.1
Zhou, Z.2
Alimandi, M.3
Chen, C.4
-
78
-
-
70450225242
-
Participation of Tom1L1 in EGF-stimulated endocytosis of EGF receptor
-
Liu N.S., Loo LS, Loh E, Seet LF, Hong W. 2009. Participation of Tom1L1 in EGF-stimulated endocytosis of EGF receptor. EMBO J 28: 3485-3499.
-
(2009)
EMBO J
, vol.28
, pp. 3485-3499
-
-
Liu, N.S.1
Loo, L.S.2
Loh, E.3
Seet, L.F.4
Hong, W.5
-
79
-
-
34248171369
-
Targeting of AMSH to endosomes is required for epidermal growth factor receptor degradation
-
Ma Y.M., Boucrot E, Villen J, Affar el B, Gygi SP, Gottlinger HG, Kirchhausen T. 2007. Targeting of AMSH to endosomes is required for epidermal growth factor receptor degradation. J Biol Chem 282: 9805-9812.
-
(2007)
J Biol Chem
, vol.282
, pp. 9805-9812
-
-
Ma, Y.M.1
Boucrot, E.2
Villen, J.3
Affar el, B.4
Gygi, S.P.5
Gottlinger, H.G.6
Kirchhausen, T.7
-
80
-
-
82355171859
-
Poly-ubiquitination of the insulin-like growth factor I receptor (IGF-IR) activation loop promotes antibody-induced receptor internalization and down-regulation
-
Mao Y., Shang Y, Pham VC, Ernst JA, Lill JR, Scales SJ, Zha J. 2011. Poly-ubiquitination of the insulin-like growth factor I receptor (IGF-IR) activation loop promotes antibody-induced receptor internalization and down-regulation. J Biol Chem 286: 41852-41861.
-
(2011)
J Biol Chem
, vol.286
, pp. 41852-41861
-
-
Mao, Y.1
Shang, Y.2
Pham, V.C.3
Ernst, J.A.4
Lill, J.R.5
Scales, S.J.6
Zha, J.7
-
81
-
-
1842591231
-
Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases
-
Marmor MD, Yarden Y. 2004. Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases. Oncogene 23: 2057-2070.
-
(2004)
Oncogene
, vol.23
, pp. 2057-2070
-
-
Marmor, M.D.1
Yarden, Y.2
-
82
-
-
0027472437
-
Consumption of EGF by A431 cells: Evidence for receptor recycling
-
Masui H., Castro L, Mendelsohn J. 1993. Consumption of EGF by A431 cells: Evidence for receptor recycling. J Cell Biol 120: 85-93.
-
(1993)
J Cell Biol
, vol.120
, pp. 85-93
-
-
Masui, H.1
Castro, L.2
Mendelsohn, J.3
-
83
-
-
0026744133
-
Mechanism and role of insulin receptor endocytosis
-
McClain DA. 1992. Mechanism and role of insulin receptor endocytosis. Am J Med Sci 304: 192-201.
-
(1992)
Am J Med Sci
, vol.304
, pp. 192-201
-
-
McClain, D.A.1
-
84
-
-
4143080425
-
AMSH is an endosome-associated ubiquitin isopeptidase
-
McCullough J, Clague MJ, Urbe S. 2004. AMSH is an endosome-associated ubiquitin isopeptidase. J Cell Biol 166: 487-492.
-
(2004)
J Cell Biol
, vol.166
, pp. 487-492
-
-
McCullough, J.1
Clague, M.J.2
Urbe, S.3
-
85
-
-
30944464589
-
Activation of the endosomeassociated ubiquitin isopeptidase AMSH by STAM, a component of the multivesicular body-sorting machinery
-
McCullough J, Row PE, Lorenzo O, Doherty M, Beynon R, Clague M.J., Urbe S. 2006. Activation of the endosomeassociated ubiquitin isopeptidase AMSH by STAM, a component of the multivesicular body-sorting machinery. Curr Biol 16: 160-165.
-
(2006)
Curr Biol
, vol.16
, pp. 160-165
-
-
McCullough, J.1
Row, P.E.2
Lorenzo, O.3
Doherty, M.4
Beynon, R.5
Clague, M.J.6
Urbe, S.7
-
86
-
-
0022602283
-
Localization of the epidermal growth factor (EGF) receptor within the endosome of EGF-stimulated epidermoid carcinoma (A431) cells
-
Miller K., Beardmore J, Kanety H, Schlessinger J, Hopkins CR. 1986. Localization of the epidermal growth factor (EGF) receptor within the endosome of EGF-stimulated epidermoid carcinoma (A431) cells. J Cell Biol 102: 500-509.
-
(1986)
J Cell Biol
, vol.102
, pp. 500-509
-
-
Miller, K.1
Beardmore, J.2
Kanety, H.3
Schlessinger, J.4
Hopkins, C.R.5
-
87
-
-
0032696038
-
Regulated migration of epidermal growth factor receptor from caveolae
-
Mineo C., Gill GN, Anderson RG. 1999. Regulated migration of epidermal growth factor receptor from caveolae. J Biol Chem 274: 30636-30643.
-
(1999)
J Biol Chem
, vol.274
, pp. 30636-30643
-
-
Mineo, C.1
Gill, G.N.2
Anderson, R.G.3
-
88
-
-
0033523010
-
Cbl-mediated negative regulation of platelet-derived growth factor receptor-dependent cell proliferation. A critical role for Cbl tyrosine kinase-binding domain
-
Miyake S., Mullane-Robinson KP, Lill NL, Douillard P, Band H. 1999. Cbl-mediated negative regulation of platelet-derived growth factor receptor-dependent cell proliferation. A critical role for Cbl tyrosine kinase-binding domain. J Biol Chem 274: 16619-16628.
-
(1999)
J Biol Chem
, vol.274
, pp. 16619-16628
-
-
Miyake, S.1
Mullane-Robinson, K.P.2
Lill, N.L.3
Douillard, P.4
Band, H.5
-
89
-
-
27644438783
-
Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes
-
Mizuno E., Iura T, Mukai A, Yoshimori T, Kitamura N, Komada M. 2005. Regulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomes. Mol Biol Cell 16: 5163-5174.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 5163-5174
-
-
Mizuno, E.1
Iura, T.2
Mukai, A.3
Yoshimori, T.4
Kitamura, N.5
Komada, M.6
-
90
-
-
33745754789
-
A deubiquitinating enzyme UBPY regulates the level of protein ubiquitination on endosomes
-
Mizuno E., Kobayashi K, Yamamoto A, Kitamura N, Komada M. 2006. A deubiquitinating enzyme UBPY regulates the level of protein ubiquitination on endosomes. Traffic 7: 1017-1031.
-
(2006)
Traffic
, vol.7
, pp. 1017-1031
-
-
Mizuno, E.1
Kobayashi, K.2
Yamamoto, A.3
Kitamura, N.4
Komada, M.5
-
91
-
-
46049089636
-
Grb10/Nedd4-mediated multiubiquitination of the insulin-like growth factor receptor regulates receptor internalization
-
Monami G., Emiliozzi V, Morrione A. 2008. Grb10/Nedd4-mediated multiubiquitination of the insulin-like growth factor receptor regulates receptor internalization. J Cell Physiol 216: 426-437.
-
(2008)
J Cell Physiol
, vol.216
, pp. 426-437
-
-
Monami, G.1
Emiliozzi, V.2
Morrione, A.3
-
92
-
-
0026664626
-
Ligand-induced polyubiquitination of the platelet-derived growth factor β-receptor
-
Mori S., Heldin CH, Claesson-Welsh L. 1992. Ligand-induced polyubiquitination of the platelet-derived growth factor β-receptor. J Biol Chem 267: 6429-6434.
-
(1992)
J Biol Chem
, vol.267
, pp. 6429-6434
-
-
Mori, S.1
Heldin, C.H.2
Claesson-Welsh, L.3
-
93
-
-
0030462362
-
Mutation of Dileucine residues in the juxtamembrane region alters EGF receptor expression
-
Morrison P., Chung KC, Rosner MR. 1996. Mutation of Dileucine residues in the juxtamembrane region alters EGF receptor expression. Biochemistry 35: 14618-14624.
-
(1996)
Biochemistry
, vol.35
, pp. 14618-14624
-
-
Morrison, P.1
Chung, K.C.2
Rosner, M.R.3
-
94
-
-
0033522506
-
Inhibition of the receptor-binding function of clathrin adaptor protein AP-2 by dominant-negative mutant m2 subunit and its effects on endocytosis
-
Nesterov A., Carter RE, Sorkina T, Gill GN, Sorkin A. 1999. Inhibition of the receptor-binding function of clathrin adaptor protein AP-2 by dominant-negative mutant m2 subunit and its effects on endocytosis. EMBO J 18: 2489-2499.
-
(1999)
EMBO J
, vol.18
, pp. 2489-2499
-
-
Nesterov, A.1
Carter, R.E.2
Sorkina, T.3
Gill, G.N.4
Sorkin, A.5
-
95
-
-
34347346071
-
Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo
-
Niendorf S., Oksche A, Kisser A, Lohler J, Prinz M, Schorle H., Feller S, Lewitzky M, Horak I, Knobeloch KP. 2007. Essential role of ubiquitin-specific protease 8 for receptor tyrosine kinase stability and endocytic trafficking in vivo. Mol Cell Biol 27: 5029-5039.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 5029-5039
-
-
Niendorf, S.1
Oksche, A.2
Kisser, A.3
Lohler, J.4
Prinz, M.5
Schorle, H.6
Feller, S.7
Lewitzky, M.8
Horak, I.9
Knobeloch, K.P.10
-
96
-
-
33645741605
-
A novel endocytic mechanism of epidermal growth factor receptor sequestration and internalization
-
Orth J.D., Krueger EW, Weller SG, McNiven MA. 2006. A novel endocytic mechanism of epidermal growth factor receptor sequestration and internalization. Cancer Res 66: 3603-3610.
-
(2006)
Cancer Res
, vol.66
, pp. 3603-3610
-
-
Orth, J.D.1
Krueger, E.W.2
Weller, S.G.3
McNiven, M.A.4
-
97
-
-
79958214335
-
GGA3 functions as a switch to promote Met receptor recycling, essential for sustained ERK and cell migration
-
Parachoniak C.A., Luo Y, Abella JV, Keen JH, Park M. 2011. GGA3 functions as a switch to promote Met receptor recycling, essential for sustained ERK and cell migration. Dev Cell 20: 751-763.
-
(2011)
Dev Cell
, vol.20
, pp. 751-763
-
-
Parachoniak, C.A.1
Luo, Y.2
Abella, J.V.3
Keen, J.H.4
Park, M.5
-
98
-
-
0037534097
-
c-Cbl is a critical modulator of the Ron tyrosine kinase receptor
-
Penengo L., Rubin C, Yarden Y, Gaudino G. 2003. c-Cbl is a critical modulator of the Ron tyrosine kinase receptor. Oncogene 22: 3669-3679.
-
(2003)
Oncogene
, vol.22
, pp. 3669-3679
-
-
Penengo, L.1
Rubin, C.2
Yarden, Y.3
Gaudino, G.4
-
99
-
-
80155192453
-
Nedd4-1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function
-
Persaud A., Alberts P, Hayes M, Guettler S, Clarke I, Sicheri F, Dirks P., Ciruna B, Rotin D. 2011. Nedd4-1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function. EMBO J 30: 3259-3273.
-
(2011)
EMBO J
, vol.30
, pp. 3259-3273
-
-
Persaud, A.1
Alberts, P.2
Hayes, M.3
Guettler, S.4
Clarke, I.5
Sicheri, F.6
Dirks, P.7
Ciruna, B.8
Rotin, D.9
-
100
-
-
0035930341
-
Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein
-
Peschard P., Fournier TM, Lamorte L, Naujokas MA, Band H., Langdon WY, Park M. 2001. Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein. Mol Cell 8: 995-1004.
-
(2001)
Mol Cell
, vol.8
, pp. 995-1004
-
-
Peschard, P.1
Fournier, T.M.2
Lamorte, L.3
Naujokas, M.A.4
Band, H.5
Langdon, W.Y.6
Park, M.7
-
101
-
-
0037075606
-
The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met
-
Petrelli A., Gilestro GF, Lanzardo S, Comoglio PM, Migone N, Giordano S. 2002. The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met. Nature 416: 187-190.
-
(2002)
Nature
, vol.416
, pp. 187-190
-
-
Petrelli, A.1
Gilestro, G.F.2
Lanzardo, S.3
Comoglio, P.M.4
Migone, N.5
Giordano, S.6
-
102
-
-
0842303313
-
Back to the future with ubiquitin
-
Pickart CM. 2004. Back to the future with ubiquitin. Cell 116: 181-190.
-
(2004)
Cell
, vol.116
, pp. 181-190
-
-
Pickart, C.M.1
-
103
-
-
78349252732
-
Eph/ephrin molecules-A hub for signaling and endocytosis
-
Pitulescu M.E., Adams RH. 2010. Eph/ephrin molecules-A hub for signaling and endocytosis. Genes Dev 24: 2480-2492.
-
(2010)
Genes Dev
, vol.24
, pp. 2480-2492
-
-
Pitulescu, M.E.1
Adams, R.H.2
-
104
-
-
0028263801
-
Human insulin-like growth factor I receptor internalization. Role of the juxtamembrane domain
-
Prager D., Li HL, Yamasaki H, Melmed S. 1994. Human insulin-like growth factor I receptor internalization. Role of the juxtamembrane domain. J Biol Chem 269: 11934-11937.
-
(1994)
J Biol Chem
, vol.269
, pp. 11934-11937
-
-
Prager, D.1
Li, H.L.2
Yamasaki, H.3
Melmed, S.4
-
105
-
-
1542714469
-
Interactions of GGA3 with the ubiquitin sorting machinery
-
Puertollano R., Bonifacino JS. 2004. Interactions of GGA3 with the ubiquitin sorting machinery. Nat Cell Biol 6: 244-251.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 244-251
-
-
Puertollano, R.1
Bonifacino, J.S.2
-
106
-
-
79960060557
-
Regulation of EGFR protein stability by the HECT-type ubiquitin ligase SMURF2
-
Ray D., Ahsan A, Helman A, Chen G, Hegde A, Gurjar SR, Zhao L., Kiyokawa H, Beer DG, Lawrence TS, et al. 2011. Regulation of EGFR protein stability by the HECT-type ubiquitin ligase SMURF2. Neoplasia 13: 570-578.
-
(2011)
Neoplasia
, vol.13
, pp. 570-578
-
-
Ray, D.1
Ahsan, A.2
Helman, A.3
Chen, G.4
Hegde, A.5
Gurjar, S.R.6
Zhao, L.7
Kiyokawa, H.8
Beer, D.G.9
Lawrence, T.S.10
-
107
-
-
77949567362
-
VHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargo
-
Ren X., Hurley JH. 2010. VHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargo. EMBO J 29: 1045-1054.
-
(2010)
EMBO J
, vol.29
, pp. 1045-1054
-
-
Ren, X.1
Hurley, J.H.2
-
108
-
-
0041843750
-
An integrated model of epidermal growth factor receptor trafficking and signal transduction
-
Resat H., Ewald JA, Dixon DA, Wiley HS. 2003. An integrated model of epidermal growth factor receptor trafficking and signal transduction. Biophys J 85: 730-743.
-
(2003)
Biophys J
, vol.85
, pp. 730-743
-
-
Resat, H.1
Ewald, J.A.2
Dixon, D.A.3
Wiley, H.S.4
-
109
-
-
67649889124
-
Differential effects of EGFR ligands on endocytic sorting of the receptor
-
Roepstorff K., Grandal MV, Henriksen L, Knudsen SL, Lerdrup M., Grovdal L, Willumsen BM, van Deurs B. 2009. Differential effects of EGFR ligands on endocytic sorting of the receptor. Traffic 10: 1115-1127.
-
(2009)
Traffic
, vol.10
, pp. 1115-1127
-
-
Roepstorff, K.1
Grandal, M.V.2
Henriksen, L.3
Knudsen, S.L.4
Lerdrup, M.5
Grovdal, L.6
Willumsen, B.M.7
van Deurs, B.8
-
110
-
-
79959367966
-
CIN85 regulates ubiquitination and degradative endosomal sorting of the EGF receptor
-
Ronning S.B., Pedersen NM, Madshus IH, Stang E. 2011. CIN85 regulates ubiquitination and degradative endosomal sorting of the EGF receptor. Exp Cell Res 317: 1804-1816.
-
(2011)
Exp Cell Res
, vol.317
, pp. 1804-1816
-
-
Ronning, S.B.1
Pedersen, N.M.2
Madshus, I.H.3
Stang, E.4
-
111
-
-
67349132223
-
Physiological functions of the HECT family of ubiquitin ligases
-
Rotin D., Kumar S. 2009. Physiological functions of the HECT family of ubiquitin ligases. Nat Rev Mol Cell Biol 10: 398-409.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 398-409
-
-
Rotin, D.1
Kumar, S.2
-
112
-
-
33646788800
-
The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor downregulation
-
Row P.E., Prior IA, McCullough J, Clague MJ, Urbe S. 2006. The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor downregulation. J Biol Chem 281: 12618-12624.
-
(2006)
J Biol Chem
, vol.281
, pp. 12618-12624
-
-
Row, P.E.1
Prior, I.A.2
McCullough, J.3
Clague, M.J.4
Urbe, S.5
-
113
-
-
78649789268
-
IGF-IR internalizes with Caveolin-1 and PTRF/Cavin in HaCat cells
-
Salani B., Passalacqua M, Maffioli S, Briatore L, Hamoudane M, Contini P, Cordera R, Maggi D. 2010. IGF-IR internalizes with Caveolin-1 and PTRF/Cavin in HaCat cells. PloS ONE 5: e14157.
-
(2010)
PloS ONE
, vol.5
-
-
Salani, B.1
Passalacqua, M.2
Maffioli, S.3
Briatore, L.4
Hamoudane, M.5
Contini, P.6
Cordera, R.7
Maggi, D.8
-
114
-
-
4744365071
-
Alix/AIP1 antagonizes epidermal growth factor receptor downregulation by the Cbl-SETA/CIN85 complex
-
Schmidt M.H., Hoeller D, Yu J, Furnari FB, Cavenee WK, Dikic I., Bogler O. 2004. Alix/AIP1 antagonizes epidermal growth factor receptor downregulation by the Cbl-SETA/CIN85 complex. Mol Cell Biol 24: 8981-8993.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8981-8993
-
-
Schmidt, M.H.1
Hoeller, D.2
Yu, J.3
Furnari, F.B.4
Cavenee, W.K.5
Dikic, I.6
Bogler, O.7
-
115
-
-
48649110734
-
Identification of c-Cbl as a new ligase for insulin-like growth factor-I receptor with distinct roles fromMdm2 in receptor ubiquitination and endocytosis
-
Sehat B., Andersson S, Girnita L, Larsson O. 2008. Identification of c-Cbl as a new ligase for insulin-like growth factor-I receptor with distinct roles fromMdm2 in receptor ubiquitination and endocytosis. Cancer Res 68: 5669-5677.
-
(2008)
Cancer Res
, vol.68
, pp. 5669-5677
-
-
Sehat, B.1
Andersson, S.2
Girnita, L.3
Larsson, O.4
-
116
-
-
14544306526
-
Clathrin-independent endocytosis of ubiquitinated cargos
-
Sigismund S., Woelk T, Puri C, Maspero E, Tacchetti C, Transidico P., Di Fiore PP, Polo S. 2005. Clathrin-independent endocytosis of ubiquitinated cargos. Proc Natl Acad Sci 102: 2760-2765.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 2760-2765
-
-
Sigismund, S.1
Woelk, T.2
Puri, C.3
Maspero, E.4
Tacchetti, C.5
Transidico, P.6
Di Fiore, P.P.7
Polo, S.8
-
117
-
-
0027249993
-
Interaction of activated EGF receptors with coated pit adaptins
-
Sorkin A., Carpenter G. 1993. Interaction of activated EGF receptors with coated pit adaptins. Science 261: 612-615.
-
(1993)
Science
, vol.261
, pp. 612-615
-
-
Sorkin, A.1
Carpenter, G.2
-
118
-
-
0026056927
-
Recycling of epidermal growth factor-receptor complexes in A431 cells: Identification of dual pathways
-
Sorkin A., Krolenko S, Kudrjavtceva N, Lazebnik J, Teslenko L, Soderquist AM, Nikolsky N. 1991. Recycling of epidermal growth factor-receptor complexes in A431 cells: Identification of dual pathways. J Cell Biol 112: 55-63.
-
(1991)
J Cell Biol
, vol.112
, pp. 55-63
-
-
Sorkin, A.1
Krolenko, S.2
Kudrjavtceva, N.3
Lazebnik, J.4
Teslenko, L.5
Soderquist, A.M.6
Nikolsky, N.7
-
119
-
-
0029889579
-
Epidermal growth factor receptor interaction with clathrin adaptors is mediated by the Tyr974-containing internalization motif
-
Sorkin A., Mazzotti M, Sorkina T, Scotto L, Beguinot L. 1996. Epidermal growth factor receptor interaction with clathrin adaptors is mediated by the Tyr974-containing internalization motif. J Biol Chem 271: 13377-13384.
-
(1996)
J Biol Chem
, vol.271
, pp. 13377-13384
-
-
Sorkin, A.1
Mazzotti, M.2
Sorkina, T.3
Scotto, L.4
Beguinot, L.5
-
120
-
-
0037075547
-
Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors
-
Soubeyran P., Kowanetz K, Szymkiewicz I, Langdon WY, Dikic I. 2002. Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors. Nature 416: 183-187.
-
(2002)
Nature
, vol.416
, pp. 183-187
-
-
Soubeyran, P.1
Kowanetz, K.2
Szymkiewicz, I.3
Langdon, W.Y.4
Dikic, I.5
-
121
-
-
0021219986
-
Characterization of the metabolic turnover of epidermal growth factor receptor protein in A-431 cells
-
Stoscheck C.M., Carpenter G. 1984. Characterization of the metabolic turnover of epidermal growth factor receptor protein in A-431 cells. J Cell Physiol 120: 296-302.
-
(1984)
J Cell Physiol
, vol.120
, pp. 296-302
-
-
Stoscheck, C.M.1
Carpenter, G.2
-
122
-
-
18244372679
-
Ubiquitin-interacting motifs of Epsin are involved in the regulation of insulin-dependent endocytosis
-
Sugiyama S., Kishida S, Chayama K, Koyama S, Kikuchi A. 2005. Ubiquitin-interacting motifs of Epsin are involved in the regulation of insulin-dependent endocytosis. J Biochem 137: 355-364.
-
(2005)
J Biochem
, vol.137
, pp. 355-364
-
-
Sugiyama, S.1
Kishida, S.2
Chayama, K.3
Koyama, S.4
Kikuchi, A.5
-
123
-
-
35248849299
-
Grb2 mediates negative regulation of stem cell factor receptor/ c-Kit signaling by recruitment of Cbl
-
Sun J., Pedersen M, Bengtsson S, Ronnstrand L. 2007. Grb2 mediates negative regulation of stem cell factor receptor/ c-Kit signaling by recruitment of Cbl. Exp Cell Res 313: 3935-3942.
-
(2007)
Exp Cell Res
, vol.313
, pp. 3935-3942
-
-
Sun, J.1
Pedersen, M.2
Bengtsson, S.3
Ronnstrand, L.4
-
124
-
-
41949128060
-
Isoform-specific monoubiquitination, endocytosis, and degradation of alternatively spliced ErbB4 isoforms
-
Sundvall M., Korhonen A, Paatero I, Gaudio E, Melino G, Croce C.M., Aqeilan RI, Elenius K. 2008. Isoform-specific monoubiquitination, endocytosis, and degradation of alternatively spliced ErbB4 isoforms. Proc Natl Acad Sci 105: 4162-4167.
-
(2008)
Proc Natl Acad Sci
, vol.105
, pp. 4162-4167
-
-
Sundvall, M.1
Korhonen, A.2
Paatero, I.3
Gaudio, E.4
Melino, G.5
Croce, C.M.6
Aqeilan, R.I.7
Elenius, K.8
-
125
-
-
0037131177
-
CIN85 participates in Cblb-mediated down-regulation of receptor tyrosine kinases
-
Szymkiewicz I., Kowanetz K, Soubeyran P, Dinarina A, Lipkowitz S., Dikic I. 2002. CIN85 participates in Cblb-mediated down-regulation of receptor tyrosine kinases. J Biol Chem 277: 39666-39672.
-
(2002)
J Biol Chem
, vol.277
, pp. 39666-39672
-
-
Szymkiewicz, I.1
Kowanetz, K.2
Soubeyran, P.3
Dinarina, A.4
Lipkowitz, S.5
Dikic, I.6
-
126
-
-
79958128563
-
Ligand-induced downregulation of TrkA is partly regulated through ubiquitination by Cbl
-
Takahashi Y., Shimokawa N, Esmaeili-Mahani S, Morita A, Masuda H., Iwasaki T, Tamura J, Haglund K, Koibuchi N. 2011. Ligand-induced downregulation of TrkA is partly regulated through ubiquitination by Cbl. FEBS Lett 585: 1741-1747.
-
(2011)
FEBS Lett
, vol.585
, pp. 1741-1747
-
-
Takahashi, Y.1
Shimokawa, N.2
Esmaeili-Mahani, S.3
Morita, A.4
Masuda, H.5
Iwasaki, T.6
Tamura, J.7
Haglund, K.8
Koibuchi, N.9
-
127
-
-
23044455604
-
Low density lipoprotein receptor-related protein 1 (LRP1) controls endocytosis and c-CBL-mediated ubiquitination of the platelet-derived growth factor receptor b (PDGFR b)
-
Takayama Y., May P, Anderson RG, Herz J. 2005. Low density lipoprotein receptor-related protein 1 (LRP1) controls endocytosis and c-CBL-mediated ubiquitination of the platelet-derived growth factor receptor b (PDGFR b). J Biol Chem 280: 18504-18510.
-
(2005)
J Biol Chem
, vol.280
, pp. 18504-18510
-
-
Takayama, Y.1
May, P.2
Anderson, R.G.3
Herz, J.4
-
128
-
-
0033516556
-
Possible involvement of a novel STAM-associated molecule "AMSH" in intracellular signal transduction mediated by cytokines
-
Tanaka N., Kaneko K, Asao H, Kasai H, Endo Y, Fujita T, Takeshita T., Sugamura K. 1999. Possible involvement of a novel STAM-associated molecule "AMSH" in intracellular signal transduction mediated by cytokines. J Biol Chem 274: 19129-19135.
-
(1999)
J Biol Chem
, vol.274
, pp. 19129-19135
-
-
Tanaka, N.1
Kaneko, K.2
Asao, H.3
Kasai, H.4
Endo, Y.5
Fujita, T.6
Takeshita, T.7
Sugamura, K.8
-
129
-
-
0029826531
-
Eps15 is a component of clathrin-coated pits and vesicles and is located at the rim of coated pits
-
Tebar F., Sorkina T, Sorkin A, Ericsson M, Kirchhausen T. 1996. Eps15 is a component of clathrin-coated pits and vesicles and is located at the rim of coated pits. J Biol Chem 271: 28727-28730.
-
(1996)
J Biol Chem
, vol.271
, pp. 28727-28730
-
-
Tebar, F.1
Sorkina, T.2
Sorkin, A.3
Ericsson, M.4
Kirchhausen, T.5
-
130
-
-
63049124957
-
SnapShot: The ESCRT machinery
-
Teis D., Saksena S, Emr SD. 2009. SnapShot: The ESCRT machinery. Cell 137: 182-182 e181.
-
(2009)
Cell
, vol.137
-
-
Teis, D.1
Saksena, S.2
Emr, S.D.3
-
131
-
-
24944538477
-
Negative regulation of PTK signalling by Cbl proteins
-
Thien C.B., Langdon WY. 2005. Negative regulation of PTK signalling by Cbl proteins. Growth Factors 23: 161-167.
-
(2005)
Growth Factors
, vol.23
, pp. 161-167
-
-
Thien, C.B.1
Langdon, W.Y.2
-
132
-
-
69249135065
-
Tickets to ride: Selecting cargo for clathrinregulated internalization
-
Traub LM. 2009. Tickets to ride: Selecting cargo for clathrinregulated internalization. Nat Rev Mol Cell Biol 10: 583-596.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 583-596
-
-
Traub, L.M.1
-
133
-
-
33751270407
-
Control of growth factor receptor dynamics by reversible ubiquitination
-
Urbe S., McCullough J, Row P, Prior IA, Welchman R, Clague MJ. 2006. Control of growth factor receptor dynamics by reversible ubiquitination. Biochem Soc Trans 34: 754-756.
-
(2006)
Biochem Soc Trans
, vol.34
, pp. 754-756
-
-
Urbe, S.1
McCullough, J.2
Row, P.3
Prior, I.A.4
Welchman, R.5
Clague, M.J.6
-
134
-
-
34547620177
-
Trk-signaling endosomes are generated by Rac-dependent macroendocytosis
-
Valdez G., Philippidou P, Rosenbaum J, Akmentin W, Shao Y, Halegoua S. 2007. Trk-signaling endosomes are generated by Rac-dependent macroendocytosis. Proc Natl Acad Sci 104: 12270-12275.
-
(2007)
Proc Natl Acad Sci
, vol.104
, pp. 12270-12275
-
-
Valdez, G.1
Philippidou, P.2
Rosenbaum, J.3
Akmentin, W.4
Shao, Y.5
Halegoua, S.6
-
135
-
-
1342304089
-
Solution conformation of Lys63-linked di-ubiquitin chain provides clues to functional diversity of polyubiquitin signaling
-
Varadan R., Assfalg M, Haririnia A, Raasi S, Pickart C, Fushman D. 2004. Solution conformation of Lys63-linked di-ubiquitin chain provides clues to functional diversity of polyubiquitin signaling. J Biol Chem 279: 7055-7063.
-
(2004)
J Biol Chem
, vol.279
, pp. 7055-7063
-
-
Varadan, R.1
Assfalg, M.2
Haririnia, A.3
Raasi, S.4
Pickart, C.5
Fushman, D.6
-
136
-
-
0345381737
-
The Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptor
-
Vecchione A., Marchese A, Henry P, Rotin D, Morrione A. 2003. The Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptor. Mol Cell Biol 23: 3363-3372.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 3363-3372
-
-
Vecchione, A.1
Marchese, A.2
Henry, P.3
Rotin, D.4
Morrione, A.5
-
137
-
-
79961140522
-
Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition
-
von Kleist L, Stahlschmidt W, Bulut H, Gromova K, Puchkov D., Robertson MJ, MacGregor KA, Tomilin N, Pechstein A., Chau N, et al. 2011. Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition. Cell 146: 471-484.
-
(2011)
Cell
, vol.146
, pp. 471-484
-
-
von Kleist, L.1
Stahlschmidt, W.2
Bulut, H.3
Gromova, K.4
Puchkov, D.5
Robertson, M.J.6
McGregor, K.A.7
Tomilin, N.8
Pechstein, A.9
Chau, N.10
-
138
-
-
79951933973
-
D-Cbl binding to Drk leads to dosedependent down-regulation of EGFR signaling and increases receptor-ligand endocytosis
-
Wang P.Y., Pai LM. 2011. D-Cbl binding to Drk leads to dosedependent down-regulation of EGFR signaling and increases receptor-ligand endocytosis. PloS ONE 6: e17097.
-
(2011)
PloS ONE
, vol.6
-
-
Wang, P.Y.1
Pai, L.M.2
-
139
-
-
0036469898
-
A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling
-
Waterman H., Katz M, Rubin C, Shtiegman K, Lavi S, Elson A., Jovin T, Yarden Y. 2002. A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling. EMBO J 21: 303-313.
-
(2002)
EMBO J
, vol.21
, pp. 303-313
-
-
Waterman, H.1
Katz, M.2
Rubin, C.3
Shtiegman, K.4
Lavi, S.5
Elson, A.6
Jovin, T.7
Yarden, Y.8
-
140
-
-
30444456831
-
EGF stimulates annexin 1-dependent inward vesiculation in a multivesicular endosome subpopulation
-
White I.J., Bailey LM, Aghakhani MR, Moss SE, Futter CE. 2006. EGF stimulates annexin 1-dependent inward vesiculation in a multivesicular endosome subpopulation. EMBO J 25: 1-12.
-
(2006)
EMBO J
, vol.25
, pp. 1-12
-
-
White, I.J.1
Bailey, L.M.2
Aghakhani, M.R.3
Moss, S.E.4
Futter, C.E.5
-
141
-
-
3242700634
-
Signaling, internalization, and intracellular activity of fibroblast growth factor
-
Wiedlocha A., Sorensen V. 2004. Signaling, internalization, and intracellular activity of fibroblast growth factor. Curr Top Microbiol Immunol 286: 45-79.
-
(2004)
Curr Top Microbiol Immunol
, vol.286
, pp. 45-79
-
-
Wiedlocha, A.1
Sorensen, V.2
-
142
-
-
0023677140
-
Anomalous binding of epidermal growth factor to A431 cells is due to the effect of high receptor densities and a saturable endocytic system
-
Wiley HS. 1988. Anomalous binding of epidermal growth factor to A431 cells is due to the effect of high receptor densities and a saturable endocytic system. J Cell Biol 107: 801-810.
-
(1988)
J Cell Biol
, vol.107
, pp. 801-810
-
-
Wiley, H.S.1
-
143
-
-
0037034167
-
C-Cbl binds the CSF-1 receptor at tyrosine 973, a novel phosphorylation site in the receptor's carboxy-terminus
-
Wilhelmsen K., Burkhalter S, van der Geer P. 2002. C-Cbl binds the CSF-1 receptor at tyrosine 973, a novel phosphorylation site in the receptor's carboxy-terminus. Oncogene 21: 1079-1089.
-
(2002)
Oncogene
, vol.21
, pp. 1079-1089
-
-
Wilhelmsen, K.1
Burkhalter, S.2
van der Geer, P.3
-
144
-
-
0037119950
-
Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling
-
Wong E.S., Fong CW, Lim J, Yusoff P, Low BC, Langdon WY, Guy GR. 2002. Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling. EMBO J 21: 4796-4808.
-
(2002)
EMBO J
, vol.21
, pp. 4796-4808
-
-
Wong, E.S.1
Fong, C.W.2
Lim, J.3
Yusoff, P.4
Low, B.C.5
Langdon, W.Y.6
Guy, G.R.7
-
145
-
-
0142040128
-
YXXM motifs in the PDGF-b receptor serve dual roles as phosphoinositide 3-kinase binding motifs and tyrosine-based endocytic sorting signals
-
Wu H., Windmiller DA, Wang L, Backer JM. 2003a. YXXM motifs in the PDGF-b receptor serve dual roles as phosphoinositide 3-kinase binding motifs and tyrosine-based endocytic sorting signals. J Biol Chem 278: 40425-40428.
-
(2003)
J Biol Chem
, vol.278
, pp. 40425-40428
-
-
Wu, H.1
Windmiller, D.A.2
Wang, L.3
Backer, J.M.4
-
146
-
-
0141426629
-
Activated Cdc42 sequesters c-Cbl and prevents EGF receptor degradation
-
Wu W.J., Tu S, Cerione RA. 2003b. Activated Cdc42 sequesters c-Cbl and prevents EGF receptor degradation. Cell 114: 715-725.
-
(2003)
Cell
, vol.114
, pp. 715-725
-
-
Wu, W.J.1
Tu, S.2
Cerione, R.A.3
-
147
-
-
60649118104
-
The coming of age of axonal neurotrophin signaling endosomes
-
Wu C., Cui B, He L, Chen L, Mobley WC. 2009. The coming of age of axonal neurotrophin signaling endosomes. J Proteomics 72: 46-55.
-
(2009)
J Proteomics
, vol.72
, pp. 46-55
-
-
Wu, C.1
Cui, B.2
He, L.3
Chen, L.4
Mobley, W.C.5
-
148
-
-
54949103214
-
miR-296 regulates growth factor receptor overexpression in angiogenic endothelial cells
-
Wurdinger T., Tannous BA, Saydam O, Skog J, Grau S, Soutschek J, Weissleder R, Breakefield XO, Krichevsky AM. 2008. miR-296 regulates growth factor receptor overexpression in angiogenic endothelial cells. Cancer Cell 14: 382-393.
-
(2008)
Cancer Cell
, vol.14
, pp. 382-393
-
-
Wurdinger, T.1
Tannous, B.A.2
Saydam, O.3
Skog, J.4
Grau, S.5
Soutschek, J.6
Weissleder, R.7
Breakefield, X.O.8
Krichevsky, A.M.9
-
149
-
-
0036558279
-
Role of Grb2 in EGF-stimulated EGFR internalization
-
Yamazaki T., Zaal K, Hailey D, Presley J, Lippincott-Schwartz J, Samelson LE. 2002. Role of Grb2 in EGF-stimulated EGFR internalization. J Cell Sci 115: 1791-1802.
-
(2002)
J Cell Sci
, vol.115
, pp. 1791-1802
-
-
Yamazaki, T.1
Zaal, K.2
Hailey, D.3
Presley, J.4
Lippincott-Schwartz, J.5
Samelson, L.E.6
-
151
-
-
77951061655
-
Mig-6 controls EGFR trafficking and suppresses gliomagenesis
-
Ying H., Zheng H, Scott K, Wiedemeyer R, Yan H, Lim C, Huang J., Dhakal S, Ivanova E, Xiao Y, et al. 2010. Mig-6 controls EGFR trafficking and suppresses gliomagenesis. Proc Natl Acad Sci 107: 6912-6917.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 6912-6917
-
-
Ying, H.1
Zheng, H.2
Scott, K.3
Wiedemeyer, R.4
Yan, H.5
Lim, C.6
Huang, J.7
Dhakal, S.8
Ivanova, E.9
Xiao, Y.10
-
152
-
-
0033748123
-
Requirements of multiple domains of SLI-1, a Caenorhabditis elegans homologue of c-Cbl, and an inhibitory tyrosine in LET-23 in regulating vulval differentiation
-
Yoon C.H., Chang C, Hopper NA, Lesa GM, Sternberg PW. 2000. Requirements of multiple domains of SLI-1, a Caenorhabditis elegans homologue of c-Cbl, and an inhibitory tyrosine in LET-23 in regulating vulval differentiation. Mol Biol Cell 11: 4019-4031.
-
(2000)
Mol Biol Cell
, vol.11
, pp. 4019-4031
-
-
Yoon, C.H.1
Chang, C.2
Hopper, N.A.3
Lesa, G.M.4
Sternberg, P.W.5
-
153
-
-
0031730287
-
Nerve growth factor processing and trafficking events following TrkA-mediated endocytosis
-
Zapf-Colby A, Olefsky JM. 1998. Nerve growth factor processing and trafficking events following TrkA-mediated endocytosis. Endocrinology 139: 3232-3240.
-
(1998)
Endocrinology
, vol.139
, pp. 3232-3240
-
-
Zapf-Colby, A.1
Olefsky, J.M.2
-
154
-
-
11144244315
-
Regulation of stem cell factor receptor signaling by Cbl family proteins (Cbl-b/c-Cbl)
-
Zeng S., Xu Z, Lipkowitz S, Longley JB. 2005. Regulation of stem cell factor receptor signaling by Cbl family proteins (Cbl-b/c-Cbl). Blood 105: 226-232.
-
(2005)
Blood
, vol.105
, pp. 226-232
-
-
Zeng, S.1
Xu, Z.2
Lipkowitz, S.3
Longley, J.B.4
-
155
-
-
67649311930
-
Nedd4 mediates ErbB4 JM-a/ CYT-1 ICD ubiquitination and degradation in MDCK II cells
-
Zeng F., Xu J, Harris RC. 2009. Nedd4 mediates ErbB4 JM-a/ CYT-1 ICD ubiquitination and degradation in MDCK II cells. FASEB J 23: 1935-1945.
-
(2009)
FASEB J
, vol.23
, pp. 1935-1945
-
-
Zeng, F.1
Xu, J.2
Harris, R.C.3
-
156
-
-
45149133324
-
Clathrin-dependent endocytosis is required for TrkB-dependent Aktmediated neuronal protection and dendritic growth
-
Zheng J., Shen WH, Lu TJ, Zhou Y, Chen Q, Wang Z, Xiang T, Zhu Y.C., Zhang C, Duan S, et al. 2008. Clathrin-dependent endocytosis is required for TrkB-dependent Aktmediated neuronal protection and dendritic growth. J Biol Chem 283: 13280-13288.
-
(2008)
J Biol Chem
, vol.283
, pp. 13280-13288
-
-
Zheng, J.1
Shen, W.H.2
Lu, T.J.3
Zhou, Y.4
Chen, Q.5
Wang, Z.6
Xiang, T.7
Zhu, Y.C.8
Zhang, C.9
Duan, S.10
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