-
1
-
-
60849101584
-
Cross-repressive interactions between Lrig3 and netrin 1 shape the architecture of the inner ear
-
Abraira VE, Del Rio T, Tucker AF, Slonimsky J, Keirnes HL & Goodrich LV 2008 Cross-repressive interactions between Lrig3 and netrin 1 shape the architecture of the inner ear. Development 135 4091-4099. (doi:10.1242/dev.029330)
-
(2008)
Development
, vol.135
, pp. 4091-4099
-
-
Abraira, V.E.1
Del Rio, T.2
Tucker, A.F.3
Slonimsky, J.4
Keirnes, H.L.5
Goodrich, L.V.6
-
2
-
-
77749258762
-
Vertebrate Lrig3-ErbB interactions occur in vitro but are unlikely to play a role in Lrig3- dependent inner ear morphogenesis
-
Abraira VE, Satoh T, Fekete DM& Goodrich LV 2010 Vertebrate Lrig3-ErbB interactions occur in vitro but are unlikely to play a role in Lrig3- dependent inner ear morphogenesis. PLoS ONE 5 e8981. (doi:10.1371/ journal.pone.0008981)
-
(2010)
PLoS ONE
, vol.5
, pp. e8981
-
-
Abraira, V.E.1
Satoh, T.2
Fekete, D.M.3
Goodrich, L.V.4
-
3
-
-
10344239412
-
Netrin-1 and its receptors in tumorigenesis. Nature reviews
-
Arakawa H 2004 Netrin-1 and its receptors in tumorigenesis. Nature Reviews. Cancer 4 978-987. (doi:10.1038/nrc1504)
-
(2004)
Cancer
, vol.4
, pp. 978-987
-
-
Arakawa, H.1
-
4
-
-
77954221611
-
Severe voiding dysfunction: Ask the child to smile
-
Bacchetta J & Cochat P 2010 Severe voiding dysfunction: ask the child to smile. Kidney International 78 225-226. (doi:10.1038/ki.2010.144)
-
(2010)
Kidney International
, vol.78
, pp. 225-226
-
-
Bacchetta, J.1
Cochat, P.2
-
5
-
-
84863248798
-
LRIG1 modulates cancer cell sensitivity to Smac mimetics by regulating TNFa expression and receptor tyrosine kinase signaling
-
Bai L,McEachern D, Yang CY, Lu J, Sun H & Wang S 2012 LRIG1 modulates cancer cell sensitivity to Smac mimetics by regulating TNFa expression and receptor tyrosine kinase signaling. Cancer Research 72 1229-1238. (doi:10.1158/0008-5472.CAN-11-2428)
-
(2012)
Cancer Research
, vol.72
, pp. 1229-1238
-
-
Bai Lmceachern, D.1
Yang, C.Y.2
Lu, J.3
Sun, H.4
Wang, S.5
-
6
-
-
59049106578
-
Crypt stem cells as the cells-of-origin of intestinal cancer
-
Barker N, Ridgway RA, van Es JH, van de Wetering M, Begthel H, van den Born M, Danenberg E, Clarke AR, Sansom OJ & Clevers H 2009 Crypt stem cells as the cells-of-origin of intestinal cancer. Nature 457 608-611. (doi:10.1038/nature07602)
-
(2009)
Nature
, vol.457
, pp. 608-611
-
-
Barker, N.1
Ridgway, R.A.2
Van Es, J.H.3
Van De Wetering, M.4
Begthel, H.5
Van Den Born, M.6
Danenberg, E.7
Clarke, A.R.8
Sansom, O.J.9
Clevers, H.10
-
7
-
-
84866002291
-
The cBio cancer genomics portal: An open platform for exploring multidimensional cancer genomics data
-
Cerami E, Gao J, Dogrusoz U, Gross BE, Sumer SO, Aksoy BA, Jacobsen A, Byrne CJ, Heuer ML, Larsson E et al. 2012 The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discovery 2 401-404. (doi:10.1158/2159-8290.CD-12-0095)
-
(2012)
Cancer Discovery
, vol.2
, pp. 401-404
-
-
Cerami, E.1
Gao, J.2
Dogrusoz, U.3
Gross, B.E.4
Sumer, S.O.5
Aksoy, B.A.6
Jacobsen, A.7
Byrne, C.J.8
Heuer, M.L.9
Larsson, E.10
-
8
-
-
84889016843
-
Restoration of LRIG1 suppresses bladder cancer cell growth by directly targeting EGFR activity
-
Chang L, Shi R, Yang T, Li F, LiG, Guo Y, Lang B, Yang W, ZhuangQ & Xu H 2013 Restoration of LRIG1 suppresses bladder cancer cell growth by directly targeting EGFR activity. Journal of Experimental & Clinical Cancer Research 32 101. (doi:10.1186/1756-9966-32-101)
-
(2013)
Journal of Experimental & Clinical Cancer Research
, vol.32
, pp. 101
-
-
Chang, L.1
Shi, R.2
Yang, T.3
Li, F.4
Lig Guo, Y.5
Lang, B.6
Yang, W.7
Zhuang, Q.8
Xu, H.9
-
9
-
-
77953230330
-
Mutations in HPSE2 cause urofacial syndrome
-
Daly SB, Urquhart JE, Hilton E, McKenzie EA, Kammerer RA, Lewis M, Kerr B, Stuart H, Donnai D, Long DA et al. 2010 Mutations in HPSE2 cause urofacial syndrome. American Journal of Human Genetics 86 963-969. (doi:10.1016/j.ajhg.2010.05.006)
-
(2010)
American Journal of Human Genetics
, vol.86
, pp. 963-969
-
-
Daly, S.B.1
Urquhart, J.E.2
Hilton, E.3
McKenzie, E.A.4
Kammerer, R.A.5
Lewis, M.6
Kerr, B.7
Stuart, H.8
Donnai, D.9
Long, D.A.10
-
10
-
-
84884683694
-
In vivo analysis of Lrig genes reveals redundant and independent functions in the inner ear
-
Del Rio T, Nishitani AM, YuWM& Goodrich LV 2013 In vivo analysis of Lrig genes reveals redundant and independent functions in the inner ear. PLoS Genetics 9 e1003824. (doi:10.1371/journal.pgen.1003824)
-
(2013)
PLoS Genetics
, vol.9
, pp. e1003824
-
-
Del Rio, T.1
Nishitani, A.M.2
Yu, W.M.3
Goodrich, L.V.4
-
11
-
-
84875740314
-
Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal
-
Gao J, Aksoy BA, Dogrusoz U, Dresdner G, Gross B, Sumer SO, Sun Y, Jacobsen A, Sinha R, Larsson E et al. 2013 Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Science Signaling 6 pl1. (doi:10.1126/scisignal.2004088)
-
(2013)
Science Signaling
, vol.6
, pp. 11
-
-
Gao, J.1
Aksoy, B.A.2
Dogrusoz, U.3
Dresdner, G.4
Gross, B.5
Sumer, S.O.6
Sun, Y.7
Jacobsen, A.8
Sinha, R.9
Larsson, E.10
-
12
-
-
33846281874
-
A soluble ectodomain of LRIG1 inhibits cancer cell growth by attenuating basal and ligand-dependent EGFR activity
-
Goldoni S, Iozzo RA, Kay P, Campbell S, McQuillan A, Agnew C, Zhu JX, Keene DR, Reed CC & Iozzo RV 2007 A soluble ectodomain of LRIG1 inhibits cancer cell growth by attenuating basal and ligand-dependent EGFR activity. Oncogene 26 368-381. (doi:10.1038/sj.onc.1209803)
-
(2007)
Oncogene
, vol.26
, pp. 368-381
-
-
Goldoni, S.1
Iozzo, R.A.2
Kay, P.3
Campbell, S.4
McQuillan, A.5
Agnew, C.6
Zhu, J.X.7
Keene, D.R.8
Reed, C.C.9
Iozzo, R.V.10
-
13
-
-
77953187849
-
Caenorhabditis elegans SMA-10/LRIG is a conserved transmembrane protein that enhances bone morphogenetic protein signaling
-
Gumienny TL, Macneil L, Zimmerman CM, Wang H, Chin L, Wrana JL & Padgett RW 2010 Caenorhabditis elegans SMA-10/LRIG is a conserved transmembrane protein that enhances bone morphogenetic protein signaling. PLoS Genetics 6 e1000963. (doi:10.1371/journal.pgen. 1000963)
-
(2010)
PLoS Genetics
, vol.6
, pp. e1000963
-
-
Gumienny, T.L.1
Macneil, L.2
Zimmerman, C.M.3
Wang, H.4
Chin, L.5
Wrana, J.L.6
Padgett, R.W.7
-
14
-
-
2942534392
-
The LRIG gene family has three vertebrate paralogs widely expressed in human and mouse tissues and a homolog in Ascidiacea
-
Guo D, Holmlund C, Henriksson R & Hedman H 2004 The LRIG gene family has three vertebrate paralogs widely expressed in human and mouse tissues and a homolog in Ascidiacea. Genomics 84 157-165. (doi:10.1016/j.ygeno.2004.01.013)
-
(2004)
Genomics
, vol.84
, pp. 157-165
-
-
Guo, D.1
Holmlund, C.2
Henriksson, R.3
Hedman, H.4
-
15
-
-
33645561341
-
Perinuclear leucine-rich repeats and immunoglobulin- like domain proteins (LRIG1-3) as prognostic indicators in astrocytic tumors
-
Guo D, Nilsson J, Haapasalo H, Raheem O, Bergenheim T, Hedman H & Henriksson R 2006 Perinuclear leucine-rich repeats and immunoglobulin- like domain proteins (LRIG1-3) as prognostic indicators in astrocytic tumors. Acta Neuropathologica 111 238-246. (doi:10.1007/s00401-006-0032-5)
-
(2006)
Acta Neuropathologica
, vol.111
, pp. 238-246
-
-
Guo, D.1
Nilsson, J.2
Haapasalo, H.3
Raheem, O.4
Bergenheim, T.5
Hedman, H.6
Henriksson, R.7
-
16
-
-
20844462896
-
LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation
-
Gur G, Rubin C, KatzM, Amit I,Citri A, Nilsson J, Amariglio N, Henriksson R, Rechavi G, Hedman H et al. 2004 LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation. EMBO Journal 23 3270-3281. (doi:10.1038/sj.emboj.7600342)
-
(2004)
EMBO Journal
, vol.23
, pp. 3270-3281
-
-
Gur, G.1
Rubin, C.2
Katzm Amit Icitri, A.3
Nilsson, J.4
Amariglio, N.5
Henriksson, R.6
Rechavi, G.7
Hedman, H.8
-
17
-
-
70349750269
-
Investigating the targets of MIR- 15a and MIR-16-1 in patients with chronic lymphocytic leukemia (CLL)
-
Hanlon K, Rudin CE & Harries LW 2009 Investigating the targets of MIR- 15a and MIR-16-1 in patients with chronic lymphocytic leukemia (CLL). PLoS ONE 4 e7169. (doi:10.1371/journal.pone.0007169)
-
(2009)
PLoS ONE
, vol.4
, pp. e7169
-
-
Hanlon, K.1
Rudin, C.E.2
Harries, L.W.3
-
18
-
-
33947651745
-
LRIG inhibitors of growth factor signalling - Double-edged swords in human cancer?
-
Hedman H & Henriksson R 2007 LRIG inhibitors of growth factor signalling - double-edged swords in human cancer? European Journal of Cancer 43 676-682. (doi:10.1016/j.ejca.2006.10.021)
-
(2007)
European Journal of Cancer
, vol.43
, pp. 676-682
-
-
Hedman, H.1
Henriksson, R.2
-
19
-
-
0036352654
-
Is LRIG1 a tumour suppressor gene at chromosome 3p14.3?
-
Hedman H, Nilsson J, Guo D & Henriksson R 2002 Is LRIG1 a tumour suppressor gene at chromosome 3p14.3? Acta Oncologica 41 352-354. (doi:10.1080/028418602760169398)
-
(2002)
Acta Oncologica
, vol.41
, pp. 352-354
-
-
Hedman, H.1
Nilsson, J.2
Guo, D.3
Henriksson, R.4
-
20
-
-
77954472069
-
LRIG2 in contrast to LRIG1 predicts poor survival in early-stage squamous cell carcinoma of the uterine cervix
-
Hedman H, Lindstrom AK, Tot T, Stendahl U, Henriksson R & Hellberg D 2010 LRIG2 in contrast to LRIG1 predicts poor survival in early-stage squamous cell carcinoma of the uterine cervix. Acta Oncologica 49 812-815. (doi:10.3109/0284186X.2010.492789)
-
(2010)
Acta Oncologica
, vol.49
, pp. 812-815
-
-
Hedman, H.1
Lindstrom, A.K.2
Tot, T.3
Stendahl, U.4
Henriksson, R.5
Hellberg, D.6
-
21
-
-
2442526679
-
Characterization and tissue-specific expression of human LRIG2
-
Holmlund C, Nilsson J, Guo D, Starefeldt A, Golovleva I, Henriksson R & Hedman H 2004 Characterization and tissue-specific expression of human LRIG2. Gene 332 35-43. (doi:10.1016/j.gene.2004.02.002)
-
(2004)
Gene
, vol.332
, pp. 35-43
-
-
Holmlund, C.1
Nilsson, J.2
Guo, D.3
Starefeldt, A.4
Golovleva, I.5
Henriksson, R.6
Hedman, H.7
-
22
-
-
65649148276
-
Cytoplasmic LRIG2 expression is associated with poor oligodendroglioma patient survival
-
Holmlund C, Haapasalo H, Yi W, Raheem O, Brannstrom T, Bragge H, Henriksson R & Hedman H 2009 Cytoplasmic LRIG2 expression is associated with poor oligodendroglioma patient survival. Neuropathology 29 242-247. (doi:10.1111/j.1440-1789.2008.00970.x)
-
(2009)
Neuropathology
, vol.29
, pp. 242-247
-
-
Holmlund, C.1
Haapasalo, H.2
Yi, W.3
Raheem, O.4
Brannstrom, T.5
Bragge, H.6
Henriksson, R.7
Hedman, H.8
-
23
-
-
84892966364
-
Targeting tumor suppressor p53 for cancer therapy: Strategies, challenges and opportunities
-
Hong B, van den Heuvel AP, Prabhu VV, Zhang S & El-Deiry WS 2014 Targeting tumor suppressor p53 for cancer therapy: strategies, challenges and opportunities. Current Drug Targets 15 80-89. (doi:10.2174/1389450114666140106101412)
-
(2014)
Current Drug Targets
, vol.15
, pp. 80-89
-
-
Hong, B.1
Van Den Heuvel, A.P.2
Prabhu, V.V.3
Zhang, S.4
El-Deiry, W.S.5
-
24
-
-
33747047561
-
Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence
-
Jensen KB & Watt FM 2006 Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence. PNAS 103 11958-11963. (doi:10.1073/pnas.0601886103)
-
(2006)
PNAS
, vol.103
, pp. 11958-11963
-
-
Jensen, K.B.1
Watt, F.M.2
-
25
-
-
53949097156
-
A stem cell gene expression profile of human squamous cell carcinomas
-
Jensen KB, Jones J & Watt FM 2008 A stem cell gene expression profile of human squamous cell carcinomas. Cancer Letters 272 23-31. (doi:10.1016/j.canlet.2008.06.014)
-
(2008)
Cancer Letters
, vol.272
, pp. 23-31
-
-
Jensen, K.B.1
Jones, J.2
Watt, F.M.3
-
26
-
-
65349166258
-
Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis
-
Jensen KB, Collins CA, Nascimento E, Tan DW, Frye M, Itami S & Watt FM 2009 Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis. Cell Stem Cell 4 427-439. (doi:10.1016/j.stem.2009.04.014)
-
(2009)
Cell Stem Cell
, vol.4
, pp. 427-439
-
-
Jensen, K.B.1
Collins, C.A.2
Nascimento, E.3
Tan, D.W.4
Frye, M.5
Itami, S.6
Watt, F.M.7
-
27
-
-
84878611766
-
The soluble form of the tumor suppressor Lrig1 potently inhibits in vivo glioma growth irrespective of EGF receptor status
-
Johansson M, Oudin A, Tiemann K, Bernard A, Golebiewska A, Keunen O, Fack F, Stieber D,Wang B, Hedman H et al. 2013 The soluble form of the tumor suppressor Lrig1 potently inhibits in vivo glioma growth irrespective of EGF receptor status. Neuro-Oncology 15 1200-1211. (doi:10.1093/neuonc/not054)
-
(2013)
Neuro-Oncology
, vol.15
, pp. 1200-1211
-
-
Johansson, M.1
Oudin, A.2
Tiemann, K.3
Bernard, A.4
Golebiewska, A.5
Keunen, O.6
Fack, F.7
Stieber Dwang, B.8
Hedman, H.9
-
28
-
-
0035947724
-
Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells
-
Kao S, Jaiswal RK, Kolch W & Landreth GE 2001 Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells. Journal of Biological Chemistry 276 18169-18177. (doi:10.1074/jbc. M008870200)
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 18169-18177
-
-
Kao, S.1
Jaiswal, R.K.2
Kolch, W.3
Landreth, G.E.4
-
30
-
-
80054706404
-
Lrig1 is an estrogen-regulated growth suppressor and correlates with longer relapse-free survival in ERapositive breast cancer
-
Krig SR, Frietze S, Simion C,Miller JK, Fry WH, Rafidi H, Kotelawala L, Qi L, Griffith OL, Gray JW et al. 2011 Lrig1 is an estrogen-regulated growth suppressor and correlates with longer relapse-free survival in ERapositive breast cancer. Molecular Cancer Research 9 1406-1417. (doi:10.1158/1541-7786.MCR-11-0227)
-
(2011)
Molecular Cancer Research
, vol.9
, pp. 1406-1417
-
-
Krig, S.R.1
Frietze, S.2
Simion Cmiller, J.K.3
Fry, W.H.4
Rafidi, H.5
Kotelawala, L.6
Qi, L.7
Griffith, O.L.8
Gray, J.W.9
-
31
-
-
8744267487
-
The leucine-rich repeat protein LRIG1 is a negative regulator of ErbB family receptor tyrosine kinases
-
Laederich MB, Funes-Duran M, Yen L, Ingalla E, Wu X, Carraway KL III & Sweeney C 2004 The leucine-rich repeat protein LRIG1 is a negative regulator of ErbB family receptor tyrosine kinases. Journal of Biological Chemistry 279 47050-47056. (doi:10.1074/jbc.M409703200)
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 47050-47056
-
-
Laederich, M.B.1
Funes-Duran, M.2
Yen, L.3
Ingalla, E.4
Wu, X.5
Carraway, K.L.6
Sweeney, C.7
-
32
-
-
38149041753
-
Lrig1 is an endogenous inhibitor of Ret receptor tyrosine kinase activation, downstream signaling, and biological responses to GDNF
-
Ledda F, Bieraugel O, Fard SS, Vilar M & Paratcha G 2008 Lrig1 is an endogenous inhibitor of Ret receptor tyrosine kinase activation, downstream signaling, and biological responses to GDNF. Journal of Neuroscience 28 39-49. (doi:10.1523/JNEUROSCI.2196-07.2008)
-
(2008)
Journal of Neuroscience
, vol.28
, pp. 39-49
-
-
Ledda, F.1
Bieraugel, O.2
Fard, S.S.3
Vilar, M.4
Paratcha, G.5
-
33
-
-
84891742197
-
Cbl-independent degradation of Met: Ways to avoid agonism of bivalent Met-targeting antibody
-
Lee JM, Kim B, Lee SB, Jeong Y, Oh YM, Song YJ, Jung S, Choi J, Lee S, Cheong KH et al. 2014 Cbl-independent degradation of Met: ways to avoid agonism of bivalent Met-targeting antibody. Oncogene 33 34-43. (doi:10.1038/onc.2012.551)
-
(2014)
Oncogene
, vol.33
, pp. 34-43
-
-
Lee, J.M.1
Kim, B.2
Lee, S.B.3
Jeong, Y.4
Oh, Y.M.5
Song, Y.J.6
Jung, S.7
Choi, J.8
Lee, S.9
Cheong, K.H.10
-
34
-
-
79958204380
-
Suppression of bladder cancer cell tumorigenicity in an athymic mouse model by adenoviral vectormediated transfer of LRIG1
-
Li F, Ye ZQ, Guo DS & Yang WM 2011 Suppression of bladder cancer cell tumorigenicity in an athymic mouse model by adenoviral vectormediated transfer of LRIG1. Oncology Reports 26 439-446. (doi:10.3892/or.2011.1304)
-
(2011)
Oncology Reports
, vol.26
, pp. 439-446
-
-
Li, F.1
Ye, Z.Q.2
Guo, D.S.3
Yang, W.M.4
-
35
-
-
84897571254
-
Expression of LRIG1 is associated with good prognosis and human papillomavirus status in oropharyngeal cancer
-
Lindquist D, Nasman A, Tarjan M, Henriksson R, Tot T, Dalianis T & Hedman H 2014 Expression of LRIG1 is associated with good prognosis and human papillomavirus status in oropharyngeal cancer. British Journal of Cancer 110 1793-1800. (doi:10.1038/bjc.2014.87)
-
(2014)
British Journal of Cancer
, vol.110
, pp. 1793-1800
-
-
Lindquist, D.1
Nasman, A.2
Tarjan, M.3
Henriksson, R.4
Tot, T.5
Dalianis, T.6
Hedman, H.7
-
36
-
-
84874046969
-
LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development
-
Lu L, Teixeira VH, Yuan Z, Graham TA, Endesfelder D, Kolluri K, Al-Juffali N, Hamilton N, Nicholson AG, Falzon M et al. 2013 LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development. Journal of Pathology 229 608-620. (doi:10.1002/path.4148)
-
(2013)
Journal of Pathology
, vol.229
, pp. 608-620
-
-
Lu, L.1
Teixeira, V.H.2
Yuan, Z.3
Graham, T.A.4
Endesfelder, D.5
Kolluri, K.6
Al-Juffali, N.7
Hamilton, N.8
Nicholson, A.G.9
Falzon, M.10
-
37
-
-
0028344729
-
The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase
-
Luetteke NC, Phillips HK, Qiu TH, Copeland NG, Earp HS, Jenkins NA & Lee DC 1994 The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase. Genes and Development 8 399-413. (doi:10.1101/gad.8.4.399)
-
(1994)
Genes and Development
, vol.8
, pp. 399-413
-
-
Luetteke, N.C.1
Phillips, H.K.2
Qiu, T.H.3
Copeland, N.G.4
Earp, H.S.5
Jenkins, N.A.6
Lee, D.C.7
-
38
-
-
84873636387
-
A role for LRIG1 in the regulation of malignant glioma aggressiveness
-
Mao F, Wang B, Xiao Q, Xi G, Sun W, Zhang H, Ye F, Wan F, Guo D, Lei T et al. 2013 A role for LRIG1 in the regulation of malignant glioma aggressiveness. International Journal of Oncology 42 1081-1087.
-
(2013)
International Journal of Oncology
, vol.42
, pp. 1081-1087
-
-
Mao, F.1
Wang, B.2
Xiao, Q.3
Xi, G.4
Sun, W.5
Zhang, H.6
Ye, F.7
Wan, F.8
Guo, D.9
Lei, T.10
-
39
-
-
54249104578
-
Suppression of the negative regulator LRIG1 contributes to ErbB2 overexpression in breast cancer
-
Miller JK, Shattuck DL, Ingalla EQ, Yen L, Borowsky AD, Young LJ, Cardiff RD, Carraway KL III & Sweeney C 2008 Suppression of the negative regulator LRIG1 contributes to ErbB2 overexpression in breast cancer. Cancer Research 68 8286-8294. (doi:10.1158/0008-5472.CAN-07-6316)
-
(2008)
Cancer Research
, vol.68
, pp. 8286-8294
-
-
Miller, J.K.1
Shattuck, D.L.2
Ingalla, E.Q.3
Yen, L.4
Borowsky, A.D.5
Young, L.J.6
Cardiff, R.D.7
Carraway, K.L.8
Sweeney, C.9
-
40
-
-
0037656514
-
Identification of molecular subtypes of glioblastoma by gene expression profiling
-
Mischel PS, Shai R, Shi T, Horvath S, Lu KV, Choe G, Seligson D, Kremen TJ, Palotie A, Liau LM et al. 2003 Identification of molecular subtypes of glioblastoma by gene expression profiling. Oncogene 22 2361-2373. (doi:10.1038/sj.onc.1206344)
-
(2003)
Oncogene
, vol.22
, pp. 2361-2373
-
-
Mischel, P.S.1
Shai, R.2
Shi, T.3
Horvath, S.4
Lu, K.V.5
Choe, G.6
Seligson, D.7
Kremen, T.J.8
Palotie, A.9
Liau, L.M.10
-
41
-
-
0025015168
-
A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
-
Moser AR, Pitot HC & Dove WF 1990 A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 247 322-324. (doi:10.1126/science.2296722)
-
(1990)
Science
, vol.247
, pp. 322-324
-
-
Moser, A.R.1
Pitot, H.C.2
Dove, W.F.3
-
42
-
-
84873614833
-
Expression of LRIG1 and LRIG3 correlates with human papillomavirus status and patient survival in cervical adenocarcinoma
-
Muller S, Lindquist D, Kanter L, Flores-Staino C, Henriksson R, Hedman H & Andersson S 2013 Expression of LRIG1 and LRIG3 correlates with human papillomavirus status and patient survival in cervical adenocarcinoma. International Journal of Oncology 42 247-252. (doi:10.3892/ijo.2012.1702)
-
(2013)
International Journal of Oncology
, vol.42
, pp. 247-252
-
-
Muller, S.1
Lindquist, D.2
Kanter, L.3
Flores-Staino, C.4
Henriksson, R.5
Hedman, H.6
Andersson, S.7
-
43
-
-
84899453808
-
LRIG1 as a potential novel marker for neoplastic transformation in ocular surface squamous neoplasia
-
NagataM, Nakamura T, Sotozono C, Inatomi T, Yokoi N& Kinoshita S 2014 LRIG1 as a potential novel marker for neoplastic transformation in ocular surface squamous neoplasia. PLoS ONE 9 e93164. (doi:10.1371/journal.pone.0093164)
-
(2014)
PLoS ONE
, vol.9
, pp. e93164
-
-
Nagatam Nakamura, T.1
Sotozono, C.2
Inatomi, T.3
Yokoi, N.4
Kinoshita, S.5
-
44
-
-
84892944262
-
LRIG1 inhibits STAT3-dependent inflammation to maintain corneal homeostasis
-
Nakamura T, Hamuro J, Takaishi M, Simmons S, Maruyama K, Zaffalon A, Bentley AJ, Kawasaki S, Nagata-Takaoka M, Fullwood NJ et al. 2014 LRIG1 inhibits STAT3-dependent inflammation to maintain corneal homeostasis. Journal of Clinical Investigation 124 385-397. (doi:10.1172/JCI71488)
-
(2014)
Journal of Clinical Investigation
, vol.124
, pp. 385-397
-
-
Nakamura, T.1
Hamuro, J.2
Takaishi, M.3
Simmons, S.4
Maruyama, K.5
Zaffalon, A.6
Bentley, A.J.7
Kawasaki, S.8
Nagata-Takaoka, M.9
Fullwood, N.J.10
-
45
-
-
0034810996
-
Cloning, characterization, and expression of human LIG1
-
Nilsson J, Vallbo C, Guo D, Golovleva I, Hallberg B, Henriksson R & Hedman H 2001 Cloning, characterization, and expression of human LIG1. Biochemical and Biophysical Research Communications 284 1155-1161. (doi:10.1006/bbrc.2001.5092)
-
(2001)
Biochemical and Biophysical Research Communications
, vol.284
, pp. 1155-1161
-
-
Nilsson, J.1
Vallbo, C.2
Guo, D.3
Golovleva, I.4
Hallberg, B.5
Henriksson, R.6
Hedman, H.7
-
46
-
-
84900992899
-
USP8 modulates ubiquitination of LRIG1 for Met degradation
-
Oh YM, Lee SB, Choi J, Suh HY, Shim S, Song YJ, Kim B, Lee JM, Oh SJ, Jeong Y et al. 2014 USP8 modulates ubiquitination of LRIG1 for Met degradation. Scientific Reports 4 4980. (doi:10.1038/srep04980)
-
(2014)
Scientific Reports
, vol.4
, pp. 4980
-
-
Oh, Y.M.1
Lee, S.B.2
Choi, J.3
Suh, H.Y.4
Shim, S.5
Song, Y.J.6
Kim, B.7
Lee, J.M.8
Oh, S.J.9
Jeong, Y.10
-
47
-
-
84885184673
-
The epidermis comprises autonomous compartments maintained by distinct stem cell populations
-
Page ME, Lombard P, Ng F, Gottgens B & Jensen KB 2013 The epidermis comprises autonomous compartments maintained by distinct stem cell populations. Cell Stem Cell 13 471-482. (doi:10.1016/j.stem.2013.07.010)
-
(2013)
Cell Stem Cell
, vol.13
, pp. 471-482
-
-
Page, M.E.1
Lombard, P.2
Ng, F.3
Gottgens, B.4
Jensen, K.B.5
-
48
-
-
77953229417
-
Loss-of-function mutations in HPSE2 cause the autosomal recessive urofacial syndrome
-
Pang J, Zhang S, Yang P, Hawkins-Lee B, Zhong J, Zhang Y, Ochoa B, Agundez JA, Voelckel MA, Fisher RB et al. 2010 Loss-of-function mutations in HPSE2 cause the autosomal recessive urofacial syndrome. American Journal of Human Genetics 86 957-962. (doi:10.1016/j.ajhg.2010.04.016)
-
(2010)
American Journal of Human Genetics
, vol.86
, pp. 957-962
-
-
Pang, J.1
Zhang, S.2
Yang, P.3
Hawkins-Lee, B.4
Zhong, J.5
Zhang, Y.6
Ochoa, B.7
Agundez, J.A.8
Voelckel, M.A.9
Fisher, R.B.10
-
49
-
-
0035930341
-
Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein
-
Peschard P, Fournier TM, Lamorte L, Naujokas MA, Band H, Langdon WY & ParkM2001 Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein. Molecular Cell 8 995-1004. (doi:10.1016/S1097-2765(01)00378-1)
-
(2001)
Molecular Cell
, vol.8
, pp. 995-1004
-
-
Peschard, P.1
Fournier, T.M.2
Lamorte, L.3
Naujokas, M.A.4
Band, H.5
Langdon, W.Y.6
Park, M.7
-
50
-
-
84859196824
-
The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor
-
Powell AE, Wang Y, Li Y, Poulin EJ, Means AL, Washington MK, Higginbotham JN, Juchheim A, Prasad N, Levy SE et al. 2012 The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor. Cell 149 146-158. (doi:10.1016/j.cell.2012.02.042)
-
(2012)
Cell
, vol.149
, pp. 146-158
-
-
Powell, A.E.1
Wang, Y.2
Li, Y.3
Poulin, E.J.4
Means, A.L.5
Washington, M.K.6
Higginbotham, J.N.7
Juchheim, A.8
Prasad, N.9
Levy, S.E.10
-
51
-
-
84903584602
-
Inducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis
-
Powell AE, Vlacich G, Zhao ZY, McKinley ET, Washington MK, Manning HC & Coffey RJ 2014 Inducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis. American Journal of Physiology. Gastrointestinal and Liver Physiology 307 G16-G23. (doi:10.1152/ajpgi. 00358.2013)
-
(2014)
American Journal of Physiology. Gastrointestinal and Liver Physiology
, vol.307
, pp. G16-G23
-
-
Powell, A.E.1
Vlacich, G.2
Zhao, Z.Y.3
McKinley, E.T.4
Washington, M.K.5
Manning, H.C.6
Coffey, R.J.7
-
52
-
-
84881542417
-
LRIG1 dictates the chemo-sensitivity of temozolomide (TMZ) in U251 glioblastoma cells via down-regulation of EGFR/topoisomerase-2/Bcl-2
-
Qi XC, Xie DJ, Yan QF, Wang YR, Zhu YX, Qian C & Yang SX 2013 LRIG1 dictates the chemo-sensitivity of temozolomide (TMZ) in U251 glioblastoma cells via down-regulation of EGFR/topoisomerase-2/Bcl-2. Biochemical and Biophysical Research Communications 437 565-572. (doi:10.1016/j.bbrc.2013.06.116)
-
(2013)
Biochemical and Biophysical Research Communications
, vol.437
, pp. 565-572
-
-
Qi, X.C.1
Xie, D.J.2
Yan, Q.F.3
Wang, Y.R.4
Zhu, Y.X.5
Qian, C.6
Yang, S.X.7
-
53
-
-
2442552774
-
E-cadherinmediated adhesion inhibits ligand-dependent activation of diverse receptor tyrosine kinases
-
Qian X, Karpova T, Sheppard AM, McNally J & Lowy DR 2004 E-cadherinmediated adhesion inhibits ligand-dependent activation of diverse receptor tyrosine kinases. EMBO Journal 23 1739-1748. (doi:10.1038/sj.emboj.7600136)
-
(2004)
EMBO Journal
, vol.23
, pp. 1739-1748
-
-
Qian, X.1
Karpova, T.2
Sheppard, A.M.3
McNally, J.4
Lowy, D.R.5
-
54
-
-
84881246735
-
Leucine-rich repeat and immunoglobulin domaincontaining protein-1 (Lrig1) negative regulatory action toward ErbB receptor tyrosine kinases is opposed by leucine-rich repeat and immunoglobulin domain-containing protein 3 (Lrig3)
-
Rafidi H, Mercado F III, Astudillo M, Fry WH, Saldana M, Carraway KL III & Sweeney C 2013 Leucine-rich repeat and immunoglobulin domaincontaining protein-1 (Lrig1) negative regulatory action toward ErbB receptor tyrosine kinases is opposed by leucine-rich repeat and immunoglobulin domain-containing protein 3 (Lrig3). Journal of Biological Chemistry 288 21593-21605. (doi:10.1074/jbc.M113.486050)
-
(2013)
Journal of Biological Chemistry
, vol.288
, pp. 21593-21605
-
-
Rafidi, H.1
Mercado, F.2
Astudillo, M.3
Fry, W.H.4
Saldana, M.5
Carraway, K.L.6
Sweeney, C.7
-
55
-
-
0029800810
-
Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets
-
Reifenberger G, Ichimura K, Reifenberger J, Elkahloun AG, Meltzer PS & Collins VP 1996 Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets. Cancer Research 56 5141-5145.
-
(1996)
Cancer Research
, vol.56
, pp. 5141-5145
-
-
Reifenberger, G.1
Ichimura, K.2
Reifenberger, J.3
Elkahloun, A.G.4
Meltzer, P.S.5
Collins, V.P.6
-
56
-
-
80053189298
-
Predicting the functional impact of protein mutations: Application to cancer genomics
-
Reva B, Antipin Y & Sander C 2011 Predicting the functional impact of protein mutations: application to cancer genomics. Nucleic Acids Research 39 e118. (doi:10.1093/nar/gkr407)
-
(2011)
Nucleic Acids Research
, vol.39
, pp. e118
-
-
Reva, B.1
Antipin, Y.2
Sander, C.3
-
57
-
-
84904750832
-
Heparanase 2, mutated in urofacial syndrome, mediates peripheral neural development in Xenopus
-
Roberts NA, Woolf AS, Stuart HM, Thuret R, McKenzie EA, NewmanWG & Hilton EN 2014 Heparanase 2, mutated in urofacial syndrome, mediates peripheral neural development in Xenopus. Human Molecular Genetics 23 4302-4314. (doi:10.1093/hmg/ddu147)
-
(2014)
Human Molecular Genetics
, vol.23
, pp. 4302-4314
-
-
Roberts, N.A.1
Woolf, A.S.2
Stuart, H.M.3
Thuret, R.4
McKenzie, E.A.5
Hilton, E.N.6
-
58
-
-
84883381112
-
Lrig2-deficient mice are protected against PDGFBinduced glioma
-
Rondahl V, Holmlund C, Karlsson T, Wang B, Faraz M, Henriksson R & Hedman H 2013 Lrig2-deficient mice are protected against PDGFBinduced glioma. PLoS ONE 8 e73635. (doi:10.1371/journal.pone. 0073635)
-
(2013)
PLoS ONE
, vol.8
, pp. e73635
-
-
Rondahl, V.1
Holmlund, C.2
Karlsson, T.3
Wang, B.4
Faraz, M.5
Henriksson, R.6
Hedman, H.7
-
59
-
-
77952318977
-
Identifying common prognostic factors in genomic cancer studies: A novel index for censored outcomes
-
Rouam S, Moreau T & Broet P 2010 Identifying common prognostic factors in genomic cancer studies: a novel index for censored outcomes. BMC Bioinformatics 11 150. (doi:10.1186/1471-2105-11-150)
-
(2010)
BMC Bioinformatics
, vol.11
, pp. 150
-
-
Rouam, S.1
Moreau, T.2
Broet, P.3
-
61
-
-
33847181657
-
LRIG1 is a novel negative regulator of the Met receptor and opposes Met and Her2 synergy
-
Shattuck DL, Miller JK, Laederich M, Funes M, Petersen H, Carraway KL III & Sweeney C 2007 LRIG1 is a novel negative regulator of the Met receptor and opposes Met and Her2 synergy. Molecular and Cellular Biology 27 1934-1946. (doi:10.1128/MCB.00757-06)
-
(2007)
Molecular and Cellular Biology
, vol.27
, pp. 1934-1946
-
-
Shattuck, D.L.1
Miller, J.K.2
Laederich, M.3
Funes, M.4
Petersen, H.5
Carraway, K.L.6
Sweeney, C.7
-
62
-
-
84896405445
-
LRIG1 modulates aggressiveness of head and neck cancers by regulating EGFR-MAPK-SPHK1 signaling and extracellular matrix remodeling
-
Sheu JJ, Lee CC, Hua CH, Li CI, Lai MT, Lee SC, Cheng J, Chen CM, Chan C, Chao SC et al. 2014 LRIG1 modulates aggressiveness of head and neck cancers by regulating EGFR-MAPK-SPHK1 signaling and extracellular matrix remodeling. Oncogene 33 1375-1384. (doi:10.1038/onc.2013.98)
-
(2014)
Oncogene
, vol.33
, pp. 1375-1384
-
-
Sheu, J.J.1
Lee, C.C.2
Hua, C.H.3
Li, C.I.4
Lai, M.T.5
Lee, S.C.6
Cheng, J.7
Chen, C.M.8
Chan, C.9
Chao, S.C.10
-
63
-
-
84893302245
-
Epidermal growth factor receptor mutations in lung adenocarcinoma
-
Siegelin MD & Borczuk AC 2014 Epidermal growth factor receptor mutations in lung adenocarcinoma. Laboratory Investigation 94 129-137. (doi:10.1038/labinvest.2013.147)
-
(2014)
Laboratory Investigation
, vol.94
, pp. 129-137
-
-
Siegelin, M.D.1
Borczuk, A.C.2
-
64
-
-
84873735633
-
LRIG2 mutations cause urofacial syndrome
-
Stuart HM, Roberts NA, Burgu B, Daly SB, Urquhart JE, Bhaskar S, Dickerson JE, Mermerkaya M, Silay MS, Lewis MA et al. 2013 LRIG2 mutations cause urofacial syndrome. American Journal of Human Genetics 92 259-264. (doi:10.1016/j.ajhg.2012.12.002)
-
(2013)
American Journal of Human Genetics
, vol.92
, pp. 259-264
-
-
Stuart, H.M.1
Roberts, N.A.2
Burgu, B.3
Daly, S.B.4
Urquhart, J.E.5
Bhaskar, S.6
Dickerson, J.E.7
Mermerkaya, M.8
Silay, M.S.9
Lewis, M.A.10
-
65
-
-
52949087545
-
LRIG1 negatively regulates the oncogenic EGF receptor mutant EGFRvIII
-
Stutz MA, Shattuck DL, Laederich MB, Carraway KL III & Sweeney C 2008 LRIG1 negatively regulates the oncogenic EGF receptor mutant EGFRvIII. Oncogene 27 5741-5752. (doi:10.1038/onc.2008.185)
-
(2008)
Oncogene
, vol.27
, pp. 5741-5752
-
-
Stutz, M.A.1
Shattuck, D.L.2
Laederich, M.B.3
Carraway, K.L.4
Sweeney, C.5
-
66
-
-
0029829132
-
CDNA cloning of a novel membrane glycoprotein that is expressed specifically in glial cells in the mouse brain. LIG-1, a protein with leucine-rich repeats and immunoglobulin-like domains
-
Suzuki Y, Sato N, Tohyama M, Wanaka A & Takagi T 1996 cDNA cloning of a novel membrane glycoprotein that is expressed specifically in glial cells in the mouse brain. LIG-1, a protein with leucine-rich repeats and immunoglobulin-like domains. Journal of Biological Chemistry 271 22522-22527. (doi:10.1074/jbc.271.37.22522)
-
(1996)
Journal of Biological Chemistry
, vol.271
, pp. 22522-22527
-
-
Suzuki, Y.1
Sato, N.2
Tohyama, M.3
Wanaka, A.4
Takagi, T.5
-
67
-
-
18444370552
-
Targeted disruption of LIG-1 gene results in psoriasiform epidermal hyperplasia
-
Suzuki Y, Miura H, Tanemura A, Kobayashi K, Kondoh G, Sano S, Ozawa K, Inui S, Nakata A, Takagi T et al. 2002 Targeted disruption of LIG-1 gene results in psoriasiform epidermal hyperplasia. FEBS Letters 521 67-71. (doi:10.1016/S0014-5793(02)02824-7)
-
(2002)
FEBS Letters
, vol.521
, pp. 67-71
-
-
Suzuki, Y.1
Miura, H.2
Tanemura, A.3
Kobayashi, K.4
Kondoh, G.5
Sano, S.6
Ozawa, K.7
Inui, S.8
Nakata, A.9
Takagi, T.10
-
68
-
-
16844364208
-
LRIG-1 provides a novel prognostic predictor in squamous cell carcinoma of the skin: Immunohistochemical analysis for 38 cases
-
Tanemura A, Nagasawa T, Inui S & Itami S 2005 LRIG-1 provides a novel prognostic predictor in squamous cell carcinoma of the skin: immunohistochemical analysis for 38 cases. Dermatologic Surgery 31 423-430. (doi:10.1097/00042728-200504000-00008)
-
(2005)
Dermatologic Surgery
, vol.31
, pp. 423-430
-
-
Tanemura, A.1
Nagasawa, T.2
Inui, S.3
Itami, S.4
-
69
-
-
79955477797
-
LRIG1 and the liar paradox in prostate cancer: A study of the expression and clinical significance of LRIG1 in prostate cancer
-
ThomassonM,Wang B, Hammarsten P, Dahlman A, Persson JL, Josefsson A, Stattin P, Granfors T, Egevad L, Henriksson R et al. 2011 LRIG1 and the liar paradox in prostate cancer: a study of the expression and clinical significance of LRIG1 in prostate cancer. International Journal of Cancer 128 2843-2852. (doi:10.1002/ijc.25820)
-
(2011)
International Journal of Cancer
, vol.128
, pp. 2843-2852
-
-
Thomassonmwang, B.1
Hammarsten, P.2
Dahlman, A.3
Persson, J.L.4
Josefsson, A.5
Stattin, P.6
Granfors, T.7
Egevad, L.8
Henriksson, R.9
-
70
-
-
84860374309
-
Gene expression pattern of the epidermal growth factor receptor family and LRIG1 in renal cell carcinoma
-
Thomasson M, Hedman H, Ljungberg B & Henriksson R 2012 Gene expression pattern of the epidermal growth factor receptor family and LRIG1 in renal cell carcinoma. BMC Research Notes 5 216. (doi:10.1186/ 1756-0500-5-216)
-
(2012)
BMC Research Notes
, vol.5
, Issue.216
, pp. 5-216
-
-
Thomasson, M.1
Hedman, H.2
Ljungberg, B.3
Henriksson, R.4
-
71
-
-
84902175780
-
Loss of LRIG1 locus increases risk of early and late relapse of stage I/II breast cancer
-
Thompson PA, Ljuslinder I, Tsavachidis S, Brewster A, Sahin A, Hedman H, Henriksson R, Bondy ML &Melin BS 2014 Loss of LRIG1 locus increases risk of early and late relapse of stage I/II breast cancer. Cancer Research 74 2928-2935. (doi:10.1158/0008-5472.CAN-13-2112)
-
(2014)
Cancer Research
, vol.74
, pp. 2928-2935
-
-
Thompson, P.A.1
Ljuslinder, I.2
Tsavachidis, S.3
Brewster, A.4
Sahin, A.5
Hedman, H.6
Henriksson, R.7
Bondy, M.L.8
Melin, B.S.9
-
72
-
-
68049137882
-
Down regulation of LRIG2 expression by RNA interference inhibits glioblastoma cell (GL15) growth, causes cell cycle redistribution, increases cell apoptosis and enhances cell adhesion and invasion in vitro
-
Wang B, Han L, Chen R, Cai M, Han F, Lei T & Guo D 2009 Down regulation of LRIG2 expression by RNA interference inhibits glioblastoma cell (GL15) growth, causes cell cycle redistribution, increases cell apoptosis and enhances cell adhesion and invasion in vitro. Cancer Biology & Therapy 8 1018-1023. (doi:10.4161/cbt.8.11.8375)
-
(2009)
Cancer Biology & Therapy
, vol.8
, pp. 1018-1023
-
-
Wang, B.1
Han, L.2
Chen, R.3
Cai, M.4
Han, F.5
Lei, T.6
Guo, D.7
-
73
-
-
84875581550
-
LRIG1 enhances cisplatin sensitivity of glioma cell lines
-
Wang X, Xiao Q, Xing X, Tian C, Zhang H, Ye F, Wan F,Wang B, Guo D & Lei T 2012 LRIG1 enhances cisplatin sensitivity of glioma cell lines. Oncology Research 20 205-211. (doi:10.3727/096504013X13589503482770)
-
(2012)
Oncology Research
, vol.20
, pp. 205-211
-
-
Wang, X.1
Xiao, Q.2
Xing, X.3
Tian, C.4
Zhang, H.5
Ye, F.6
Wan Fwang, B.7
Guo, D.8
Lei, T.9
-
74
-
-
84878598705
-
LRIG1 is a triple threat: ERBB negative regulator, intestinal stem cell marker and tumour suppressor
-
Wang Y, Poulin EJ & Coffey RJ 2013 LRIG1 is a triple threat: ERBB negative regulator, intestinal stem cell marker and tumour suppressor. British Journal of Cancer 108 1765-1770. (doi:10.1038/bjc.2013.138)
-
(2013)
British Journal of Cancer
, vol.108
, pp. 1765-1770
-
-
Wang, Y.1
Poulin, E.J.2
Coffey, R.J.3
-
75
-
-
84902343909
-
LRIG2 expression and prognosis in non-small cell lung cancer
-
Wang G, WuJ &Song H 2014 LRIG2 expression and prognosis in non-small cell lung cancer. Oncology Letters 8 667-672. (doi:10.3892/ol.2014. 2157)
-
(2014)
Oncology Letters
, vol.8
, pp. 667-672
-
-
Wang, G.1
Wu, J.2
Song, H.3
-
76
-
-
84859430024
-
Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling
-
Wong VW, Stange DE, Page ME, Buczacki S, Wabik A, Itami S, van de Wetering M, Poulsom R, Wright NA, Trotter MW et al. 2012 Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling. Nature Cell Biology 14 401-408. (doi:10.1038/ncb2464)
-
(2012)
Nature Cell Biology
, vol.14
, pp. 401-408
-
-
Wong, V.W.1
Stange, D.E.2
Page, M.E.3
Buczacki, S.4
Wabik, A.5
Itami, S.6
Van De Wetering, M.7
Poulsom, R.8
Wright, N.A.9
Trotter, M.W.10
-
77
-
-
84872840197
-
Downregulation of LRIG1 expression by RNA interference promotes the aggressive properties of glioma cells via EGFR/Akt/c-Myc activation
-
Xie R, Yang H, Xiao Q, Mao F, Zhang S, Ye F, Wan F,Wang B, Lei T & Guo D 2013 Downregulation of LRIG1 expression by RNA interference promotes the aggressive properties of glioma cells via EGFR/Akt/c-Myc activation. Oncology Reports 29 177-184. (doi:10.3892/or.2012.2102)
-
(2013)
Oncology Reports
, vol.29
, pp. 177-184
-
-
Xie, R.1
Yang, H.2
Xiao, Q.3
Mao, F.4
Zhang, S.5
Ye, F.6
Wan Fwang, B.7
Lei, T.8
Guo, D.9
-
78
-
-
68949144565
-
Upregulation of LRIG1 suppresses malignant glioma cell growth by attenuating EGFR activity
-
Ye F, Gao Q, Xu T, Zeng L, Ou Y, Mao F, Wang H, He Y, Wang B, Yang Z et al. 2009 Upregulation of LRIG1 suppresses malignant glioma cell growth by attenuating EGFR activity. Journal of Neuro-Oncology 94 183-194. (doi:10.1007/s11060-009-9836-1)
-
(2009)
Journal of Neuro-Oncology
, vol.94
, pp. 183-194
-
-
Ye, F.1
Gao, Q.2
Xu, T.3
Zeng, L.4
Ou, Y.5
Mao, F.6
Wang, H.7
He, Y.8
Wang, B.9
Yang, Z.10
-
79
-
-
78651424398
-
Paracrine regulation of growth factor signaling by shed leucinerich repeats and immunoglobulin-like domains 1
-
Yi W, Holmlund C, Nilsson J, Inui S, Lei T, Itami S, Henriksson R & Hedman H 2011 Paracrine regulation of growth factor signaling by shed leucinerich repeats and immunoglobulin-like domains 1. Experimental Cell Research 317 504-512. (doi:10.1016/j.yexcr.2010.11.005)
-
(2011)
Experimental Cell Research
, vol.317
, pp. 504-512
-
-
Yi, W.1
Holmlund, C.2
Nilsson, J.3
Inui, S.4
Lei, T.5
Itami, S.6
Henriksson, R.7
Hedman, H.8
-
80
-
-
43049116136
-
Lrig3 regulates neural crest formation in Xenopus by modulating Fgf and Wnt signaling pathways
-
Zhao H, Tanegashima K, Ro H & Dawid IB 2008 Lrig3 regulates neural crest formation in Xenopus by modulating Fgf and Wnt signaling pathways. Development 135 1283-1293. (doi:10.1242/dev.015073)
-
(2008)
Development
, vol.135
, pp. 1283-1293
-
-
Zhao, H.1
Tanegashima, K.2
Ro, H.3
Dawid, I.B.4
-
81
-
-
0141619346
-
Genome-wide identification of chromosomal regions of increased tumor expression by transcriptome analysis
-
Zhou Y, Luoh SM, Zhang Y, Watanabe C, Wu TD, Ostland M, Wood WI & Zhang Z 2003 Genome-wide identification of chromosomal regions of increased tumor expression by transcriptome analysis. Cancer Research 63 5781-5784.
-
(2003)
Cancer Research
, vol.63
, pp. 5781-5784
-
-
Zhou, Y.1
Luoh, S.M.2
Zhang, Y.3
Watanabe, C.4
Wu, T.D.5
Ostland, M.6
Wood, W.I.7
Zhang, Z.8
|