메뉴 건너뛰기




Volumn 8, Issue 9, 2013, Pages

Lrig2-Deficient Mice Are Protected against PDGFB-Induced Glioma

Author keywords

[No Author keywords available]

Indexed keywords

LEUCINE RICH REPEAT AND IMMUNOGLOBULIN LIKE DOMAIN PROTEIN 1; LEUCINE RICH REPEAT AND IMMUNOGLOBULIN LIKE DOMAIN PROTEIN 2; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN FOS; PROTEIN KINASE B; RETROVIRUS VECTOR; UNCLASSIFIED DRUG;

EID: 84883381112     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0073635     Document Type: Article
Times cited : (38)

References (40)
  • 1
    • 34347207046 scopus 로고    scopus 로고
    • LouisDN, OhgakiH, WiestlerOD, CavaneeWK (2007) WHO classification of tumours of the central nervous system. 4th ed. Lyon, France: International Agency for Research on Cancer. 309pp., Lyon, France, International Agency for Research on Cancer
    • Louis DN, Ohgaki H, Wiestler OD, Cavanee WK, (2007) WHO classification of tumours of the central nervous system. 4th ed. Lyon, France: International Agency for Research on Cancer. 309pp.
    • (2007) WHO Classification of Tumours of the Central Nervous System
    • Louis, D.N.1    Ohgaki, H.2    Wiestler, O.D.3    Cavanee, W.K.4
  • 2
    • 58149262943 scopus 로고    scopus 로고
    • Gliomas with 1p/19q codeletion: a.k.a. oligodendroglioma
    • 10.1097/PPO.0b013e31818d8178
    • Cairncross G, Jenkins R, (2008) Gliomas with 1p/19q codeletion: a.k.a. oligodendroglioma. Cancer J 14: 352-357. doi:10.1097/PPO.0b013e31818d8178. PubMed: 19060598.
    • (2008) Cancer J , vol.14 , pp. 352-357
    • Cairncross, G.1    Jenkins, R.2
  • 3
    • 0031951740 scopus 로고    scopus 로고
    • Platelet-derived growth factor and its receptor expression in human oligodendrogliomas
    • 10.1097/00006123-199802000-00080
    • Di Rocco F, Carroll RS, Zhang J, Black PM, (1998) Platelet-derived growth factor and its receptor expression in human oligodendrogliomas. Neurosurgery 42: 341-346. doi:10.1097/00006123-199802000-00080. PubMed: 9482185.
    • (1998) Neurosurgery , vol.42 , pp. 341-346
    • Di Rocco, F.1    Carroll, R.S.2    Zhang, J.3    Black, P.M.4
  • 4
    • 0032401819 scopus 로고    scopus 로고
    • Induction of brain tumors in mice using a recombinant platelet-derived growth factor B-chain retrovirus
    • 9850047
    • Uhrbom L, Hesselager G, Nistér M, Westermark B, (1998) Induction of brain tumors in mice using a recombinant platelet-derived growth factor B-chain retrovirus. Cancer Res 58: 5275-5279. PubMed: 9850047.
    • (1998) Cancer Res , vol.58 , pp. 5275-5279
    • Uhrbom, L.1    Hesselager, G.2    Nistér, M.3    Westermark, B.4
  • 5
    • 0035425048 scopus 로고    scopus 로고
    • PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo
    • 10.1101/gad.903001
    • Dai C, Celestino JC, Okada Y, Louis DN, Fuller GN, et al. (2001) PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo. Genes Dev 15: 1913-1925. doi:10.1101/gad.903001. PubMed: 11485986.
    • (2001) Genes Dev , vol.15 , pp. 1913-1925
    • Dai, C.1    Celestino, J.C.2    Okada, Y.3    Louis, D.N.4    Fuller, G.N.5
  • 6
    • 0029829132 scopus 로고    scopus 로고
    • cDNA cloning of a novel membrane glycoprotein that is expressed specifically in glial cells in the mouse brain. LIG-1, a protein with leucine-rich repeats and immunoglobulin-like domains
    • 10.1074/jbc.271.37.22522
    • Suzuki Y, Sato N, Tohyama M, Wanaka A, Takagi T, (1996) cDNA cloning of a novel membrane glycoprotein that is expressed specifically in glial cells in the mouse brain. LIG-1, a protein with leucine-rich repeats and immunoglobulin-like domains. J Biol Chem 271: 22522-22527. doi:10.1074/jbc.271.37.22522. PubMed: 8798419.
    • (1996) J Biol Chem , vol.271 , pp. 22522-22527
    • Suzuki, Y.1    Sato, N.2    Tohyama, M.3    Wanaka, A.4    Takagi, T.5
  • 7
    • 0034810996 scopus 로고    scopus 로고
    • Cloning, characterization, and expression of human LIG1
    • 10.1006/bbrc.2001.5092
    • Nilsson J, Vallbo C, Guo D, Golovleva I, Hallberg B, et al. (2001) Cloning, characterization, and expression of human LIG1. Biochem Biophys Res Commun 284: 1155-1161. doi:10.1006/bbrc.2001.5092. PubMed: 11414704.
    • (2001) Biochem Biophys Res Commun , vol.284 , pp. 1155-1161
    • Nilsson, J.1    Vallbo, C.2    Guo, D.3    Golovleva, I.4    Hallberg, B.5
  • 8
    • 2442526679 scopus 로고    scopus 로고
    • Characterization and tissue-specific expression of human LRIG2
    • 10.1016/j.gene.2004.02.002
    • Holmlund C, Nilsson J, Guo D, Starefeldt A, Golovleva I, et al. (2004) Characterization and tissue-specific expression of human LRIG2. Gene 332: 35-43. doi:10.1016/j.gene.2004.02.002. PubMed: 15145052.
    • (2004) Gene , vol.332 , pp. 35-43
    • Holmlund, C.1    Nilsson, J.2    Guo, D.3    Starefeldt, A.4    Golovleva, I.5
  • 9
    • 2942534392 scopus 로고    scopus 로고
    • The LRIG gene family has three vertebrate paralogs widely expressed in human and mouse tissues and a homolog in Ascidiacea
    • 10.1016/j.ygeno.2004.01.013
    • Guo D, Holmlund C, Henriksson R, Hedman H, (2004) The LRIG gene family has three vertebrate paralogs widely expressed in human and mouse tissues and a homolog in Ascidiacea. Genomics 84: 157-165. doi:10.1016/j.ygeno.2004.01.013. PubMed: 15203213.
    • (2004) Genomics , vol.84 , pp. 157-165
    • Guo, D.1    Holmlund, C.2    Henriksson, R.3    Hedman, H.4
  • 10
    • 20844462896 scopus 로고    scopus 로고
    • LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation
    • 10.1038/sj.emboj.7600342
    • Gur G, Rubin C, Katz M, Amit I, Citri A, et al. (2004) LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation. EMBO J 23: 3270-3281. doi:10.1038/sj.emboj.7600342. PubMed: 15282549.
    • (2004) EMBO J , vol.23 , pp. 3270-3281
    • Gur, G.1    Rubin, C.2    Katz, M.3    Amit, I.4    Citri, A.5
  • 11
    • 8744267487 scopus 로고    scopus 로고
    • The leucine-rich repeat protein LRIG1 is a negative regulator of ErbB family receptor tyrosine kinases
    • 10.1074/jbc.M409703200
    • Laederich MB, Funes-Duran M, Yen L, Ingalla E, Wu X, et al. (2004) The leucine-rich repeat protein LRIG1 is a negative regulator of ErbB family receptor tyrosine kinases. J Biol Chem 279: 47050-47056. doi:10.1074/jbc.M409703200. PubMed: 15345710.
    • (2004) J Biol Chem , vol.279 , pp. 47050-47056
    • Laederich, M.B.1    Funes-Duran, M.2    Yen, L.3    Ingalla, E.4    Wu, X.5
  • 12
    • 33847181657 scopus 로고    scopus 로고
    • LRIG1 is a novel negative regulator of the Met receptor and opposes Met and Her2 synergy
    • 10.1128/MCB.00757-06
    • Shattuck DL, Miller JK, Laederich M, Funes M, Petersen H, et al. (2007) LRIG1 is a novel negative regulator of the Met receptor and opposes Met and Her2 synergy. Mol Cell Biol 27: 1934-1946. doi:10.1128/MCB.00757-06. PubMed: 17178829.
    • (2007) Mol Cell Biol , vol.27 , pp. 1934-1946
    • Shattuck, D.L.1    Miller, J.K.2    Laederich, M.3    Funes, M.4    Petersen, H.5
  • 13
    • 38149041753 scopus 로고    scopus 로고
    • Lrig1 is an endogenous inhibitor of Ret receptor tyrosine kinase activation, downstream signaling, and biological responses to GDNF
    • 10.1523/JNEUROSCI.2196-07.2008
    • Ledda F, Bieraugel O, Fard SS, Vilar M, Paratcha G, (2008) Lrig1 is an endogenous inhibitor of Ret receptor tyrosine kinase activation, downstream signaling, and biological responses to GDNF. J Neurosci 28: 39-49. doi:10.1523/JNEUROSCI.2196-07.2008. PubMed: 18171921.
    • (2008) J Neurosci , vol.28 , pp. 39-49
    • Ledda, F.1    Bieraugel, O.2    Fard, S.S.3    Vilar, M.4    Paratcha, G.5
  • 14
    • 0036352654 scopus 로고    scopus 로고
    • Is LRIG1 a tumour suppressor gene at chromosome 3p14.3?
    • 10.1080/028418602760169398
    • Hedman H, Nilsson J, Guo D, Henriksson R, (2002) Is LRIG1 a tumour suppressor gene at chromosome 3p14.3? Acta Oncol 41: 352-354. doi:10.1080/028418602760169398. PubMed: 12234026.
    • (2002) Acta Oncol , vol.41 , pp. 352-354
    • Hedman, H.1    Nilsson, J.2    Guo, D.3    Henriksson, R.4
  • 15
    • 33947651745 scopus 로고    scopus 로고
    • LRIG inhibitors of growth factor signalling - double-edged swords in human cancer?
    • 10.1016/j.ejca.2006.10.021
    • Hedman H, Henriksson R, (2007) LRIG inhibitors of growth factor signalling- double-edged swords in human cancer? Eur J Cancer 43: 676-682. doi:10.1016/j.ejca.2006.10.021. PubMed: 17239582.
    • (2007) Eur J Cancer , vol.43 , pp. 676-682
    • Hedman, H.1    Henriksson, R.2
  • 16
    • 16844364208 scopus 로고    scopus 로고
    • LRIG-1 provides a novel prognostic predictor in squamous cell carcinoma of the skin: immunohistochemical analysis for 38 cases
    • 15871317
    • Tanemura A, Nagasawa T, Inui S, Itami S, (2005) LRIG-1 provides a novel prognostic predictor in squamous cell carcinoma of the skin: immunohistochemical analysis for 38 cases. Dermatol Surg 31: 423-430. PubMed: 15871317.
    • (2005) Dermatol Surg , vol.31 , pp. 423-430
    • Tanemura, A.1    Nagasawa, T.2    Inui, S.3    Itami, S.4
  • 17
    • 40549088610 scopus 로고    scopus 로고
    • LRIG1 and squamous epithelial uterine cervical cancer: correlation to prognosis, other tumor markers, sex steroid hormones, and smoking
    • 10.1111/j.1525-1438.2007.01021.x
    • Lindström AK, Ekman K, Stendahl U, Tot T, Henriksson R, et al. (2008) LRIG1 and squamous epithelial uterine cervical cancer: correlation to prognosis, other tumor markers, sex steroid hormones, and smoking. Int J Gynecol Cancer 18: 312-317. doi:10.1111/j.1525-1438.2007.01021.x. PubMed: 17624990.
    • (2008) Int J Gynecol Cancer , vol.18 , pp. 312-317
    • Lindström, A.K.1    Ekman, K.2    Stendahl, U.3    Tot, T.4    Henriksson, R.5
  • 18
    • 77952318977 scopus 로고    scopus 로고
    • Identifying common prognostic factors in genomic cancer studies: a novel index for censored outcomes
    • 10.1186/1471-2105-11-150
    • Rouam S, Moreau T, Broët P, (2010) Identifying common prognostic factors in genomic cancer studies: a novel index for censored outcomes. BMC Bioinformatics 11: 150. doi:10.1186/1471-2105-11-150. PubMed: 20334636.
    • (2010) BMC Bioinformatics , vol.11 , pp. 150
    • Rouam, S.1    Moreau, T.2    Broët, P.3
  • 19
    • 80054706404 scopus 로고    scopus 로고
    • Lrig1 is an estrogen-regulated growth suppressor and correlates with longer relapse-free survival in ERα-positive breast cancer
    • 10.1158/1541-7786.MCR-11-0227
    • Krig SR, Frietze S, Simion C, Miller JK, Fry WH, et al. (2011) Lrig1 is an estrogen-regulated growth suppressor and correlates with longer relapse-free survival in ERα-positive breast cancer. Mol Cancer Res 9: 1406-1417. doi:10.1158/1541-7786.MCR-11-0227. PubMed: 21821674.
    • (2011) Mol Cancer Res , vol.9 , pp. 1406-1417
    • Krig, S.R.1    Frietze, S.2    Simion, C.3    Miller, J.K.4    Fry, W.H.5
  • 20
    • 84873614833 scopus 로고    scopus 로고
    • Expression of LRIG1 and LRIG3 correlates with human papillomavirus status and patient survival in cervical adenocarcinoma
    • 23165628
    • Muller S, Lindquist D, Kanter L, Flores-Staino C, Henriksson R, et al. (2013) Expression of LRIG1 and LRIG3 correlates with human papillomavirus status and patient survival in cervical adenocarcinoma. Int J Oncol 42: 247-252. PubMed: 23165628.
    • (2013) Int J Oncol , vol.42 , pp. 247-252
    • Muller, S.1    Lindquist, D.2    Kanter, L.3    Flores-Staino, C.4    Henriksson, R.5
  • 21
    • 84859430024 scopus 로고    scopus 로고
    • Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling
    • 10.1038/ncb2464
    • Wong VW, Stange DE, Page ME, Buczacki S, Wabik A, et al. (2012) Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling. Nat Cell Biol 14: 401-408. doi:10.1038/ncb2464. PubMed: 22388892.
    • (2012) Nat Cell Biol , vol.14 , pp. 401-408
    • Wong, V.W.1    Stange, D.E.2    Page, M.E.3    Buczacki, S.4    Wabik, A.5
  • 22
    • 84859196824 scopus 로고    scopus 로고
    • The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor
    • 10.1016/j.cell.2012.02.042
    • Powell AE, Wang Y, Li Y, Poulin EJ, Means AL, et al. (2012) The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor. Cell 149: 146-158. doi:10.1016/j.cell.2012.02.042. PubMed: 22464327.
    • (2012) Cell , vol.149 , pp. 146-158
    • Powell, A.E.1    Wang, Y.2    Li, Y.3    Poulin, E.J.4    Means, A.L.5
  • 23
    • 33747047561 scopus 로고    scopus 로고
    • Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence
    • 10.1073/pnas.0601886103
    • Jensen KB, Watt FM, (2006) Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence. Proc Natl Acad Sci U S A 103: 11958-11963. doi:10.1073/pnas.0601886103. PubMed: 16877544.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 11958-11963
    • Jensen, K.B.1    Watt, F.M.2
  • 24
    • 65349166258 scopus 로고    scopus 로고
    • Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis
    • 10.1016/j.stem.2009.04.014
    • Jensen KB, Collins CA, Nascimento E, Tan DW, Frye M, et al. (2009) Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis. Cell Stem Cell 4: 427-439. doi:10.1016/j.stem.2009.04.014. PubMed: 19427292.
    • (2009) Cell Stem Cell , vol.4 , pp. 427-439
    • Jensen, K.B.1    Collins, C.A.2    Nascimento, E.3    Tan, D.W.4    Frye, M.5
  • 25
    • 18444370552 scopus 로고    scopus 로고
    • Targeted disruption of LIG-1 gene results in psoriasiform epidermal hyperplasia
    • 10.1016/S0014-5793(02)02824-7
    • Suzuki Y, Miura H, Tanemura A, Kobayashi K, Kondoh G, et al. (2002) Targeted disruption of LIG-1 gene results in psoriasiform epidermal hyperplasia. FEBS Lett 521: 67-71. doi:10.1016/S0014-5793(02)02824-7. PubMed: 12067728.
    • (2002) FEBS Lett , vol.521 , pp. 67-71
    • Suzuki, Y.1    Miura, H.2    Tanemura, A.3    Kobayashi, K.4    Kondoh, G.5
  • 26
    • 42149161161 scopus 로고    scopus 로고
    • Redistribution of LRIG proteins in psoriasis
    • 10.1038/sj.jid.5701175
    • Karlsson T, Mark EB, Henriksson R, Hedman H, (2008) Redistribution of LRIG proteins in psoriasis. J Invest Dermatol 128: 1192-1195. doi:10.1038/sj.jid.5701175. PubMed: 18037903.
    • (2008) J Invest Dermatol , vol.128 , pp. 1192-1195
    • Karlsson, T.1    Mark, E.B.2    Henriksson, R.3    Hedman, H.4
  • 27
    • 77953187849 scopus 로고    scopus 로고
    • Caenorhabditis elegans SMA-10/LRIG is a conserved transmembrane protein that enhances bone morphogenetic protein signaling
    • 6(5):e1000963, 20502686
    • Gumienny TL, Macneil L, Zimmerman CM, Wang H, Chin L, et al. (2010) Caenorhabditis elegans SMA-10/LRIG is a conserved transmembrane protein that enhances bone morphogenetic protein signaling. PLOS Genet 20: 6(5):e1000963. PubMed: 20502686.
    • (2010) PLOS Genet , vol.20
    • Gumienny, T.L.1    Macneil, L.2    Zimmerman, C.M.3    Wang, H.4    Chin, L.5
  • 28
    • 43049116136 scopus 로고    scopus 로고
    • Lrig3 regulates neural crest formation in Xenopus by modulating Fgf and Wnt signaling pathways
    • 10.1242/dev.015073
    • Zhao H, Tanegashima K, Ro H, Dawid IB, (2008) Lrig3 regulates neural crest formation in Xenopus by modulating Fgf and Wnt signaling pathways. Development 135: 1283-1293. doi:10.1242/dev.015073. PubMed: 18287203.
    • (2008) Development , vol.135 , pp. 1283-1293
    • Zhao, H.1    Tanegashima, K.2    Ro, H.3    Dawid, I.B.4
  • 29
    • 60849101584 scopus 로고    scopus 로고
    • Cross-repressive interactions between Lrig3 and netrin 1 shape the architecture of the inner ear
    • 10.1242/dev.029330
    • Abraira VE, Del Rio T, Tucker AF, Slonimsky J, Keirnes HL, et al. (2008) Cross-repressive interactions between Lrig3 and netrin 1 shape the architecture of the inner ear. Development 135: 4091-4099. doi:10.1242/dev.029330. PubMed: 19004851.
    • (2008) Development , vol.135 , pp. 4091-4099
    • Abraira, V.E.1    Del Rio, T.2    Tucker, A.F.3    Slonimsky, J.4    Keirnes, H.L.5
  • 30
    • 84873735633 scopus 로고    scopus 로고
    • LRIG2 Mutations Cause Urofacial Syndrome
    • 10.1016/j.ajhg.2012.12.002
    • Stuart HM, Roberts NA, Burgu B, Daly SB, Urquhart JE, et al. (2013) LRIG2 Mutations Cause Urofacial Syndrome. Am J Hum Genet 92: 259-264. doi:10.1016/j.ajhg.2012.12.002. PubMed: 23313374.
    • (2013) Am J Hum Genet , vol.92 , pp. 259-264
    • Stuart, H.M.1    Roberts, N.A.2    Burgu, B.3    Daly, S.B.4    Urquhart, J.E.5
  • 31
    • 65649148276 scopus 로고    scopus 로고
    • Cytoplasmic LRIG2 expression is associated with poor oligodendroglioma patient survival
    • 10.1111/j.1440-1789.2008.00970.x
    • Holmlund C, Haapasalo H, Yi W, Raheem O, Brännström T, et al. (2009) Cytoplasmic LRIG2 expression is associated with poor oligodendroglioma patient survival. Neuropathology 29: 242-247. doi:10.1111/j.1440-1789.2008.00970.x. PubMed: 18992012.
    • (2009) Neuropathology , vol.29 , pp. 242-247
    • Holmlund, C.1    Haapasalo, H.2    Yi, W.3    Raheem, O.4    Brännström, T.5
  • 32
    • 77954472069 scopus 로고    scopus 로고
    • LRIG2 in contrast to LRIG1 predicts poor survival in early-stage squamous cell carcinoma of the uterine cervix
    • 10.3109/0284186X.2010.492789
    • Hedman H, Lindström AK, Tot T, Stendahl U, Henriksson R, et al. (2010) LRIG2 in contrast to LRIG1 predicts poor survival in early-stage squamous cell carcinoma of the uterine cervix. Acta Oncol 49: 812-815. doi:10.3109/0284186X.2010.492789. PubMed: 20553099.
    • (2010) Acta Oncol , vol.49 , pp. 812-815
    • Hedman, H.1    Lindström, A.K.2    Tot, T.3    Stendahl, U.4    Henriksson, R.5
  • 34
    • 0032418416 scopus 로고    scopus 로고
    • A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice
    • 10.1101/gad.12.23.3675
    • Holland EC, Hively WP, DePinho RA, Varmus HE, (1998) A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice. Genes Dev 12: 3675-3685. doi:10.1101/gad.12.23.3675. PubMed: 9851974.
    • (1998) Genes Dev , vol.12 , pp. 3675-3685
    • Holland, E.C.1    Hively, W.P.2    DePinho, R.A.3    Varmus, H.E.4
  • 35
    • 34648834721 scopus 로고    scopus 로고
    • Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma
    • 10.1038/sj.onc.1210455
    • Tchougounova E, Kastemar M, Bråsäter D, Holland EC, Westermark B, et al. (2007) Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma. Oncogene 26: 6289-6296. doi:10.1038/sj.onc.1210455. PubMed: 17438529.
    • (2007) Oncogene , vol.26 , pp. 6289-6296
    • Tchougounova, E.1    Kastemar, M.2    Bråsäter, D.3    Holland, E.C.4    Westermark, B.5
  • 36
    • 27144529532 scopus 로고    scopus 로고
    • PDGFRalphaalpha signaling is regulated through the primary cilium in fibroblasts
    • 10.1016/j.cub.2005.09.012
    • Schneider L, Clement CA, Teilmann SC, Pazour GJ, Hoffmann EK, et al. (2005) PDGFRalphaalpha signaling is regulated through the primary cilium in fibroblasts. Curr Biol 15: 1861-1866. doi:10.1016/j.cub.2005.09.012. PubMed: 16243034.
    • (2005) Curr Biol , vol.15 , pp. 1861-1866
    • Schneider, L.1    Clement, C.A.2    Teilmann, S.C.3    Pazour, G.J.4    Hoffmann, E.K.5
  • 37
    • 40549136002 scopus 로고    scopus 로고
    • Reduced body weight is a common effect of gene knockout in mice
    • 10.1186/1471-2156-9-4
    • Reed DR, Lawler MP, Tordoff MG, (2008) Reduced body weight is a common effect of gene knockout in mice. BMC Genet 9: 4. doi:10.1186/1471-2156-9-4. PubMed: 18182103.
    • (2008) BMC Genet , vol.9 , pp. 4
    • Reed, D.R.1    Lawler, M.P.2    Tordoff, M.G.3
  • 38
    • 61749100091 scopus 로고    scopus 로고
    • Alterations in cell growth and signaling in ErbB3 binding protein-1 (Ebp1) deficient mice
    • 10.1186/1471-2121-9-69
    • Zhang Y, Lu Y, Zhou H, Lee M, Liu Z, et al. (2008) Alterations in cell growth and signaling in ErbB3 binding protein-1 (Ebp1) deficient mice. BMC Cell Biol 9: 69. doi:10.1186/1471-2121-9-69. PubMed: 19094237.
    • (2008) BMC Cell Biol , vol.9 , pp. 69
    • Zhang, Y.1    Lu, Y.2    Zhou, H.3    Lee, M.4    Liu, Z.5
  • 39
    • 0031923473 scopus 로고    scopus 로고
    • Transient dwarfism and hypogonadism in mice lacking Otx1 reveal prepubescent stage-specific control of pituitary levels of GH, FSH and LH
    • 9477321
    • Acampora D, Mazan S, Tuorto F, Avantaggiato V, Tremblay JJ, et al. (1998) Transient dwarfism and hypogonadism in mice lacking Otx1 reveal prepubescent stage-specific control of pituitary levels of GH, FSH and LH. Development 125: 1229-1239. PubMed: 9477321.
    • (1998) Development , vol.125 , pp. 1229-1239
    • Acampora, D.1    Mazan, S.2    Tuorto, F.3    Avantaggiato, V.4    Tremblay, J.J.5
  • 40
    • 3142713010 scopus 로고    scopus 로고
    • Dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesis
    • 10.1158/0008-5472.CAN-03-3831
    • Shih AH, Dai C, Hu X, Rosenblum MK, Koutcher JA, et al. (2004) Dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesis. Cancer Res 64: 4783-4789. doi:10.1158/0008-5472.CAN-03-3831. PubMed: 15256447.
    • (2004) Cancer Res , vol.64 , pp. 4783-4789
    • Shih, A.H.1    Dai, C.2    Hu, X.3    Rosenblum, M.K.4    Koutcher, J.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.