Mechanism of inhibition of the Drosophila and mammalian EGF receptors by the transmembrane protein Kekkon 1

Development

Volumn 130, Issue 18, 2003, Pages 4483-4493

  Ghiglione, Christian ^a,b   Amundadottir, Laufey ^a,c   Andresdottir, Margret ^c   Bilder, David ^a,d   Diamonti, John A ^e,f   Noselli, Stéphane ^b   Perrimon, Norbert ^a,g   Carraway III, Kermit L ^e,f  

^a HARVARD MEDICAL SCHOOL   (United States)

^b CENTRE DE BIOCHIMIE   (France)

^c DECODE GENETICS   (Iceland)

^d USA   (United States)

^e BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

EGFR; kek1; LRR domains; Mammary tumor; Negative feedback loop

Indexed keywords

CHIMERIC PROTEIN; CYTOPLASM PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH FACTOR RECEPTOR; KEKKON 1; LEUCINE; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KEK1; RAS PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BREAST TUMOR; CONTROLLED STUDY; DROSOPHILA; EMBRYO; IN VIVO STUDY; NEGATIVE FEEDBACK; NONHUMAN; OOCYTE DEVELOPMENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SCORING SYSTEM; SIGNAL TRANSDUCTION; TUMOR GROWTH;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELL LINE; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EMBRYONIC STRUCTURES; EPIDERMAL GROWTH FACTOR; FEEDBACK, BIOCHEMICAL; FEMALE; HUMANS; MEMBRANE PROTEINS; MICE; PHOTORECEPTORS, INVERTEBRATE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; WING;

MAMMALIA;

EID: 0141836766     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.00617     Document Type: Article

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