메뉴 건너뛰기




Volumn 14, Issue 2, 2016, Pages 269-281

Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CELL PROTEIN; DIPEPTIDYL PEPTIDASE IV; HERMES ANTIGEN; PROTEIN LGR1; PROTEIN LGR5; PROTEIN LGR6; UNCLASSIFIED DRUG;

EID: 84955415508     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.12.041     Document Type: Article
Times cited : (55)

References (68)
  • 2
    • 84857570226 scopus 로고    scopus 로고
    • Epithelial stem cells, wound healing and cancer
    • Arwert E.N., Hoste E., Watt F.M. Epithelial stem cells, wound healing and cancer. Nat. Rev. Cancer 2012, 12:170-180.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 170-180
    • Arwert, E.N.1    Hoste, E.2    Watt, F.M.3
  • 3
    • 84857368462 scopus 로고    scopus 로고
    • Upregulation of CD26 expression in epithelial cells and stromal cells during wound-induced skin tumour formation
    • Arwert E.N., Mentink R.A., Driskell R.R., Hoste E., Goldie S.J., Quist S., Watt F.M. Upregulation of CD26 expression in epithelial cells and stromal cells during wound-induced skin tumour formation. Oncogene 2012, 31:992-1000.
    • (2012) Oncogene , vol.31 , pp. 992-1000
    • Arwert, E.N.1    Mentink, R.A.2    Driskell, R.R.3    Hoste, E.4    Goldie, S.J.5    Quist, S.6    Watt, F.M.7
  • 4
    • 77953697794 scopus 로고    scopus 로고
    • Differential sensitivity of epidermal cell subpopulations to beta-catenin-induced ectopic hair follicle formation
    • Baker C.M., Verstuyf A., Jensen K.B., Watt F.M. Differential sensitivity of epidermal cell subpopulations to beta-catenin-induced ectopic hair follicle formation. Dev. Biol. 2010, 343:40-50.
    • (2010) Dev. Biol. , vol.343 , pp. 40-50
    • Baker, C.M.1    Verstuyf, A.2    Jensen, K.B.3    Watt, F.M.4
  • 8
    • 4444290010 scopus 로고    scopus 로고
    • Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche
    • Blanpain C., Lowry W.E., Geoghegan A., Polak L., Fuchs E. Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell 2004, 118:635-648.
    • (2004) Cell , vol.118 , pp. 635-648
    • Blanpain, C.1    Lowry, W.E.2    Geoghegan, A.3    Polak, L.4    Fuchs, E.5
  • 9
    • 33846705750 scopus 로고    scopus 로고
    • Epithelial stem cells: turning over new leaves
    • Blanpain C., Horsley V., Fuchs E. Epithelial stem cells: turning over new leaves. Cell 2007, 128:445-458.
    • (2007) Cell , vol.128 , pp. 445-458
    • Blanpain, C.1    Horsley, V.2    Fuchs, E.3
  • 10
    • 0242460440 scopus 로고    scopus 로고
    • Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in wholemounts of mouse epidermis
    • Braun K.M., Niemann C., Jensen U.B., Sundberg J.P., Silva-Vargas V., Watt F.M. Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in wholemounts of mouse epidermis. Development 2003, 130:5241-5255.
    • (2003) Development , vol.130 , pp. 5241-5255
    • Braun, K.M.1    Niemann, C.2    Jensen, U.B.3    Sundberg, J.P.4    Silva-Vargas, V.5    Watt, F.M.6
  • 11
    • 79955699992 scopus 로고    scopus 로고
    • Nerve-derived sonic hedgehog defines a niche for hair follicle stem cells capable of becoming epidermal stem cells
    • Brownell I., Guevara E., Bai C.B., Loomis C.A., Joyner A.L. Nerve-derived sonic hedgehog defines a niche for hair follicle stem cells capable of becoming epidermal stem cells. Cell Stem Cell 2011, 8:552-565.
    • (2011) Cell Stem Cell , vol.8 , pp. 552-565
    • Brownell, I.1    Guevara, E.2    Bai, C.B.3    Loomis, C.A.4    Joyner, A.L.5
  • 12
    • 0035570374 scopus 로고    scopus 로고
    • Dermatofibroma (fibrous histiocytoma): an inflammatory or neoplastic disorder?
    • Calonje E. Dermatofibroma (fibrous histiocytoma): an inflammatory or neoplastic disorder?. Histopathology 2001, 39:213.
    • (2001) Histopathology , vol.39 , pp. 213
    • Calonje, E.1
  • 13
    • 0032953231 scopus 로고    scopus 로고
    • A common human skin tumour is caused by activating mutations in beta-catenin
    • Chan E.F., Gat U., McNiff J.M., Fuchs E. A common human skin tumour is caused by activating mutations in beta-catenin. Nat. Genet. 1999, 21:410-413.
    • (1999) Nat. Genet. , vol.21 , pp. 410-413
    • Chan, E.F.1    Gat, U.2    McNiff, J.M.3    Fuchs, E.4
  • 14
    • 0033970927 scopus 로고    scopus 로고
    • Dermatofibroma is a clonal proliferative disease
    • Chen T.C., Kuo T., Chan H.L. Dermatofibroma is a clonal proliferative disease. J. Cutan. Pathol. 2000, 27:36-39.
    • (2000) J. Cutan. Pathol. , vol.27 , pp. 36-39
    • Chen, T.C.1    Kuo, T.2    Chan, H.L.3
  • 16
    • 84890076086 scopus 로고    scopus 로고
    • Distinct functions for Wnt/β-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis
    • Choi Y.S., Zhang Y., Xu M., Yang Y., Ito M., Peng T., Cui Z., Nagy A., Hadjantonakis A.K., Lang R.A., et al. Distinct functions for Wnt/β-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis. Cell Stem Cell 2013, 13:720-733.
    • (2013) Cell Stem Cell , vol.13 , pp. 720-733
    • Choi, Y.S.1    Zhang, Y.2    Xu, M.3    Yang, Y.4    Ito, M.5    Peng, T.6    Cui, Z.7    Nagy, A.8    Hadjantonakis, A.K.9    Lang, R.A.10
  • 17
    • 80755184835 scopus 로고    scopus 로고
    • Reprogramming adult dermis to a neonatal state through epidermal activation of β-catenin
    • Collins C.A., Kretzschmar K., Watt F.M. Reprogramming adult dermis to a neonatal state through epidermal activation of β-catenin. Development 2011, 138:5189-5199.
    • (2011) Development , vol.138 , pp. 5189-5199
    • Collins, C.A.1    Kretzschmar, K.2    Watt, F.M.3
  • 18
    • 84896988913 scopus 로고    scopus 로고
    • β-Catenin activation regulates tissue growth non-cell autonomously in the hair stem cell niche
    • Deschene E.R., Myung P., Rompolas P., Zito G., Sun T.Y., Taketo M.M., Saotome I., Greco V. β-Catenin activation regulates tissue growth non-cell autonomously in the hair stem cell niche. Science 2014, 343:1353-1356.
    • (2014) Science , vol.343 , pp. 1353-1356
    • Deschene, E.R.1    Myung, P.2    Rompolas, P.3    Zito, G.4    Sun, T.Y.5    Taketo, M.M.6    Saotome, I.7    Greco, V.8
  • 21
    • 22844437793 scopus 로고    scopus 로고
    • Tumour regulation of fibroblast hyaluronan expression: a mechanism to facilitate tumour growth and invasion
    • Edward M., Gillan C., Micha D., Tammi R.H. Tumour regulation of fibroblast hyaluronan expression: a mechanism to facilitate tumour growth and invasion. Carcinogenesis 2005, 26:1215-1223.
    • (2005) Carcinogenesis , vol.26 , pp. 1215-1223
    • Edward, M.1    Gillan, C.2    Micha, D.3    Tammi, R.H.4
  • 23
    • 0032567078 scopus 로고    scopus 로고
    • De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin
    • Gat U., DasGupta R., Degenstein L., Fuchs E. De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin. Cell 1998, 95:605-614.
    • (1998) Cell , vol.95 , pp. 605-614
    • Gat, U.1    DasGupta, R.2    Degenstein, L.3    Fuchs, E.4
  • 24
    • 84881457432 scopus 로고    scopus 로고
    • The interfollicular epidermis of adult mouse tail comprises two distinct cell lineages that are differentially regulated by Wnt, Edaradd, and Lrig1
    • Gomez C., Chua W., Miremadi A., Quist S., Headon D.J., Watt F.M. The interfollicular epidermis of adult mouse tail comprises two distinct cell lineages that are differentially regulated by Wnt, Edaradd, and Lrig1. Stem Cell Reports 2013, 1:19-27.
    • (2013) Stem Cell Reports , vol.1 , pp. 19-27
    • Gomez, C.1    Chua, W.2    Miremadi, A.3    Quist, S.4    Headon, D.J.5    Watt, F.M.6
  • 26
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 27
    • 0033230616 scopus 로고    scopus 로고
    • Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene
    • Harada N., Tamai Y., Ishikawa T., Sauer B., Takaku K., Oshima M., Taketo M.M. Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene. EMBO J. 1999, 18:5931-5942.
    • (1999) EMBO J. , vol.18 , pp. 5931-5942
    • Harada, N.1    Tamai, Y.2    Ishikawa, T.3    Sauer, B.4    Takaku, K.5    Oshima, M.6    Taketo, M.M.7
  • 28
    • 0035907041 scopus 로고    scopus 로고
    • Beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin
    • Huelsken J., Vogel R., Erdmann B., Cotsarelis G., Birchmeier W. beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell 2001, 105:533-545.
    • (2001) Cell , vol.105 , pp. 533-545
    • Huelsken, J.1    Vogel, R.2    Erdmann, B.3    Cotsarelis, G.4    Birchmeier, W.5
  • 31
    • 77953859606 scopus 로고    scopus 로고
    • NF-kappaB as a critical link between inflammation and cancer
    • Karin M. NF-kappaB as a critical link between inflammation and cancer. Cold Spring Harb. Perspect. Biol. 2009, 1:a000141.
    • (2009) Cold Spring Harb. Perspect. Biol. , vol.1 , pp. a000141
    • Karin, M.1
  • 32
    • 42549164807 scopus 로고    scopus 로고
    • Wnt signalling and its impact on development and cancer
    • Klaus A., Birchmeier W. Wnt signalling and its impact on development and cancer. Nat. Rev. Cancer 2008, 8:387-398.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 387-398
    • Klaus, A.1    Birchmeier, W.2
  • 33
    • 84856090845 scopus 로고    scopus 로고
    • Lineage tracing
    • Kretzschmar K., Watt F.M. Lineage tracing. Cell 2012, 148:33-45.
    • (2012) Cell , vol.148 , pp. 33-45
    • Kretzschmar, K.1    Watt, F.M.2
  • 34
    • 84908019448 scopus 로고    scopus 로고
    • Markers of epidermal stem cell subpopulations in adult mammalian skin
    • Kretzschmar K., Watt F.M. Markers of epidermal stem cell subpopulations in adult mammalian skin. Cold Spring Harb. Perspect. Med. 2014, 4:a013631.
    • (2014) Cold Spring Harb. Perspect. Med. , vol.4 , pp. a013631
    • Kretzschmar, K.1    Watt, F.M.2
  • 35
    • 84947027848 scopus 로고    scopus 로고
    • The androgen receptor antagonizes Wnt/β-catenin signaling in epidermal stem cells
    • Kretzschmar K., Cottle D.L., Schweiger P.J., Watt F.M. The androgen receptor antagonizes Wnt/β-catenin signaling in epidermal stem cells. J. Invest. Dermatol. 2015, 135:2753-2763.
    • (2015) J. Invest. Dermatol. , vol.135 , pp. 2753-2763
    • Kretzschmar, K.1    Cottle, D.L.2    Schweiger, P.J.3    Watt, F.M.4
  • 36
    • 27544448665 scopus 로고    scopus 로고
    • Trichoadenoma: cytokeratin expression suggesting differentiation towards the follicular infundibulum and follicular bulge regions
    • Kurokawa I., Mizutani H., Nishijima S., Kato N., Yasui K., Tsubura A. Trichoadenoma: cytokeratin expression suggesting differentiation towards the follicular infundibulum and follicular bulge regions. Br. J. Dermatol. 2005, 153:1084-1086.
    • (2005) Br. J. Dermatol. , vol.153 , pp. 1084-1086
    • Kurokawa, I.1    Mizutani, H.2    Nishijima, S.3    Kato, N.4    Yasui, K.5    Tsubura, A.6
  • 38
    • 84897742831 scopus 로고    scopus 로고
    • Epidermal expression of Lgr6 is dependent on nerve endings and Schwann cells
    • Liao X.H., Nguyen H. Epidermal expression of Lgr6 is dependent on nerve endings and Schwann cells. Exp. Dermatol. 2014, 23:195-198.
    • (2014) Exp. Dermatol. , vol.23 , pp. 195-198
    • Liao, X.H.1    Nguyen, H.2
  • 39
    • 84875153351 scopus 로고    scopus 로고
    • Wnt signaling in skin development, homeostasis, and disease
    • Lim X., Nusse R. Wnt signaling in skin development, homeostasis, and disease. Cold Spring Harb. Perspect. Biol. 2013, 5:a008029.
    • (2013) Cold Spring Harb. Perspect. Biol. , vol.5 , pp. a008029
    • Lim, X.1    Nusse, R.2
  • 41
    • 2342427631 scopus 로고    scopus 로고
    • Transient activation of beta-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours
    • Lo Celso C., Prowse D.M., Watt F.M. Transient activation of beta-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours. Development 2004, 131:1787-1799.
    • (2004) Development , vol.131 , pp. 1787-1799
    • Lo Celso, C.1    Prowse, D.M.2    Watt, F.M.3
  • 42
    • 22344441322 scopus 로고    scopus 로고
    • Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells
    • Lowry W.E., Blanpain C., Nowak J.A., Guasch G., Lewis L., Fuchs E. Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells. Genes Dev. 2005, 19:1596-1611.
    • (2005) Genes Dev. , vol.19 , pp. 1596-1611
    • Lowry, W.E.1    Blanpain, C.2    Nowak, J.A.3    Guasch, G.4    Lewis, L.5    Fuchs, E.6
  • 45
    • 47549119127 scopus 로고    scopus 로고
    • A CK19(CreERT) knockin mouse line allows for conditional DNA recombination in epithelial cells in multiple endodermal organs
    • Means A.L., Xu Y., Zhao A., Ray K.C., Gu G. A CK19(CreERT) knockin mouse line allows for conditional DNA recombination in epithelial cells in multiple endodermal organs. Genesis 2008, 46:318-323.
    • (2008) Genesis , vol.46 , pp. 318-323
    • Means, A.L.1    Xu, Y.2    Zhao, A.3    Ray, K.C.4    Gu, G.5
  • 46
    • 0035395874 scopus 로고    scopus 로고
    • Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin
    • Merrill B.J., Gat U., DasGupta R., Fuchs E. Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin. Genes Dev. 2001, 15:1688-1705.
    • (2001) Genes Dev. , vol.15 , pp. 1688-1705
    • Merrill, B.J.1    Gat, U.2    DasGupta, R.3    Fuchs, E.4
  • 47
    • 0031908130 scopus 로고    scopus 로고
    • The structure and function of CD26 in the T-cell immune response
    • Morimoto C., Schlossman S.F. The structure and function of CD26 in the T-cell immune response. Immunol. Rev. 1998, 161:55-70.
    • (1998) Immunol. Rev. , vol.161 , pp. 55-70
    • Morimoto, C.1    Schlossman, S.F.2
  • 49
    • 0036023356 scopus 로고    scopus 로고
    • Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours
    • Niemann C., Owens D.M., Hülsken J., Birchmeier W., Watt F.M. Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours. Development 2002, 129:95-109.
    • (2002) Development , vol.129 , pp. 95-109
    • Niemann, C.1    Owens, D.M.2    Hülsken, J.3    Birchmeier, W.4    Watt, F.M.5
  • 50
    • 34248228314 scopus 로고    scopus 로고
    • Dual role of inactivating Lef1 mutations in epidermis: tumor promotion and specification of tumor type
    • Niemann C., Owens D.M., Schettina P., Watt F.M. Dual role of inactivating Lef1 mutations in epidermis: tumor promotion and specification of tumor type. Cancer Res. 2007, 67:2916-2921.
    • (2007) Cancer Res. , vol.67 , pp. 2916-2921
    • Niemann, C.1    Owens, D.M.2    Schettina, P.3    Watt, F.M.4
  • 52
    • 84885184673 scopus 로고    scopus 로고
    • The epidermis comprises autonomous compartments maintained by distinct stem cell populations
    • Page M.E., Lombard P., Ng F., Göttgens B., Jensen K.B. The epidermis comprises autonomous compartments maintained by distinct stem cell populations. Cell Stem Cell 2013, 13:471-482.
    • (2013) Cell Stem Cell , vol.13 , pp. 471-482
    • Page, M.E.1    Lombard, P.2    Ng, F.3    Göttgens, B.4    Jensen, K.B.5
  • 53
    • 44649160789 scopus 로고    scopus 로고
    • The vitamin D receptor is a Wnt effector that controls hair follicle differentiation and specifies tumor type in adult epidermis
    • Pálmer H.G., Anjos-Afonso F., Carmeliet G., Takeda H., Watt F.M. The vitamin D receptor is a Wnt effector that controls hair follicle differentiation and specifies tumor type in adult epidermis. PLoS ONE 2008, 3:e1483.
    • (2008) PLoS ONE , vol.3 , pp. e1483
    • Pálmer, H.G.1    Anjos-Afonso, F.2    Carmeliet, G.3    Takeda, H.4    Watt, F.M.5
  • 56
    • 73649140605 scopus 로고    scopus 로고
    • Trichoadenoma of Nikolowski is a distinct neoplasm within the spectrum of follicular tumors
    • Shimanovich I., Krahl D., Rose C. Trichoadenoma of Nikolowski is a distinct neoplasm within the spectrum of follicular tumors. J. Am. Acad. Dermatol. 2010, 62:277-283.
    • (2010) J. Am. Acad. Dermatol. , vol.62 , pp. 277-283
    • Shimanovich, I.1    Krahl, D.2    Rose, C.3
  • 57
    • 21344436821 scopus 로고    scopus 로고
    • Beta-catenin and Hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells
    • Silva-Vargas V., Lo Celso C., Giangreco A., Ofstad T., Prowse D.M., Braun K.M., Watt F.M. Beta-catenin and Hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells. Dev. Cell 2005, 9:121-131.
    • (2005) Dev. Cell , vol.9 , pp. 121-131
    • Silva-Vargas, V.1    Lo Celso, C.2    Giangreco, A.3    Ofstad, T.4    Prowse, D.M.5    Braun, K.M.6    Watt, F.M.7
  • 59
    • 84886283477 scopus 로고    scopus 로고
    • Regenerating the skin: a task for the heterogeneous stem cell pool and surrounding niche
    • Solanas G., Benitah S.A. Regenerating the skin: a task for the heterogeneous stem cell pool and surrounding niche. Nat. Rev. Mol. Cell Biol. 2013, 14:737-748.
    • (2013) Nat. Rev. Mol. Cell Biol. , vol.14 , pp. 737-748
    • Solanas, G.1    Benitah, S.A.2
  • 61
    • 0038625113 scopus 로고    scopus 로고
    • Transient activation of beta -catenin signaling in cutaneous keratinocytes is sufficient to trigger the active growth phase of the hair cycle in mice
    • Van Mater D., Kolligs F.T., Dlugosz A.A., Fearon E.R. Transient activation of beta -catenin signaling in cutaneous keratinocytes is sufficient to trigger the active growth phase of the hair cycle in mice. Genes Dev. 2003, 17:1219-1224.
    • (2003) Genes Dev. , vol.17 , pp. 1219-1224
    • Van Mater, D.1    Kolligs, F.T.2    Dlugosz, A.A.3    Fearon, E.R.4
  • 62
    • 68549127162 scopus 로고    scopus 로고
    • Role of beta-catenin in epidermal stem cell expansion, lineage selection, and cancer
    • Watt F.M., Collins C.A. Role of beta-catenin in epidermal stem cell expansion, lineage selection, and cancer. Cold Spring Harb. Symp. Quant. Biol. 2008, 73:503-512.
    • (2008) Cold Spring Harb. Symp. Quant. Biol. , vol.73 , pp. 503-512
    • Watt, F.M.1    Collins, C.A.2
  • 63
    • 77449119710 scopus 로고    scopus 로고
    • Epidermal stem cell diversity and quiescence
    • Watt F.M., Jensen K.B. Epidermal stem cell diversity and quiescence. EMBO Mol. Med. 2009, 1:260-267.
    • (2009) EMBO Mol. Med. , vol.1 , pp. 260-267
    • Watt, F.M.1    Jensen, K.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.