Engineering of temperature- and light-switchable Cas9 variants

Nucleic Acids Research

Volumn 44, Issue 20, 2013, Pages 10003-10014

  Richter, Florian ^a   Fonfara, Ines ^b,c   Bouazza, Boris ^a   Schumacher, Charlotte Helene ^a   Bratovič, Majda ^b   Charpentier, Emmanuelle ^b,c   Möglich, Andreas ^a,d  

^a HUMBOLDT UNIVERSITY   (Germany)

^b MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

^c UMEÅ UNIVERSITY   (Sweden)

^d UNIVERSITY OF BAYREUTH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CAS9 PROTEIN; DEOXYRIBONUCLEASE; ENZYME VARIANT; UNCLASSIFIED DRUG; ENDONUCLEASE;

ARTICLE; BLUE LIGHT; CONTROLLED STUDY; DNA BINDING; DNA CLEAVAGE; ENZYME ACTIVITY; ENZYME ENGINEERING; LIGHT EXPOSURE; NONHUMAN; PHOTORECEPTOR; PROTEIN STRUCTURE; TEMPERATURE DEPENDENCE; TEMPERATURE SENSITIVITY; TRANSCRIPTION REGULATION; AMINO ACID SEQUENCE; CHEMISTRY; ENZYMOLOGY; FLOW CYTOMETRY; GENE EXPRESSION; GENETIC VARIATION; GENETICS; HIGH THROUGHPUT SCREENING; ISOLATION AND PURIFICATION; LIGHT; METABOLISM; MOLECULAR MODEL; MUTATION; PROTEIN CONFORMATION; PROTEIN ENGINEERING; RADIATION RESPONSE; RHODOBACTER SPHAEROIDES; TEMPERATURE;

AMINO ACID SEQUENCE; DNA CLEAVAGE; ENDONUCLEASES; FLOW CYTOMETRY; GENE EXPRESSION; GENETIC VARIATION; HIGH-THROUGHPUT SCREENING ASSAYS; LIGHT; MODELS, MOLECULAR; MUTATION; PROTEIN CONFORMATION; PROTEIN ENGINEERING; RHODOBACTER SPHAEROIDES; TEMPERATURE;

EID: 85014520594     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkw930     Document Type: Article

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